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Genomes and Genes | Hiroshi InagakiSummaryAffiliation: Nagoya City University Country: Japan Publications
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Publications
Detection of API2-MALT1 fusion transcripts in cytologic specimens of patients with pulmonary mucosa-associated lymphoid tissue lymphomaHiroshi Inagaki
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya
Int J Hematol 82:59-62. 2005..The detection of API2-MALT1 fusion as carried out with these specimens would be useful as an ancillary assay for the diagnosis, staging, and follow-up of pulmonary MALT lymphoma...- Clonality assay of hematopoietic disorders: significance of the buccal epithelium as non-hematopoietic control and of 95% rejection limit as a novel criterion for monoclonalityH Inagaki
Department of Pathology, Nagoya City University Medical School, Kawasumi, Mizuho ku, Nagoya 467 8601, Japan
Jpn J Cancer Res 92:1305-12. 2001.... - Mucosa-associated lymphoid tissue lymphoma: molecular pathogenesis and clinicopathological significanceHiroshi Inagaki
Department of Pathology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan
Pathol Int 57:474-84. 2007..The focus of the present review is on the recent progress made in elucidating MALT lymphomagenesis and its clinicopathological impact, especially in terms of the effect of API2-MALT1 fusion on this unique tumor... 
Primary thymic extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue type exhibits distinctive clinicopathological and molecular featuresHiroshi Inagaki
Department s of Pathology, Nagoya City University Medical School, Nagoya, Japan
Am J Pathol 160:1435-43. 2002....- Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcomaH Inagaki
Department of Pathology, Nagoya City University Medical School, Nagoya, Japan
Mod Pathol 13:482-8. 2000..These data suggested that SYT-SSX fusion type is associated with tumor cell proliferative activity and prognosis of patients who have SS... - Gastric MALT lymphomas are divided into three groups based on responsiveness to Helicobacter Pylori eradication and detection of API2-MALT1 fusionHiroshi Inagaki
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Am J Surg Pathol 28:1560-7. 2004..This 3-group categorization may be helpful for a comprehensive understanding of gastric MALT lymphoma... - Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous systemH Inagaki
Department of Pathology, Nagoya City University Medical School, Mizuho ku, Nagoya 467 8601, Japan
Histochem Cell Biol 113:37-41. 2000..Northern blot analysis showed that DRPs were differentially expressed in the mouse and human intestines, supporting the results of ISH. These data suggest that DRPs play a role not only in the CNS but also in the ENS... - Primary cutaneous marginal zone B-cell lymphoma: a molecular and clinicopathologic study of 24 asian casesChunmei Li
Department of Pathology, Nagoya City Unviersity Medical School, Nagoya, Japan
Am J Surg Pathol 27:1061-9. 2003.... - Prognostic significance of CD44v6 in diffuse large B-cell lymphomaH Inagaki
Department of Pathology, Nagoya City University Medical School, Nagoya, Japan
Mod Pathol 12:546-52. 1999.... 
Prognostic significance of p27Kip1, Ki-67, and CRTC1-MAML2 fusion transcript in mucoepidermoid carcinoma: a molecular and clinicopathologic study of 101 casesSatoru Miyabe
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Kawasumi, Nagoya, Japan
J Oral Maxillofac Surg 67:1432-41. 2009..In the present study, we investigated the prognostic significance of p27Kip1, Ki-67, and CRTC1 (also called MECT1, TORC1, and WAMTP1)-MAML2 fusion in MEC...- A complement-dependent cytotoxicity-enhancing anti-CD20 antibody mediating potent antitumor activity in the humanized NOD/Shi-scid, IL-2Rγ(null) mouse lymphoma modelFumihiko Sato
Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho chou, Mizuho ku, Nagoya, Aichi, 467 8601, Japan
Cancer Immunol Immunother 59:1791-800. 2010..In the near future, the efficacy of this type of CDC-enhancing antibody will be determined in clinical trials in humans... - Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinomaTakahisa Nakayama
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
Mod Pathol 22:1575-81. 2009..Mucoepidermoid carcinomas possessing CRTC3-MAML2 fusion may be associated with favorable clinicopathological features and patients may be younger than those with CRTC1-MAML2 fusion or those with no detectable gene fusion... - Immunoglobulin VH gene analysis in gastric MALT lymphomasHidenori Sakuma
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Mod Pathol 20:460-6. 2007..pylori-associated, B cell subset and may not often progress to those that are inflammation-independent (Groups B and C). Although considered to be common in this tumor, ongoing mutation may be infrequent when assessed by strict criteria... - Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid, IL-2R gamma(null) mice in vivoAsahi Ito
Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467 8601, Japan
J Immunol 183:4782-91. 2009..Furthermore, the potent ADCC mediated by defucosylated anti-CCR4 mAb, observed here in vivo in humanized mice, will be exploited in clinical trials in the near future... - p16/INK4a gene methylation is a frequent finding in pulmonary MALT lymphomas at diagnosisHisashi Takino
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Mod Pathol 18:1187-92. 2005..These findings suggest that p16 methylation is not associated with tumor progression, but may be an early event in MALT lymphomagenesis that might be maintained through the progression of the tumor... - Prognostic significance of NPM-ALK fusion transcript overexpression in ALK-positive anaplastic large-cell lymphomaChunmei Li
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Mod Pathol 20:648-55. 2007..Overexpression of the NPM-ALK fusion transcript may be associated with a poor prognosis of the patients with ALK(+) anaplastic large-cell lymphomas... - API2-MALT1 fusion gene in colorectal lymphomaSumie Takase Sakugawa
Department of Pathology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
Mod Pathol 16:1232-41. 2003..Thus, API2-MALT1-positive tumors should be cared for as a more aggressive subgroup and be followed for a longer time... - Defucosylated anti CC chemokine receptor 4 monoclonal antibody combined with immunomodulatory cytokines: a novel immunotherapy for aggressive/refractory Mycosis fungoides and Sezary syndromeHiroki Yano
Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
Clin Cancer Res 13:6494-500. 2007.... - Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilegeTakashi Ishida
Department of Internal Medicine and Molecular Science and Clinical Pathology, Nagoya City University Graduate School of Medical Sciences, Kawasumi, Mizuho chou, Mizuho ku, Nagoya shi, Aichi, Japan
Cancer Res 66:5716-22. 2006.... - CXC chemokine receptor 3 and CC chemokine receptor 4 expression in T-cell and NK-cell lymphomas with special reference to clinicopathological significance for peripheral T-cell lymphoma, unspecifiedTakashi Ishida
Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Clin Cancer Res 10:5494-500. 2004..We suggest that a specific therapy targeting the CCR4 molecule may be developed as an alternative treatment for patients with CCR4-positive tumors... - Tax is a potential molecular target for immunotherapy of adult T-cell leukemia/lymphomaSusumu Suzuki
Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, Japan
Cancer Sci 103:1764-73. 2012..The present study not only provides a strong rationale for exploiting Tax as a possible target for ATL immunotherapy but also contributes to our understanding of the immunopathogenesis of ATL... - Characterization of chromosomal aberrations in thymic MALT lymphomaSatoru Kominato
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
Pathol Int 62:93-8. 2012..In conclusion, the present study showed that thymic MALT lymphoma has a characteristic pattern of chromosomal aberrations that may be similar to those of other autoimmune-associated MALT lymphomas... - MECT1-MAML2 fusion transcript defines a favorable subset of mucoepidermoid carcinomaMitsukuni Okabe
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
Clin Cancer Res 12:3902-7. 2006..This fusion transcript has been frequently detected in mucoepidermoid carcinoma and shown to be involved in the transformation of epithelial cells. However, its clinicopathologic significance remains unclear... - Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rgamma(null) mouse modelAsahi Ito
Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho chou, Mizuho ku, Nagoya, Aichi, Japan
Cancer Immunol Immunother 58:1195-206. 2009..The second aim was to evaluate ADCC mediated in these humanized mice by the defucosylated anti-CC chemokine receptor 4 (CCR4) monoclonal antibody (mAb) which we have developed and which is now in phase I clinical trials... - Follicular lymphoma frequently originates in the salivary glandSatoko Nakamura
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Pathol Int 56:576-83. 2006..The observed differences in age of onset, background of autoimmune disease, and lesion site suggests that the pathogenesis of FL may differ from that of MALT lymphoma... - Angioimmunoblastic T-cell lymphoma mice modelFumihiko Sato
Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho chou, Mizuho ku, Nagoya, Aichi 467 8601, Japan Department of Anatomic Pathology and Molecular Diagnostics, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho chou, Mizuho ku, Nagoya, Aichi 467 8601, Japan
Leuk Res 37:21-7. 2013..This is the first report of reconstituting follicular helper T (TFH) function in AITL cells in an experimental model, and this is consistent with the theory that TFH cell is the cell of origin of AITL tumor cells... - Forkhead box P1 overexpression and its clinicopathologic significance in peripheral T-cell lymphoma, not otherwise specifiedSeiji Yamada
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467 8601, Japan
Hum Pathol 43:1322-7. 2012..The clinicopathologic significance of forkhead box P1 overexpression in peripheral T-cell lymphoma, not otherwise specified, may be different from that in B-cell lymphomas... - Primary mucosa-associated lymphoid tissue lymphoma of the prostate: tumor relapse 7 years after local therapyChunmei Li
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
Pathol Int 58:191-5. 2008..The present case suggests that despite tumor recurrence, prostatic MALT lymphoma is indolent, and function-preserving therapy is warranted... - Analysis of API2-MALT1 fusion, trisomies, and immunoglobulin VH genes in pulmonary mucosa-associated lymphoid tissue lymphomaHongjing Xia
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467 8601, Japan
Hum Pathol 42:1297-304. 2011..This observation suggests that these gene abnormalities may occur in microenvironments found before or outside of follicular germinal centers... - Primary cutaneous marginal zone B-cell lymphoma: a molecular and clinicopathological study of cases from Asia, Germany, and the United StatesHisashi Takino
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Mod Pathol 21:1517-26. 2008..Borrelia infection and API2-MALT1 fusion are not significant in this tumor. Methylation of DAPK and p16(INK4a) genes is a frequent event in this lymphoma at its initial presentation, but may not be associated with tumor progression... - CC chemokine receptor 4-positive diffuse large B-cell lymphoma involving the skin: a case reportTakashi Ishida
Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Sciences, Japan
Int J Hematol 82:148-51. 2005..To the best of our knowledge, this report is the first of a CCR4-positive B-cell lymphoma. The present case provides new insights into the pathogenesis of skin involvement in B-cell lymphomas... - API2-MALT1 fusion defines a distinctive clinicopathologic subtype in pulmonary extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissueMitsukuni Okabe
Department of Pathology, Nagoya City University Medical School, Nagoya, Japan
Am J Pathol 162:1113-22. 2003..quot; Aberrant nuclear BCL10 expression may have a possible role as a tool to screen for this API2-MALT1 fusion. A large-scale study with a long follow-up is necessary to establish the prognostic significance of API2-MALT1 fusion... - Immunoglobulin VH genes in thymic MALT lymphoma are biased toward a restricted repertoire and are frequently unmutatedMegumi Yoshida
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
J Pathol 208:415-22. 2006..The observed patterns of V(H) usage and mutations suggested that specific antigens may play a pathologically relevant role in the genesis or progression of thymic MALT lymphoma... - Impact of CRTC1/3-MAML2 fusions on histological classification and prognosis of mucoepidermoid carcinomaYoshihide Okumura
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Histopathology 59:90-7. 2011..The aim of study was to evaluate the impact of CRTC1-MAML2 and CRTC3-MAML2 fusions on the histological classification of mucoepidermoid carcinoma (MEC) of the salivary glands and on the prognosis of patients... - Gastric low-grade B-cell MALT lymphoma: treatment, response, and genetic alterationTsuneya Nakamura
Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan
J Gastroenterol 38:921-9. 2003..Investigation in the future will clarify this issue and establish the clinical implication of such genetic alteration as the predictive factor for gastric MALT lymphoma... - Overexpression of carboxylesterase-2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan (CPT-11), for multiple myelomaHiroki Yano
Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
Cancer Sci 99:2309-14. 2008..When a combination of CPT-11 and bortezomib was administered, the subcutaneous tumors completely disappeared. Thus, clinical trials on CPT-11 in patients with relapsed or refractory MM are warranted... - Small-cell lung cancer arising after chemotherapy for a patient with lymphoma of pulmonary mucosa-associated lymphoid tissue-a case reportMakoto Nakao
Department of Medical Oncology and Immunology, Nagoya City University School of Medical Sciences, Mizuho ku, Nagoya, Japan
Gan To Kagaku Ryoho 36:1711-4. 2009..To our knowledge, this is a rare case of small cell lung cancer arising from the treatment of lymphoma of pulmonary MALT... - The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-Cell leukemia/lymphomaTakashi Ishida
Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan
Clin Cancer Res 10:7529-39. 2004.... - Spontaneous regression of intraoral mucosa-associated lymphoid tissue lymphoma: molecular study of a caseHidenori Sakuma
Department of Pathology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Pathol Int 56:331-5. 2006..When minimal residual disease is detected, close follow up is necessary for early detection of the tumor relapse... - Clinicopathological significance of MAML2 gene split in mucoepidermoid carcinomaHaruna Noda
Department of Anatomic Pathology and Molecular Diagnostics, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan Department of Maxillofacial Surgery, Aichi Gakuin University School of Dentistry, Nagoya, Japan
Cancer Sci 104:85-92. 2013..The presence of the MAML2 gene split defines a distinct mucoepidermoid carcinoma subset that is associated clinicopathologically with favorable tumor features. (Cancer Sci 2013; 104: 85-92)... - Defucosylated anti-CCR4 monoclonal antibody (KW-0761) for relapsed adult T-cell leukemia-lymphoma: a multicenter phase II studyTakashi Ishida
Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho chou, Mizuho ku, Nagoya, Aichi, 467 8601, Japan
J Clin Oncol 30:837-42. 2012.... - Frequent occurrence of CCND1 deregulation in patients with early stages of plasma cell dyscrasiaKazuhisa Miura
Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Science, Mizuho ku, Nagoya 467 8601, Japan
Cancer Sci 94:350-4. 2003..This suggests to us that cyclin D1 deregulation due to the presence of t(11;14) is involved in the early development of plasma cell neoplasms, and that this event alone is not enough for the development of symptomatic myeloma... - Involvement of the chromosomal translocation t(11;18) in some mucosa-associated lymphoid tissue lymphomas and diffuse large B-cell lymphomas of the ocular adnexa: evidence from multiplex reverse transcriptase-polymerase chain reaction and fluorescence in Shinichi Takada
Department of Pathology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
Mod Pathol 16:445-52. 2003..These findings indicate a possibility that at least in the ocular adnexa, some diffuse large B-cell lymphomas are derived from mucosa-associated lymphoid tissue lymphomas... - Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka Lymphoma Study GroupNaoki Wada
Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
Histopathology 60:924-32. 2012..Diffuse large B cell lymphoma (DLBCL) occasionally shows an interfollicular pattern of proliferation (DLBCL-IF) preserving lymphoid follicles. In this study, clinicopathological findings in 31 cases of DLBCL-IF were analysed... - Analysis of VH gene rearrangement and somatic hypermutation in type 1 autoimmune pancreatitisFumihiro Okumura
Departments of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Pathol Int 62:318-23. 2012..1%) (P= 0.010). Our study suggests that an increased rate of unmutated or less mutated VH genes may be characteristic of type 1 AIP and might play a role in the development of this disease... - p185(HER-2/neu) and p21(CIP1/WAF1) expression in primary tumors and lymph node metastases in non-small cell lung cancerKenji Akita
Second Department of Internal Medicine, Nagoya City University Medical School, Mizuho ku, Nagoya 467 8601, Japan
Jpn J Cancer Res 93:1007-11. 2002..However we failed to detect any correlation between p185(HER-2/neu) and p21(CIP1/WAF1) expression. Our results suggested that expression of both p185(HER-2/neu) and p21(CIP1/WAF1) is concordant between primary and metastatic tumors... - Influence of histochemical and immunohistochemical stains on polymerase chain reactionT Murase
Department of Pathology, Nagoya City University Medical School, Nagoya, Japan
Mod Pathol 13:147-51. 2000..The immunohistochemical visualization with DAB or new fuchsin yields no unfavorable effects. A successful PCR amplification may not be expected in sections that are pretreated in a microwave oven or pressure cooker... - The CCR4 as a novel-specific molecular target for immunotherapy in Hodgkin lymphomaT Ishida
Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Sciences, Mizuho chou, Mizuho ku, Nagoya shi, Aichi, Japan
Leukemia 20:2162-8. 2006..Collectively, this study strongly indicates that anti-CCR4 mAb could be a novel treatment modality for patients with CCR4-positive HL... - Thymic sarcomatoid carcinoma with skeletal muscle differentiation: report of two cases, one with cytogenetic analysisT Eimoto
Department of Pathology, Nagoya City University School of Medicine, Kawasumi, Mizuho ku, Nagoya 467 8601, Japan
Histopathology 40:46-57. 2002..We report two such cases in which the tumour cells showed a prominent rhabdomyoblastic differentiation and analyse whether these tumours retain an epithelial nature at least in part... - API2-MALT1 fusion transcripts involved in mucosa-associated lymphoid tissue lymphoma: multiplex RT-PCR detection using formalin-fixed paraffin-embedded specimensH Inagaki
Department of Pathology, Nagoya City University Medical School, Nagoya, Japan
Am J Pathol 158:699-706. 2001..Our multiplex RT-PCR assay, which can be used for routinely-processed paraffin samples, should serve as a useful molecular tool for clarifying the clinicopathological significance of API2-MALT1 fusion in MALT lymphoma... - Successful treatment of nasal T-cell lymphoma with a combination of local irradiation and high-dose chemotherapyTakaomi Sanda
Second Department of Internal Medicine, Nagoya City University Medical School, Nagoya, Japan
Int J Hematol 75:195-200. 2002..This therapy resulted in CR. Our results suggest that this lymphoma subtype may be cured by means of intensive treatment soon after diagnosis... - Clonality analysis of different histological components in combined small cell and non-small cell carcinoma of the lungTakayuki Murase
Department of Pathology, Nagoya City University Medical School, Japan
Hum Pathol 34:1178-84. 2003..This tumorigenesis process may explain the relative rarity of combined small cell and non-small cell carcinoma, which occurs primarily in the peripheral lung, an infrequent site of squamous cell carcinoma... - Prognostic significance of p27 and Ki-67 expression in mucoepidermoid carcinoma of the intraoral minor salivary glandM Okabe
Department of Pathology, Nagoya City University Medical School, Nagoya, Japan
Mod Pathol 14:1008-14. 2001..These data suggest that p27 may be useful in estimating prognosis of the patients who have mucoepidermoid carcinoma of the intraoral minor salivary gland... - Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody, in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphomaKazuhito Yamamoto
Department of Hematology and Cell Therapy, Aichi Cancer Center, Nagoya, Aichi, Japan
J Clin Oncol 28:1591-8. 2010..This phase I study assessed the safety, pharmacokinetics, recommended phase II dose and efficacy of KW-0761 in patients with relapsed CCR4-positive adult T-cell leukemia-lymphoma (ATL) or peripheral T-cell lymphoma (PTCL)... - Primary ureteral mucosa-associated lymphoid tissue (MALT) lymphoma--pathological and radiological findingsMasaki Hara
Department of Radiology, Nagoya City University Medical School, Kawasumi, Japan
Radiat Med 20:41-4. 2002..We suggest that it is useful for the differential diagnosis of ureter masses that some MALT lymphomas may show a low signal intensity on T2-weighted MR images... - rDLG6: a novel homolog of Drosophila DLG expressed in rat brainH Inagaki
Department of Chemistry, National Industrial Research Institute of Nagoya, 1 1 Hirate cho, Kita ku, Nagoya, 462 8510, Japan
Biochem Biophys Res Commun 265:462-8. 1999..GST pull-down assays showed that the PDZ domain of rDLG6 protein binds to the C-terminus of the AMPA (alpha-Amino-3-hydroxy-5-Methyl-isoxazole-4-Propionic Acid) receptor GluR2 subunit... 
Reactive lymphoid hyperplasia of the liver in a patient with colon cancer: report of two casesHiroki Takahashi
Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho cho, Mizuho ku, Nagoya, Japan
BMC Gastroenterol 6:25. 2006..Reactive lymphoid hyperplasia (RLH) of the liver is very rarely reported, and we encountered two cases of RLH of the liver in a patient with colon cancer...- Nasal NK-cell lymphoma followed by relapse in the uterine cervixTakayuki Murase
Department of Pathology, Nagoya City University Medical School, Nagoya, Japan
Leuk Lymphoma 43:203-6. 2002..This case may be of value in elucidating the biological behavior and natural history of NK-cell lymphoma... - Analysis of VH gene rearrangement and somatic hypermutation in Sjogren's syndrome and IgG4-related sclerosing sialadenitisH Sakuma
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
Scand J Immunol 72:44-9. 2010..0001, respectively). This finding suggests that some autoantibodies encoded by germline or less mutated VH genes may fail to be eliminated and could play a role in the development of SS and IgG4-related sclerosing sialadenitis... - Osteoprotegerin levels before and after renal transplantationT Sato
Department of Transplant Surgery, Nagoya 2nd Red Cross Hospital, Nagoya, Japan
Am J Kidney Dis 38:S175-7. 2001..Serum OPG declines for the first 2 weeks after RTX owing to functioning allograft and decreases again for the next 2 weeks because of steroids and possible immunosuppressive agents... - Aldolase C is localized in neuroendocrine cellsH Inagaki
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
Experientia 44:749-51. 1988..Aldolase C was found to be localized in various types of neuroendocrine cells; in the pituitary gland, thyroid, pancreas, adrenal gland, bronchus, and gastrointestinal tract... - Multiple myeloma oncogene 1 (MUM1)/interferon regulatory factor 4 (IRF4) upregulates monokine induced by interferon-gamma (MIG) gene expression in B-cell malignancyM Uranishi
Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Leukemia 19:1471-8. 2005..Leukemia (2005) 19, 1471-1478. doi:10.1038/sj.leu.2403833; published online 16 June 2005... - Characteristics of gastric B-cell lymphoma of mucosa-associated lymphoid tissue type involving multiple organsMasahiro Iwano
Department of Gastroenterology and Endoscopic Medicine, Kyoto University Hospital, 54 Shogoin, Sakyo, 606-8507, Kyoto, Japan
J Gastroenterol 39:739-46. 2004..Patients with gastric MALT lymphoma with multiple organ involvement who are positive for H. pylori are resistant to eradication therapy... - Clinical significance of CCR4 expression in adult T-cell leukemia/lymphoma: its close association with skin involvement and unfavorable outcomeTakashi Ishida
Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Science, Nagoya 467-8601, Japan
Clin Cancer Res 9:3625-34. 2003..Multivariate analysis confirmed that CCR4 expression was an independent and significant prognostic factor (P < 0.05). Thus, our finding may provide a novel insight into not only the biological but also the clinical features of ATLL... - Human immunodeficiency virus (HIV)-negative, API2-MALT1 fusion-negative bronchus-associated lymphoid tissue (BALT) lymphoma in a young maleMasashi Okamoto
Second Department of Medicine, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Japan
Leuk Lymphoma 45:2165-8. 2004..It appears necessary to clarify whether atopy might play a role in the pathogenesis of API2-MALT1(-) BALT lymphoma for HIV(-) young patients who do not exhibit any other antecedent chronic antigenic stimulations... - Rapid development of diffuse large B-Cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphomaMasahiro Iwano
Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Am J Gastroenterol 101:2878-83. 2006..pylori eradication for low-grade MALT lymphoma... - Diffuse large B-cell lymphoma with extra Bcl-2 gene signals detected by FISH analysis is associated with a "non-germinal center phenotype"Shigeru Kusumoto
Hematology Division, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
Am J Surg Pathol 29:1067-73. 2005..The DLBCLs with Bcl-2 protein overexpression were classified into at least two heterogeneous molecular groups, based on the results of the FISH analysis... - Clinical implications of nodal marginal zone B-cell lymphoma among Japanese: study of 65 casesMasaru Kojima
Department of Pathology and Clinical Laboratories, Gunma Cancer Center Hospital, Ohta, Japan
Cancer Sci 98:44-9. 2007..DLBCL + MALT type exhibited significantly poorer 5-year overall survival than the splenic variant. The recognition of DLBCL + MALT type appears important. No API2-MALT1 fusion transcript was detected in any of the 14 cases examined...