Nobuyuki Hamajima

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. ncbi request reprint Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma
    Keitaro Matsuo
    Aichi Cancer Center, Division of Epidemiology and Prevention, Nagoya, Japan
    Am J Hematol 77:351-7. 2004
  2. pmc Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor pylori seropositivity, gastric atrophy and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Gastroenterol 9:51. 2009
  3. pmc eNOS genotype modifies the effect of leisure-time physical activity on serum triglyceride levels in a Japanese population
    Takahiro Higashibata
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Lipids Health Dis 11:150. 2012
  4. pmc Factors associated with serum CA19-9 levels among healthy children: a cross-sectional study
    Sayo Kawai
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Japan
    BMC Clin Pathol 12:23. 2012
  5. ncbi request reprint Significant interaction between LRP2 rs2544390 in intron 1 and alcohol drinking for serum uric acid levels among a Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Gene 503:131-6. 2012
  6. pmc Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study
    Rieko Okada
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Nephrol 13:2. 2012
  7. pmc Smoking cessation, alcohol intake and transient increase in the risk of metabolic syndrome among Japanese smokers at one health checkup institution
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Public Health 9:263. 2009
  8. pmc HIV prevalence and factors associated with HIV infection among male injection drug users under 30: a cross-sectional study in Long An, Vietnam
    Thu Minh T Tran
    Planning Department, National Institute of Hygiene and Epidemiology, 1 Yersin Hai Ba Trung, Hanoi, Vietnam
    BMC Public Health 6:248. 2006
  9. pmc Effectiveness of communication campaign on iron deficiency anemia in Kyzyl-Orda region, Kazakhstan: a pilot study
    Ainur Baizhumanova
    Department of Young Leaders Program for Medical Administration and Politics, Graduate School of Medicine, Nagoya University, 65 Tsurumai Cho, Nagoya, 466 8550, Japan
    BMC Blood Disord 10:2. 2010
  10. ncbi request reprint A pilot study on genotype announcement to induce smoking cessation by Japanese smokers
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550 Japan
    Asian Pac J Cancer Prev 5:409-13. 2004

Detail Information

Publications131 found, 100 shown here

  1. ncbi request reprint Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma
    Keitaro Matsuo
    Aichi Cancer Center, Division of Epidemiology and Prevention, Nagoya, Japan
    Am J Hematol 77:351-7. 2004
    ..Lack of association with MTR polymorphism was also confirmed...
  2. pmc Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor pylori seropositivity, gastric atrophy and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Gastroenterol 9:51. 2009
    ....
  3. pmc eNOS genotype modifies the effect of leisure-time physical activity on serum triglyceride levels in a Japanese population
    Takahiro Higashibata
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Lipids Health Dis 11:150. 2012
    ..The purpose of this study was to examine possible associations of the NOS3 T-786C polymorphism (rs2070744) with serum lipid levels on the basis of lifestyle factors for tailoring prevention of dyslipidemia...
  4. pmc Factors associated with serum CA19-9 levels among healthy children: a cross-sectional study
    Sayo Kawai
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Japan
    BMC Clin Pathol 12:23. 2012
    ..This is the first study reporting the distribution of serum CA19-9 levels among cancer-free children as well as their parents, taking into account the Lewis and secretor gene polymorphism and physical growth...
  5. ncbi request reprint Significant interaction between LRP2 rs2544390 in intron 1 and alcohol drinking for serum uric acid levels among a Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Gene 503:131-6. 2012
    ....
  6. pmc Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study
    Rieko Okada
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Nephrol 13:2. 2012
    ....
  7. pmc Smoking cessation, alcohol intake and transient increase in the risk of metabolic syndrome among Japanese smokers at one health checkup institution
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Public Health 9:263. 2009
    ..To verify the hypothesis that smoking cessation may increase the risk of MetS, a follow-up study taking drinking habit into account was conducted for the examinees at one health checkup institution...
  8. pmc HIV prevalence and factors associated with HIV infection among male injection drug users under 30: a cross-sectional study in Long An, Vietnam
    Thu Minh T Tran
    Planning Department, National Institute of Hygiene and Epidemiology, 1 Yersin Hai Ba Trung, Hanoi, Vietnam
    BMC Public Health 6:248. 2006
    ..This study was conducted to facilitate the development of such activities by describing transmission risks of young IDUs and evaluating factors in association with HIV infection...
  9. pmc Effectiveness of communication campaign on iron deficiency anemia in Kyzyl-Orda region, Kazakhstan: a pilot study
    Ainur Baizhumanova
    Department of Young Leaders Program for Medical Administration and Politics, Graduate School of Medicine, Nagoya University, 65 Tsurumai Cho, Nagoya, 466 8550, Japan
    BMC Blood Disord 10:2. 2010
    ..The present study aimed to evaluate the prevalence of anemia, iron deficiency and IDA before and after the campaign. In addition, knowledge about IDA and its prevention, as well as awareness about fortified wheat flour, was assessed...
  10. ncbi request reprint A pilot study on genotype announcement to induce smoking cessation by Japanese smokers
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550 Japan
    Asian Pac J Cancer Prev 5:409-13. 2004
    ..Genotype announcements related to susceptibility to hazardous effects of smoking may be effective to induce smoking cessation...
  11. ncbi request reprint Genotype announcement to Japanese smokers who attended a health checkup examination
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    J Epidemiol 16:45-7. 2006
    ..Genotype announcement may be one of the effective methods to induce smoking cessation, but the studies are limited throughout the world...
  12. ncbi request reprint Genetic factors involved in the development of Helicobacter pylori-related gastric cancer
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cancer Sci 97:1129-38. 2006
    ..pylori-related. In order to elucidate the genetic traits of H. pylori-related gastric cancer, stepwise evaluation will be required...
  13. ncbi request reprint Precise definition of anonymization in genetic polymorphism studies
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550 Japan
    Asian Pac J Cancer Prev 5:83-8. 2004
    ..The proposed definitions will be useful when we describe and discuss the preferable mode of anonymization for a given polymorphism study...
  14. ncbi request reprint Helicobacter pylori eradication as a preventive tool against gastric cancer
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 5:246-52. 2004
    ..Studies on such interactions should provide useful information for anti-H. pylori preventive strategies...
  15. pmc Serum uric acid distribution according to SLC22A12 W258X genotype in a cross-sectional study of a general Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Med Genet 12:33. 2011
    ..This study examined serum uric acid (SUA) distribution according to SLC22A12 W258X genotype in a general Japanese population...
  16. ncbi request reprint The Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) to detect gene-environment interactions for cancer
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 8:317-23. 2007
    ..The data of second survey and follow-up will be linked using J-MICC ID. This study is expected to produce many findings on lifestyle and genetic traits associated with lifestyle-related diseases including cancer among Japanese...
  17. ncbi request reprint Associations between a PTPN11 polymorphism and gastric atrophy--opposite in Uzbekistan to that in Japan
    Nobuyuki Hamajima
    Department of Preventive Medicine Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550 Japan
    Asian Pac J Cancer Prev 9:217-20. 2008
    ..18 (95% confidence interval, 0.04-0.86) for intron 3 GG genotype relative to AA genotype. Since the finding was opposite to that among Japanese, the H. pylori strains and/or lifestyle in Uzbekistan might modify the association...
  18. ncbi request reprint Minimal sizes of cases with a susceptible genotype and minimal odds ratios among susceptible individuals in case-control studies
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Asian Pac J Cancer Prev 6:165-9. 2005
    ....
  19. doi request reprint Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Mol Genet Metab 103:378-82. 2011
    ..This study was the first report to estimate the impact of SLC2A9 rs11722228 on SUA levels. Since the allele frequency of rs11722228 is similar among different ethnic groups, the impact remains to be examined in other ethnic groups...
  20. ncbi request reprint Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects
    Yoshimitsu Niwa
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cancer Lett 219:183-90. 2005
    ..82, 95% CI=1.36-5.82), especially of type-I tumors (OR=3.24, 95% CI=1.53-6.87). In contrast, there was no significant difference in the p53 Arg72Pro genotype frequency between the controls and cases...
  21. ncbi request reprint No association between AICDA 7888 C/T polymorphism, Helicobacter pylori seropositivity, and the risk of atrophic gastritis and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Gastric Cancer 13:43-9. 2010
    ..We investigated the association of the AICDA 7888 C/T polymorphism with H. pylori infection and the risk of gastric cancer and atrophic gastritis in Japanese subjects...
  22. ncbi request reprint No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW
    Yukako Hinohara
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:93-100. 2013
    ..24) for CT genotype and OR=0.98 (0.84-1.32) for TT genotype, relative to CC genotype. The present study indicated no association between SUA and MTHFR C677T genotype, after the influences of ABCG2 Q126X and SLC22A12 W258X were removed...
  23. ncbi request reprint Significant association between PTPN11 polymorphism and gastric atrophy among Japanese Brazilians
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Gastric Cancer 9:277-83. 2006
    ..pylori-seropositive subjects. This study aimed to examine the reproducibility of the association among Japanese residing in a different circumstance...
  24. ncbi request reprint Polymorphisms of p53 Arg72Pro, p73 G4C14-to-A4T14 at exon 2 and p21 Ser31Arg and the risk of non-Hodgkin's lymphoma in Japanese
    Asahi Hishida
    Department of Molecular Medicine and Clinical Science, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Leuk Lymphoma 45:957-64. 2004
    ..08; 95% CI, 1.11-3.90, P = 0.023). Further examination with a sufficiently larger population and other ethnicities are required to confirm our findings...
  25. ncbi request reprint Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in Japanese subjects
    Yoshimitsu Niwa
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Gynecol Oncol 99:43-9. 2005
    ..In this study, genetic polymorphisms, XRCC1 Arg399Gln and OGG1 Ser326Cys were examined with reference to cervical cancer risk in a population-based incident case-control study in Japan...
  26. ncbi request reprint Helicobacter pylori infection and cytokine gene polymorphisms in Uzbeks
    Shavkat Abdiev
    Department of Surgery I, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 72:167-72. 2010
    ..pylori among Uzbeks. In addition to confirming the above associations, lifestyle interactions with the genotypes also remain to be elucidated...
  27. pmc Significant association between Helicobacter pylori infection and serum C-reactive protein
    Yoshiko Ishida
    Department of Preventive Medicine, Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Med Sci 5:224-9. 2008
    ..Helicobacter pylori (H. pylori) infection in gastric mucosa may cause systemic inflammatory reaction. This study aimed to examine the association between the infection and serum high sensitivity C-reactive protein (hsCRP)...
  28. ncbi request reprint Genotype announcement in a genetic polymorphism study for health checkup examinees at Nagoya University Hospital
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 67:45-9. 2004
    ..To date, there have been no complaints from the participants, indicating that the announcement of polymorphism genotypes may be accepted differently from that of hereditary disease genotypes...
  29. ncbi request reprint GSTT1 and GSTM1 deletions, NQO1 C609T polymorphism and risk of chronic myelogenous leukemia in Japanese
    Asahi Hishida
    Department of Hematology, Nagoya University Graduate School of Medicine, Tsurumai cho 65, Showa Ku, Nagoya 466 8550, Japan
    Asian Pac J Cancer Prev 6:251-5. 2005
    ..Incidence case-control studies with a larger statistical power are now required to confirm our findings...
  30. doi request reprint Significant association of RUNX3 T/A polymorphism at intron 3 (rs760805) with the risk of gastric atrophy in Helicobacter pylori seropositive Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    J Gastroenterol 44:1165-71. 2009
    ..pylori seropositivity and gastric atrophy in Japanese people...
  31. ncbi request reprint Applicability of allele/genotype frequency from documented controls for case-control studies on genotypes among Japanese: MTHFR C677T as an example
    Kenta Iida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 10:231-6. 2009
    ....
  32. pmc HLA-A alleles and the risk of cervical squamous cell carcinoma in Japanese women
    Satoyo Hosono
    Deparment of Gynecology and Obstetrics, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Epidemiol 20:295-301. 2010
    ..We conducted a case-control study to examine the relationship between human leukocyte antigen-A (HLA-A) allele polymorphism and the pathogenesis of cervical neoplasia among Japanese women...
  33. pmc Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Int J Med Sci 4:1-6. 2007
    ..pylori seropositive subjects...
  34. doi request reprint Toll-like receptor 4 +3725 G/C polymorphism, Helicobacter pylori seropositivity, and the risk of gastric atrophy and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Helicobacter 14:47-53. 2009
    ..We investigated the associations of TLR4+3725 G/C polymorphism, another functional polymorphism of TLR4, with risk of gastric cancer and gastric atrophy in Japanese...
  35. ncbi request reprint Polymorphism of dihydropyrimidine dehydrogenase (DPYD) Cys29Arg and risk of six malignancies in Japanese
    Daisuke Tanaka
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 67:117-24. 2005
    ..52 (0.71-3.28) and 0.31 (0.71-1.34), respectively. Although prevalent cases were used, this study suggested that the influence of DPYD T85C posed only a limited risk for the six malignancies...
  36. ncbi request reprint MTHFR, MTR and MTRR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study
    Asahi Hishida
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Int Urol Nephrol 45:1613-20. 2013
    ..To clarify the associations of MTHFR, MTR, and MTRR polymorphisms with the risk of CKD in Japanese, we examined this association among Japanese subjects using cross-sectional data...
  37. ncbi request reprint DPP4 genetic variants influence baseline prostate-specific antigen levels: the J-MICC study
    Takahiro Higashibata
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:73-80. 2013
    ..006), compared with the most common haplotype, T-A. In summary, our study suggests that DPP4 genetic variants influence baseline PSA levels, especially in men aged between 60 and 69...
  38. ncbi request reprint Association between serum pepsinogens and polymorphismof PTPN11 encoding SHP-2 among Helicobacter pylori seropositive Japanese
    Yasuyuki Goto
    Department of Gastroenterology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Cancer 118:203-8. 2006
    ..The functional consequences of the G/A polymorphism remain to be elucidated...
  39. ncbi request reprint Significant association of interleukin 8 -251T/A polymorphism with smoking behavior in a Japanese population
    Hidemi Ito
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya, 464 8681, Japan
    J Hum Genet 50:567-73. 2005
    ..33-0.82, P=0.004) for ever having smoked and 0.55 (0.33-0.92, P=0.023) for being a current smoker. Our results suggest that the inflammatory-prone genotype of IL8 may act to deter initiation or characteristics of the smoking habit...
  40. ncbi request reprint Association between Helicobacter pylori seropositivity and NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism observed in outpatients and health checkup examinees
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya 466 8550, Japan
    Gastric Cancer 8:12-7. 2005
    ..This study investigated the associations of functional polymorphisms of the NQO1, GSTM1, and GSTT1 genes of detoxification enzymes, with the seropositivity, as well as with pepsinogen levels, as markers of gastric atrophy...
  41. ncbi request reprint Smoking and serum CA19-9 levels according to Lewis and secretor genotypes
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Cancer 123:2880-4. 2008
    ..When hemoglobin A1c was further adjusted, the association became stronger (p = 0.0027). In addition to polymorphic variations, some components of cigarette smoke may influence the production or destruction of CA19-9...
  42. ncbi request reprint Associations between disease risk and eight polymorphisms adopted for genotype announcements at Nagoya University Hospital
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 67:51-8. 2004
    ..Since showed a potential for widespread use in health checkups, the information on the above polymorphisms seems worth documenting. Although there have been no complaints from the participants to date, careful treatments are requested...
  43. ncbi request reprint P53, p21, and p73 gene polymorphisms in gastric carcinoma
    Osamu Shirai
    Department of Gastroenterology, Nagoya University Graduate School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya, Japan
    Hepatogastroenterology 57:1595-601. 2010
    ..The aim of this study was to evaluate the association of genetic polymorphisms of p53, p21, and p73 genes with susceptibility to gastric carcinoma (GC), its clinicopathologic features, and prognosis...
  44. ncbi request reprint Serum folate and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism adjusted for folate intake
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    J Epidemiol 18:125-31. 2008
    ..Since studies considering folate intake are limited, we examined the association between folate intake and serum folate levels, according to the genotype...
  45. ncbi request reprint No association of an SDHC gene polymorphism with gastric cancer
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Descision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550 Japan
    Asian Pac J Cancer Prev 7:525-8. 2006
    ..Although the polymorphism at the 3'-untranslated region could be hypothesized to be functional, this study did not demonstrate any significant association of the SDHC gene polymorphism with gastric atrophy and cancer...
  46. ncbi request reprint Polymorphism in the hMSH2 gene (gIVS 12-6T-->C) and risk of non-Hodgkin lymphoma in a Japanese population
    Asahi Hishida
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, 464 8681, Nagoya, Japan
    Cancer Genet Cytogenet 147:71-4. 2003
    ..44-2.54), or CT and CC genotypes combined together (OR=1.44, 95% CI, 0.94-2.23) demonstrated significant OR. Further investigations with sufficiently larger populations and in other ethnicities are required to verify this association...
  47. ncbi request reprint Association of transporter associated with antigen processing (TAP) gene polymorphisms in donors with acute cellular rejection in living donor liver transplantation
    Hideya Kamei
    Department of Transplantation Surgery, Nagoya University, Nagoya, Japan
    J Gastrointestin Liver Dis 22:167-71. 2013
    ..The aim of this study was to determine whether TAP1 and TAP2 gene polymorphisms in the donor have affected on ACR incidence in living donor liver transplantation (LDLT)...
  48. doi request reprint The effect of β-carotene on lumbar osteophyte formation
    Shiro Imagama
    Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Spine (Phila Pa 1976) 36:2293-8. 2011
    ..Cross-sectional cohort study of elderly people...
  49. ncbi request reprint Study profile on baseline survey of Daiko Study in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study)
    Emi Morita
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 73:187-95. 2011
    ..Current drinkers included 74.9% (n=1099) of males and 45.9% (n=1699) of females. Lifestyle data and specimens were successfully collected to examine any associations among disease biomarkers, lifestyles, and genotypes...
  50. ncbi request reprint Associations of TNF-A-1031TT and -857TT genotypes with Helicobacter pylori seropositivity and gastric atrophy among Japanese Brazilians
    Yoshiko Atsuta
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Int J Clin Oncol 11:140-5. 2006
    ..This study examined the associations of this seropositivity and serum pepsinogen (PG) levels with these genotypes in Japanese Brazilians...
  51. ncbi request reprint Use of duplex PCR-CTPP methods for CYP2E1RsaI/IL-2 T-330G and IL-1B C-31T/TNF-A T-1031C polymorphisms
    Yoshiko Atsuta
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya City, Japan
    Mol Diagn 9:89-94. 2005
    ..Many studies have reported associations between the above polymorphisms and risk of diseases including cancers and inflammatory diseases...
  52. ncbi request reprint Association of the NAD(P)H: quinone oxidoreductase C609T polymorphism and the risk of cervical cancer in Japanese subjects
    Yoshimitsu Niwa
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Gynecol Oncol 96:423-9. 2005
    ..In this study, genetic polymorphisms, NQO1 C609T, GSTM1 positive/null, and GSTT1 positive/null, were examined with reference to cervical cancer risk in a population-based incident case-control study in Japanese...
  53. doi request reprint PRKCH gene polymorphism is associated with the risk of severe gastric atrophy
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, 466 8550, Japan
    Gastric Cancer 13:90-4. 2010
    ..To elucidate its applicability in the development of GA and GC, this study aimed to investigate the associations of the PRKCH polymorphism with the risks of GA and GC...
  54. ncbi request reprint Multiplex PCR with confronting two-pair primers for CYP1A1 Ile462Val, GSTM1, GSTT1, and NQO1 C609T
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Asian Pac J Cancer Prev 6:346-52. 2005
    ..This convenient genotyping would be applied for cancer prevention especially in Asian Pacific regions, where expensive genotyping methods are hardly available...
  55. doi request reprint Significant association of urokinase plasminogen activator Pro141Leu with serum lipid profiles in a Japanese population
    Takashi Tamura
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Gene 524:363-7. 2013
    ..11 (95%CI; 1.00-1.23) and 1.16 (95%CI; 1.03-1.30) for those with Leu allele relative to ProPro. This study suggested that PLAU Pro141Leu (rs2227564) is significantly associated with serum lipid levels in a Japanese population...
  56. doi request reprint Significant association between methylenetetrahydrofolate reductase 677T allele and hyperuricemia among adult Japanese subjects
    Simon Itou
    Division of Thoracic Surgery, Aichi Cancer Center Hospital, Chikusa ku, Nagoya, Japan
    Nutr Res 29:710-5. 2009
    ..This new view may partly explain the inconsistent results on the association of the MTHFR polymorphism with SUA...
  57. pmc Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study
    Kenji Wakai
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    J Epidemiol 21:223-35. 2011
    ..To detect gene-environment interactions in the development of lifestyle-related diseases, and especially cancer, the Japan Multi-institutional Collaborative Cohort (J-MICC) Study was launched in 2005...
  58. ncbi request reprint Helicobacter pylori seropositivity and the myeloperoxidase G-463A polymorphism in combination with interleukin-1B C-31T in Japanese health checkup examinees
    Nobuyuki Katsuda
    Nagoya Kita Health Center, Nagoya, Japan
    Jpn J Clin Oncol 33:192-7. 2003
    ....
  59. doi request reprint Association of serum carotenoids, retinol, and tocopherols with radiographic knee osteoarthritis: possible risk factors in rural Japanese inhabitants
    Taisuke Seki
    Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    J Orthop Sci 15:477-84. 2010
    ..To determine the association between serum antioxidants and radiographic knee osteoarthritis, we undertook a cross-sectional investigation in a community-based study in Japan...
  60. ncbi request reprint Relationship between body mass index and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort (JACC) study
    Yoshimitsu Niwa
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Obstet Gynaecol Res 31:452-8. 2005
    ..Here we investigated this relation using data from the Japan Collaborative Cohort Study for the Evaluation of Cancer Risk, which was initiated in 1988...
  61. doi request reprint KLOTHO gene polymorphisms G-395A and C1818T are associated with low-density lipoprotein cholesterol and uric acid in Japanese hemodialysis patients
    Yasuhiko Shimoyama
    Department of Advanced Medicine for Uremia, Nagoya University School of Medicine, Nagoya, Japan
    Am J Nephrol 30:383-8. 2009
    ..This study aimed to investigate the association of the KLOTHO gene single nucleotide polymorphisms (SNPs), G-395A and C1818T, with various laboratory data in 219 Japanese hemodialysis (HD) patients...
  62. ncbi request reprint No association between Helicobacter pylori seropositivity and ornithine decarboxylase (ODC) A317G polymorphism, and no modification by NAD(P)H:qinone oxidoreductase 1 (NQO1) C609T
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 69:17-22. 2007
    ..pylori infection. The higher frequency of the ODC 317A allele in the Japanese population than that in the Caucasian population is firstly reported. The genetic traits through the ODC-polyamine pathway will be further investigated...
  63. ncbi request reprint The ACE gene polymorphism is associated with the incidence of gastric cancer among H. pylori seropositive subjects with atrophic gastritis
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Asian Pac J Cancer Prev 6:464-7. 2005
    ..Confirmation of the association between ACE polymorphisms and development of gastric cancer requires much larger studies, and the biological role also needs to be fully elucidated...
  64. doi request reprint Association between KLK3 rs2735839 G/A polymorphism and serum PSA levels in Japanese men
    Syunsuke Nobata
    Seirei Preventive Health Care Center, Hamamatsu, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Urol Int 89:39-44. 2012
    ..To clarify the association of kallikrein-related peptidase 3 (KLK3) rs2735839 G/A polymorphism with serum prostate-specific antigen (PSA) levels in Japanese men...
  65. doi request reprint No associations of Toll-like receptor 2 (TLR2) -196 to -174del polymorphism with the risk of Helicobacter pylori seropositivity, gastric atrophy, and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Showa Ku, Japan
    Gastric Cancer 13:251-7. 2010
    ..This study aimed to confirm the associations of the polymorphism with the risk of gastric cancer, as well as Helicobacter pylori seropositivity and the risk of gastric atrophy in Japanese...
  66. pmc No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanese
    Simon Itou
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550 Japan
    Int J Med Sci 4:98-104. 2007
    ..pylori infection and subsequent gastric atrophy, indicating that even if H. pylori infection influences the risk of atherosclerosis, the influence may not be through the elevation of homocysteine...
  67. ncbi request reprint Associations between serum C-reactive protein (CRP) levels and polymorphisms of CRP, interleukin 1B, and tumor necrosis factor genes among Japanese health checkup examinees
    Masato Kikuchi
    Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 8:87-92. 2007
    ..Since the biological mechanism is not clear, further investigations are required to confirm the association...
  68. ncbi request reprint Consumption of soy foods and the risk of breast cancer: findings from the Japan Collaborative Cohort (JACC) Study
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cancer Causes Control 18:801-8. 2007
    ..To examine whether soy foods really have protective effects against breast cancer and how their influence on breast cancer is modified according to menopausal status, we conducted a population-based, prospective cohort study in Japan...
  69. ncbi request reprint SLC22A12 W258X frequency according to serum uric acid level among Japanese health checkup examinees
    Sayaka Kuriki
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 73:41-8. 2011
    ..The observed SUA level changes in individuals with 258WX suggested that lifestyle factors could influence the levels of those with 258WX...
  70. ncbi request reprint Comparison of urinary concentrations of 3-phenoxybenzoic acid among general residents in rural and suburban areas and employees of pest control firms
    Akiko Kimata
    Program in Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Higashi ku, Nagoya, Japan
    Int Arch Occup Environ Health 82:1173-8. 2009
    ....
  71. ncbi request reprint Association between decreased kidney function and endotoxin receptor CD14 C-159T polymorphism among Japanese health check-up examinees
    Rieko Okada
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Ren Fail 29:967-72. 2007
    ..This study was conducted to determine whether this polymorphism is associated with decreased kidney function...
  72. ncbi request reprint Dietary factors protective against breast cancer in Japanese premenopausal and postmenopausal women
    Kaoru Hirose
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Int J Cancer 107:276-82. 2003
    ..61, 95% CI 0.41-0.91). Thus, traditional Japanese dietary factors may protect against breast cancer development, especially among postmenopausal women...
  73. ncbi request reprint Duplex polymerase chain reaction with confronting two-pair primers (PCR-CTPP) for genotyping alcohol dehydrogenase beta subunit (ADH2) and aldehyde dehydrogenase 2 (ALDH2)
    Akiko Tamakoshi
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Alcohol Alcohol 38:407-10. 2003
    ....
  74. ncbi request reprint Lymphotoxin-alpha polymorphism and the risk of cervical cancer in Japanese subjects
    Yoshimitsu Niwa
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cancer Lett 218:63-8. 2005
    ..64, 95% CI = 0.40-1.02; and OR = 0.45, 95% CI = 0.21-0.95, respectively), especially of SCC (OR = 0.54, 95% CI = 0.32-0.91; and OR = 0.39, 95% CI = 0.16-0.92, respectively)...
  75. ncbi request reprint Genetic polymorphisms of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro and the risk of cervical cancer in Japanese
    Yoshimitsu Niwa
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cancer Lett 205:55-60. 2004
    ..57; 95%CI, 0.99-2.48, P = 0.053). There was no significant difference in the p53 Arg72Pro genotype frequency between the controls and cases...
  76. ncbi request reprint Controls for monitoring the deterioration of stored blood samples in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study)
    Mariko Naito
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Nagoya J Med Sci 70:107-15. 2008
    ..The resulting findings will produce valuable information on the stability of the molecules, not only for the J-MICC Study, but also for other cohort studies...
  77. ncbi request reprint Helicobacter pylori seropositivity and IL-1B C-31T polymorphism among Japanese Brazilians
    Miyuki Uno
    Department of Clinical Laboratory, Aichi Cancer Center, Kanokoden, Chikusa ku, Nagoya, Japan
    Int J Mol Med 10:321-6. 2002
    ..8%, and had no association with the HP seropositivity. The observed association between HP+ and IL-1B -31TT indicated that the genetic trait also influences the susceptibility to HP for Japanese in Brazil...
  78. ncbi request reprint The association between tumour necrosis factor-alpha gene polymorphism and the susceptibility to rugal hyperplastic gastritis and gastric carcinoma
    Itaru Ohyama
    Department of Therapeutic Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Eur J Gastroenterol Hepatol 16:693-700. 2004
    ..The aim of this study was to clarify the association of tumour necrosis factor-alpha (TNFA) gene polymorphism with susceptibility to hyper-rugosity. We also examined the association of TNFA polymorphism with gastric carcinoma...
  79. ncbi request reprint A pilot study on inducement of smoking cessation by a simple 5A (asking, advice, assess, assist, and arrange) approach at outpatient clinics
    Kosuke Takahashi
    Department of Medicine, Division of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Asian Pac J Cancer Prev 7:131-5. 2006
    ..The findings may indicate that this simple practice at clinics is useful for smoking cessation strategy, although randomized trials are now required...
  80. ncbi request reprint L-myc genotype is associated with different susceptibility to lung cancer in smokers
    Hiroshi Kumimoto
    Central Laboratory and Radiation Biology, Aichi Cancer Center Hospital, Chikusa ku, Nagoya, Aichi 464 8681, Japan
    Jpn J Cancer Res 93:1-5. 2002
    ..The OR for smoking in SS-genotype patients diagnosed within 2 years was higher than that in other SS patients, suggesting that smoking-related lung cancer in SS genotype might exhibit a poorer prognosis...
  81. doi request reprint Polymorphism in resistin promoter region at -420 determines the serum resistin levels and may be a risk marker of stroke in Japanese type 2 diabetic patients
    Takayoshi Tsukahara
    Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya 466 8550, Japan
    Diabetes Res Clin Pract 84:179-86. 2009
    ..CG; OR 2.99, P=0.024, vs. GG; OR 4.49, P=0.010). These data suggested that the genotyping of resistin polymorphism at -420(C>G) can be a risk marker for stroke susceptibility in Japanese type 2 diabetic patients...
  82. ncbi request reprint Subjects with TNF-A-857TT and -1031TT genotypes showed the highest Helicobacter pylori seropositive rate compared with those with other genotypes
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, 466 8550, Nagoya, Japan
    Gastric Cancer 6:230-6. 2003
    ..The present study examined the associations of H. pylori with functional polymorphisms, TNF-A G-308A, C-857T, and T-1031C and TNF-B A252G in Japanese subjects...
  83. ncbi request reprint Persistent Helicobacter pylori infection and genetic polymorphisms of the host
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 66:103-17. 2003
    ..An effect on OR due to the involvement of unexposed subjects is demonstrated to elucidate a disadvantage in the studies done in areas where the majority of the population is not exposed to HP...
  84. ncbi request reprint [Genetic polymorphisms and cancer risk]
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Gan To Kagaku Ryoho 31:853-7. 2004
    ..However, the finding that the strength of association between lifestyle and disease occurrence is influenced by genotypes (gene-environment interaction), opens the door to genotype applications for disease prevention practice...
  85. ncbi request reprint A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung
    Hidemi Ito
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 12:258-65. 2002
    ..This study supported the first study by Sugimura et al (Cancer Epidemiol Biomarkers Prev, 1999; 8: 669-674), that the association of OGG1 Ser326Cys polymorphism was limited for the risk of lung adenocarcinoma...
  86. ncbi request reprint High anti-Helicobacter pylori antibody seropositivity associated with the combination of IL-8-251TT and IL-10-819TT genotypes
    Nobuyuki Hamajima
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Center, Nagoya, Japan
    Helicobacter 8:105-10. 2003
    ..This study examined associations between anti-Helicobacter pylori immunoglobulin G antibody seropositivity and functional polymorphisms of interleukin-8 T-251 A and interleukin-10 T-819C...
  87. ncbi request reprint Height, weight, menstrual and reproductive factors and risk of gastric cancer among Japanese postmenopausal women: analysis by subsite and histologic subtype
    Manami Inoue
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Int J Cancer 97:833-8. 2002
    ..From these results, however, it appears that height, weight, menstrual and reproductive factors have less impact on gastric cancer than environmental factors such as smoking and dietary habits or family history of gastric cancer...
  88. doi request reprint KLOTHO gene polymorphisms G-395A and C1818T are associated with lipid and glucose metabolism, bone mineral density and systolic blood pressure in Japanese healthy subjects
    Yasuhiko Shimoyama
    Clinical Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Nagoya 466 8550, Japan
    Clin Chim Acta 406:134-8. 2009
    ..We investigated the association of KLOTHO gene single nucleotide polymorphisms (SNPs) with various laboratory data in 476 Japanese healthy subjects...
  89. ncbi request reprint Dietary factors and the risk of gastric cancer among Japanese women: a comparison between the differentiated and non-differentiated subtypes
    Lucy Sayuri Ito
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Ann Epidemiol 13:24-31. 2003
    ....
  90. ncbi request reprint Aldehyde dehydrogenase 2 (ALDH2) genotype affects rectal cancer susceptibility due to alcohol consumption
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 12:70-6. 2002
    ..The alcohol related enzyme encoding gene ALDH2 has polymorphism Glu487Lys, and 487Lys allele is closely linked with phenotypic loss of enzyme activity...
  91. ncbi request reprint The plausibility of Helicobacter pylori-related infertility in Japan
    Shozo Kurotsuchi
    Department of Obstetrics and Gynecology and Department of Maternal and Perinatal Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Fertil Steril 90:866-8. 2008
    ..3%) vs. 37 of 183 patients (20.2%), respectively], which suggests a new concept: H. pylori-related infertility...
  92. ncbi request reprint Transforming growth factor B1 T29C polymorphism and breast cancer risk in Japanese women
    Asahi Hishida
    First Department of Internal Medicine, Nagoya University Graduate School of Medicine, Japan
    Breast Cancer 10:63-9. 2003
    ..This is a prevalent case-control study to examine the reported risk reduction for Japanese women...
  93. ncbi request reprint Cardiovascular disease mortality and serum carotenoid levels: a Japanese population-based follow-up study
    Yoshinori Ito
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    J Epidemiol 16:154-60. 2006
    ..Some observational epidemiologic studies suggest that dietary and serum carotenoids are associated with reduced cardiovascular disease mortality...
  94. doi request reprint Multivariate analysis of the pathologic features of esophageal squamous cell cancer: tumor budding is a significant independent prognostic factor
    Masahiko Koike
    Department of Surgery II, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Ann Surg Oncol 15:1977-82. 2008
    ..Tumor budding has been suggested to be a prognostic factor in various cancers but has never been studied in esophageal cancer...
  95. doi request reprint Combined effect of miR-146a rs2910164 G/C polymorphism and Toll-like receptor 4 +3725 G/C polymorphism on the risk of severe gastric atrophy in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Dig Dis Sci 56:1131-7. 2011
    ..A G/C polymorphism in miRNA-146a (rs2910164) was shown to be associated with the risk of hepatocellular carcinoma...
  96. ncbi request reprint No association between angiotensin I converting enzyme (ACE) I/D polymorphism and gastric cancer risk among Japanese
    Satoshi Hibi
    Department of Gastroenterology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 73:169-75. 2011
    ..61-1.89) for severe GA, respectively. In conclusion, there was no significant association of the ACE I/D polymorphism with the risk of gastric cancer. Among the controls, the polymorphism was not associated with the severity of GA...
  97. ncbi request reprint Comparison of sendai virus-mediated gene transfer efficiency to adhesive and floating adipose tissue-derived stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:601-9. 2009
    ..These data suggest that SeV transfection to ASCs in the floating state could therefore be useful for gene transfer technology...
  98. ncbi request reprint Quantum dots for labeling adipose tissue-derived stem cells
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:591-9. 2009
    ..These data suggest that QDs could be utilized for the labeling of ASCs...
  99. ncbi request reprint Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma
    Asahi Hishida
    Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya, Japan
    Haematologica 88:159-66. 2003
    ..We examined the associations between susceptibility to malignant lymphoma and these polymorphisms...
  100. ncbi request reprint Cell transplantation of adipose tissue-derived stem cells in combination with heparin attenuated acute liver failure in mice
    Hiroshi Yukawa
    Department of Advanced Medicine in Biotechnology and Robotics, Nagoya University Graduate School of Medicine, Nagoya 461 0047, Japan
    Cell Transplant 18:611-8. 2009
    ..In addition, all mice survived for at least the duration of the study period. In conclusion, the transplantation of ASCs in combination with heparin was thus found to effectively treat acute liver failure...
  101. pmc Association between vitamin D receptor gene haplotypes and chronic periodontitis among Japanese men
    Mariko Naito
    Department of Preventive Medicine Biostatistics, Medical Decision Making, Nagoya University Graduate School of Medicine, Tsurumai cho, Showa Ku, Nagoya, Japan
    Int J Med Sci 4:216-22. 2007
    ..We assessed the relationship between ApaI, BsmI, and FokI VDR polymorphisms and the risk of severe chronic periodontitis among Japanese adult men...