Mamoru Nakanishi

Summary

Affiliation: Nagoya City University
Country: Japan

Publications

  1. ncbi request reprint Dynamics of intracellular granules with CD63-GFP in rat basophilic leukemia cells
    T Amano
    Faculty of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Biochem 129:739-44. 2001
  2. ncbi request reprint Confocal and probe microscopy to study gene transfection mediated by cationic liposomes with a cationic cholesterol derivative
    M Nakanishi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Adv Drug Deliv Rev 52:197-207. 2001
  3. ncbi request reprint New strategy in gene transfection by cationic transfection lipids with a cationic cholesterol
    Mamoru Nakanishi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Curr Med Chem 10:1289-96. 2003
  4. ncbi request reprint NBD-conjugated biosurfactant (MEL-A) shows a new pathway for transfection
    Yoshinobu Ueno
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Control Release 123:247-53. 2007
  5. ncbi request reprint Flotillin-1 regulates IgE receptor-mediated signaling in rat basophilic leukemia (RBL-2H3) cells
    Naoto Kato
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Immunol 177:147-54. 2006
  6. ncbi request reprint Effects of Cot expression on the nuclear translocation of NF-kappaB in RBL-2H3 cells
    Satomi Chikamatsu
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Mol Immunol 44:1490-7. 2007
  7. ncbi request reprint The spermatogenic Ig superfamily/synaptic cell adhesion molecule mast-cell adhesion molecule promotes interaction with nerves
    Tadahide Furuno
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
    J Immunol 174:6934-42. 2005
  8. ncbi request reprint Complexin II facilitates exocytotic release in mast cells by enhancing Ca2+ sensitivity of the fusion process
    Satoshi Tadokoro
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Cell Sci 118:2239-46. 2005
  9. ncbi request reprint Anchoring cationic amphiphiles for nucleotide delivery: significance of DNA release from cationic liposomes for transfection
    Naohide Hirashima
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
    Biol Pharm Bull 30:1117-22. 2007
  10. ncbi request reprint Asialoganglioside enhances the efficiency of gene transfection mediated by cationic liposomes with a cationic cholesterol derivative
    Shoichiro Noguchi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
    Biol Pharm Bull 26:1306-10. 2003

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Dynamics of intracellular granules with CD63-GFP in rat basophilic leukemia cells
    T Amano
    Faculty of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Biochem 129:739-44. 2001
    ..1+/-0.02 microm/s. This shows that the granules are able to reach the plasma membranes in 2 or 3 min if the diameter of the cells is 20 microm...
  2. ncbi request reprint Confocal and probe microscopy to study gene transfection mediated by cationic liposomes with a cationic cholesterol derivative
    M Nakanishi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Adv Drug Deliv Rev 52:197-207. 2001
    ..In addition we found that microtubules were involved in the intracellular dynamics of gene transfection...
  3. ncbi request reprint New strategy in gene transfection by cationic transfection lipids with a cationic cholesterol
    Mamoru Nakanishi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Curr Med Chem 10:1289-96. 2003
    ....
  4. ncbi request reprint NBD-conjugated biosurfactant (MEL-A) shows a new pathway for transfection
    Yoshinobu Ueno
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Control Release 123:247-53. 2007
    ..Thereafter, the oligonucleotide released from the vesicles was immediately transferred to the nucleus. The present results showed a new role of non-viral vectors in transfection...
  5. ncbi request reprint Flotillin-1 regulates IgE receptor-mediated signaling in rat basophilic leukemia (RBL-2H3) cells
    Naoto Kato
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Immunol 177:147-54. 2006
    ..These results suggest that flotillin-1 is an essential molecule in IgE receptor-mediated mast cell activation, and regulates the kinase activity of Lyn in lipid rafts...
  6. ncbi request reprint Effects of Cot expression on the nuclear translocation of NF-kappaB in RBL-2H3 cells
    Satomi Chikamatsu
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Mol Immunol 44:1490-7. 2007
    ..This finding gives a new insight into the role of Cot in the FcvarepsilonRI-mediated NF-kappaB activation in mast cells...
  7. ncbi request reprint The spermatogenic Ig superfamily/synaptic cell adhesion molecule mast-cell adhesion molecule promotes interaction with nerves
    Tadahide Furuno
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
    J Immunol 174:6934-42. 2005
    ..At points of contact between neurites and wild-type BMMC, SgIGSF/SynCAM was locally concentrated in both neurites and BMMC. SgIGSF/SynCAM on mast cells appeared to predominantly mediate attachment and promote communication with nerves...
  8. ncbi request reprint Complexin II facilitates exocytotic release in mast cells by enhancing Ca2+ sensitivity of the fusion process
    Satoshi Tadokoro
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Cell Sci 118:2239-46. 2005
    ....
  9. ncbi request reprint Anchoring cationic amphiphiles for nucleotide delivery: significance of DNA release from cationic liposomes for transfection
    Naohide Hirashima
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
    Biol Pharm Bull 30:1117-22. 2007
    ..Thus, the efficiency of release of DNA from cationic liposomes in the cytoplasm, which contributes to high transfection efficiency, appears to be dependent upon the molecular shape of the cationic amphiphiles...
  10. ncbi request reprint Asialoganglioside enhances the efficiency of gene transfection mediated by cationic liposomes with a cationic cholesterol derivative
    Shoichiro Noguchi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
    Biol Pharm Bull 26:1306-10. 2003
    ..Together with the results obtained by luciferase assay mentioned above, the removal of sialic acid from ganglioside causes the enhancement of efficiency of transfection mediated by cationic liposomes...
  11. ncbi request reprint Calcium response and FcepsilonRI expression in bone marrow-derived mast cells co-cultured with SCG neurites
    Akio Suzuki
    Graduate School of Pharmaceutical Sciences, Nagoya City University Nagoya 467 8603, Japan
    Biol Pharm Bull 28:1963-5. 2005
    ..All of these results indicated that co-culturing BMMCs with SCG neurites for 3 d promoted not only the calcium response but also the FcepsilonRI expression in BMMCs...
  12. ncbi request reprint Effects of menadione, a reactive oxygen generator, on leukotriene secretion from RBL-2H3 cells
    Fumio Kawamura
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Biol Pharm Bull 33:881-5. 2010
    ....
  13. doi request reprint Inhibition of degranulation and cytokine production in bone marrow-derived mast cells by hydrolyzed rice bran
    Yuka Hoshino
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho ku, Nagoya, Japan
    Inflamm Res 59:615-25. 2010
    ..We investigated the effects of hydrolyzed rice bran (HRB), an arabinoxylan extracted from rice bran, on mast cell degranulation and cytokine production...
  14. ncbi request reprint Characterization of biosurfactant-containing liposomes and their efficiency for gene transfection
    Yoshinobu Ueno
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
    Biol Pharm Bull 30:169-72. 2007
    ..The results indicated that these kinds of the physicochemical properties in MEL-A-containing liposomes are able to increase the efficiency of liposome-mediated gene transfection...
  15. doi request reprint Complexin II regulates degranulation in RBL-2H3 cells by interacting with SNARE complex containing syntaxin-3
    Satoshi Tadokoro
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Cell Immunol 261:51-6. 2010
    ..These results suggest that complexin II regulates degranulation by interacting with the SNARE complex containing syntaxin-3...
  16. ncbi request reprint ATP plays a role in neurite stimulation with activated mast cells
    Ryo Suzuki
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467 8603, Japan
    J Neuroimmunol 192:49-56. 2007
    ....
  17. ncbi request reprint Neurotrophic factors increase tumor necrosis factor-alpha-induced nuclear translocation of NF-kappaB in rat PC12 cells
    Tadahide Furuno
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori
    Neurosci Lett 392:240-4. 2006
    ....
  18. doi request reprint Latrotoxin-induced exocytosis in mast cells transfected with latrophilin
    Hiroyuki Hiramatsu
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Toxicon 56:1372-80. 2010
    ..Our study may provide a new system to investigate the action of α-LTX and the mechanism of exocytosis in mast cells...
  19. ncbi request reprint Remarkable induction of apoptosis in cancer cells by a novel cationic liposome complexed with a bcl-2 antisense oligonucleotide
    Shoichiro Noguchi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Japan
    J Control Release 88:313-20. 2003
    ..The results showed the possibility that this new cationic cholesterol derivative might be very promising to be used for liposome-mediated gene targeting in vitro and in vivo...
  20. ncbi request reprint Cholesterol depletion inhibits store-operated calcium currents and exocytotic membrane fusion in RBL-2H3 cells
    Naoto Kato
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Biochemistry 42:11808-14. 2003
    ..These results suggest that cholesterol depletion by MbetaCD decreases degranulation mainly by inhibiting the SOC and membrane fusion between the secretory granules and the plasma membrane in mast cells...
  21. ncbi request reprint Munc18-2 regulates exocytotic membrane fusion positively interacting with syntaxin-3 in RBL-2H3 cells
    Satoshi Tadokoro
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Mol Immunol 44:3427-33. 2007
    ....
  22. ncbi request reprint Biosurfactant MEL-A dramatically increases gene transfection via membrane fusion
    Yoshikazu Inoh
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Control Release 94:423-31. 2004
    ..This suggests that MEL-A induces the membrane fusion between the target cells and the cationic liposomes, accelerating the efficiency of gene transfection dramatically...
  23. ncbi request reprint Transbilayer asymmetry of phospholipids in the plasma membrane regulates exocytotic release in mast cells
    Naoto Kato
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Biochemistry 41:8068-74. 2002
    ..This finding also demonstrates that the transbilayer asymmetry of phospholipids regulates exocytosis and gives a new insight into the significance of lipid asymmetry in the plasma membrane...
  24. ncbi request reprint Activation of receptor tyrosine kinases promotes gene transfection in rat neuronal PC12 cells by cationic liposomes
    Ari Noguchi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya, 467 8603, Japan
    Neurosci Lett 325:29-32. 2002
    ..It is supposed that the novel liposomes with the derivative (I) will be useful to study the problems in neuron and neuronal tissues for gene transfection...
  25. ncbi request reprint Live cell imaging to study signaling molecules in allergic reactions
    Tadahide Furuno
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
    Biol Pharm Bull 28:1551-9. 2005
    ....
  26. ncbi request reprint N-cadherin plays a role in the synapse-like structures between mast cells and neurites
    Akio Suzuki
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
    Biol Pharm Bull 27:1891-4. 2004
    ..In addition, we found that the synapse-like structure was assisted by clustering of beta-catenin to N-cadherin...
  27. ncbi request reprint Effects of 2-methyl-1,4-naphtoquinone (menadione) on cellular signaling in RBL-2H3 cells
    Fumio Kawamura
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Japan
    Biol Pharm Bull 29:605-7. 2006
    ..These results suggest that reactive oxygen generated inside RBL cells by menadione inhibited degranulation by decreasing Ca2+ influx through the store operated Ca2+ channel on the plasma membrane...
  28. ncbi request reprint The effects of ITIM-bearing FcgammaRIIB on the nuclear shuttling of MAP kinase in RBL-2H3 cells
    Nobuyuki Ohyama
    Faculty of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Immunol Lett 90:173-6. 2003
    ..This suggested that the co-clustering negatively control the production of pro-inflammatory cytokines through the suppression of nuclear shuttling of ERK2...
  29. ncbi request reprint [Functional fluctuation]
    Mamoru Nakanishi
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Yakugaku Zasshi 126:379-93. 2006
    ..This new theme is pretty well supported by our recent experiments for neuro-immune crosstalk, gene transfection with cationic liposomes, and cell signaling in embryonic stem cells...
  30. doi request reprint Role of mu-calpain in human decidua for recurrent miscarriage
    Kyoko Kumagai
    Department of Obstetrics and Gynecology, Nagoya City University, Mizuho ku, Nagoya, Japan
    Am J Reprod Immunol 59:339-46. 2008
    ..In the present study, we investigated the existence and distribution of calpains, calpastatin, integrin beta3 and alpha-fodrin in decidua from patients with recurrent miscarriage...
  31. ncbi request reprint The plasma membrane shuttling of CAPRI is related to regulation of mast cell activation
    Rika Nakamura
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho ku, Japan
    Biochem Biophys Res Commun 347:363-8. 2006
    ..The results suggested that the translocation of CAPRI to the plasma membranes regulates crucially cellular responses in mast cells...
  32. ncbi request reprint Comparative study of transfection efficiency of cationic cholesterols mediated by liposomes-based gene delivery
    Seiji Hasegawa
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, 467 8603, Nagoya, Japan
    Bioorg Med Chem Lett 12:1299-302. 2002
    ..We also found that the introduction of a hydrophilic group to the amino terminal of the cholesterol derivative decreased stability and facilitated the release of DNA from the endosome, resulting in higher transfection efficiency...
  33. ncbi request reprint Conditioned medium from feeder STO cells increases the attachment of mouse embryonic stem cells
    Kenichiro Amano
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
    Biol Pharm Bull 29:1747-50. 2006
    ..In addition, from present experiments we found that the dish double-coated with gelatin and CM was extremely useful for culturing ES cells...
  34. doi request reprint Effect of NeuroD2 expression on neuronal differentiation in mouse embryonic stem cells
    Yasutaka Sugimoto
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Cell Biol Int 33:174-9. 2009
    ..The results suggest that the expression of NeuroD2 requires an appropriate period of about 3 days to elicit neuronal differentiation in ES cells...
  35. doi request reprint Phosphorylation states of STAT3 and ERKs in mouse embryonic stem cells
    Sakiko Miyazu
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuhoku, Nagoya, Japan
    Cell Biol Int 34:485-92. 2010
    ..These results suggested that LIF-induced SOCS3 suppressed the ERKs activation pathway in undifferentiated ES cells, and the down-regulation of SOCS3 by the removal of LIF triggered the phosphorylation of ERKs...
  36. ncbi request reprint Bone marrow-derived mast cells in mice respond in co-culture to scorpion venom activation of superior cervical ganglion neurites according to level of expression of NK-1 receptors
    Tadahide Furuno
    Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
    Neurosci Lett 372:185-9. 2004
    ..Our findings show that the expression of NK-1 receptors appears to be important for nerve-mast cell communication...
  37. ncbi request reprint Cationic cholesterol promotes gene transfection using the nuclear localization signal in protamine
    Ari Noguchi
    Graduate School of Pharmaceutical Sciences Nagoya City University, Nagoya, Japan
    Pharm Res 19:933-8. 2002
    ..The purpose of this study was to evaluate protamine-mediated gene transfection by liposomes with a novel cationic cholesterol derivative (I) compared to those with DC-Chol or DOTMA (Lipofectin)...
  38. doi request reprint Molecular basis of neuroimmune interaction in an in vitro coculture approach
    Mamoru Nakanishi
    School of Pharmacy, Aichi Gakuin University, 1 100 Kusumoto cho, Chikusa ku, Nagoya 464 8650, Japan
    Cell Mol Immunol 5:249-59. 2008
    ..It would lead to new therapeutic modalities for diseases based on neuroimmune interaction such as neurogenic inflammation, intestinal bowel diseases, asthma, and autoimmune disorders...
  39. ncbi request reprint The ratio of serum paraoxonase/arylesterase activity using an improved assay for arylesterase activity to discriminate PON1(R192) from PON1(Q192)
    Mamoru Nakanishi
    Department of Clinical Pathology, Hyogo College of Medicine, Hyogo, Japan
    J Atheroscler Thromb 10:337-42. 2003
    ..Therefore, when conducting epidemiological or mechanistic studies that examine the role of PON1 in organophosphorus or lipid metabolism, this ratio is more useful and informative than a PCR-based genotype alone...