Research Topics
Genomes and GenesSpecies | Yasuaki DohiSummaryAffiliation: Nagoya City University Country: Japan Publications
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Detail Information
Publications
Coronary stenting in an elderly patient with an acute myocardial infarction at left main trunkKeita Sakurai
Division of Cardiology, Toyokawa City Hospital, Toyokawa, Japan
Am J Med Sci 327:94-7. 2004..We successfully dilated this calcified narrowing using a coronary stent, and the patient was discharged without complications 1 month later. The patient was asymptomatic 6 months later...- Candesartan, an angiotensin II type-1 receptor blocker, reduces cardiovascular events in patients on chronic haemodialysis--a randomized studyAkihiko Takahashi
Department of Internal Medicine, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
Nephrol Dial Transplant 21:2507-12. 2006..The present study was designed to investigate whether candesartan, an angiotensin II type-1 receptor blocker, reduces the incidence of cardiovascular events in these patients... - Effects of ascorbic acid on ambulatory blood pressure in elderly patients with refractory hypertensionKoichi Sato
Division of Clinical Research of Hypertension, Department of Internal Medicine, Nagoya City Johoku Hospital, Nagoya, Japan
Arzneimittelforschung 56:535-40. 2006..In contrast, ascorbic acid did not affect blood pressure in the adult group. These results suggest that ascorbic acid is useful for controlling blood pressure in elderly patients with refractory hypertension... - Effects of combination therapy with direct hemoperfusion using polymyxin B-immobilized fiber and oral vancomycin on fulminant pseudomembranous colitis with septic shockYoshihide Kimura
Department of Internal Medicine, Nagoya City Johoku Hospital, 2 15 Kaneda cho, Kita ku, Nagoya 462 0033, Japan
Dig Dis Sci 52:675-8. 2007..These cases strongly indicated that our combination therapy provides an important treatment for fulminant pseudomembranous colitis with septic shock... - Association among C-reactive protein, oxidative stress, and traditional risk factors in healthy Japanese subjectsYasuaki Dohi
Internal Medicine and Molecular Science, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
Int J Cardiol 115:63-6. 2007..This study was designed to examine the interrelationships among C-reactive protein (CRP), oxidative stress, and traditional cardiovascular risk factors... - Circulating thrombomodulin levels are related to latent progression of atherosclerosis in hypertensive patientsYasuaki Dohi
Internal Medicine and Molecular Science, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan
Hypertens Res 26:479-83. 2003.... - Candesartan reduces oxidative stress and inflammation in patients with essential hypertensionYasuaki Dohi
Division of Hypertension and Vascular Research, Internal Medicine and Molecular Science, Graduate School of Medical Sciences, Nagoya City University, Mizuho ku, Nagoya 467 8601, Japan
Hypertens Res 26:691-7. 2003..This may provide useful information for determining therapeutic strategies to minimize tissue injury by inflammation and oxidative stress in hypertensive patients... - Usefulness of dual 67Ga and 99mTc-sestamibi single-photon-emission CT scanning in the diagnosis of cardiac sarcoidosisAi Nakazawa
Internal Medicine and Molecular Science, Graduate School of Medical Sciences, Nagoya City University, Kawasumi 1, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
Chest 126:1372-6. 2004..These results suggest that dual SPECT scanning using Ga and Tc represents a very useful diagnostic imaging technique since it improves the diagnostic capability of Ga-SPECT to allow the highly specific diagnosis of cardiac sarcoidosis... 
Does B-type natriuretic peptide predict the new onset of hypertension?Hiroyuki Takase
Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan
Hypertens Res 31:1737-44. 2008..Measurements of BNP may serve as a complementary method for the prediction or confirmation of hypertension...- Renoprotective effect of calcium channel blockers in combination with an angiotensin receptor blocker in elderly patients with hypertension. A randomized crossover trial between benidipine and amlodipineKoichi Miyagawa
Department of Internal Medicine, Nagoya Kosein Geriatric Hospital, Nagoya, Japan
Clin Exp Hypertens 32:1-7. 2010..The results suggest the importance of selecting medications used in combination with ARB in hypertensive patients with chronic kidney disease... 
Increased reactive oxygen metabolites is associated with cardiovascular risk factors and vascular endothelial damage in middle-aged Japanese subjectsTomonori Sugiura
Department of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Vasc Health Risk Manag 7:475-82. 2011..The present study sought to investigate the usefulness of derivative reactive oxygen metabolites (d-ROM) as an oxidative stress marker for detecting endothelial damage in the clinical setting in subjects with early-stage atherosclerosis...- Carvedilol reduces elevated B-type natriuretic peptide in dialyzed patients without heart failure: cardioprotective effect of the beta-blockerMasayoshi Kojima
Department of Internal Medicine, Komono Kosei Hospital, Komono, Japan
J Cardiovasc Pharmacol 49:191-6. 2007..Administering carvedilol may improve the prognosis in this population... - Impact of lipid profile and high blood pressure on endothelial damageTomonori Sugiura
Department of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
J Clin Lipidol 5:460-6. 2011..We investigated the impact of lipid profiles and high blood pressure on damage... - Pioglitazone produces rapid and persistent reduction of vascular inflammation in patients with hypertension and type 2 diabetes mellitus who are receiving angiotensin II receptor blockersHiroyuki Takase
Department of Internal Medicine, Enshu General Hospital, Hamamatsu 430 0917, and Internal Medicine and Molecular Science, Graduate School of Medical Sciences, Nagoya City University, Japan
Metabolism 56:559-64. 2007..This may contribute to the reduction of cardiovascular events in this at-risk population... - Brachial-ankle pulse wave velocity predicts increase in blood pressure and onset of hypertensionHiroyuki Takase
Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan
Am J Hypertens 24:667-73. 2011..The present study was designed to test the hypothesis that brachial-ankle pulse wave velocity (baPWV) predicts longitudinal increases in blood pressure (BP) and new onset of hypertension in individuals with normal BP... - Nifedipine improves endothelial function: role of endothelial progenitor cellsTomonori Sugiura
Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Hypertension 52:491-8. 2008..These results demonstrate that nifedipine preserves endothelial integrity in patients with hypertension, at least partly, by enhancing EPC numbers and activity... - Metabolic disorders predict development of hypertension in normotensive Japanese subjectsHiroyuki Takase
Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan
Hypertens Res 31:665-71. 2008..Prediction of the development of hypertension may lead to effective prevention of both hypertension and resulting cardiovascular diseases... - Evaluation of risk for incident hypertension using glomerular filtration rate in the normotensive general populationHiroyuki Takase
Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan
J Hypertens 30:505-12. 2012..The present study tested the hypothesis that glomerular filtration rate can predict the onset of hypertension in individuals with normal blood pressure in the general population... - Crucial role of kidney function in resistance to antihypertensive therapy in patients with diabetes mellitusMasayoshi Kojima
Department of Internal Medicine, Komono Kosei Hospital, Komono, Mie, Japan
J Hypertens 28:2323-8. 2010..Effective blood pressure (BP) control is difficult to achieve in diabetic patients. This study investigated factors that exacerbate resistance to antihypertensive medication in patients with diabetes... - Effects of atorvastatin on inflammation and oxidative stressMasaya Sugiyama
Internal Medicine and Molecular Science, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan
Heart Vessels 20:133-6. 2005..The extra-lipid effects are not attributable to the lipid-lowering effect of the statin, suggesting that the pleiotropic effects of atorvastatin are independent of its effects on the lipid profile... - Increased oxidative stress impairs endothelial modulation of contractions in arteries from spontaneously hypertensive ratsKoichi Miyagawa
Department of Internal Medicine, Nagoya Koseiin Geriatric Hospital, Nagoya, Japan
J Hypertens 25:415-21. 2007..The endothelium modulates vascular contractions. We investigated the effects of oxidative stress on endothelial modulation of contractions in hypertension... - Excessive blood pressure elevation upon awakening involves an exaggerated cardiac response to slight physical activity: a possible mechanism underlying the risk of 'morning surge'Yoshimasa Wakamatsu
Department of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Science, Nagoya, Aichi, Japan
Blood Press Monit 17:198-203. 2012..We hypothesize that individuals with such a blood pressure abnormality receive a cardiovascular overload, even from slight physical activities that are frequently undertaken in daily life... - Antihypertensive effects of long-acting calcium channel blockers on hemodialysis days--a randomized crossover trial between benidipine and nifedipine CRMasayoshi Kojima
Department of Internal Medicine, Komono Kosei Hospital, Komono, Japan
Nephron Clin Pract 97:c49-53. 2004..The stable depressor effects of benidipine even after hemodialysis may contribute to favorable control of blood pressure in this population... - Usefulness of Tc-99m methoxyisobutylisonitrile scintigraphy for evaluating congestive heart failureTomonori Sugiura
Department of Internal Medicine, Enshu General Hospital, Hamamatsu, and Department of Internal Medicine and Molecular Science, Graduate School of Medical Sciences, Nagoya City University, Japan
J Nucl Cardiol 13:64-8. 2006..545, P<.01). The WR of MIBI was correlated with that of MIBG (r=0.603, P<.01). CONCLUSIONS: MIBI scintigraphy is useful in evaluating the severity of congestive heart failure... - B-type natriuretic peptide levels and cardiovascular risk in patients with diastolic dysfunction on chronic haemodialysis: cross-sectional and observational studiesHiroyuki Takase
Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan
Nephrol Dial Transplant 26:683-90. 2011..In the present study, we tested the hypothesis that left ventricular diastolic dysfunction increases BNP levels and can predict cardiovascular events in patients on chronic haemodialysis without apparent cardiac disease... - Salt sensitivity and circadian rhythm of blood pressure: the keys to connect CKD with cardiovascular eventsGenjiro Kimura
Department of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Hypertens Res 33:515-20. 2010..Salt sensitivity and circadian rhythm of BP are the keys to understanding the connections between cardiovascular and renal complications... - Renal dysfunction impairs circadian variation of endothelial function in patients with essential hypertensionKoji Yamamoto
Department of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho ku, Nagoya, Japan
J Am Soc Hypertens 4:265-71. 2010..Nocturnal blood pressure is elevated, and evening endothelial function deteriorates in parallel with a decline in renal function in hypertensive patients... - Uric acid levels predict future development of chronic kidney diseaseHiroo Sonoda
Department of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Am J Nephrol 33:352-7. 2011..Increased uric acid levels are associated with kidney dysfunction. We tested the hypothesis that uric acid level predicts future development of chronic kidney disease (CKD) in the general population... - Effect of troglitazone on endothelial function in type 2 diabetic patientsHiroyuki Takase
Department of Internal Medicine, Enshu General Hospital, Hamamatsu, Japan
Arzneimittelforschung 52:34-8. 2002..These results suggest that troglitazone is a beneficial agent improving FPG and HbA1c levels in NIDDM patients, while its effects on serum lysoPC and NOx levels, at least for 12 weeks, seem to be minimal... - Temocapril, an Angiotensin converting enzyme inhibitor, ameliorates age-related increase in carotid arterial stiffness in normotensive subjectsKunihiko Hayashi
Department of Internal Medicine, Nagoya Kosein Hospital, Nagoya, Japan
Cardiology 106:190-4. 2006..600, p < 0.05). CONCLUSION: These results suggest that temocapril ameliorates the age-related increase in carotid arterial stiffness in healthy, normotensive elderly subjects... - Circulating levels of myocardial proteins predict future deterioration of congestive heart failureTomonori Sugiura
Department of Internal Medicine, Enshu General Hospital, Hamamatsu, Shizuoka, Japan
J Card Fail 11:504-9. 2005.... - Titration of telmisartan, but not addition of amlodipine, reduces urine albumin in diabetic patients treated with telmisartan-diureticMasayoshi Kojima
aDepartment of Internal Medicine, Komono Kosei Hospital, Komono, Mie bDepartment of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
J Hypertens 31:186-91. 2013.... - Effects of ezetimibe on visceral fat in the metabolic syndrome: a randomised controlled studyHiroyuki Takase
Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan Department of Cardio Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Eur J Clin Invest 42:1287-94. 2012..Conclusions  Ezetimibe reduces visceral fat with beneficial effects on adiponectin and insulin resistance in patients with metabolic syndrome, suggesting a new therapeutic approach in such patients... - Distribution of central blood pressure values estimated by Omron HEM-9000AI in the Japanese general populationHiroyuki Takase
Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan
Hypertens Res 36:50-7. 2013.... - Long-term effects of donepezil on P300 auditory event-related potentials in patients with Alzheimer's diseaseEiichi Katada
Department of Internal Medicine, Nagoya City Johoku Hospital, Nagoya, Japan
J Geriatr Psychiatry Neurol 16:39-43. 2003..P300 latency gives very useful information on the progression of AD, especially in the longitudinal follow-up of patients with AD during treatment with DPZ acting on cholinergic pathways... - Effect of nifedipine on C-reactive protein levels in the coronary sinus and on coronary blood flow in response to acetylcholine in patients with stable angina pectoris having percutaneous coronary interventionHiroyuki Takase
Department of Internal Medicine, Enshu General Hospital, Hamamatsu
Am J Cardiol 95:1235-7. 2005..07 +/- 0.01 mg/dl, mean +/- SEM, p <0.05) and enhanced acetylcholine-induced increases in coronary blood flow. Thus, nifedipine is effective in decreasing inflammation and incresing endothelial function in the coronary circulation... - A case of reversible dilated cardiomyopathy after alpha-interferon therapy in a patient with renal cell carcinomaAkiko Kuwata
Second Department of Internal Medicine, Nagoya City University Medical School, Mizuho-ku, Nagoya 467-8601, Japan
Am J Med Sci 324:331-4. 2002..This is a rare case of interferon-induced cardiomyopathy that resulted in normal myocardial images in 123I-BMIPP and 123I-MIBG scintigrams after withdrawal of interferon therapy...