Noboru Takamura

Summary

Affiliation: Nagasaki University
Country: Japan

Publications

  1. doi request reprint Thyroid function is associated with carotid intima-media thickness in euthyroid subjects
    Noboru Takamura
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 8528523, Japan
    Atherosclerosis 204:e77-81. 2009
  2. pmc Evaluation of environmental contamination and estimated radiation doses for the return to residents' homes in Kawauchi Village, Fukushima prefecture
    Yasuyuki Taira
    Department of Global Health, Medical and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    PLoS ONE 7:e45816. 2012
  3. pmc Vertical distribution and estimated doses from artificial radionuclides in soil samples around the Chernobyl nuclear power plant and the Semipalatinsk nuclear testing site
    Yasuyuki Taira
    Department of Global Health, Medical and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    PLoS ONE 8:e57524. 2013
  4. ncbi request reprint Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer
    Ainur Akilzhanova
    Professor and Chairman, Department of Global Health, Medicine and Welfare, Atomic Bomb Disease Institute, Nagasaki University, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Anticancer Res 33:4049-59. 2013
  5. ncbi request reprint Lessons from Chernobyl
    Noboru Takamura
    Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
    Fukushima J Med Sci 57:81-5. 2011
  6. ncbi request reprint Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese
    Noboru Takamura
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Asia Pac J Clin Nutr 16:698-703. 2007
  7. doi request reprint Leptin to high-molecular-weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women
    Noboru Takamura
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Biomarkers 15:340-4. 2010
  8. ncbi request reprint White blood cell count and cardiovascular biomarkers of atherosclerosis
    Yui Sekitani
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Biomarkers 15:454-60. 2010
  9. doi request reprint Association of arterial stiffness and diabetes with triglycerides-to-HDL cholesterol ratio for Japanese men: the Nagasaki Islands Study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Atherosclerosis 228:491-5. 2013
  10. ncbi request reprint Influence of work duration or physical symptoms on mental health among Japanese visual display terminal users
    Zhaojia Ye
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
    Ind Health 45:328-33. 2007

Collaborators

Detail Information

Publications72

  1. doi request reprint Thyroid function is associated with carotid intima-media thickness in euthyroid subjects
    Noboru Takamura
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 8528523, Japan
    Atherosclerosis 204:e77-81. 2009
    ..We have demonstrated that carotid intima-media thickness is independently associated with thyroid function within the normal reference range, which suggests an increased cardiovascular risk in subjects with low normal thyroid function...
  2. pmc Evaluation of environmental contamination and estimated radiation doses for the return to residents' homes in Kawauchi Village, Fukushima prefecture
    Yasuyuki Taira
    Department of Global Health, Medical and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    PLoS ONE 7:e45816. 2012
    ..The case of Kawauchi Village will be the first model for the return to residents' homes after the FNPP accident...
  3. pmc Vertical distribution and estimated doses from artificial radionuclides in soil samples around the Chernobyl nuclear power plant and the Semipalatinsk nuclear testing site
    Yasuyuki Taira
    Department of Global Health, Medical and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    PLoS ONE 8:e57524. 2013
    ....
  4. ncbi request reprint Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer
    Ainur Akilzhanova
    Professor and Chairman, Department of Global Health, Medicine and Welfare, Atomic Bomb Disease Institute, Nagasaki University, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Anticancer Res 33:4049-59. 2013
    ..To analyze associations between homocysteine level, MTHFR and FTO rs1477196 polymorphisms and folate status in patients with breast cancer (BC) in order to clarify determinants of hyperhomocysteinemia...
  5. ncbi request reprint Lessons from Chernobyl
    Noboru Takamura
    Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
    Fukushima J Med Sci 57:81-5. 2011
    ..In this paper, we would like to summarize the impacts on the health of the people in Chernobyl compared to those caused by the accident at the Fukushima Daiichi Nuclear Power Plant...
  6. ncbi request reprint Determinants of plasma homocysteine levels and carotid intima-media thickness in Japanese
    Noboru Takamura
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Asia Pac J Clin Nutr 16:698-703. 2007
    ..001, p < 0.01). Our current results support previous findings that in addition to age and sex, serum creatinine and systolic blood pressure are independent determinants of homocysteine and carotid intima-media thickness, respectively...
  7. doi request reprint Leptin to high-molecular-weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women
    Noboru Takamura
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Biomarkers 15:340-4. 2010
    ..The leptin:adiponectin ratio (L:A ratio) is an independent predictor of carotid intima-media thickness (CIMT)...
  8. ncbi request reprint White blood cell count and cardiovascular biomarkers of atherosclerosis
    Yui Sekitani
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Biomarkers 15:454-60. 2010
    ..To investigate the association with white blood cells (WBC) and atherosclerotic parameters including cardio-ankle vascular index (CAVI) and carotid intima-media thickness (CIMT) in the general population...
  9. doi request reprint Association of arterial stiffness and diabetes with triglycerides-to-HDL cholesterol ratio for Japanese men: the Nagasaki Islands Study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Atherosclerosis 228:491-5. 2013
    ..To investigate this association, we conducted a cross-sectional study of 1344 Japanese men aged 36-79 years undergoing a general health check...
  10. ncbi request reprint Influence of work duration or physical symptoms on mental health among Japanese visual display terminal users
    Zhaojia Ye
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
    Ind Health 45:328-33. 2007
    ..1). In conclusion, the management of physical health as well as work duration is important for good mental health status among VDT users...
  11. ncbi request reprint Availability of cardio-ankle vascular index (CAVI) as a screening tool for atherosclerosis
    Koichiro Kadota
    Department of General Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Circ J 72:304-8. 2008
    ..A novel index, the cardio-ankle vascular index (CAVI), which reflects the stiffness of the aorta, femoral artery, and tibial artery, was recently developed by measuring brachial - ankle pulse wave velocity and blood pressure...
  12. ncbi request reprint Evaluation of cardiovascular risk factors and related clinical markers in healthy young Japanese adults
    Chiaki Yagura
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Clin Chem Lab Med 45:220-5. 2007
    ..Since atherosclerosis is a slowly progressive process at a young age, effective preventive measures should be taken early in life to prevent future events associated with cardiovascular disease...
  13. ncbi request reprint Free thyroxine (FT4) and anemia in relation to drinking status of Japanese men: the Nagasaki islands study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
    Endocr J 60:1029-34. 2013
    ..59 (0.41-0.85) for non-drinkers, and 1.23 (0.83-1.83) for drinkers. In conclusion, FT4 is inversely associated with anemia for non-drinking but not for drinking men. However, drinking may act as a confounding factor for this association. ..
  14. doi request reprint Association of periodontitis with carotid artery intima-media thickness and arterial stiffness in community-dwelling people in Japan: the Nagasaki Islands study
    Hideaki Hayashida
    Department of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, Japan
    Atherosclerosis 229:186-91. 2013
    ..The purpose of this study was to examine associations between periodontal status and carotid intima-media thickness (cIMT) and arterial stiffness using the cardio-ankle vascular index (CAVI) in community dwellers...
  15. ncbi request reprint Relationship between adult height and body weight and risk of carotid atherosclerosis assessed in terms of carotid intima-media thickness: the Nagasaki Islands study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
    J Physiol Anthropol 32:19. 2013
    ..Further, although the association between atherosclerosis and body mass index (BMI) is reportedly positive, there have been no reports of studies on associations between height and atherosclerosis in relation to BMI...
  16. ncbi request reprint Multimers and adiponectin gene 276G>T polymorphism in the Japanese population residing in rural areas
    Kiyomi Ishibashi
    Department of Island and Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Clin Chem Lab Med 45:1457-63. 2007
    ....
  17. ncbi request reprint Determinants of self-rated health among community-dwelling women aged 40 years and over in Japan
    Mitsuo Kanagae
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Japan
    Tohoku J Exp Med 210:11-9. 2006
    ..The determinants of self-rated health were similar in both middle-aged and elderly Japanese women. Our results could contribute to effective interventions to improve quality of life among Japanese women...
  18. ncbi request reprint Current concentration of artificial radionuclides and estimated radiation doses from 137Cs around the Chernobyl Nuclear Power Plant, the Semipalatinsk Nuclear Testing Site, and in Nagasaki
    Yasuyuki Taira
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    J Radiat Res 52:88-95. 2011
    ....
  19. ncbi request reprint Iodine prophylaxis around the Semipalatinsk Nuclear Testing Site, Republic of Kazakstan
    Aiko Hamada
    Department of International Health and Radiation Research, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Public Health Nutr 6:785-9. 2003
    ..This study aimed to clarify the iodine deficiency status in the Semipalatinsk region that has been contaminated by radioactive fallout from nuclear testing during the period of the former USSR...
  20. ncbi request reprint Evaluation of clinical markers of atherosclerosis in young and elderly Japanese adults
    Takanobu Hara
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Clin Chem Lab Med 44:824-9. 2006
    ..In order to be able to take preventative measures early in life against the development of atherosclerosis, it is important to evaluate profiles of subclinical atherosclerosis, especially among young adults...
  21. doi request reprint Factors predicting health-related quality of life in knee osteoarthritis among community-dwelling women in Japan: the Hizen-Oshima study
    Takahiro Norimatsu
    Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Orthopedics 34:e535-40. 2011
    ..These findings suggest that treating knee osteoarthritis and comorbidities, managing pain, and optimizing lower extremity muscle strength may be effective targets for intervention...
  22. doi request reprint Environmental contamination and external radiation dose rates from radionuclides released from the Fukushima Nuclear Power Plant
    Yasuyuki Taira
    Department of Global Health, Medical, and Welfare, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Radiat Prot Dosimetry 151:537-45. 2012
    ..Long-term environmental monitoring around FNPP contributes to radiation safety, with a reduction in unnecessary exposure to the residents...
  23. pmc Association between alkaline phosphatase and hypertension in a rural Japanese population: the Nagasaki Islands study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
    J Physiol Anthropol 32:10. 2013
    ....
  24. ncbi request reprint RET oncogene amplification in thyroid cancer: correlations with radiation-associated and high-grade malignancy
    Masahiro Nakashima
    Tissue and Histopathology Section, Division of Scientific Data Registry, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8523, Japan
    Hum Pathol 38:621-8. 2007
    ..RET amplification might be induced by a high level of genomic instability in connection with progression of thyroid carcinogenesis and, subsequently, be associated with radiation-induced and/or high-grade malignant cases...
  25. doi request reprint Factors associated with radiographic osteoarthritis of the knee among community-dwelling Japanese women: the Hizen-Oshima Study
    Takeshi Hashikawa
    Department of Orthopaedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, 852 8501, Japan
    J Orthop Sci 16:51-5. 2011
    ..We examine the risk factors for OA of the knee among Japanese community-dwelling women aged 40-89 years (mean age 64.2, SD 9.6 years)...
  26. doi request reprint Relation of body mass index to blood folate and total homocysteine concentrations in Japanese adults
    Mio Nakazato
    Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Eur J Nutr 50:581-5. 2011
    ..Our objective was to evaluate the association of BMI with blood folate and total homocysteine (tHcy) concentrations...
  27. ncbi request reprint Cyclin D1 overexpression in thyroid tumours from a radio-contaminated area and its correlation with Pin1 and aberrant beta-catenin expression
    Masahiro Nakashima
    Tissue and Histopathology Section, Division of Scientific Data Registry, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
    J Pathol 202:446-55. 2004
    ..Pin1 may be an important factor in regulating cyclin D1 and beta-catenin expression during thyroid carcinogenesis...
  28. ncbi request reprint Association between hemoglobin and diabetes in relation to the triglycerides-to-high-density lipoprotein cholesterol (TG-HDL) ratio in Japanese individuals: the Nagasaki Islands Study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Japan
    Intern Med 53:837-43. 2014
    ..In order to investigate these associations, we conducted a cross-sectional study of 3,733 (1,299 men and 2,434 women) Japanese participants 30-89 years of age undergoing a general health checkup...
  29. ncbi request reprint Good stress management capability is associated with lower body mass index and restful sleep in the elderly
    Seitaro Teraoka
    Department of Global Health, Medicine and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, Japan
    Tohoku J Exp Med 229:5-10. 2013
    ..If the ability to cope with psychosocial stress is important to the prevention of CVD, then weight control and proper sleep habits must be emphasized from a psychosocial stress-management perspective as well as a physical one...
  30. pmc Associations between renal impairment and anemia in older, rural Japanese men: the Nagasaki Island study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
    J Physiol Anthropol 33:7. 2014
    ..In addition, renal impairment is known to be associated with a form of anemia known as renal anemia...
  31. ncbi request reprint Urinary iodine concentrations in urban and rural areas around Chernobyl Nuclear Power Plant
    Yasuyuki Taira
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Endocr J 56:257-61. 2009
    ..These results suggest that the state of iodine supplementation has improved in rural areas, as well as in urban areas in the Republic of Belarus, probably due to appropriate fortification of iodized salt in this region...
  32. doi request reprint Determinants of the return to hometowns after the accident at Fukushima Dai-ichi nuclear power plant: a case study for the village of Kawauchi
    Makiko Orita
    Department of Global Health, Medical and Welfare, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Radiat Prot Dosimetry 156:383-5. 2013
    ..Results of this study suggest the importance of active participation by scientists and local authorities in communicating the risk to the general population involved in returning home. ..
  33. doi request reprint Evaluation of (137)Cs body burden in inhabitants of Bryansk Oblast, Russian Federation, where a high incidence of thyroid cancer was observed after the accident at the Chernobyl nuclear power plant
    Yui Sekitani
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8523, Japan
    Radiat Prot Dosimetry 141:36-42. 2010
    ..Because of the long half-life of (137)Cs, the long-term follow-up is necessary to monitor the health status and relieve the anxiety of the inhabitants around Chernobyl...
  34. ncbi request reprint Screening for 137Cs body burden due to the Chernobyl accident in Korosten City, Zhitomir, Ukraine: 1996-2008
    Naomi Hayashida
    Department of Global Health, Medicine and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Japan
    J Radiat Res 52:629-33. 2011
    ..Although the health effects of (137)Cs body burden due to the Chernobyl accident remain uncertain, further screening is needed to monitor the health status and to allay the anxiety of inhabitants in the contaminated areas around CNPP...
  35. ncbi request reprint Association between the hemoglobin levels and hypertension in relation to the BMI status in a rural Japanese population: the Nagasaki Islands Study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Japan
    Intern Med 53:435-40. 2014
    ..However, no published studies have examined this association in relation to the BMI status. The primary purpose of this study was to assess the association between the hemoglobin levels and hypertension in relation to the BMI status...
  36. ncbi request reprint Evaluation of high sensitive C-reactive protein and 5-10 methylenetetrahydrofolate reductase genotype in japanese young adults
    Yuko Kimura
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Biomarkers 9:291-7. 2004
    ..To carry out a preliminary evaluation of subclinical inflammation and its genetic background in young adults...
  37. ncbi request reprint Loss of heterozygosity on chromosome 9q22.3 in microdissected basal cell carcinomas around the Semipalatinsk Nuclear Testing Site, Kazakhstan
    Kenji Iwata
    Atomic Bomb Disease Institute, Nagasaki University School of Medicine, Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Hum Pathol 35:460-4. 2004
    ..03). The higher incidence of LOH on 9q22.3 in BCC from around SNTS suggests involvement of chronic low-dose irradiation by fallout from the test site as a factor in the cancers...
  38. ncbi request reprint Urinary iodine concentrations of pregnant women in Ukraine
    Yui Sekitani
    Department of Global Health, Medicine and Welfare, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 8528523, Japan
    Clin Chem Lab Med 51:811-6. 2013
    ..We examined the urinary iodine (UI) concentrations of pregnant women in Ukraine, where the iodine status is showing improvement among the general population...
  39. ncbi request reprint Urinary iodine kinetics after oral loading of potassium iodine
    Noboru Takamura
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Japan
    Endocr J 50:589-93. 2003
    ..Finally, we emphasized that the approach from social medicine is definitely important to establish an effective iodine prophylaxis...
  40. doi request reprint Assessment of internal exposure doses in Fukushima by a whole body counter within one month after the nuclear power plant accident
    Naoki Matsuda
    Center for Frontier Life Sciences, Nagasaki University, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Radiat Res 179:663-8. 2013
    ....
  41. ncbi request reprint Obesity and cardiovascular risk factors among men and women aged 40 years and older in a rural area of Japan
    Kiyoshi Aoyagi
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
    J Physiol Anthropol 25:371-5. 2006
    ..06) and dyslipidemia (p=0.01). These results emphasize the importance of preventing obesity in Japan. Therefore, healthcare professionals should measure BMI and WC in order to enhance their assessment of cardiovascular risk...
  42. ncbi request reprint Relationship between falls and physical performance measures among community-dwelling elderly women in Japan
    Masaharu Morita
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Aging Clin Exp Res 17:211-6. 2005
    ..It is important to clarify the relationship between falls and physical performance among the community-dwelling elderly...
  43. ncbi request reprint Thyroid blockade during a radiation emergency in iodine-rich areas: effect of a stable-iodine dosage
    Noboru Takamura
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Japan
    J Radiat Res 45:201-4. 2004
    ....
  44. ncbi request reprint Secular trends of sizes at birth in Japanese healthy infants born between 1962 and 1988
    Kazuyo Oishi
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Japan
    J Physiol Anthropol Appl Human Sci 23:155-61. 2004
    ..Size at birth was likely to increase from the '60s to '70s in Japan. These findings suggest that the environmental changes such as socioeconomic improvements influence the prenatal growth...
  45. ncbi request reprint Suitability of tartrate-resistant acid phosphatase type 5b as a screening marker for bone mineral density in community-dwelling elderly individuals
    Sumiko Irie
    Department of Global Health, Medicine and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Tohoku J Exp Med 224:105-10. 2011
    ..Because measurement of TRAP-5b is not affected by food intake, and blood samples can be collected at any time of the day, we suggest the suitability of serum TRAP-5b as a simple marker for the evaluation of BMD in women...
  46. ncbi request reprint Abnormal folic acid-homocysteine metabolism as maternal risk factors for Down syndrome in Japan
    Noboru Takamura
    Dept of Public Health, Nagasaki University, Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Eur J Nutr 43:285-7. 2004
    ..This food style may contribute to the occurrence of Down syndrome, which has proved to be linked to abnormal folate and homocysteine metabolisms...
  47. ncbi request reprint Correlation of cytoplasmic beta-catenin and cyclin D1 overexpression during thyroid carcinogenesis around Semipalatinsk nuclear test site
    Serik Meirmanov
    Department of Molecular Pathology, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
    Thyroid 13:537-45. 2003
    ..The analysis of the alteration of the Wnt signaling-related molecules in thyroid cancer around the SNTS may be important to gain an insight into radiation-induced thyroid tumorigenesis...
  48. ncbi request reprint The A>T polymorphism of the tribbles homolog 1 gene is associated with serum triglyceride concentrations in Japanese community-dwelling women
    Toshiyuki Ikeoka
    Department of Global Health, Medicine and Welfare, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences
    Tohoku J Exp Med 233:149-53. 2014
    ..004). On the other hand, there were no associations with CIMT and CAVI among the TRIB1 rs2954029 genotypes. In conclusion, the TRIB1 rs2954029 is associated with serum TG concentrations in Japanese community-dwelling women. ..
  49. ncbi request reprint Quantitation of sulfur-containing amino acids, homocysteine, methionine and cysteine in dried blood spot from newborn baby by HPLC-fluorescence detection
    Mitsuhiro Wada
    Graduate School of Biomedical Sciences, Nagasaki University, 1 14 Bunkyo machi, Nagasaki, 852 8521, Japan
    Biomed Chromatogr 28:810-4. 2014
    ..7%) were acceptable. The reliability of a dried blood spot as an analytical sample was estimated. Furthermore, the proposed method was successfully applied to dried blood spots prepared from newborn babies...
  50. ncbi request reprint Evaluation of environmental contamination and estimated exposure doses after residents return home in kawauchi village, fukushima prefecture
    Yasuyuki Taira
    Department of Global Health, Medicine and Welfare, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan
    Environ Sci Technol 48:4556-63. 2014
    ..Residents who have not yet returned may be able to return to their homes with a long-term follow-up of environmental monitoring and countermeasures to reduce unnecessary radiation exposure. ..
  51. ncbi request reprint The influence of visual display terminal use on the physical and mental conditions of administrative staff in Japan
    Zhaojia Ye
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Japan
    J Physiol Anthropol 26:69-73. 2007
    ..In order to protect users from the adverse effects associated with VDT work, reducing daily VDT exposure, taking breaks, and rest during VDT work are important...
  52. ncbi request reprint Depressive symptoms in Chinese factory workers in Nagasaki, Japan
    Yutaka Date
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8523, Japan
    Ind Health 47:376-82. 2009
    ..Further, we found that older age (30-49 yr) was marginally associated with high CES-D score. Health administration considering working time and age would be important for decreasing depressive symptoms among foreign workers...
  53. ncbi request reprint Urinary iodine concentrations in the high background radiation areas of Kanyakumari district, Tamilnadu, India
    Gopalganapathi M Brahmanandhan
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Endocr J 57:87-91. 2010
    ..Further screening, including morphological and functional analysis of the thyroid gland, will be needed to clarify the health effects of chronic low-dose radiation exposure attributable to residing in a high background radiation area...
  54. doi request reprint A validated HPLC-fluorescence method with a semi-micro column for routine determination of homocysteine, cysteine and cysteamine, and the relation between the thiol derivatives in normal human plasma
    Saori Ichinose
    Graduate School of Biomedical Sciences, Nagasaki University, 1 14 Bunkyo machi, Nagasaki, Japan
    Biomed Chromatogr 23:935-9. 2009
    ..As an application of the proposed method, the determination of thiol derivatives in normal human plasma (n = 103) was demonstrated. The correlation coefficients between Hcy vs Cys and Hcy vs CA were 0.38 and -0.35, respectively...
  55. doi request reprint Subclinical carotid atherosclerosis and hyperuricemia in relation to renal impairment in a rural Japanese population: the Nagasaki Islands study
    Yuji Shimizu
    Department of Community Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan Electronic address
    Atherosclerosis 233:525-9. 2014
    ..1 mm and the other with maximum CIMT≥1.1 mm. However, no studies have been reported of the association between hyperuricemia and subclinical carotid atherosclerosis while taking the two different ways of classification into account...
  56. doi request reprint Simultaneous determination of homocysteine, methionine and cysteine in maternal plasma after delivery by HPLC-fluorescence detection with DBD-F as a label
    Mitsuhiro Wada
    Graduate School of Biomedical Sciences, Nagasaki University, 1 14 Bunkyo machi, Nagasaki, 852 8521, Japan
    Biomed Chromatogr 27:708-13. 2013
    ..The concentrations of Hcy, Met and Cys as a median (inter quartile range, Q1 and Q3 ) were 5.37 (3.32-7.79) μm, 25.20 (20.10-31.06) μm and 147.25 (102.81-189.31) μm, respectively...
  57. doi request reprint Importance of personal dose equivalent evaluation in Fukushima in overcoming social panic
    Kohji Yoshida
    Department of Global Health, Medicine and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Radiat Prot Dosimetry 151:144-6. 2012
    ..0538. The preliminary data of this study show that, in Fukushima, the individual dose is much lower than that determined H*(10). It is important to evaluate H(p)(10) in order to lessen the anxiety of the general population in Fukushima...
  58. ncbi request reprint Effects of lifestyle factors on stiffness index of calcaneus measured by quantitative ultrasound system among Japanese women aged 40 years and over: the Hizen-Oshima Study
    Yong Zhang
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8523, Japan
    Tohoku J Exp Med 201:97-107. 2003
    ..In conclusion, higher physical activity, in combination with adequate nutrition for weight maintenance, should be emphasized as a part of a healthy lifestyle in order to maintain bone health among middle-aged and elderly Japanese women...
  59. pmc Prognosis of thyroid nodules in individuals living in the Zhitomir region of Ukraine
    Naomi Hayashida
    Department of Global Health, Medicine and Welfare, Nagasaki University, Nagasaki, Japan
    PLoS ONE 7:e50648. 2012
    ..To assess the prognosis of benign thyroid nodules in individuals living in the Zhitomir region of Ukraine, around the CNPP, we conducted a follow-up investigation of screening data from 1991 to 2000 in the Ukraine...
  60. ncbi request reprint Poor chewing ability is associated with lower mucosal moisture in elderly individuals
    Tetsuko Shinkawa
    Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Tohoku J Exp Med 219:263-7. 2009
    ..70, p = 0.016), and anemia (OR: 1.96, p = 0.030) were significantly associated with self-assessed chewing ability. Our current study indicates that poor chewing ability is associated with lower mucosal moisture in elderly individuals...
  61. ncbi request reprint Self-perceived oral health status and influencing factors of the elderly residents of a peri-urban area of La Paz, Bolivia
    Juan Ugarte
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
    Int Dent J 57:19-26. 2007
    ..To assess the self-perceived oral health status of the elderly in Bolivia and explore the relationship between the socio-demographic and subjective factors that influence such perception...
  62. doi request reprint Relationship between periodontal status and HbA1c in nondiabetics
    Hideaki Hayashida
    Department of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8588, Japan
    J Public Health Dent 69:204-6. 2009
    ..We analyzed the periodontal status and glycosylated hemoglobin (HbA1c) level in nondiabetic subjects to investigate the relationship between periodontitis and glucose control in nondiabetics...
  63. ncbi request reprint Body mass index correlated with forced expiratory volume in 1 second/forced vital capacity in a population with a relatively low prevalence of obesity
    Susumu Fukahori
    Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, Japan
    Chin Med J (Engl) 123:2792-6. 2010
    ..We measured BMI and performed spirometry on screening patients who had consulted general clinics...
  64. ncbi request reprint PET/CT shows subjective pain in shoulder joints to be associated with uptake of (18)F-FDG
    Toshihiko Kamasaki
    Departments of aGlobal Health, Medicine and Welfare bRadioisotope Medicine, Atomic Bomb Disease Institute, Nagasaki University cDepartment of Rehabilitation, Nishi Isahaya Hospital dNishi Isahaya Hospital PET CT Diagnostic Imaging Center, Nagasaki, Japan
    Nucl Med Commun 35:44-50. 2014
    ..The aim of the study was to evaluate the capability of fluorine-18-fluorodeoxyglucose (F-FDG)-positron emission tomography (PET)/computed tomography (CT) in the screening of musculoskeletal inflammation and injury of the shoulder region...
  65. ncbi request reprint No evidence of radiation risk for thyroid gland among schoolchildren around Semipalatinsk Nuclear Testing Site
    Aiko Hamada
    Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University School of Medicine, Nagasaki 852 8523, Japan
    Endocr J 50:85-9. 2003
    ..These results suggest that there is no transgenerational risk for schoolchildren born from parents irradiated as a result of tests carried out in SNTS...
  66. ncbi request reprint Pilot study on the use of tourniquet: a risk factor for pulmonary thromboembolism after total knee arthroplasty?
    Masahiko Nishiguchi
    Department of Orthopaedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Thromb Res 115:271-6. 2005
    ..The results of our pilot study showed that elevated plasma "D1 value" is a sensitive marker for detection of PTE. Further studies will be needed, in order to evaluate the risk of tourniquet, and to reduce PTE after TKA...
  67. ncbi request reprint Plasma concentrations of adrenomedullin and ghrelin in hemodialysis patients with sustained and episodic hypotension
    Kikuko Iwanaga
    Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
    Endocr J 52:23-8. 2005
    ..Further studies are necessary to clarify the implication of these hormones in the control of hypotension during HD...
  68. ncbi request reprint The possibility of a valuable resource of circulating DNA for single nucleotide polymorphisms genotyping: the application of a rapid and simple polymerase chain reaction with melting curve analysis for methyltetrahydrofolate reductase polymorphisms
    Sayaka Mori
    Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences and Central Diagnostic Laboratory, Nagasaki University Hospital, Nagasaki, Japan
    Lab Hematol 13:1-5. 2007
    ..Circulating DNA from storage plasma is acceptable for genetic tests, but it is necessary to note the integrity of DNA...
  69. doi request reprint Background radiation and individual dosimetry in the costal area of Tamil Nadu, India
    Naoki Matsuda
    Center for Frontier Life Sciences, Nagasaki University, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Radiat Prot Dosimetry 146:314-7. 2011
    ..7 Bq g(-1) of Th-228. The individual dose of five inhabitants in Chinnavillai, as measured by the radiophotoluminescence glass dosimetry system, demonstrated the average dose of 7.17 mSv y(-1) ranging from 2.79 to 14.17 mSv y(-1)...
  70. ncbi request reprint Monitoring the autonomic nervous activity as the objective evaluation of music therapy for severely and multiply disabled children
    Makiko Orita
    Departments of Global Health, Medicine and Welfare, Nagasaki University Graduate School of Biomedical Sciences, Japan
    Tohoku J Exp Med 227:185-9. 2012
    ..The monitoring changes in the autonomic nervous activities could be a powerful tool for the objective evaluation of music therapy in patients with SMDC...
  71. ncbi request reprint Evaluation of fat-free mass by whole-body counter in Japanese healthy young adults
    Naoko Morita
    Department of Radiation Biophysics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
    Radiat Prot Dosimetry 123:128-30. 2007
    ..Multiple linear regression analysis, following adjustments for sex, indicates that only LBM has a significant correlation with TBK (P < 0.01). These results strongly support the feasibility of using WBCs for estimating FFM...
  72. ncbi request reprint Geographic distribution of the incidence of adult T-cell leukemia/lymphoma and other malignancies in nagasaki prefecture, Japan
    Kokichi Arisawa
    Department of Preventive Medicine, Nagasaki University School of Medicine, Nagasaki, Japan
    Jpn J Clin Oncol 32:301-6. 2002
    ..It remains unclear whether human T-cell lymphotropic virus type-I (HTLV-I) infection is associated with an increased risk of malignancies other than adult T-cell leukemia/lymphoma...