Sayo Kawai

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. pmc Factors associated with serum CA19-9 levels among healthy children: a cross-sectional study
    Sayo Kawai
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Japan
    BMC Clin Pathol 12:23. 2012
  2. ncbi request reprint Multiplex PCR with confronting two-pair primers for CYP1A1 Ile462Val, GSTM1, GSTT1, and NQO1 C609T
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Asian Pac J Cancer Prev 6:346-52. 2005
  3. doi request reprint Smoking and serum CA19-9 levels according to Lewis and secretor genotypes
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Cancer 123:2880-4. 2008
  4. ncbi request reprint No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW
    Yukako Hinohara
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:93-100. 2013
  5. ncbi request reprint Significant association between PTPN11 polymorphism and gastric atrophy among Japanese Brazilians
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Gastric Cancer 9:277-83. 2006
  6. ncbi request reprint DPP4 genetic variants influence baseline prostate-specific antigen levels: the J-MICC study
    Takahiro Higashibata
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:73-80. 2013
  7. doi request reprint Significant association of urokinase plasminogen activator Pro141Leu with serum lipid profiles in a Japanese population
    Takashi Tamura
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Gene 524:363-7. 2013
  8. ncbi request reprint Study profile on baseline survey of Daiko Study in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study)
    Emi Morita
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 73:187-95. 2011
  9. ncbi request reprint Association between decreased kidney function and endotoxin receptor CD14 C-159T polymorphism among Japanese health check-up examinees
    Rieko Okada
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Ren Fail 29:967-72. 2007
  10. ncbi request reprint Serum folate and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism adjusted for folate intake
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    J Epidemiol 18:125-31. 2008

Detail Information

Publications36

  1. pmc Factors associated with serum CA19-9 levels among healthy children: a cross-sectional study
    Sayo Kawai
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Japan
    BMC Clin Pathol 12:23. 2012
    ..This is the first study reporting the distribution of serum CA19-9 levels among cancer-free children as well as their parents, taking into account the Lewis and secretor gene polymorphism and physical growth...
  2. ncbi request reprint Multiplex PCR with confronting two-pair primers for CYP1A1 Ile462Val, GSTM1, GSTT1, and NQO1 C609T
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Asian Pac J Cancer Prev 6:346-52. 2005
    ..This convenient genotyping would be applied for cancer prevention especially in Asian Pacific regions, where expensive genotyping methods are hardly available...
  3. doi request reprint Smoking and serum CA19-9 levels according to Lewis and secretor genotypes
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Cancer 123:2880-4. 2008
    ..When hemoglobin A1c was further adjusted, the association became stronger (p = 0.0027). In addition to polymorphic variations, some components of cigarette smoke may influence the production or destruction of CA19-9...
  4. ncbi request reprint No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW
    Yukako Hinohara
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:93-100. 2013
    ..24) for CT genotype and OR=0.98 (0.84-1.32) for TT genotype, relative to CC genotype. The present study indicated no association between SUA and MTHFR C677T genotype, after the influences of ABCG2 Q126X and SLC22A12 W258X were removed...
  5. ncbi request reprint Significant association between PTPN11 polymorphism and gastric atrophy among Japanese Brazilians
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Gastric Cancer 9:277-83. 2006
    ..pylori-seropositive subjects. This study aimed to examine the reproducibility of the association among Japanese residing in a different circumstance...
  6. ncbi request reprint DPP4 genetic variants influence baseline prostate-specific antigen levels: the J-MICC study
    Takahiro Higashibata
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:73-80. 2013
    ..006), compared with the most common haplotype, T-A. In summary, our study suggests that DPP4 genetic variants influence baseline PSA levels, especially in men aged between 60 and 69...
  7. doi request reprint Significant association of urokinase plasminogen activator Pro141Leu with serum lipid profiles in a Japanese population
    Takashi Tamura
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Gene 524:363-7. 2013
    ..11 (95%CI; 1.00-1.23) and 1.16 (95%CI; 1.03-1.30) for those with Leu allele relative to ProPro. This study suggested that PLAU Pro141Leu (rs2227564) is significantly associated with serum lipid levels in a Japanese population...
  8. ncbi request reprint Study profile on baseline survey of Daiko Study in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study)
    Emi Morita
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 73:187-95. 2011
    ..Current drinkers included 74.9% (n=1099) of males and 45.9% (n=1699) of females. Lifestyle data and specimens were successfully collected to examine any associations among disease biomarkers, lifestyles, and genotypes...
  9. ncbi request reprint Association between decreased kidney function and endotoxin receptor CD14 C-159T polymorphism among Japanese health check-up examinees
    Rieko Okada
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Ren Fail 29:967-72. 2007
    ..This study was conducted to determine whether this polymorphism is associated with decreased kidney function...
  10. ncbi request reprint Serum folate and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism adjusted for folate intake
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    J Epidemiol 18:125-31. 2008
    ..Since studies considering folate intake are limited, we examined the association between folate intake and serum folate levels, according to the genotype...
  11. ncbi request reprint Associations between a PTPN11 polymorphism and gastric atrophy--opposite in Uzbekistan to that in Japan
    Nobuyuki Hamajima
    Department of Preventive Medicine Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550 Japan
    Asian Pac J Cancer Prev 9:217-20. 2008
    ..18 (95% confidence interval, 0.04-0.86) for intron 3 GG genotype relative to AA genotype. Since the finding was opposite to that among Japanese, the H. pylori strains and/or lifestyle in Uzbekistan might modify the association...
  12. doi request reprint Association between KLK3 rs2735839 G/A polymorphism and serum PSA levels in Japanese men
    Syunsuke Nobata
    Seirei Preventive Health Care Center, Hamamatsu, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Urol Int 89:39-44. 2012
    ..To clarify the association of kallikrein-related peptidase 3 (KLK3) rs2735839 G/A polymorphism with serum prostate-specific antigen (PSA) levels in Japanese men...
  13. doi request reprint Significant interaction between LRP2 rs2544390 in intron 1 and alcohol drinking for serum uric acid levels among a Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Gene 503:131-6. 2012
    ....
  14. pmc No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanese
    Simon Itou
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550 Japan
    Int J Med Sci 4:98-104. 2007
    ..pylori infection and subsequent gastric atrophy, indicating that even if H. pylori infection influences the risk of atherosclerosis, the influence may not be through the elevation of homocysteine...
  15. pmc Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Int J Med Sci 4:1-6. 2007
    ..pylori seropositive subjects...
  16. ncbi request reprint No association between Helicobacter pylori seropositivity and ornithine decarboxylase (ODC) A317G polymorphism, and no modification by NAD(P)H:qinone oxidoreductase 1 (NQO1) C609T
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 69:17-22. 2007
    ..pylori infection. The higher frequency of the ODC 317A allele in the Japanese population than that in the Caucasian population is firstly reported. The genetic traits through the ODC-polyamine pathway will be further investigated...
  17. doi request reprint Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Mol Genet Metab 103:378-82. 2011
    ..This study was the first report to estimate the impact of SLC2A9 rs11722228 on SUA levels. Since the allele frequency of rs11722228 is similar among different ethnic groups, the impact remains to be examined in other ethnic groups...
  18. ncbi request reprint Applicability of allele/genotype frequency from documented controls for case-control studies on genotypes among Japanese: MTHFR C677T as an example
    Kenta Iida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 10:231-6. 2009
    ....
  19. doi request reprint Significant association between methylenetetrahydrofolate reductase 677T allele and hyperuricemia among adult Japanese subjects
    Simon Itou
    Division of Thoracic Surgery, Aichi Cancer Center Hospital, Chikusa ku, Nagoya, Japan
    Nutr Res 29:710-5. 2009
    ..This new view may partly explain the inconsistent results on the association of the MTHFR polymorphism with SUA...
  20. ncbi request reprint Association of obesity and diabetes with serum prostate-specific antigen levels in Japanese males
    Mariko Naito
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 74:285-92. 2012
    ..Our findings suggest that the pre-overweight men had increased PSA levels, and the diabetes was associated with a reduction of PSA levels in elderly...
  21. ncbi request reprint Prevalence of Helicobacter pylori infection measured with urinary antibody in an urban area of Japan, 2008-2010
    Takashi Tamura
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 74:63-70. 2012
    ..pylori infection observed in Nagoya seemed to be lower than the corresponding prevalence reported in other studies of Japan. That lower rate might be due to the reduced exposure from improved urban sanitary conditions...
  22. ncbi request reprint Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study
    Kenji Wakai
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    J Epidemiol 21:223-35. 2011
    ..To detect gene-environment interactions in the development of lifestyle-related diseases, and especially cancer, the Japan Multi-institutional Collaborative Cohort (J-MICC) Study was launched in 2005...
  23. ncbi request reprint Modification of the effect of smoking on cholesterol in Japanese carriers of a PTPN11 polymorphism
    Rieko Okada
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Mol Med Report 1:595-8. 2008
    ..039; HDL-C, p=0.020). These data suggest that cigarette smoking might alter the metabolism of cholesterol in Japanese PTPN11 AA genotype carriers...
  24. ncbi request reprint Alternative genotyping method of GSTT1 null/present polymorphism
    Mariko Naito
    Department of Preventive Medicine Biostatistics and Medical Decision Making, 65 Tsurumai cho Showa ku, Nagoya 466 8550, Japan
    Expert Rev Mol Diagn 6:873-7. 2006
    ....
  25. pmc Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study
    Rieko Okada
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Nephrol 13:2. 2012
    ....
  26. pmc No association between the frequency of forest walking and blood pressure levels or the prevalence of hypertension in a cross-sectional study of a Japanese population
    Emi Morita
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Tsurumai cho, Showa Ku, Nagoya, Japan
    Environ Health Prev Med 16:299-306. 2011
    ..To study the non-temporary effects of successive walks in forested areas (shinrin-yoku) on hypertension prevalence and blood pressure levels...
  27. doi request reprint Renal hyperfiltration in prediabetes confirmed by fasting plasma glucose and hemoglobin A1c
    Rieko Okada
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ren Fail 34:1084-90. 2012
    ..The aim of the study was to confirm that glomerular hyperfiltration, an early and reversible stage of kidney damage, is associated in patients with prediabetes and prehypertension...
  28. ncbi request reprint Association of UGT1A1 Gly71Arg with urine urobilinogen
    Ryuji Kataoka
    Medical Student of Nagoya University School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 73:33-40. 2011
    ..Although the significant association for urobilinogen was contrary to the biological expectation, this study indicated that UGTIA1 Gly71Arg may be a genetic factor of urine urobilinogen...
  29. ncbi request reprint The ACE gene polymorphism is associated with the incidence of gastric cancer among H. pylori seropositive subjects with atrophic gastritis
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Asian Pac J Cancer Prev 6:464-7. 2005
    ..Confirmation of the association between ACE polymorphisms and development of gastric cancer requires much larger studies, and the biological role also needs to be fully elucidated...
  30. doi request reprint Association of calcium urolithiasis with urokinase P141L and 3'-UTR C>T polymorphisms in a Japanese population
    Shoichi Hagikura
    Department of Urology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Aichi, 466 8550, Japan
    Urolithiasis 41:47-52. 2013
    ..028). P141L and 3'-UTR polymorphisms of the urokinase gene are not associated with urolithiasis in a Japanese population...
  31. pmc eNOS genotype modifies the effect of leisure-time physical activity on serum triglyceride levels in a Japanese population
    Takahiro Higashibata
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Lipids Health Dis 11:150. 2012
    ..The purpose of this study was to examine possible associations of the NOS3 T-786C polymorphism (rs2070744) with serum lipid levels on the basis of lifestyle factors for tailoring prevention of dyslipidemia...
  32. doi request reprint Matrix metalloproteinase-9 gene polymorphisms and chronic kidney disease
    Rieko Okada
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Japan
    Am J Nephrol 36:444-50. 2012
    ..MMPs degrade extracellular matrix proteins in the glomerulus, and play important roles in kidney disease progression...
  33. doi request reprint Gene variants in PPARD and PPARGC1A are associated with timing of natural menopause in the general Japanese population
    Hirokazu Uemura
    Department of Preventive Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Maturitas 71:369-75. 2012
    ....
  34. ncbi request reprint Preventive medical services not covered by public health insurance at Daiko Medical Center in Japan, 2004-2011
    Takashi Tamura
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 74:115-21. 2012
    ..Our unique trial showed that continuing to provide uninsured preventive services at a clinic was difficult in Japan without the affiliation of hospitals/clinics providing medical services covered by public health insurance...
  35. ncbi request reprint Improvements in Helicobacter pylori eradication rates through clinical CYP2C19 genotyping
    Takashi Tamura
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 73:25-31. 2011
    ..28, p=0.051) for the latter period relative to the former period among those less than 70 years of age. Those results suggested that the routine genetic test which allows a choice of the RAM regimen for R M improved the eradication rate...
  36. ncbi request reprint Helicobacter pylori eradication as a preventive tool against gastric cancer
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 5:246-52. 2004
    ..Studies on such interactions should provide useful information for anti-H. pylori preventive strategies...