Research Topics

Genomes and Genes


Daisuke Ishibashi


Affiliation: Nagasaki University
Country: Japan


  1. Ishibashi D, Nakagaki T, Ishikawa T, Atarashi R, Watanabe K, Cruz F, et al. Structure-Based Drug Discovery for Prion Disease Using a Novel Binding Simulation. EBioMedicine. 2016;9:238-249 pubmed publisher
    ..This NUDE-based structure-based drug discovery for normal protein structures is likely useful for the development of drugs to treat other conformational disorders, such as Alzheimer's disease. ..
  2. Ishibashi D, Atarashi R, Fuse T, Nakagaki T, Yamaguchi N, Satoh K, et al. Protective role of interferon regulatory factor 3-mediated signaling against prion infection. J Virol. 2012;86:4947-55 pubmed publisher
    ..Our findings provide new insight into the role of the host innate immune system in the pathogenesis of prion diseases. ..
  3. Ishibashi D, Atarashi R, Nishida N. Protective role of MyD88-independent innate immune responses against prion infection. Prion. 2012;6:443-6 pubmed publisher
    ..Although the mechanism for the anti-prion effects mediated by IRF3 has yet to be clarified, certain interferon responsive genes might be involved in the anti-prion host-defense mechanism. ..