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Genomes and Genes | Naoyoshi MoriSummaryAffiliation: Nagoya University Country: Japan Publications
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Publications
TIA-1 expression in hairy cell leukemiaNaoyoshi Mori
Department of Pathology of Biological Response, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
Mod Pathol 17:840-6. 2004..Moreover, TIA-1 reactivity in lymphomas does not necessarily indicate a T- or NK-cell derivation...- Interleukin-8 gene polymorphism associated with susceptibility to non-cardia gastric carcinoma with microsatellite instabilityKennosuke Shirai
Division of Gastroenterology, Department of Therapeutic Medicine, Nagoya University School of Medicine, Nagoya, Japan
J Gastroenterol Hepatol 21:1129-35. 2006..Recently, cytokine polymorphisms have been reported to affect the development of non-cardia GC. The objective of this study was to elucidate the relationship between cytokine polymorphisms and MSI phenotypes... - Promoter hypermethylation of the DNA-repair gene O6-methylguanine-DNA methyltransferase and p53 mutation in diffuse large B-cell lymphomaJunji Hiraga
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Int J Hematol 84:248-55. 2006..88, and P = .31, respectively). MGMT promoter hypermethylation and p53 mutation are useful prognostic markers in DLBCL. The impact of MGMT inactivation on p53 mutation in DLBCL is unclear... - Severity of atrophic gastritis related to antiparietal cell antibody and gastric carcinogenesis, including p53 mutationsAyumu Taguchi
Division of Gastroenterology, Department of Therapeutic Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
J Gastroenterol Hepatol 21:545-51. 2006..Severe atrophic gastritis is associated with susceptibility to gastric carcinoma, especially the intestinal subtype, and p53 mutations... - c-Maf expression in angioimmunoblastic T-cell lymphomaYoshiko Idate Murakami
Department of Pathology of Biological Response, Nagoya University Graduate School of Medicine, Tsurumai cho 65, Showa Ku, Japan
Am J Surg Pathol 31:1695-702. 2007..016, chi test). These findings strongly suggest that CD4-positive neoplastic T cells in AILT show c-Maf expression and provide new insight into the pathogenesis of AILT suggesting c-Maf to be a useful diagnostic marker for AILT... - Development-dependent expression of cyclin D3 in precursor T-cell lymphoblastic leukemia/lymphomaEiichi Sasaki
Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan
Pathol Int 57:53-9. 2007..Taken together with the crucial and non-redundant role in T-cell development in mice, this molecule is suggested to play an important role in human T-cell development... - Aggressive Lennert's lymphoma: report of three cases in comparison to non-aggressive Lennert's lymphomaAtsuko Kitamura
Department of Pathology of Biological Response, Nagoya University Graduate School of Medicine, Tsurumai, Showa, Japan
Pathol Int 55:626-31. 2005..In conclusion it was found that a subset of Lennert's lymphoma cases share common features with high-grade cytotoxic T-cell lymphoma, indicating that Lennert's lymphoma may be part of the spectrum of cytotoxic T-cell lymphoma... - Breast-specific expression of MGB1/mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancersEiichi Sasaki
Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Aichi, Japan
Mod Pathol 20:208-14. 2007..Secondly, as primary lung adenocarcinomas may express estrogen receptors, MGB1 expression provides further discrimination of the origin of breast cancers... 
XCR1 expression and biased VH gene usage are distinct features of diffuse large B-cell lymphoma initially manifesting in the bone marrowYoriko Yamashita
Dept of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Japan
Am J Clin Pathol 135:556-64. 2011..05), which was confirmed by quantitative reverse transcriptase-PCR and immunohistochemical analysis. Expression of the chemokine receptor XCR1 and frequent usage of autoreactive V(H) genes seem to be distinct characteristics of BM-DLBCL...- Nestin expression as a new marker in malignant peripheral nerve sheath tumorsSatoko Shimada
Departments of Pathology of Biological Response, Nagoya University Graduate School of Medicine, Nagoya, Japan
Pathol Int 57:60-7. 2007..Nestin is more sensitive for MPNST than other neural markers and immunostains for nestin in combination with other markers could be useful in the diagnosis of MPNST... - Loss of O6-methylguanine-DNA methyltransferase protein expression is a favorable prognostic marker in diffuse large B-cell lymphomaToshihito Ohno
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Int J Hematol 83:341-7. 2006..09; P = .0258). Lack of MGMT protein expression is associated with aberrant promoter DNA methylation and appears to be a useful marker for predicting the survival of DLBCL patients... - Immortalization of Epstein-Barr virus-negative human B lymphocytes with minimal chromosomal instabilityYoriko Yamashita
Department of Pathology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Pathol Int 56:659-67. 2006..Furthermore, using this system, it is possible to analyze the role of individual genes in human B lymphocyte immortalization without the influence of a pre-existing Epstein-Barr virus genome... - Distribution of nestin and other stem cell-related molecules in developing and diseased human spinal cordAyako Sakakibara
Department of Pathology, Nagoya University School of Medicine, Nagoya, Japan
Pathol Int 57:358-68. 2007..These cells, however, appear in response to disease conditions, especially tumor involvement... - Sustained remission after rituximab-containing chemotherapy for intravascular large B-cell lymphomaKazuyuki Shimada
Department of Hematology, Ogaki Municipal Hospital, Gifu, Japan
J Clin Exp Hematop 48:25-8. 2008..She has remained in complete remission for over 3 years after diagnosis. This report suggests that rituximab-containing regimens could be safe and effective for elderly patients with IVL... - Long-term follow-up in patients with Pendred syndrome: vestibular, auditory and other phenotypesMakoto Sugiura
Department of Otorhinolaryngology, Nagoya University School of Medicine, 466 8550 Nagoya, Japan
Eur Arch Otorhinolaryngol 262:737-43. 2005..Whether environmental factors or a subtype of the Pds mutation H723R are related to the long-term outcome for these patients must be clarified... - The immunohistochemical analysis of pendrin in the mouse inner earTakahiko Yoshino
Department of Otorhinolaryngology, University of Nagoya, 65, Tsurumai cho, Showa Ku, Nagoya 4668550, Japan
Hear Res 195:9-16. 2004..Our results are key to defining the role of pendrin in inner ear development and elucidating the pathogenic mechanisms underlying deafness in PS... - Role for RFX transcription factors in non-neuronal cell-specific inactivation of the microtubule-associated protein MAP1A promoterAtsuo Nakayama
Department of Pathology, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Aichi, Japan
J Biol Chem 278:233-40. 2003..The cell type-specific down-regulation, however, does not depend simply on which RFX interacts with the elements, but seems to depend on underlying profound mechanisms... - Frequent expression of CD30 antigen in the primary gastric non-B, non-Hodgkin lymphomasSachiko Iwamizu-Watanabe
Department of Pathology of Molecular Diagnosis and Biological Response, Nagoya University Graduate School of Medicine, Nagoya, Japan
Pathol Int 54:503-9. 2004..We consider that some of the cases in the present study may be derived from cytotoxic T cells, similar to systemic and cutaneous ALCL, the majority of which exhibit TIA-1... 
Sphingosine 1-phosphate potentiates human lung fibroblast chemotaxis through the S1P2 receptorMitsu Hashimoto
Department of Pathology, Nagoya University School of Medicine, Nagoya, Japan
Am J Respir Cell Mol Biol 39:356-63. 2008..The pathways by which S1P mediates this effect, therefore, represent a potential therapeutic target to affect tissue repair and remodeling...- Phenotypic composition of salivary gland tumors: an application of principal [corrected] component analysis to tissue microarray dataHideto Iwafuchi
Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan
Mod Pathol 17:803-10. 2004..Individual subtypes were clustered among the three dimensions of the components. This implies that salivary gland tumors may be well characterized by using only three components... - Quantitative analysis of herpesvirus load in the lymph nodes of patients with histiocytic necrotizing lymphadenitis using a real-time PCR assayNagako Maeda
Department of Pathology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Diagn Mol Pathol 15:49-55. 2006.... - Diffuse large B-cell lymphoma initially manifesting in the bone marrowDai Kajiura
Department of Pathology of Biological Response, Nagoya University Graduate School of Medicine, Nagoya, Japan
Am J Clin Pathol 127:762-9. 2007.... - Mucin biosynthesis: molecular cloning and expression of mouse mucus-type core 2 beta1,6 N-acetylglucosaminyltransferaseMitsuyoshi Hashimoto
Department of Pathology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Glycobiology 17:994-1006. 2007..This report provides the basis for further characterization of the regulation of mC2GnT-M gene expression and the biological functions of this gene... - Rheumatoid arthritis with diffuse pulmonary rheumatoid nodulesAtsuko Kitamura
Department of Pathology of Biological Response, Nagoya University Graduate School of Medicine, Nagoya, Japan
Pathol Int 54:798-802. 2004..Findings with this patient indicate that, in patients with rheumatoid arthritis, clinical interstitial pneumonitis confirmed radiologically does not exclude the existence of rheumatoid lung nodules... - Malignant mesothelioma of the tunica vaginalis testis: a case with a predominant sarcomatous componentSatoko Shimada
Department of Pathology of Biological Response, Nagoya University Graduate School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya, Aichi 466 8550, Japan
Pathol Int 54:930-4. 2004..In general, a sarcomatous component predicts poor prognosis and our case does, in fact, deteriorate over time. Our case suggests that despite its low incidence, MM must be considered when a case is diagnosed as hydrocele testicle... - The association between tumour necrosis factor-alpha gene polymorphism and the susceptibility to rugal hyperplastic gastritis and gastric carcinomaItaru Ohyama
Department of Therapeutic Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
Eur J Gastroenterol Hepatol 16:693-700. 2004..The aim of this study was to clarify the association of tumour necrosis factor-alpha (TNFA) gene polymorphism with susceptibility to hyper-rugosity. We also examined the association of TNFA polymorphism with gastric carcinoma... - Interferon-gamma regulates apoptosis by releasing soluble tumor necrosis factor receptors in a gastric epithelial cell lineShimako Furuta
Second Department of Internal Medicine, Nagoya University School of Medicine, Showa Ku, Japan
J Gastroenterol Hepatol 17:1283-90. 2002..We attempted to clarify the apoptotic activity and the synergistic effect of IFN-gamma and TNF on the gastric epithelial cell, and whether IFN-gamma relates to soluble TNF receptors (sTNF-R) release from the gastric epithelial cell... - Aberrant DNA methylation of p57(KIP2) gene in the promoter region in lymphoid malignancies of B-cell phenotypeYinghua Li
First Department of Internal Medicine, and the First Department of Pathology, Nagoya University School of Medicine, Nagoya, Japan
Blood 100:2572-7. 2002..0%), but methylation was infrequent in myelodysplastic syndrome and adult T-cell leukemia (3.0% and 2.0%, respectively). These findings directly indicate that the profile of the p57(KIP2) gene corresponds to that of a TSG... - Nodal CD8 positive cytotoxic T-cell lymphoma: a distinct clinicopathological entityHarumi Y Mukai
Division of Hematology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan
Mod Pathol 15:1131-9. 2002..Our results suggest that these nodal cytotoxic T-cell lymphomas originated from activated cytotoxic T-cells and were highly accompanied with DIC or HPS... - Cytotoxic T-cell lymphoma arising in Behçet diseaseYukitaka Katsura
Division of Hematology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
Int J Hematol 77:282-5. 2003..We have summarized the published case reports of malignant lymphoma arising in BD. To our knowledge, this case report is the first to describe cytotoxic T-cell lymphoma arising in Behçet disease... - Epstein-Barr virus-positive Hodgkin/Reed-Sternberg-like B cell in non-hodgkin lymphoma: nucleotide sequence of the amplified immunoglobulin heavy-chain variable region gene by the single-cell polymerase chain reaction techniqueNaoya Nakamura
Department of Pathology, Fukushima Medical University School of Medicine, Fukushima shi, Japan
Diagn Mol Pathol 11:83-9. 2002..The HRS-like B cells may appear because of active EBV infection in a patient who is immunosuppressed from the primary lymphoma... - Rapidly progressive Lennert's lymphoma terminating in fulminant hepatic failureHiroshi Kojima
Division of Hematology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki 305 8575, Japan
Leuk Lymphoma 44:1409-12. 2003..J. Surg. Pathol. 24 (2000) 1627]. It should be also emphasized that Lennert's lymphomas containing cytotoxic proteins may have a fulminant clinical course, which cannot be rescued by the conventional chemotherapy... - Overexpression of c-Maf contributes to T-cell lymphoma in both mice and humanNaoki Morito
Department of Anatomy and Embryology, Biomolecular and Integrated Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba 305 8575, Japan
Cancer Res 66:812-9. 2006..These results suggest that c-Maf might cause a type of T-cell lymphoma in both mice and humans and that ARK5, in addition to cyclin D2 and integrin beta(7), might be downstream target genes of c-Maf leading to malignant transformation... - ALK+, CD30-, CD20- large B-cell lymphoma containing anaplastic lymphoma kinase (ALK) fused to clathrin heavy chain gene (CLTC)Norio Chikatsu
Department of Internal Medicine, Hitachi General Hospital, Hitachi, Ibaraki, USA
Mod Pathol 16:828-32. 2003..We consider that this case confirms the existence of ALK(+), CD30(-), CD20(-) large B-cell lymphomas proposed by Delsol et al. (16) and further provides relevant information regarding their clinicopathological features and cytogenetics... - Primary jejunal malignant melanoma first noticed because of the presence of parotid lymph node metastasisShigeruko Iijima
Department of Dermatology, Mmito Saiseikai General Hospital, Mito, Japan
J Am Acad Dermatol 49:319-23. 2003..We discuss why the tumor in our case was considered primary, and we review similar cases of primary melanoma of the small intestine... - Intracranial lesion of Erdheim-Chester diseaseSatoko Shimada
Hum Pathol 38:950-1. 2007 - Intravascular large B-cell lymphoma (IVLBCL): a clinicopathologic study of 96 cases with special reference to the immunophenotypic heterogeneity of CD5Takuhei Murase
Department of Internal Medicine, Nishio Municipal Hospital, 6 Kami awara, Kumamicho, Nishio, Aichi, and Department of Hematology, Mie University Graduate School of Medicine, Tsu, Japan
Blood 109:478-85. 2007..459), and thrombocytopenia less than 100x10(9)/L (P=.012, HR: 2.427) were independently unfavorable prognostic factors; CD5 positivity was not. Beyond immunophenotypic diversity, IVLBCL constitutes a unique group with aggressive behavior... - Simultaneous development of lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma--analyses of the clonal relatedness by sequencing CDR3 in immunoglobulin heavy chain genesSeiichi Shimizu
Division of Hematology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
Eur J Haematol 70:119-24. 2003..The data showed that LPL and DLBCL in the present patient originated from two independent clones... - Clinicopathological features and prognostic factors of Japanese patients with "peripheral T-cell lymphoma, unspecified" diagnosed according to the WHO classificationHiroshi Kojima
Division of Hematology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
Leuk Res 28:1287-92. 2004..6 and 25.0%, respectively. Performance status, serum LDH, and B symptom were significant prognostic factors. Survival of CD4-/CD8+ cases, corresponding to cytotoxic T-cell lymphoma, was significantly worse than that of CD4+/CD8-... - A common clonal origin of nodal marginal zone B-cell lymphoma and plasma cell myeloma demonstrating different immunophenotypes: a case report of composite lymphomaHajime Saito
Department of Hematology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
Diagn Mol Pathol 13:75-80. 2004..Sequence analysis of the IgH gene was a powerful tool for determination of clonal origin... - Immunohistochemical detection of CD79a expression in precursor T cell lymphoblastic lymphoma/leukaemiasMitsuyoshi Hashimoto
Pathology Section, Nagoya University Hospital, Japan
J Pathol 197:341-7. 2002..These results suggest that CD79a is expressed weakly and transiently in immature T-lineage cells... - Successful treatment of a patient with subcutaneous panniculitis-like T-cell lymphoma with high-dose chemotherapy and total body irradiationHarumi Y Mukai
Division of Hematology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
Eur J Haematol 70:413-6. 2003..Thereafter, he has been in remission for more than 2 yr. We consider that SPTCL with hemophagocytosis is an extremely aggressive disease, and high-dose chemotherapy and TBI should be included for the choice of the treatment...