Takaki Miyata

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. ncbi request reprint [Cytoskeleton and adhesion of the migratory neurons]
    Takaki Miyata
    Tanpakushitsu Kakusan Koso 51:721-6. 2006
  2. ncbi request reprint Asymmetric cell division during brain morphogenesis
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi 466 8550, Japan
    Prog Mol Subcell Biol 45:121-42. 2007
  3. ncbi request reprint Development of three-dimensional architecture of the neuroepithelium: role of pseudostratification and cellular 'community'
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi 466 8550, Japan
    Dev Growth Differ 50:S105-12. 2008
  4. ncbi request reprint [Cortical histogenesis captured by slice culture]
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showaku, Nagoya, 466 8550 Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 25:175-81. 2005
  5. ncbi request reprint Twisting of neocortical progenitor cells underlies a spring-like mechanism for daughter-cell migration
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Aichi 466 8550, Japan
    Curr Biol 17:146-51. 2007
  6. ncbi request reprint Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells
    Takaki Miyata
    Laboratory for Cell Culture Development, Brain Science Institute, RIKEN, Saitama 351 0198, Japan
    Development 131:3133-45. 2004
  7. pmc Morphology and mechanics of daughter cells "delaminating" from the ventricular zone of the developing neocortex
    Takaki Miyata
    Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Cell Adh Migr 1:99-101. 2007
  8. pmc Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Neural Dev 5:23. 2010
  9. ncbi request reprint Rac is involved in the interkinetic nuclear migration of cortical progenitor cells
    Sayaka Minobe
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Aichi, Japan
    Neurosci Res 63:294-301. 2009
  10. ncbi request reprint Differential expression of Pax6 and Ngn2 between pair-generated cortical neurons
    Ayano Kawaguchi
    Laboratory for Cell Culture Development, Brain Science Institute, RIKEN, Wako, Saitama, Japan
    J Neurosci Res 78:784-95. 2004

Collaborators

Detail Information

Publications35

  1. ncbi request reprint [Cytoskeleton and adhesion of the migratory neurons]
    Takaki Miyata
    Tanpakushitsu Kakusan Koso 51:721-6. 2006
  2. ncbi request reprint Asymmetric cell division during brain morphogenesis
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi 466 8550, Japan
    Prog Mol Subcell Biol 45:121-42. 2007
    ....
  3. ncbi request reprint Development of three-dimensional architecture of the neuroepithelium: role of pseudostratification and cellular 'community'
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi 466 8550, Japan
    Dev Growth Differ 50:S105-12. 2008
    ..In particular, we suggest that a systems biology approach to the NE/VZ as a cellular 'community' may be fruitful...
  4. ncbi request reprint [Cortical histogenesis captured by slice culture]
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showaku, Nagoya, 466 8550 Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 25:175-81. 2005
    ....
  5. ncbi request reprint Twisting of neocortical progenitor cells underlies a spring-like mechanism for daughter-cell migration
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Aichi 466 8550, Japan
    Curr Biol 17:146-51. 2007
    ..These results uncover a novel mechanism for cellular migration and provide valuable tools for the detailed study of the role of mechanical forces in 3D brain development...
  6. ncbi request reprint Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells
    Takaki Miyata
    Laboratory for Cell Culture Development, Brain Science Institute, RIKEN, Saitama 351 0198, Japan
    Development 131:3133-45. 2004
    ..The asymmetric P/P division may therefore contribute to efficient neuron/progenitor segregation required for CP initiation through cell cycle-dependent and lineage-restricted expression of Ngn2...
  7. pmc Morphology and mechanics of daughter cells "delaminating" from the ventricular zone of the developing neocortex
    Takaki Miyata
    Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Cell Adh Migr 1:99-101. 2007
    ..Thus, these contrasting movements of daughter cells suggest that differential pulling forces may act separately on their pial and ventricular processes as they delaminate from the telencephalic germinal zone...
  8. pmc Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Neural Dev 5:23. 2010
    ..Furthermore, it is not known what nascent Purkinje cells look like in vivo. When and how Purkinje cells start axonogenesis must also be elucidated...
  9. ncbi request reprint Rac is involved in the interkinetic nuclear migration of cortical progenitor cells
    Sayaka Minobe
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Aichi, Japan
    Neurosci Res 63:294-301. 2009
    ..Similar inhibitory effects were obtained by forced expression of a dominant-negative Rac1. These results suggest that Rac may play a role in interkinetic nuclear migration in the developing mouse brain...
  10. ncbi request reprint Differential expression of Pax6 and Ngn2 between pair-generated cortical neurons
    Ayano Kawaguchi
    Laboratory for Cell Culture Development, Brain Science Institute, RIKEN, Wako, Saitama, Japan
    J Neurosci Res 78:784-95. 2004
    ..We suggest that pair progenitor cells contribute to the generation of neuronal diversity through cell-intrinsic heterogeneity and asymmetric division...
  11. doi request reprint Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages
    Takayuki Uchida
    Department of Biomedical Science, Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho ku, Nagoya, Aichi 467 8603, Japan
    J Neurosci 29:10653-62. 2009
    ..It is thus strongly suggested that Reelin exerts critical actions on migrating projection neurons at their early/premigratory stages en route to their final destinations, in the developing cerebral cortex and cerebellum...
  12. ncbi request reprint Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis
    Daijiro Konno
    Laboratory for Cell Asymmetry, Center for Developmental Biology, RIKEN, and CREST, Japan Science and Technology Corporation, RIKEN, 2 2 3 Minatojima minamimachi, Chuou ku, Kobe 650 0047, Japan
    Nat Cell Biol 10:93-101. 2008
    ..Our results suggest that planar mitosis ensures the self-renewal of neuroepithelial progenitors by one daughter inheriting both apical and basal compartments during neurogenesis...
  13. ncbi request reprint Survey of the morphogenetic dynamics of the ventricular surface of the developing mouse neocortex
    Yuji Nishizawa
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Showa, Nagoya, Aichi, Japan
    Dev Dyn 236:3061-70. 2007
    ..Planar divisions oriented along the lateral-medial axis were less abundant than those oriented along the rostral-caudal axis at E10 and E11, but basal body distribution in each endfoot was random...
  14. doi request reprint Periventricular notch activation and asymmetric Ngn2 and Tbr2 expression in pair-generated neocortical daughter cells
    Wataru Ochiai
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi 466 8550, Japan
    Mol Cell Neurosci 40:225-33. 2009
    ..Many of the nascent cells exhibited pin-like morphology with a short ventricular process, suggesting periventricular presentation of Notch ligands to these cells...
  15. doi request reprint TAG-1-assisted progenitor elongation streamlines nuclear migration to optimize subapical crowding
    Mayumi Okamoto
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nat Neurosci 16:1556-66. 2013
    ..Thus, INM is essential for preventing overcrowding of nuclei and their somata, thereby ensuring normal brain histogenesis. ..
  16. ncbi request reprint Modern slice culture for direct observation of production and migration of brain neurons
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya 466 8550, Japan
    Nagoya J Med Sci 67:65-70. 2005
    ..Dynamic cellular behaviors can then be vividly captured without destroying tissue structures...
  17. ncbi request reprint Transformation of pin-like ventricular zone cells into cortical neurons
    Wataru Ochiai
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Neurosci Res 57:326-9. 2007
    ..Subsequently, they become multipolar upon entry into the subventricular zone...
  18. ncbi request reprint Visualization of cell cycling by an improvement in slice culture methods
    Takaki Miyata
    Laboratory for Cell Culture Development, Advanced Technology Development Center, Brain Science Institute, RIKEN, Wako, Saitama, Japan
    J Neurosci Res 69:861-8. 2002
    ....
  19. ncbi request reprint Midkine, a heparin-binding growth factor, is expressed in neural precursor cells and promotes their growth
    Peng Zou
    Department of Biochemistry, Center for Neurological Disease and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Neurochem 99:1470-9. 2006
    ..These results indicate that midkine is involved in the growth of neural precursor cells and suggest that the interaction with heparan sulfate proteoglycans is important in midkine action to these cells...
  20. ncbi request reprint Morphological asymmetry in dividing retinal progenitor cells
    Kanako Saito
    Laboratory for Cell Culture Development, Brain Science Institute, RIKEN, Wako, Saitama 351 0198, Japan
    Dev Growth Differ 45:219-29. 2003
    ....
  21. doi request reprint Visualizing spatiotemporal dynamics of multicellular cell-cycle progression
    Asako Sakaue-Sawano
    Laboratory for Cell Function and Dynamics, Advanced Technology Development Group, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako City, Saitama 351 0198, Japan
    Cell 132:487-98. 2008
    ..These mice and cell lines will serve as model systems permitting unprecedented spatial and temporal resolution to help us better understand how the cell cycle is coordinated with various biological events...
  22. doi request reprint Mechanisms that regulate the number of neurons during mouse neocortical development
    Takaki Miyata
    Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi 466 8550, Japan
    Curr Opin Neurobiol 20:22-8. 2010
    ..We discuss here recent advances in understanding these key aspects that are fundamental for normal brain development...
  23. doi request reprint Local application of neurotrophins specifies axons through inositol 1,4,5-trisphosphate, calcium, and Ca2+/calmodulin-dependent protein kinases
    Shinichi Nakamuta
    1Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya 466 8550, Japan
    Sci Signal 4:ra76. 2011
    ..These results identify a role for IP(3)-Ca(2+)-CaMKK signaling in axon specification...
  24. doi request reprint Photopic electroretinograms of mGluR6-deficient mice
    Toshiyuki Koyasu
    Department of Ophthalmology, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Curr Eye Res 33:91-9. 2008
    ..To study the properties of the photopic electroretinograms (ERGs) of the metabotropic glutamate receptor subtype 6 (mGluR6)-deficient mice and to investigate the contribution of cone ON-and OFF-pathways to the mouse photopic ERGs...
  25. doi request reprint Shootin1 acts in concert with KIF20B to promote polarization of migrating neurons
    Tamar Sapir
    Department of Molecular Genetics, Weizmann Institute of Science, 76100 Rehovot, Israel
    J Neurosci 33:11932-48. 2013
    ..Collectively, our data demonstrate the importance of the Shootin1/KIF20B interaction to the dynamic process of pyramidal neuronal polarization and migration...
  26. ncbi request reprint Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex
    Koji Shinozaki
    Department of Morphogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, 2 2 1 Honjo, Kumamoto 860 0811, Japan
    Development 129:3479-92. 2002
    ....
  27. doi request reprint Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells
    Ki Jun Yoon
    Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang, Kyungbuk, 790 784, South Korea
    Neuron 58:519-31. 2008
    ..Our results reveal that not only newborn neurons but also IPs are essential Notch-ligand-presenting cells for maintaining RGC stemness during both symmetric and asymmetric divisions...
  28. ncbi request reprint Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex
    Fumiyasu Imai
    Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, 3 9 Fuku ura, Kanazawa Ku, Yokohama 236 0004, Japan
    Development 133:1735-44. 2006
    ..Therefore, we concluded that, at least in the later stages of neurogenesis, regulation of cell cycle exit is independent of adherens junctions...
  29. ncbi request reprint Induction of oligodendrocyte progenitors in dorsal forebrain by intraventricular microinjection of FGF-2
    Masae Naruse
    Department of Physiological Sciences, School of Life Science, The Graduate University for Advanced Studies, Hayama, Miura, Kanagawa 240 0193, Japan
    Dev Biol 297:262-73. 2006
    ..These results demonstrate that the dorsal embryonic forebrain in vivo has the potential to generate OLPs in the presence of normal positional cues and that this can be driven by FGF-2 independent of Shh signaling...
  30. ncbi request reprint Pax6 transcription factor is required for the interkinetic nuclear movement of neuroepithelial cells
    Hiroshi Tamai
    Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research, Tohoku University School of Medicine, 2 1, Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Genes Cells 12:983-96. 2007
    ..Our results suggest the possibility that Pax6 regulates the INM by stabilizing the centrosome at the apical side...
  31. ncbi request reprint Both type-I hemidesmosomes and adherens-type junctions contribute to the cell-substratum adhesion system in myoepithelial cells
    Jun Uematsu
    Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya 464 8602, Japan
    Eur J Cell Biol 84:407-15. 2005
    ..These observations demonstrate that, in addition to their cytoskeleton, myoepithelial cells have both epithelial- and smooth muscle-type cell-substratum adhesion structures, i.e. HDs and dense plaque-like adherens junctions...
  32. doi request reprint Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors
    Takehiko Sunabori
    Department of Physiology, Keio University School of Medicine, Tokyo 160 8582, Japan
    J Cell Sci 121:1204-12. 2008
    ..Collectively, these findings demonstrate precisely orchestrated gene regulation that correlates with the 3D morphological changes in neural progenitor cells in vivo...
  33. ncbi request reprint Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia
    Yoshiki Yagita
    Division of Strokology, Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    J Neurosci Res 69:750-6. 2002
    ..In contrast, very few nestin-positive cells were labeled by BrdU. Our results suggest that neuronal progenitor cells in the SGZ expressed Msi1 but not nestin...
  34. ncbi request reprint The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex
    Syu ichi Hirai
    Department of Molecular Biology, Graduate School of Medical Science, Yokohama City University, Yokohama 236 0004, Japan
    J Neurosci 26:11992-2002. 2006
    ..These data suggest that DLK plays a significant role in the coordinated regulation of radial migration and axon projection by modulating JNK activity...
  35. ncbi request reprint Increased proliferation of neural progenitor cells but reduced survival of newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats
    Ken Ichiro Takasawa
    Division of Strokology, Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    J Cereb Blood Flow Metab 22:299-307. 2002
    ..These results showed that focal ischemia stimulated the proliferation of neuronal progenitor cells, but did not support survival of newborn cells in the contralateral hippocampus...