Kiyonori Miura

Summary

Affiliation: Nagasaki University
Country: Japan

Publications

  1. ncbi request reprint A strong association between human earwax-type and apocrine colostrum secretion from the mammary gland
    Kiyonori Miura
    Department of Obstetrics and Gynaecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Hum Genet 121:631-3. 2007
  2. doi request reprint Identification of pregnancy-associated microRNAs in maternal plasma
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Clin Chem 56:1767-71. 2010
  3. doi request reprint Increased level of cell-free placental mRNA in a subgroup of placenta previa that needs hysterectomy
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Prenat Diagn 28:805-9. 2008
  4. doi request reprint Clinical application of fetal sex determination using cell-free fetal DNA in pregnant carriers of X-linked genetic disorders
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    J Hum Genet 56:296-9. 2011
  5. doi request reprint The possibility of microarray-based analysis using cell-free placental mRNA in maternal plasma
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Prenat Diagn 30:849-61. 2010
  6. doi request reprint A case of Kallmann syndrome carrying a missense mutation in alternatively spliced exon 8A encoding the immunoglobulin-like domain IIIb of fibroblast growth factor receptor 1
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, Japan
    Hum Reprod 25:1076-80. 2010
  7. doi request reprint Characterization of placenta-specific microRNAs in fetal growth restriction pregnancy
    Ai Higashijima
    Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Prenat Diagn 33:214-22. 2013
  8. doi request reprint Pre-vaccination epidemiology of human papillomavirus infections in Japanese women with abnormal cytology
    Kentaro Yamasaki
    Department of Obstetrics and Gynecology, School of Medicine, Nagasaki University, Sakamoto, Japan
    J Obstet Gynaecol Res 37:1666-70. 2011
  9. ncbi request reprint Microarray comparative genomic hybridization (CGH)-based prenatal diagnosis for chromosome abnormalities using cell-free fetal DNA in amniotic fluid
    Shoko Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1 7 1, 852 8501, Nagasaki, Japan
    J Hum Genet 51:412-7. 2006
  10. doi request reprint Does increased nuchal translucency indicate a fetal abnormality? A retrospective study to clarify the clinical significance of nuchal translucency in Japan
    Shigo Yoshida
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, 852 8501, Japan
    J Hum Genet 53:688-93. 2008

Collaborators

Detail Information

Publications32

  1. ncbi request reprint A strong association between human earwax-type and apocrine colostrum secretion from the mammary gland
    Kiyonori Miura
    Department of Obstetrics and Gynaecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Hum Genet 121:631-3. 2007
    ..0002), and the measurable colostrum volume in dry-type women was significantly smaller than in wet-type women (P=0.0341)...
  2. doi request reprint Identification of pregnancy-associated microRNAs in maternal plasma
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Clin Chem 56:1767-71. 2010
    ..Our understanding of these novel molecules is still limited, however. The aim of this study was to isolate and characterize pregnancy-associated miRNAs in maternal plasma...
  3. doi request reprint Increased level of cell-free placental mRNA in a subgroup of placenta previa that needs hysterectomy
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Prenat Diagn 28:805-9. 2008
    ..The purpose of this study was to investigate whether cell-free placental mRNA levels have the potential to predict a placenta previa resulting in hysterectomy...
  4. doi request reprint Clinical application of fetal sex determination using cell-free fetal DNA in pregnant carriers of X-linked genetic disorders
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    J Hum Genet 56:296-9. 2011
    ..This procedure could avoid unnecessary CVS in female fetuses...
  5. doi request reprint The possibility of microarray-based analysis using cell-free placental mRNA in maternal plasma
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Prenat Diagn 30:849-61. 2010
    ..The purpose of this study is to investigate a possibility of overall assessment of cell-free (CF) placental mRNAs in maternal plasma...
  6. doi request reprint A case of Kallmann syndrome carrying a missense mutation in alternatively spliced exon 8A encoding the immunoglobulin-like domain IIIb of fibroblast growth factor receptor 1
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, Japan
    Hum Reprod 25:1076-80. 2010
    ..Therefore, this is the first case of KS carrying a de novo missense mutation in FGFR1 exon 8A, suggesting that isoform FGFR1-IIIb, as well as isoform FGFR1-IIIc, plays a crucial role in the pathogenesis of KS...
  7. doi request reprint Characterization of placenta-specific microRNAs in fetal growth restriction pregnancy
    Ai Higashijima
    Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Prenat Diagn 33:214-22. 2013
    ..The aim of this study was to characterize placenta-specific microRNAs in fetal growth restriction (FGR) pregnancy...
  8. doi request reprint Pre-vaccination epidemiology of human papillomavirus infections in Japanese women with abnormal cytology
    Kentaro Yamasaki
    Department of Obstetrics and Gynecology, School of Medicine, Nagasaki University, Sakamoto, Japan
    J Obstet Gynaecol Res 37:1666-70. 2011
    ..To investigate the pre-vaccination epidemiology of genital human papillomavirus (HPV) infections and genotypes in women with abnormal cytology in Nagasaki, Japan...
  9. ncbi request reprint Microarray comparative genomic hybridization (CGH)-based prenatal diagnosis for chromosome abnormalities using cell-free fetal DNA in amniotic fluid
    Shoko Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1 7 1, 852 8501, Nagasaki, Japan
    J Hum Genet 51:412-7. 2006
    ....
  10. doi request reprint Does increased nuchal translucency indicate a fetal abnormality? A retrospective study to clarify the clinical significance of nuchal translucency in Japan
    Shigo Yoshida
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, 852 8501, Japan
    J Hum Genet 53:688-93. 2008
    ....
  11. doi request reprint Copy number variation of the antimicrobial-gene, defensin beta 4, is associated with susceptibility to cervical cancer
    Shuhei Abe
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    J Hum Genet 58:250-3. 2013
    ..33-0.74). We found copy number variation of DEFB4 was a host genetic factor conferring susceptibility to cervical cancer. A lower DEFB4 copy number was associated with susceptibility to cervical cancer...
  12. doi request reprint Epidemiology of human papillomavirus genotypes in pregnant Japanese women
    Kentaro Yamasaki
    Department of Obstetrics and Gynecology, School of Medicine, Nagasaki University, Nagasaki, Japan
    J Hum Genet 56:313-5. 2011
    ..Infection with multiple HPV genotypes was observed more frequently in the first trimester of pregnancy and the pattern of infection changed significantly depending on pregnancy stage...
  13. ncbi request reprint Clinical applications of plasma circulating mRNA analysis in cases of gestational trophoblastic disease
    Hideaki Masuzaki
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Clin Chem 51:1261-3. 2005
  14. doi request reprint Initial viral load in cases of single human papillomavirus 16 or 52 persistent infection is associated with progression of later cytopathological findings in the uterine cervix
    Daisuke Hamaguchi
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    J Med Virol 85:2093-100. 2013
    ..103 in the non-progression group (Pā€‰=ā€‰0.001). HPV 52 and 16 DNA loads assessed by quantitative real-time methods may be useful short-term markers for identifying women at high risk for progression of cervical cytological pathology...
  15. ncbi request reprint Clinical outcome of infants with confined placental mosaicism and intrauterine growth restriction of unknown cause
    Kiyonori Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Am J Med Genet A 140:1827-33. 2006
    ..8/15 infants without CPM), although no statistically significant difference was obtained. The information obtained will be useful for perinatal care and genetic counseling for infants with IUGR and CPM...
  16. ncbi request reprint Prenatal ultrasonographic findings may be useful in predicting the prognosis of trisomy 18
    Terumi Tanigawa
    Department of Obstetrics and Gynecology, Nagasaki University School of Medicine, Nagasaki, Japan
    Prenat Diagn 27:1039-44. 2007
    ..This study was conducted to determine whether specific ultrasonographic findings in the prenatal period were associated with survival of children affected with trisomy 18...
  17. ncbi request reprint Origin and mechanisms of formation of fetus-in-fetu: two cases with genotype and methylation analyses
    Shoko Miura
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Am J Med Genet A 140:1737-43. 2006
    ..This is the first case of FIF showing different methylation patterns between a host infant and fetiform mass...
  18. doi request reprint Human papillomavirus DNA in plasma of patients with HPV16 DNA-positive uterine cervical cancer
    Takako Shimada
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8501, Japan
    Jpn J Clin Oncol 40:420-4. 2010
    ....
  19. ncbi request reprint A monozygotic twin pregnancy discordant for acardia and X-inactivation pattern
    Hideaki Masuzaki
    Department of Obstetrics and Gynecology, Nagasaki University, Graduate School of Biomedical Sciences, Sakamoto 1 7 1, Nagasaki, Japan
    Eur J Obstet Gynecol Reprod Biol 117:102-4. 2004
    ....
  20. doi request reprint Management of prenatal ovarian cysts
    Takako Shimada
    Department of Obstetrics and Gynaecology, Nagasaki University Graduate, School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Early Hum Dev 84:417-20. 2008
    ..The aim of the present study was to analyze the antenatal and postnatal outcome of fetal ovarian cysts in relation to their ultrasonographic pattern and size...
  21. doi request reprint Giant cystic meconium peritonitis associated with a cloacal anomaly: case report
    Takayuki Hamada
    Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8501, Japan
    J Pediatr Surg 43:E21-3. 2008
    ..However, the present case showed a rare GCMP suggesting continuous urinary influx via the fallopian tubes until the later stage of intrauterine life...
  22. ncbi request reprint Genital human papilloma virus infection in mentally-institutionalized virgins
    Takako Shimada
    Department of Obstetrics and Gynecology, Nagasaki University Graduated School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, and Yasunaga Obstetrics and Gynecology Hospital, Isahaya, Japan
    Gynecol Oncol 106:488-9. 2007
    ..Risk factors for HPV infection are primarily related to sexual behavior. We determined the prevalence of HPV infection and abnormal cervical cytology in institutionalized women with no previous sexual experience...
  23. ncbi request reprint Effect of placenta previa on blood loss in second-trimester abortion by labor induction using gemeprost
    Daisuke Nakayama
    Department of Obstetrics and Gynecology, Nagasaki University Faculty of Medicine, Nagasaki 852 8501, Japan
    Contraception 75:238-40. 2007
    ..The study was conducted to determine whether placenta previa increases bleeding during gemeprost-induced termination of second-trimester pregnancy...
  24. ncbi request reprint Characterization of the human nasal embryonic LHRH factor gene, NELF, and a mutation screening among 65 patients with idiopathic hypogonadotropic hypogonadism (IHH)
    Kiyonori Miura
    Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    J Hum Genet 49:265-8. 2004
    ..Four other novel SNPs (102C > T and 1029C > T within the coding region, and two IVS14+47C > T and IVS15+41G > A) were also identified in NELF...
  25. doi request reprint Uniparental disomy analysis in trios using genome-wide SNP array and whole-genome sequencing data imply segmental uniparental isodisomy in general populations
    Kensaku Sasaki
    Department of Human Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Gene 512:267-74. 2013
    ..Based on the autosomal chromosome pairs investigated, we estimate the rate of segmental UPD to be one per 3806 chromosome pairs (0.026%). These data imply the possibility of hidden segmental UPD in normal individuals...
  26. ncbi request reprint Do monochorionic dizygotic twins increase after pregnancy by assisted reproductive technology?
    Kiyonori Miura
    Department of Obstetrics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    J Hum Genet 50:1-6. 2005
    ..This "chance hypothesis" can simply explain why MC DZT are very rare in natural pregnancy. Large-scale research on the prevalence of ART-associated MC DZT and long-term follow-up of the twins are essential...
  27. doi request reprint First case of liposarcoma arising from the fallopian tube: case report and review of the literature
    Hitomi Oishi
    Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
    J Obstet Gynaecol Res 34:713-6. 2008
    ..When a pelvic mass with fatty density that does not show typical findings of a mature cystic teratoma is detected by either CT or magnetic resonance imaging, the possibility of a liposarcoma should be considered...
  28. ncbi request reprint A monozygotic conjoined twin pregnancy discordant for laterality of cleft lip
    Hideaki Masuzaki
    Department of Obstetrics and Gynecology, Nagasaki University School of Medicine, Nagasaki, Japan
    Gynecol Obstet Invest 57:100-2. 2004
    ..Genotyping at 50 polymorphic loci revealed that the twins were identical (monozygotic). Our analysis suggests that the laterality of cleft lip is more affected by the process of twinning than by genetic factors...
  29. pmc The human ASCL2 gene escaping genomic imprinting and its expression pattern
    Toshinobu Miyamoto
    Department of Human Genetics, School of Medicine, Nagasaki University, Japan
    J Assist Reprod Genet 19:240-4. 2002
    ..In addition, it has been shown that the human ASCL2 gene escapes genomic imprinting...
  30. ncbi request reprint Placental mRNA in maternal plasma and its clinical application to the evaluation of placental status in a pregnant woman with placenta previa-percreta
    Hideaki Masuzaki
    Clin Chem 51:923-5. 2005
  31. ncbi request reprint Circulating cell-free placental mRNA in the maternal plasma as a predictive marker for twin-twin transfusion syndrome
    Kiyonori Miura
    Clin Chem 53:1167-8. 2007
  32. ncbi request reprint Complete hydatidiform mole and normal live birth following intracytoplasmic sperm injection
    Haruka Hamanoue
    Department of Human Genetics, Graduate School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, 236 0004, Japan
    J Hum Genet 51:477-9. 2006
    ..This is the second report of this condition and is accompanied by the first well-described molecular analysis...