M Nagino

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. doi request reprint Percutaneous transhepatic biliary drainage catheter tract recurrence in cholangiocarcinoma
    Y Takahashi
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Br J Surg 97:1860-6. 2010
  2. ncbi request reprint Randomized controlled trial on timing and number of sampling for bile aspiration cytology
    Tomonori Tsuchiya
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    J Hepatobiliary Pancreat Sci 21:433-8. 2014
  3. pmc Optimal schedule of adjuvant chemotherapy with S-1 for stage III colon cancer: study protocol for a randomized controlled trial
    Kenichi Yoshimura
    Department of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, 54 Shogoin Kawahara, Sakyo, Kyoto, 606 8507, Japan
    Trials 14:17. 2013
  4. doi request reprint Evolution of surgical treatment for perihilar cholangiocarcinoma: a single-center 34-year review of 574 consecutive resections
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 258:129-40. 2013
  5. doi request reprint Perihilar cholangiocarcinoma: a surgeon's viewpoint on current topics
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    J Gastroenterol 47:1165-76. 2012
  6. ncbi request reprint One hundred consecutive hepatobiliary resections for biliary hilar malignancy: preoperative blood donation, blood loss, transfusion, and outcome
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Surgery 137:148-55. 2005
  7. pmc Two hundred forty consecutive portal vein embolizations before extended hepatectomy for biliary cancer: surgical outcome and long-term follow-up
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 243:364-72. 2006
  8. ncbi request reprint Complications of hepatectomy for hilar cholangiocarcinoma
    M Nagino
    First Department of Surgery, Nagoya University School of Medicine, Japan
    World J Surg 25:1277-83. 2001
  9. ncbi request reprint Liver regeneration after major hepatectomy for biliary cancer
    M Nagino
    First Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Br J Surg 88:1084-91. 2001
  10. ncbi request reprint Hepaticojejunostomy using a Roux-en-Y jejunal limb via the retrocolic-retrogastric route
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466, Japan
    Langenbecks Arch Surg 387:188-9. 2002

Collaborators

Detail Information

Publications118 found, 100 shown here

  1. doi request reprint Percutaneous transhepatic biliary drainage catheter tract recurrence in cholangiocarcinoma
    Y Takahashi
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Br J Surg 97:1860-6. 2010
    ..The aim of the study was to clarify the incidence, risk factors and treatment of percutaneous transhepatic biliary drainage (PTBD) catheter tract recurrence in patients with resected cholangiocarcinoma...
  2. ncbi request reprint Randomized controlled trial on timing and number of sampling for bile aspiration cytology
    Tomonori Tsuchiya
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    J Hepatobiliary Pancreat Sci 21:433-8. 2014
    ..The issue on timing and number of bile sampling for exfoliative bile cytology is still unsettled...
  3. pmc Optimal schedule of adjuvant chemotherapy with S-1 for stage III colon cancer: study protocol for a randomized controlled trial
    Kenichi Yoshimura
    Department of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, 54 Shogoin Kawahara, Sakyo, Kyoto, 606 8507, Japan
    Trials 14:17. 2013
    ..Therefore, we will conduct a multicenter randomized phase II trial to compare six-week and three-week cycles to establish the optimal schedule of S-1 adjuvant therapy for patients with stage III colon cancer after curative resection...
  4. doi request reprint Evolution of surgical treatment for perihilar cholangiocarcinoma: a single-center 34-year review of 574 consecutive resections
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 258:129-40. 2013
    ..To review our 34-year experience with 574 consecutive resections for perihilar cholangiocarcinoma and to evaluate the progress made in surgical treatment of this disease...
  5. doi request reprint Perihilar cholangiocarcinoma: a surgeon's viewpoint on current topics
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    J Gastroenterol 47:1165-76. 2012
    ..Further synergy of endoscopists, radiologists, oncologists, and surgeons is required to conquer this intractable disease...
  6. ncbi request reprint One hundred consecutive hepatobiliary resections for biliary hilar malignancy: preoperative blood donation, blood loss, transfusion, and outcome
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Surgery 137:148-55. 2005
    ..The aim of this study was to review our experience with blood loss and perioperative blood requirements in 100 consecutive hepatectomies for biliary hilar malignancy...
  7. pmc Two hundred forty consecutive portal vein embolizations before extended hepatectomy for biliary cancer: surgical outcome and long-term follow-up
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 243:364-72. 2006
    ..To assess clinical benefit of portal vein embolization (PVE) before extended, complex hepatectomy for biliary cancer...
  8. ncbi request reprint Complications of hepatectomy for hilar cholangiocarcinoma
    M Nagino
    First Department of Surgery, Nagoya University School of Medicine, Japan
    World J Surg 25:1277-83. 2001
    ..Our goal is to reduce mortality to less than 5% while keeping a high resectability rate (above 80%)...
  9. ncbi request reprint Liver regeneration after major hepatectomy for biliary cancer
    M Nagino
    First Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Br J Surg 88:1084-91. 2001
    ..The aim of this study was to evaluate serial changes in liver volume after major hepatectomy for biliary cancer and to elucidate clinical factors influencing liver regeneration...
  10. ncbi request reprint Hepaticojejunostomy using a Roux-en-Y jejunal limb via the retrocolic-retrogastric route
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466, Japan
    Langenbecks Arch Surg 387:188-9. 2002
    ..However, in morbidly obese patients difficulty arises from the thickened, foreshortened mesentery of the jejunum and from limited mobility due to intra-abdominal fat deposition...
  11. ncbi request reprint Perihilar cholangiocarcinoma: A much needed but imperfect new staging system
    Masato Nagino
    Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Japan
    Nat Rev Gastroenterol Hepatol 8:252-3. 2011
    ..However, the system has several flaws; thus, many revisions are needed before a registry can be established that uses this system...
  12. ncbi request reprint Intrahepatic cholangiojejunostomy following hepatobiliary resection
    M Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Br J Surg 94:70-7. 2007
    ..The aim of this study was to evaluate the incidence of anastomotic leak after intrahepatic cholangiojejunostomy and to identify risk factors for such leakage...
  13. doi request reprint Hepatectomy with simultaneous resection of the portal vein and hepatic artery for advanced perihilar cholangiocarcinoma: an audit of 50 consecutive cases
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 252:115-23. 2010
    ..To outline our experience with hepatectomy with simultaneous resection of the portal vein and hepatic artery for advanced perihilar cholangiocarcinoma, and to discuss the clinical significance of this challenging hepatectomy...
  14. pmc "Anatomic" right hepatic trisectionectomy (extended right hepatectomy) with caudate lobectomy for hilar cholangiocarcinoma
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 243:28-32. 2006
    ..The techniques of right hepatic trisectionectomy are now standardized in patients with hepatocellular or metastatic carcinoma, but not in those with hilar cholangiocarcinoma...
  15. ncbi request reprint Five-year survivors after aggressive surgery for stage IV gallbladder cancer
    S Kondo
    First Department of Surgery, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
    J Hepatobiliary Pancreat Surg 8:511-7. 2001
    ....
  16. pmc Lymph node metastasis from hilar cholangiocarcinoma: audit of 110 patients who underwent regional and paraaortic node dissection
    Y Kitagawa
    First Department of Surgery, Nagoya University School of Medicine, Nagoya, Japan
    Ann Surg 233:385-92. 2001
    ..However, the fact that long-term survival is possible despite pN2 or pM1 disease encourages the authors to perform an aggressive surgical procedure with extended lymph node dissection in selected patients with hilar cholangiocarcinoma...
  17. ncbi request reprint Percutaneous cholangioscopic bilioenterostomy for unreconstructed segmental bile duct after hepatobiliary resection for hilar cholangiocarcinoma
    T Sano
    First Department of Surgery, Nagoya University Graduate School of Medicine, Japan
    Endoscopy 33:284-8. 2001
    ..We present here our technique of percutaneous transhepatic bilioenterostomy...
  18. ncbi request reprint Asymptomatic portal vein obstruction after hepatobiliary resection: early detection by Doppler ultrasonography
    Y Kito
    First Department of Surgery, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
    Hepatogastroenterology 48:550-2. 2001
    ..The two cases of portal vein obstruction were asymptomatic without any suggestive laboratory findings. Only routine Doppler ultrasonography detected portal vein obstruction which was successfully treated by emergency operation...
  19. ncbi request reprint Doppler sonography of hepatic arterial blood flow velocity after percutaneous transhepatic portal vein embolization
    Y Kito
    First Department of Surgey, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
    AJR Am J Roentgenol 176:909-12. 2001
    ..This observation may be explained by the simple mechanical effect of interposing a slower flowing stream (portal flow) in the path of a faster flowing stream (arterial flow)...
  20. ncbi request reprint Perineural invasion has a negative impact on survival of patients with gallbladder carcinoma
    R Yamaguchi
    Department of Surgery, Division of Surgical Oncology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Br J Surg 89:1130-6. 2002
    ..The aim of this study was to elucidate the incidence and mode of perineural invasion of gallbladder carcinoma and clarify its prognostic significance...
  21. ncbi request reprint Hepatocellular carcinoma with biliary tumor thrombi: aggressive operative approach after appropriate preoperative management
    M Shiomi
    First Department of Surgery, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
    Surgery 129:692-8. 2001
    ..Hepatectomy with thrombectomy through a choledochotomy appears to be as effective as a resection procedure...
  22. doi request reprint New classification of cystic duct carcinoma
    Y Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    World J Surg 32:621-6. 2008
    ..In this study, we further propose a new classification for cystic duct carcinomas diagnosed by our definition...
  23. doi request reprint The concept of perihilar cholangiocarcinoma is valid
    T Ebata
    Department of Surgery, Division of Surgical Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Br J Surg 96:926-34. 2009
    ..However, it does not distinguish between intrahepatic and extrahepatic hilar tumours, and has no clinicopathological basis. This retrospective study examined whether the concept of perihilar cholangiocarcinoma is valid clinically...
  24. doi request reprint Role of anatomical right hepatic trisectionectomy for perihilar cholangiocarcinoma
    N Matsumoto
    Division of Surgical Oncology, Department of Surgery, Nagoya, Japan
    Br J Surg 101:261-8. 2014
    ..However, the length of resected left hepatic duct in right-sided hepatectomy has not been reported...
  25. ncbi request reprint Extensive surgery for carcinoma of the gallbladder
    S Kondo
    First Department of Surgery, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Br J Surg 89:179-84. 2002
    ..The purpose of this study was to clarify the efficacy of, and define the indications for, extensive surgery for gallbladder carcinoma...
  26. ncbi request reprint Advanced gallbladder carcinoma with biliobiliary fistula, resected by hepatopancreatoduodenectomy, in an aged patient
    N Iwahashi
    Department of Surgery, Tohkai Hospital, Nagoya, Japan
    J Hepatobiliary Pancreat Surg 8:287-90. 2001
    ..We discuss biliobiliary fistula associated with gallbladder carcinomas and the use of hepatopancreatoduodenectomy for advanced biliary cancer in aged patients...
  27. ncbi request reprint Bilirubin impairs bactericidal activity of neutrophils through an antioxidant mechanism in vitro
    T Arai
    First Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    J Surg Res 96:107-13. 2001
    ..To address this, we evaluated the effects of bilirubin on the bactericidal activity of ROS or of neutrophils in vitro...
  28. ncbi request reprint Retrograde portography of the right caudate lobe via the middle hepatic vein
    J Kamiya
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, 466 8550 Nagoya, Japan
    Surg Radiol Anat 26:24-7. 2004
    ..No complications were encountered. Retrograde portograms of the P1r may provide valuable information not previously available to surgeons operating on the caudate lobe...
  29. ncbi request reprint [Surgical treatment for hilar cholangiocarcinoma]
    Toshiyuki Arai
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine
    Nihon Rinsho 64:476-8. 2006
  30. doi request reprint Value of indocyanine green clearance of the future liver remnant in predicting outcome after resection for biliary cancer
    Y Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Br J Surg 97:1260-8. 2010
    ....
  31. ncbi request reprint Hepatocyte morphology and kinetics after portal vein embolization
    K Komori
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Br J Surg 93:745-51. 2006
    ..The aim of this study was to clarify hepatocyte morphology and kinetics after PVE...
  32. ncbi request reprint An experimental study of selective intrahepatic biliary ablation with ethanol
    T Kyokane
    First Department of Surgery, Nagoya University School of Medicine, 65 Tsurumai Cho, Syowa ku, Nagoya, 466 8550, Japan
    J Surg Res 96:188-96. 2001
    ..Few attempts have been made to investigate the feasibility of selective intrahepatic biliary ablation with absolute ethanol...
  33. ncbi request reprint Left hepatic trisegmentectomy with right hepatic vein resection after right hepatic vein embolization
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Surgery 133:580-2. 2003
  34. ncbi request reprint Evaluation of hepatic interleukin-6 secretion following portal vein ligation using a minimal surgical stress model
    Satoshi Kobayashi
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, JST, Nagoya 466 8550, Japan
    J Surg Res 135:27-33. 2006
    ..We developed a nonstress PVL model, which performs the ligation after surgical stress is subsided, and evaluated the hepatic IL-6 production at early phase of PVL...
  35. doi request reprint Proposal to modify the International Union Against Cancer staging system for perihilar cholangiocarcinomas
    T Ebata
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Br J Surg 101:79-88. 2014
    ..The International Union Against Cancer (UICC) staging system for perihilar cholangiocarcinoma changed in 2009. The aim of this study was to validate and optimize the UICC system for these tumours...
  36. ncbi request reprint Different gastric emptying of solid and liquid meals after pylorus-preserving pancreatoduodenectomy
    I Kobayashi
    First Department of Surgery, Nagoya University School of Medicine, Japan
    Br J Surg 85:927-30. 1998
    ..Changes in gastric emptying were investigated in patients undergoing PPPD for periampullary malignancy...
  37. ncbi request reprint CLCP1 interacts with semaphorin 4B and regulates motility of lung cancer cells
    H Nagai
    Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Oncogene 26:4025-31. 2007
    ..Although the physiological role of the interaction between CLCP1 and SEMA4B remains to be investigated, this novel gene may become a target of therapy to inhibit metastasis of lung cancers...
  38. ncbi request reprint Mechanisms of hepatic regeneration following portal vein embolization and partial hepatectomy: a review
    Y Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    World J Surg 31:367-74. 2007
    ....
  39. ncbi request reprint [Combined portal vein and liver resection for biliary cancer]
    M Nagino
    Division of Surgical Oncology, Department of Surgery Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nippon Geka Gakkai Zasshi 102:815-9. 2001
    ..These data suggest that portal vein resection has survival benefit for patients with cholangiocarcinoma. However, the indications for this procedure in gallbladder cancer should be reevaluated...
  40. ncbi request reprint Anomaly of the portal vein with an anomalous hepatic vein--the first case report
    K Hiramatsu
    First Department of Surgery, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
    Hepatogastroenterology 48:1142-4. 2001
    ..A limited excision of the involved liver was performed safely with the help of the preoperative definition of the abnormal liver anatomy...
  41. ncbi request reprint Biliary mucosal bridges
    H Miyake
    Division of Surgical Oncology, Dept of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Endoscopy 34:751. 2002
  42. doi request reprint 15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis
    Katsutaka Watanabe
    Dept of Surgery, Nagoya Univ Graduate School of Medicine, Showa Ku, Japan
    Am J Physiol Gastrointest Liver Physiol 298:G410-8. 2010
    ..These results clearly demonstrate that 15D-PGJ(2) inhibits the inflammatory response and endothelial cell damage seen in acute obstructive cholangitis and could contribute to improve the outcome of this pathology...
  43. ncbi request reprint Does estrogen contribute to the hepatic regeneration following portal branch ligation in rats?
    Toru Kawai
    Division of Surgical Oncology, Dept of Surgery, Nagoya Univ Graduate School of Medicine, Nagoya, Japan
    Am J Physiol Gastrointest Liver Physiol 292:G582-9. 2007
    ....
  44. pmc Hepatectomy with portal vein resection for hilar cholangiocarcinoma: audit of 52 consecutive cases
    Tomoki Ebata
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 238:720-7. 2003
    ..To better determine the role of portal vein resection and its effect on survival, as well as to appreciate the impact of portal vein invasion on prognosis in hilar cholangiocarcinoma...
  45. ncbi request reprint Recent advances in the treatment of hilar cholangiocarcinoma: portal vein embolization
    Yukihiro Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, 466 8550, Japan
    J Hepatobiliary Pancreat Surg 14:447-54. 2007
    ..We also describe our PVE procedure, which has been established from our experience of more than 240 cases of biliary cancer. Furthermore, the drawbacks of PVE, which may reduce the pool of candidates for surgery, are also discussed...
  46. doi request reprint Value of multidetector row CT in the assessment of longitudinal extension of cholangiocarcinoma: correlation between MDCT and microscopic findings
    Yoshiki Senda
    Department of Surgery, Division of Surgical Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    World J Surg 33:1459-67. 2009
    ..They have not focused on CT attenuation of a tumor and actual tumor extent along the bile ducts. We designed the present study to analyze attenuation...
  47. ncbi request reprint Aggressive surgery for stage IV gallbladder carcinoma; what are the contraindications?
    Hideki Nishio
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    J Hepatobiliary Pancreat Surg 14:351-7. 2007
    ..Advanced gallbladder carcinoma with paraaortic lymph node metastasis or distant metastasis is normally considered a contraindication for surgery. Our latest analyses suggest otherwise...
  48. ncbi request reprint Mechanism of impaired hepatic regeneration in cholestatic liver
    Yukihiro Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    J Hepatobiliary Pancreat Surg 14:159-66. 2007
    ..This review article summarizes the current understanding of the mechanism of hepatic regeneration, with particular emphasis on that in the cholestatic liver...
  49. ncbi request reprint Hepatectomy for colorectal liver metastases with macroscopic intrabiliary tumor growth
    Teiichi Sugiura
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    World J Surg 30:1902-8. 2006
    ..We set out to clarify the clinicopathologic characteristics of colorectal liver metastases with macroscopic intrabiliary tumor growth and to determine optimal surgical management...
  50. doi request reprint A left hepatectomy and caudate lobectomy combined resection of the ventral segment of the right anterior sector for hilar cholangiocarcinoma--the efficacy of PVE (portal vein embolization) in identifying the hepatic subsegment: report of a case
    Tsuyoshi Igami
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Surg Today 39:628-32. 2009
    ..The planned surgery was performed safely. This case demonstrates that the utilization of PVE is useful for a difficult and intricate hepatectomy, which requires an accurate identification of a hepatic subsegment...
  51. ncbi request reprint Portal and mesenteric vein thrombosis after portal vein embolization in a patient with protein S deficiency
    Masayuki Ohkubo
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, 466 8550, Nagoya, Japan
    J Hepatobiliary Pancreat Surg 11:338-41. 2004
    ..It may be better to determine the concentrations of such coagulation regulators prior to portal vein embolization...
  52. ncbi request reprint [Benefit of percutaneous transhepatic portal vein embolization for extended hepatectomy]
    Satoshi Kobayashi
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nihon Geka Gakkai Zasshi 105:354-8. 2004
    ..3% to 23.8% and from 21.9% to 9.5%, respectively. The technique of PTPE has contributed to an improved survival rate for patients with severely advanced biliary cancer...
  53. doi request reprint Value of Multidetector-row Computed Tomography in Diagnosis of Portal Vein Invasion by Perihilar Cholangiocarcinoma
    Teiichi Sugiura
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    World J Surg 32:1478-84. 2008
    ..We evaluated how well MDCT could identify cancer invasion of the portal bifurcation by perihilar cholangiocarcinoma...
  54. ncbi request reprint Biliary bile acid concentration is a simple and reliable indicator for liver function after hepatobiliary resection for biliary cancer
    Yasuhiro Kurumiya
    Division of Surgical Oncology, Department of Surgery, and the Laboratory of Cancer Cell Biology, Research Institute for Disease Mechanism and Control, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Surgery 133:512-20. 2003
    ..The aim of this prospective study was to examine whether biliary bile acids could be an indicator for postoperative liver function...
  55. pmc The value of bile replacement during external biliary drainage: an analysis of intestinal permeability, integrity, and microflora
    Satoshi Kamiya
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 239:510-7. 2004
    ..To investigate the effect of bile replacement following percutaneous transhepatic biliary drainage, ie, external drainage, on intestinal permeability, integrity, and microflora in a clinical setting...
  56. ncbi request reprint Repeat hepatectomy for colonic liver metastasis presenting intrabiliary growth--application of percutaneous transhepatic portal vein embolization for impaired liver
    Kazuhiro Hiramatsu
    Division of Surgical Oncology, Department of Surgery Nagoya University Graduate School of Medicine, Nagoya, Japan
    Hepatogastroenterology 54:1554-6. 2007
    ..The patient survived for 4 years and 5 months postoperatively and died of other causes. An aggressive surgical strategy and PTPE provided significant palliation in this selected patient...
  57. doi request reprint A rare surgical case of multiple liver resections for recurrent liver metastases from pancreatic gastrinoma: liver and vena cava resection
    Silvia Pachera
    Division of Surgical Oncology, Department of Surgery, Graduate School of Medicine, University of Nagoya, 65 Tsurumai Cho, Showa Ku, Nagoya, Aichi, 466 8550, Japan
    J Hepatobiliary Pancreat Surg 16:692-8. 2009
    ..The patient described here is still alive, free of disease and leading a normal life, 20 years after the initial diagnosis and 3 years after the last surgery...
  58. doi request reprint Real-time monitoring of liver damage during experimental ischaemia-reperfusion using a nitric oxide sensor
    A Nakagawa
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Br J Surg 99:1120-8. 2012
    ..The aim of this study was to demonstrate real-time changes in intrahepatic NO concentration during IR and to correlate potential hepatic NO production with liver damage using a selective NO sensor...
  59. doi request reprint Rectal duplication cyst successfully treated by laparoscopic total mesorectal excision using the prolapsing technique
    K Akahane
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian J Endosc Surg 4:174-7. 2011
    ..Pathologically, the cystic lesion was diagnosed as a rectal duplication cyst. This is the first report of a rectal duplication cyst successfully treated by laparoscopic total mesorectal excision...
  60. doi request reprint Prospective study of biliary cytology in suspected perihilar cholangiocarcinoma
    M Hattori
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Br J Surg 98:704-9. 2011
    ..The diagnostic value of biliary cytology for hilar bile duct stricture is uncertain. This study prospectively examined three methods for the evaluation of biliary cytology in a consecutive group of patients...
  61. ncbi request reprint Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92
    H Matsubara
    Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Oncogene 26:6099-105. 2007
    ..Taken together, the present findings contribute towards better understanding of the oncogenic roles of miR-17-92, which might ultimately lead to the future translation into clinical applications...
  62. ncbi request reprint Pancreatic and duodenal invasion in distal bile duct cancer: paradox in the tumor classification of the American Joint Committee on Cancer
    Tomoki Ebata
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    World J Surg 31:2008-15. 2007
    ..The aim of this study was to assess whether this T classification is rational from the viewpoint of prognostic power...
  63. ncbi request reprint [Pathologically complete response of multiple liver metastases from rectal cancer treated with mFOLFOX6 plus bevacizumab]
    Masaya Inoue
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Japan
    Nihon Shokakibyo Gakkai Zasshi 107:760-7. 2010
    ..Regimens containing bevacizumab may result in good tumor response. Surgical resection is crucial for proof of pathologically complete response...
  64. ncbi request reprint A case of intracystic papillary carcinoma accompanying widespread ductal carcinoma in situ
    Takeshi Amemiya
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Breast Cancer 14:312-6. 2007
    ..Careful selection of operative procedure is needed after localized non-invasive IPC or IPC associated with DCIS around the main tumor or invasive carcinoma is diagnosed...
  65. doi request reprint Perineural invasion is a prognostic factor in intrahepatic cholangiocarcinoma
    Kazuhisa Shirai
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, 466 8550, Japan
    World J Surg 32:2395-402. 2008
    ..The aim of this study was to evaluate the clinical significance of perineural invasion in ICC...
  66. doi request reprint Advances in the treatment of pancreatic cancer: limitations of surgery and evaluation of new therapeutic strategies
    Yukihiro Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Surg Today 39:466-75. 2009
    ..Although the benefits of radiotherapy alone are limited, the results of chemotherapy are promising. Other newly evolving molecular targeting drugs may also improve the treatment outcomes of pancreatic cancer...
  67. doi request reprint Radiologic-pathologic conferences of the Nagoya University Hospital: centrally necrotizing carcinoma of the breast
    Koji Oda
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    AJR Am J Roentgenol 190:W237-9. 2008
  68. doi request reprint Sex dimorphism in the outcome of preoperative right portal vein embolization
    Yukihiro Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Arch Surg 143:254-9; discussion 259. 2008
    ..We analyzed the effects of patient sex on the outcome of right PVE followed by major hepatectomy...
  69. ncbi request reprint Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury
    Yukihiro Yokoyama
    Department of Surgery, Division of Surgical Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Shock 29:688-91. 2008
    ..These results indicated that despite a highly increased production in the liver, TXA2 is not directly related to the hepatic injury in BDL rats...
  70. ncbi request reprint Surgical approach to bismuth Type I and II hilar cholangiocarcinomas: audit of 54 consecutive cases
    Takashi Ikeyama
    Division of Surgical Oncology, Department of Surgery Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 246:1052-7. 2007
    ..To clarify the optimal surgical strategy for Bismuth type I and II hilar cholangiocarcinomas...
  71. ncbi request reprint Nek2 as an effective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma
    Toshio Kokuryo
    Division of Surgical Oncology, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Cancer Res 67:9637-42. 2007
    ..Taken together, our data indicate a pivotal role of Nek2 in tumorigenic growth of cholangiocarcinoma...
  72. ncbi request reprint Infraportal bile duct of the caudate lobe: a troublesome anatomic variation in right-sided hepatectomy for perihilar cholangiocarcinoma
    Teiichi Sugiura
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 246:794-8. 2007
    ..We present our experiences with infraportal bile duct of the caudate lobe (B1) and discuss surgical implications of this rare variation...
  73. ncbi request reprint Treatment of colorectal liver metastasis with biliary and portal vein tumor thrombi by hepatopancreatoduodenectomy
    Teiichi Sugiura
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    J Hepatobiliary Pancreat Surg 13:256-9. 2006
    ..The inferior vena cava, right kidney, and renal vein could be detached from the tumor. The patient has enjoyed an active life without recurrence for 2 years since the operation...
  74. ncbi request reprint Intense PET signal in the degenerative necrosis superimposed on chronic pancreatitis
    Yukihiro Yokoyama
    Division of Surgical Oncology, Department of Surgery, University of Nagoya Graduate School of Medicine, Nagoya, Japan
    Pancreas 31:192-4. 2005
    ..Repetitive PET examination is recommended for the accurate diagnosis...
  75. ncbi request reprint Right gastroepiploic artery occlusion test for resection of recurrent lesion after esophageal reconstruction using a gastric tube
    Eiji Hayashi
    Department of Surgery, Division of Surgical Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Am J Surg 187:446-9. 2004
    ....
  76. ncbi request reprint Clinicopathologic features of re-resected cases of intraductal papillary mucinous neoplasms (IPMNs)
    Yukihiro Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Japan
    Surgery 142:136-42. 2007
    ..We analyzed the clinical characteristics and patterns of recurrence of intraductal papillary mucinous neoplasms (IPMNs) from 100 consecutive surgical cases...
  77. ncbi request reprint Simultaneous segmental obstruction of bile duct and portal vein markedly changes a population of biliary and hepatic cells in human liver
    Takanori Kyokane
    First Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Syowa ku, 466 8550 Nagoya, Japan
    Langenbecks Arch Surg 388:270-5. 2003
    ..No studies have investigated histologic changes caused by simultaneous segmental obstruction of the bile duct and portal vein in human liver...
  78. ncbi request reprint Cystic duct carcinoma: a proposal for a new "working definition"
    Ilgin Ozden
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumaicho Showaku, Nagoya 466 8550, Japan
    Langenbecks Arch Surg 387:337-42. 2003
    ..We propose new "working definition": a gallbladder tumor, the center of which is located in the cystic duct...
  79. ncbi request reprint A study of the subvesical bile duct (duct of Luschka) in resected liver specimens
    Kenju Ko
    Department of Surgery, Division of Surgical Oncology, Nagoya University Graduate School of Medicine, 65 Tsurumai cho Showa ku, Nagoya, 466 8550, Japan
    World J Surg 30:1316-20. 2006
    ..Injury to the duct of Luschka is associated with biliary fistula from the gallbladder bed after cholecystectomy. However, few studies have reported on the detailed anatomy. We elucidated the anatomy and frequency of the duct of Luschka..
  80. ncbi request reprint Surgical treatment for colorectal liver metastases involving the paracaval portion of the caudate lobe
    Hideo Yamamoto
    Department of Surgery, Tohkai Hospital, 1 1 1 Chiyodabashi Chikusa ku, Nagoya 464, Japan
    Surgery 137:26-32. 2005
    ..We reevaluated resected cases of colorectal liver metastases involving S1r to confirm the significance of aggressive surgical treatments...
  81. ncbi request reprint [Dose "extended" surgery for pancreatic head adenocarcinoma have survival impact?]
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nihon Geka Gakkai Zasshi 107:173-6. 2006
    ..We should therefore conclude that extended surgery does not improve survival for patients with pancreas head adenocarcinoma...
  82. pmc Immunohistochemically demonstrated lymph node micrometastasis and prognosis in patients with otherwise node-negative hilar cholangiocarcinoma
    Yuichiro Tojima
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Surg 237:201-7. 2003
    ..To investigate whether immunohistochemically demonstrated lymph node micrometastasis has prognostic significance in patients with histologically node-negative (pN0) hilar cholangiocarcinoma...
  83. ncbi request reprint [Hepatic failure following resection of cholestatic liver]
    Toshiyuki Arai
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nihon Geka Gakkai Zasshi 105:664-8. 2004
    ....
  84. ncbi request reprint Clinicoanatomical study on the infraportal bile ducts of segment 3
    Ilgin Ozden
    Department of Surgery, Division of Surgical Oncology, Nagoya University Graduate School of Medicine, 65 Tsurumaicho Showaku, Nagoya 466 8550, Japan
    World J Surg 26:1441-5. 2002
    ..Separate biliary reconstruction for an infraportal branch is mandatory in an extended right hepatectomy for biliary tract cancer and may be necessary in liver transplantation with segments 2+3 grafting...
  85. ncbi request reprint Mechanical stress-dependent secretion of interleukin 6 by endothelial cells after portal vein embolization: clinical and experimental studies
    Masami Kawai
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Japan
    J Hepatol 37:240-6. 2002
    ..Changes in portal hemodynamics after portal vein embolization (PVE) may contribute to IL-6 release, leading to regeneration of non-embolized lobe...
  86. ncbi request reprint Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uniaxial continuous stretch
    Akitoshi Sasamoto
    Department of Physiology, Nagoya Univ Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Am J Physiol Cell Physiol 288:C1012-22. 2005
    ..Another crucial factor, [Ca(2+)](i) increase, may at least be required to activate PKC needed for NF-kappaB activation...
  87. ncbi request reprint Percutaneous ethanol injection via an artificially induced right hydrothorax for hepatocellular carcinoma in the hepatic dome
    Akimichi Kume
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Cardiovasc Intervent Radiol 26:543-9. 2003
    ..Induction of a right hydrothorax is feasible and safe. The hydrothorax enables US visualization of the entire hepatic dome and permits US-guided PEI for HCC in the hepatic dome that otherwise would not be possible...
  88. doi request reprint Randomized clinical trial of the effect of perioperative synbiotics versus no synbiotics on bacterial translocation after oesophagectomy
    Y Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Br J Surg 101:189-99. 2014
    ..This study investigated the effect of perioperative synbiotic administration on the incidence of bacterial translocation to mesenteric lymph nodes (MLNs) and the occurrence of postoperative bacteraemia...
  89. ncbi request reprint Aggressive preoperative management and extended surgery for inflammatory pseudotumor involving the hepatic hilum in a child
    K Kaneko
    Department of Pediatric Surgery, Nagoya University School of Medicine, Nagoya, Japan
    Surgery 129:757-60. 2001
    ..3)..
  90. doi request reprint Silencing of Tousled-like kinase 1 sensitizes cholangiocarcinoma cells to cisplatin-induced apoptosis
    Yuichi Takayama
    Division of Surgical Oncology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Japan
    Cancer Lett 296:27-34. 2010
    ..Immunofluorescence analysis of gammaH2AX foci showed that silencing of TLK1 enhanced DNA damage induced by cisplatin treatment. Our results suggest that TLK1 plays a pivotal role for the repair of cisplatin-induced DNA damage...
  91. doi request reprint Inchinkoto, an herbal medicine, exerts beneficial effects in the rat liver under stress with hepatic ischemia-reperfusion and subsequent hepatectomy
    Kiyotaka Kawai
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Ann Surg 251:692-700. 2010
    ..To investigate the beneficial effects of inchinkoto (ICKT) in the liver after 70% hepatectomy following ischemia reperfusion...
  92. ncbi request reprint Diagnosis and treatment of inferior vena caval invasion by hepatic cancer
    Yoshito Okada
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsuramai cho, Showa Ku, Nagoya, 466 8550, Japan
    World J Surg 27:689-94. 2003
    ..This strategy is important to avoid unnecessary resection of the IVC, use of a prosthetic graft, or ex vivo hepatectomy...
  93. doi request reprint Estrogen promotes hepatic regeneration via activating serotonin signal
    Tomomi Kitagawa
    Department of Surgery, Division of Surgical Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Shock 31:615-20. 2009
    ..Our results also indicated that estrogen is at least partly related to the activation of serotonin system, which is also important in the process of liver regeneration...
  94. ncbi request reprint [Surgical strategy for hilar cholangiocarcinoma: comparison between Japan and Europe]
    Masato Nagino
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nihon Geka Gakkai Zasshi 109:349-54. 2008
    ..Japanese surgeons have taken the lead in biliary cancer surgery and should continue to make efforts to improve patient survival in this intractable disease...
  95. doi request reprint Treatment of pancreatic fistula after pancreatoduodenectomy using a hand-made T-tube
    Tsuyoshi Igami
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    J Hepatobiliary Pancreat Surg 16:661-7. 2009
    ..To describe a technique for the treatment of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD) using a hand-made T-tube...
  96. ncbi request reprint Complete resection of hepatocellular carcinoma with direct invasion to the stomach remnant
    Kimihito Fujii
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumaicho, Showa Ku, Nagoya 466 8550, Japan
    J Hepatobiliary Pancreat Surg 11:441-4. 2004
    ..Direct invasion of HCC into the gastrointestinal tract is rarely encountered. Here we report a case of HCC that invaded the stomach remnant and present a review of the literature...
  97. ncbi request reprint Synbiotics reduce postoperative infectious complications: a randomized controlled trial in biliary cancer patients undergoing hepatectomy
    Hidetoshi Kanazawa
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Langenbecks Arch Surg 390:104-13. 2005
    ..The aim of this study was to investigate the effect of synbiotics on intestinal integrity and microflora, as well as on surgical outcome, in patients undergoing high-risk hepatectomy...
  98. doi request reprint Clinicopathologic study of cholangiocarcinoma with superficial spread
    Tsuyoshi Igami
    Department of Surgery, Nagoya University Graduate School of Medicine, Japan
    Ann Surg 249:296-302. 2009
    ..To review our experience with cholangiocarcinoma with superficial spread, to clarify its clinical features, and to discuss treatment strategies...
  99. ncbi request reprint Right hepatopancreatoduodenectomy: improvements over 23 years to attain acceptability
    Tomoki Ebata
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    J Hepatobiliary Pancreat Surg 14:131-5. 2007
    ..We retrospectively analyzed our progress over 23 years in making this operation safer...
  100. ncbi request reprint Biphasic activation of liver regeneration-associated signals in an early stage after portal vein branch ligation
    Shinya Yokoyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Biochem Biophys Res Commun 349:732-9. 2006
    ....
  101. doi request reprint Follicular lymphoma of the extrahepatic bile duct mimicking cholangiocarcinoma
    Gen Sugawara
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    J Hepatobiliary Pancreat Surg 15:196-9. 2008
    ..Postoperative follow-up of more than 1 year has been completely uneventful, without any symptoms or signs of disease recurrence. This is the second case report of follicular lymphoma of the extrahepatic bile duct...