Akira Funada

Summary

Affiliation: Nagasaki University
Country: Japan

Publications

  1. doi request reprint Late aneurysm formation of Valsalva sinus after aortic valve replacement due to Takayasu's arteritis
    Akira Funada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, 565 8565, Japan
    Heart Vessels 30:558-62. 2015
  2. doi request reprint Assessment of QT intervals and prevalence of short QT syndrome in Japan
    Akira Funada
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Clin Cardiol 31:270-4. 2008
  3. ncbi request reprint Three cases of iatrogenic coronary ostial stenosis after aortic valve replacement
    Akira Funada
    Fukui Cardiovascular Center, Shinbo, Fukui, Japan
    Circ J 70:1312-7. 2006
  4. doi request reprint Long QT syndrome and associated gene mutation carriers in Japanese children: results from ECG screening examinations
    Kenshi Hayashi
    Kanazawa University Graduate School of Medical Science, Ishikawa, Japan
    Clin Sci (Lond) 117:415-24. 2009
  5. doi request reprint A KCR1 variant implicated in susceptibility to the long QT syndrome
    Kenshi Hayashi
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    J Mol Cell Cardiol 50:50-7. 2011
  6. doi request reprint Extent of heart rate reduction during hospitalization using beta-blockers, not the achieved heart rate itself at discharge, predicts the clinical outcome in patients with acute heart failure syndromes
    Hiroyuki Takahama
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita 565 8565, Osaka, Japan
    J Cardiol 61:58-64. 2013
  7. ncbi request reprint Differences in diagnostic value of four electrocardiographic voltage criteria for hypertrophic cardiomyopathy in a genotyped population
    Tetsuo Konno
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
    Am J Cardiol 96:1308-12. 2005
  8. ncbi request reprint A successful case of percutaneous transluminal septal myocardial ablation for mitral regurgitation that emerged following mitral valve repair surgery
    Tomohiro Hayashi
    Cardiovascular Division of Medicine, National Cerebral and Cardiovascular Center, Japan
    Intern Med 52:2765-9. 2013
  9. doi request reprint Pathophysiological impact of serum fibroblast growth factor 23 in patients with nonischemic cardiac disease and early chronic kidney disease
    Miki Imazu
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
    Am J Physiol Heart Circ Physiol 307:H1504-11. 2014
  10. doi request reprint Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias
    Takashi Fujita
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    J Cardiol 66:63-8. 2015

Collaborators

Detail Information

Publications21

  1. doi request reprint Late aneurysm formation of Valsalva sinus after aortic valve replacement due to Takayasu's arteritis
    Akira Funada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, 565 8565, Japan
    Heart Vessels 30:558-62. 2015
    ..Close and lifelong follow-up for patients with TA regarding development of aneurysm after surgical treatment is indispensable when fragility of the aortic root had been confirmed. ..
  2. doi request reprint Assessment of QT intervals and prevalence of short QT syndrome in Japan
    Akira Funada
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Clin Cardiol 31:270-4. 2008
    ..Recently, a short QT interval has also been shown to be associated with an increased risk of tachyarrhythmia and sudden death. However, the prevalence of short QT syndrome is not well-known...
  3. ncbi request reprint Three cases of iatrogenic coronary ostial stenosis after aortic valve replacement
    Akira Funada
    Fukui Cardiovascular Center, Shinbo, Fukui, Japan
    Circ J 70:1312-7. 2006
    ..Iatrogenic coronary ostial stenosis (ICOS) is a rare but potentially life-threatening complication of aortic valve replacement (AVR). This complication is usually diagnosed by angiography and treated with aortocoronary bypass surgery...
  4. doi request reprint Long QT syndrome and associated gene mutation carriers in Japanese children: results from ECG screening examinations
    Kenshi Hayashi
    Kanazawa University Graduate School of Medical Science, Ishikawa, Japan
    Clin Sci (Lond) 117:415-24. 2009
    ..038% (one in 2653). Furthermore, large-scale genetic studies will be needed to clarify the real prevalence of LQTS by gene-carrier status, as it may have been underestimated in the present study...
  5. doi request reprint A KCR1 variant implicated in susceptibility to the long QT syndrome
    Kenshi Hayashi
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    J Mol Cell Cardiol 50:50-7. 2011
    ..Our findings suggest that KCR1 genetic variations that diminish the ability of KCR1 to protect KCNH2 from inhibition by commonly used therapeutic agents constitute a risk factor for the aLQTS...
  6. doi request reprint Extent of heart rate reduction during hospitalization using beta-blockers, not the achieved heart rate itself at discharge, predicts the clinical outcome in patients with acute heart failure syndromes
    Hiroyuki Takahama
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita 565 8565, Osaka, Japan
    J Cardiol 61:58-64. 2013
    ..The present study investigated the influence of HRR during hospitalization on the prognosis of AHFS patients...
  7. ncbi request reprint Differences in diagnostic value of four electrocardiographic voltage criteria for hypertrophic cardiomyopathy in a genotyped population
    Tetsuo Konno
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
    Am J Cardiol 96:1308-12. 2005
    ..Therefore, understanding the diagnostic value of classic ECG voltage criteria may be important in detecting carriers, including those without left ventricular hypertrophy...
  8. ncbi request reprint A successful case of percutaneous transluminal septal myocardial ablation for mitral regurgitation that emerged following mitral valve repair surgery
    Tomohiro Hayashi
    Cardiovascular Division of Medicine, National Cerebral and Cardiovascular Center, Japan
    Intern Med 52:2765-9. 2013
    ..After the procedure, the MR resolved, with a reduced LVOT pressure gradient. The patient's symptoms improved. PTSMA was effective for the treatment of MR that emerged after mitral valve repair. ..
  9. doi request reprint Pathophysiological impact of serum fibroblast growth factor 23 in patients with nonischemic cardiac disease and early chronic kidney disease
    Miki Imazu
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
    Am J Physiol Heart Circ Physiol 307:H1504-11. 2014
    ..001). These findings suggest that the progression of HF per se contributes to the elevation of sFGF23 levels even in the early stages of CKD, which leads to further myocardial dysfunction, potentially creating a vicious cycle. ..
  10. doi request reprint Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias
    Takashi Fujita
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    J Cardiol 66:63-8. 2015
    ....
  11. ncbi request reprint Images in cardiovascular medicine. Adult patient with isolated noncompaction of ventricular myocardium
    Tomoya Kaneda
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa 920 8640, Japan
    Circulation 112:e96-7. 2005
  12. doi request reprint Compound heterozygosity deteriorates phenotypes of hypertrophic cardiomyopathy with founder MYBPC3 mutation: evidence from patients and zebrafish models
    Akihiko Hodatsu
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan and
    Am J Physiol Heart Circ Physiol 307:H1594-604. 2014
    ..These results demonstrate that MYBPC3 Val762Asp may be associated with unfavorable HCM phenotypes in some cases when combined with another MYBPC3 mutation. ..
  13. ncbi request reprint Heterogeneity of clinical manifestation of hypertrophic cardiomyopathy caused by deletion of lysine 183 in cardiac troponin I gene
    Akira Funada
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Ishikawa, Japan
    Int Heart J 51:214-7. 2010
    ..The findings suggest that additional genetic or environmental factors influence the phenotypic expressions and clinical courses of HCM caused by genetic mutation of sarcomeric proteins...
  14. ncbi request reprint Impact of renin-angiotensin system polymorphisms on development of systolic dysfunction in hypertrophic cardiomyopathy. Evidence from a study of genotyped patients
    Akira Funada
    Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Circ J 74:2674-80. 2010
    ..The effect of RAS polymorphisms on LV function in genotyped hypertrophic cardiomyopathy (HCM) was examined in the present study...
  15. doi request reprint Prognostic Impact of Functional Mitral Regurgitation in Patients Admitted With Acute Decompensated Heart Failure
    Yuko Wada
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
    Circ J 80:139-47. 2015
    ..It is unclear whether FMR on admission or discharge determines the outcome. This study aimed to elucidate the prognostic significance of FMR on admission or discharge in patients admitted with acute decompensated HF...
  16. ncbi request reprint Gene mutations in adult Japanese patients with dilated cardiomyopathy
    Masami Shimizu
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Japan
    Circ J 69:150-3. 2005
    ..Some patients with dilated cardiomyopathy (DCM) have mutations of the genes that encode sarcomeric or cytoskeletal proteins of cardiomyocytes, but the prevalence of these mutations in Japan remains unclear...
  17. doi request reprint Extensive late gadolinium enhancement on cardiovascular magnetic resonance predicts adverse outcomes and lack of improvement in LV function after steroid therapy in cardiac sarcoidosis
    Takayuki Ise
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
    Heart 100:1165-72. 2014
    ....
  18. ncbi request reprint Differentiation between patients with takotsubo cardiomyopathy and those with anterior acute myocardial infarction
    Masaru Inoue
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
    Circ J 69:89-94. 2005
    ....
  19. ncbi request reprint The incidence of stent-edge spasm after stent implantation in patients with or without vasospastic angina pectoris
    Bunji Kaku
    Department of Internal Medicine, Ishikawa Prefectural Central Hospital, Kanazawa, Japan
    Int Heart J 46:23-33. 2005
    ..7%). Moderate stent-edge spasm was provoked in 5 patients with VSA (19.2%) and 5 patients without VSA (21.7%). The results suggest new onset stent-edge spasm in patients either with or without VSA should not be neglected...
  20. ncbi request reprint Serum blood urea nitrogen and plasma brain natriuretic Peptide and low diastolic blood pressure predict cardiovascular morbidity and mortality following discharge in acute decompensated heart failure patients
    Chun Yen Chen
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5 7 1 Fujishirodai, Suita 565 8565, Japan
    Circ J 76:2372-9. 2012
    ..The purpose of the present study was therefore to investigate predictors of CV death and re-hospitalization for acute decompensated HF (ADHF)...
  21. ncbi request reprint A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings
    Yuhki Horita
    Department of Cardiology, Ishikawa Prefectural Central Hospital, Ishikawa 920 8530, Japan
    Jpn Heart J 45:1049-56. 2004
    ..Estimation of the serum level may be possible from the electrocardiographic findings if the pilsicainide toxicity occurs...