Research Topics
Species | Kiyonori MiuraSummaryAffiliation: Nagasaki University Country: Japan Publications
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Detail Information
Publications
A case of Kallmann syndrome carrying a missense mutation in alternatively spliced exon 8A encoding the immunoglobulin-like domain IIIb of fibroblast growth factor receptor 1Kiyonori Miura
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, Japan
Hum Reprod 25:1076-80. 2010..Therefore, this is the first case of KS carrying a de novo missense mutation in FGFR1 exon 8A, suggesting that isoform FGFR1-IIIb, as well as isoform FGFR1-IIIc, plays a crucial role in the pathogenesis of KS...
Clinical application of fetal sex determination using cell-free fetal DNA in pregnant carriers of X-linked genetic disordersKiyonori Miura
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
J Hum Genet 56:296-9. 2011..This procedure could avoid unnecessary CVS in female fetuses...
Increased level of cell-free placental mRNA in a subgroup of placenta previa that needs hysterectomyKiyonori Miura
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Prenat Diagn 28:805-9. 2008..The purpose of this study was to investigate whether cell-free placental mRNA levels have the potential to predict a placenta previa resulting in hysterectomy...
Identification of pregnancy-associated microRNAs in maternal plasmaKiyonori Miura
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
Clin Chem 56:1767-71. 2010..Our understanding of these novel molecules is still limited, however. The aim of this study was to isolate and characterize pregnancy-associated miRNAs in maternal plasma...
The possibility of microarray-based analysis using cell-free placental mRNA in maternal plasmaKiyonori Miura
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Prenat Diagn 30:849-61. 2010..The purpose of this study is to investigate a possibility of overall assessment of cell-free (CF) placental mRNAs in maternal plasma...
A strong association between human earwax-type and apocrine colostrum secretion from the mammary glandKiyonori Miura
Department of Obstetrics and Gynaecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
Hum Genet 121:631-3. 2007..0002), and the measurable colostrum volume in dry-type women was significantly smaller than in wet-type women (P=0.0341)...
Pre-vaccination epidemiology of human papillomavirus infections in Japanese women with abnormal cytologyKentaro Yamasaki
Department of Obstetrics and Gynecology, School of Medicine, Nagasaki University, Sakamoto, Japan
J Obstet Gynaecol Res 37:1666-70. 2011..To investigate the pre-vaccination epidemiology of genital human papillomavirus (HPV) infections and genotypes in women with abnormal cytology in Nagasaki, Japan...
Microarray comparative genomic hybridization (CGH)-based prenatal diagnosis for chromosome abnormalities using cell-free fetal DNA in amniotic fluidShoko Miura
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, 852-8501, Nagasaki, Japan
J Hum Genet 51:412-7. 2006....
Clinical outcome of infants with confined placental mosaicism and intrauterine growth restriction of unknown causeKiyonori Miura
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Am J Med Genet A 140:1827-33. 2006..8/15 infants without CPM), although no statistically significant difference was obtained. The information obtained will be useful for perinatal care and genetic counseling for infants with IUGR and CPM...
Does increased nuchal translucency indicate a fetal abnormality? A retrospective study to clarify the clinical significance of nuchal translucency in JapanShigo Yoshida
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki, 852 8501, Japan
J Hum Genet 53:688-93. 2008....
Origin and mechanisms of formation of fetus-in-fetu: two cases with genotype and methylation analysesShoko Miura
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Am J Med Genet A 140:1737-43. 2006..This is the first case of FIF showing different methylation patterns between a host infant and fetiform mass...
Clinical applications of plasma circulating mRNA analysis in cases of gestational trophoblastic diseaseHideaki Masuzaki
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Clin Chem 51:1261-3. 2005
Epidemiology of human papillomavirus genotypes in pregnant Japanese womenKentaro Yamasaki
Department of Obstetrics and Gynecology, School of Medicine, Nagasaki University, Nagasaki, Japan
J Hum Genet 56:313-5. 2011..Infection with multiple HPV genotypes was observed more frequently in the first trimester of pregnancy and the pattern of infection changed significantly depending on pregnancy stage...
Characterization of placenta-specific microRNAs in fetal growth restriction pregnancyAi Higashijima
Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Prenat Diagn 33:214-22. 2013..The aim of this study was to characterize placenta-specific microRNAs in fetal growth restriction (FGR) pregnancy...
Human papillomavirus DNA in plasma of patients with HPV16 DNA-positive uterine cervical cancerTakako Shimada
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8501, Japan
Jpn J Clin Oncol 40:420-4. 2010....
Prenatal ultrasonographic findings may be useful in predicting the prognosis of trisomy 18Terumi Tanigawa
Department of Obstetrics and Gynecology, Nagasaki University School of Medicine, Nagasaki, Japan
Prenat Diagn 27:1039-44. 2007..This study was conducted to determine whether specific ultrasonographic findings in the prenatal period were associated with survival of children affected with trisomy 18...
A monozygotic twin pregnancy discordant for acardia and X-inactivation patternHideaki Masuzaki
Department of Obstetrics and Gynecology, Nagasaki University, Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, Japan
Eur J Obstet Gynecol Reprod Biol 117:102-4. 2004....
Management of prenatal ovarian cystsTakako Shimada
Department of Obstetrics and Gynaecology, Nagasaki University Graduate, School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
Early Hum Dev 84:417-20. 2008..The aim of the present study was to analyze the antenatal and postnatal outcome of fetal ovarian cysts in relation to their ultrasonographic pattern and size...
Genital human papilloma virus infection in mentally-institutionalized virginsTakako Shimada
Department of Obstetrics and Gynecology, Nagasaki University Graduated School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, and Yasunaga Obstetrics and Gynecology Hospital, Isahaya, Japan
Gynecol Oncol 106:488-9. 2007..Risk factors for HPV infection are primarily related to sexual behavior. We determined the prevalence of HPV infection and abnormal cervical cytology in institutionalized women with no previous sexual experience...
Giant cystic meconium peritonitis associated with a cloacal anomaly: case reportTakayuki Hamada
Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852 8501, Japan
J Pediatr Surg 43:E21-3. 2008..However, the present case showed a rare GCMP suggesting continuous urinary influx via the fallopian tubes until the later stage of intrauterine life...
Effect of placenta previa on blood loss in second-trimester abortion by labor induction using gemeprostDaisuke Nakayama
Department of Obstetrics and Gynecology, Nagasaki University Faculty of Medicine, Nagasaki 852 8501, Japan
Contraception 75:238-40. 2007..The study was conducted to determine whether placenta previa increases bleeding during gemeprost-induced termination of second-trimester pregnancy...
Characterization of the human nasal embryonic LHRH factor gene, NELF, and a mutation screening among 65 patients with idiopathic hypogonadotropic hypogonadism (IHH)Kiyonori Miura
Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, MA 02114, USA
J Hum Genet 49:265-8. 2004..Four other novel SNPs (102C > T and 1029C > T within the coding region, and two IVS14+47C > T and IVS15+41G > A) were also identified in NELF...
Uniparental disomy analysis in trios using genome-wide SNP array and whole-genome sequencing data imply segmental uniparental isodisomy in general populationsKensaku Sasaki
Department of Human Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Gene 512:267-74. 2013..Based on the autosomal chromosome pairs investigated, we estimate the rate of segmental UPD to be one per 3806 chromosome pairs (0.026%). These data imply the possibility of hidden segmental UPD in normal individuals...
Do monochorionic dizygotic twins increase after pregnancy by assisted reproductive technology?Kiyonori Miura
Department of Obstetrics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
J Hum Genet 50:1-6. 2005..This "chance hypothesis" can simply explain why MC DZT are very rare in natural pregnancy. Large-scale research on the prevalence of ART-associated MC DZT and long-term follow-up of the twins are essential...
First case of liposarcoma arising from the fallopian tube: case report and review of the literatureHitomi Oishi
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
J Obstet Gynaecol Res 34:713-6. 2008..When a pelvic mass with fatty density that does not show typical findings of a mature cystic teratoma is detected by either CT or magnetic resonance imaging, the possibility of a liposarcoma should be considered...
A monozygotic conjoined twin pregnancy discordant for laterality of cleft lipHideaki Masuzaki
Department of Obstetrics and Gynecology, Nagasaki University School of Medicine, Nagasaki, Japan
Gynecol Obstet Invest 57:100-2. 2004..Genotyping at 50 polymorphic loci revealed that the twins were identical (monozygotic). Our analysis suggests that the laterality of cleft lip is more affected by the process of twinning than by genetic factors...
The human ASCL2 gene escaping genomic imprinting and its expression patternToshinobu Miyamoto
Department of Human Genetics, School of Medicine, Nagasaki University, Japan
J Assist Reprod Genet 19:240-4. 2002..In addition, it has been shown that the human ASCL2 gene escapes genomic imprinting...
Complete hydatidiform mole and normal live birth following intracytoplasmic sperm injectionHaruka Hamanoue
Department of Human Genetics, Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan
J Hum Genet 51:477-9. 2006..This is the second report of this condition and is accompanied by the first well-described molecular analysis...
Circulating cell-free placental mRNA in the maternal plasma as a predictive marker for twin-twin transfusion syndromeKiyonori Miura
Clin Chem 53:1167-8. 2007
Placental mRNA in maternal plasma and its clinical application to the evaluation of placental status in a pregnant woman with placenta previa-percretaHideaki Masuzaki
Clin Chem 51:923-5. 2005
