Research Topics
Genomes and GenesSpecies | Akira FunadaSummaryAffiliation: Nagasaki University Country: Japan Publications
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Detail Information
Publications
Three cases of iatrogenic coronary ostial stenosis after aortic valve replacementAkira Funada
Fukui Cardiovascular Center, Shinbo, Fukui, Japan
Circ J 70:1312-7. 2006..Iatrogenic coronary ostial stenosis (ICOS) is a rare but potentially life-threatening complication of aortic valve replacement (AVR). This complication is usually diagnosed by angiography and treated with aortocoronary bypass surgery...
Assessment of QT intervals and prevalence of short QT syndrome in JapanAkira Funada
Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
Clin Cardiol 31:270-4. 2008..Recently, a short QT interval has also been shown to be associated with an increased risk of tachyarrhythmia and sudden death. However, the prevalence of short QT syndrome is not well-known...
A KCR1 variant implicated in susceptibility to the long QT syndromeKenshi Hayashi
Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
J Mol Cell Cardiol 50:50-7. 2011..Our findings suggest that KCR1 genetic variations that diminish the ability of KCR1 to protect KCNH2 from inhibition by commonly used therapeutic agents constitute a risk factor for the aLQTS...
Long QT syndrome and associated gene mutation carriers in Japanese children: results from ECG screening examinationsKenshi Hayashi
Kanazawa University Graduate School of Medical Science, Ishikawa, Japan
Clin Sci (Lond) 117:415-24. 2009..038% (one in 2653). Furthermore, large-scale genetic studies will be needed to clarify the real prevalence of LQTS by gene-carrier status, as it may have been underestimated in the present study...
Differences in diagnostic value of four electrocardiographic voltage criteria for hypertrophic cardiomyopathy in a genotyped populationTetsuo Konno
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
Am J Cardiol 96:1308-12. 2005..Therefore, understanding the diagnostic value of classic ECG voltage criteria may be important in detecting carriers, including those without left ventricular hypertrophy...
Heterogeneity of clinical manifestation of hypertrophic cardiomyopathy caused by deletion of lysine 183 in cardiac troponin I geneAkira Funada
Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Ishikawa, Japan
Int Heart J 51:214-7. 2010..The findings suggest that additional genetic or environmental factors influence the phenotypic expressions and clinical courses of HCM caused by genetic mutation of sarcomeric proteins...
Images in cardiovascular medicine. Adult patient with isolated noncompaction of ventricular myocardiumTomoya Kaneda
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8640, Japan
Circulation 112:e96-7. 2005
Impact of renin-angiotensin system polymorphisms on development of systolic dysfunction in hypertrophic cardiomyopathy. Evidence from a study of genotyped patientsAkira Funada
Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
Circ J 74:2674-80. 2010..The effect of RAS polymorphisms on LV function in genotyped hypertrophic cardiomyopathy (HCM) was examined in the present study...
Gene mutations in adult Japanese patients with dilated cardiomyopathyMasami Shimizu
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Japan
Circ J 69:150-3. 2005..Some patients with dilated cardiomyopathy (DCM) have mutations of the genes that encode sarcomeric or cytoskeletal proteins of cardiomyocytes, but the prevalence of these mutations in Japan remains unclear...
Differentiation between patients with takotsubo cardiomyopathy and those with anterior acute myocardial infarctionMasaru Inoue
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
Circ J 69:89-94. 2005..The ECG findings in TC did not differ from those in group C. CONCLUSION: Electrocardiographic findings may differentiate TC from AMI with a proximal lesion of left anterior descending coronary artery, but not those with distal lesions...
The incidence of stent-edge spasm after stent implantation in patients with or without vasospastic angina pectorisBunji Kaku
Department of Internal Medicine, Ishikawa Prefectural Central Hospital, Kanazawa, Japan
Int Heart J 46:23-33. 2005..7%). Moderate stent-edge spasm was provoked in 5 patients with VSA (19.2%) and 5 patients without VSA (21.7%). The results suggest new onset stent-edge spasm in patients either with or without VSA should not be neglected...
A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findingsYuhki Horita
Department of Cardiology, Ishikawa Prefectural Central Hospital, Ishikawa 920-8530, Japan
Jpn Heart J 45:1049-56. 2004..Estimation of the serum level may be possible from the electrocardiographic findings if the pilsicainide toxicity occurs...
