Research Topics
| Noritoshi TakahashiSummaryAffiliation: Morinaga Milk Industry Co Country: Japan Publications
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Detail Information
Publications
An immunostimulatory DNA sequence from a probiotic strain of Bifidobacterium longum inhibits IgE production in vitroNoritoshi Takahashi
Food Research and Development Laboratory, Morinaga Milk Industry Co, Ltd, Zama, Kanagawa, Japan
FEMS Immunol Med Microbiol 46:461-9. 2006..The results suggest the potential of ODNs BL07 and BL07S in preventing IgE-related immune responses and the possible involvement of ODN BL07 in the antiallergic efficacy of B. longum BB536...
Immunostimulatory oligodeoxynucleotide from Bifidobacterium longum suppresses Th2 immune responses in a murine modelN Takahashi
Food Research and Development Laboratory, Morinaga Milk Industry Co Ltd, Zama, Japan
Clin Exp Immunol 145:130-8. 2006..The present results demonstrate that ODN BL07S from genomic DNA of B. longum BB536 prevents antigen-induced Th2 immune responses in vivo, suggesting that ISS-ODNs from probiotics might be useful in preventing allergic disease...
Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine modelNoritoshi Takahashi
Food Research and Development Laboratory, Morinaga Milk Industry Co, Ltd, Zama, Japan
Biosci Biotechnol Biochem 70:2013-7. 2006..ODN BL07S increased Th1 cytokine and decreased Th2 cytokine production in splenocytes. These results suggest that immunostimulatory ODNs are potentially associated with the antiallergic effects of probiotics...
In vitro Th1 cytokine-independent Th2 suppressive effects of bifidobacteriaNoriyuki Iwabuchi
Food Science and Technology Institute, Morinaga Milk Industry Co, Ltd, Zama, Kanagawa, Japan
Microbiol Immunol 51:649-60. 2007..These results suggested that BB536 suppressed Th2 immune responses, partially independent of Th1-inducing cytokines and independent of regulatory cytokines, mediated by antigen-presenting cells such as dendritic cells...
Influence of Bifidobacterium longum BB536 intake on faecal microbiota in individuals with Japanese cedar pollinosis during the pollen seasonToshitaka Odamaki
Food Research and Development Laboratory Morinaga Milk Industry Co Ltd, Zama, Kanagawa 228 8583, Japan
J Med Microbiol 56:1301-8. 2007..05). These results suggest that faecal microbiota in JCPsis subjects, but not healthy subjects, fluctuate at the end of the pollen season and that BB536 intake plays a role in maintaining normal microbiota...
Changes in plasma TARC levels during Japanese cedar pollen season and relationships with symptom developmentJin Zhong Xiao
Food Research and Development Laboratory, Morinaga Milk Industry, Zama, Japan
Int Arch Allergy Immunol 144:123-7. 2007..The present study aims to evaluate the relationship between TARC levels and disease symptoms during the pollen season...
Selection of acid tolerant bifidobacteria and evidence for a low-pH-inducible acid tolerance response in Bifidobacterium longumNoritoshi Takahashi
Food Research and Development Laboratory, Morinaga Milk Industry Co, Ltd, Zama-City, Japan
J Dairy Res 71:340-5. 2004..These results suggested that a cytoplasmic pH homeostasis system may function in the acid tolerance response in this strain...
Suppressive effects of Bifidobacterium longum on the production of Th2-attracting chemokines induced with T cell-antigen-presenting cell interactionsNoriyuki Iwabuchi
Department of Applied Biological Chemistry, University of Tokyo, Tokyo, Japan
FEMS Immunol Med Microbiol 55:324-34. 2009..These results indicate that BB536 suppresses the production of Th2-attracting chemokines induced by the T cell-APC interaction, suggesting a novel mechanism for alleviating symptoms of allergic disorders by probiotics...
Suppressive effects of dietary fiber in yogurt on the postprandial serum lipid levels in healthy adult male volunteersShizuki Kondo
Food Research and Development Laboratory, Morinaga Milk Industry Co, Ltd, Zama, Japan
Biosci Biotechnol Biochem 68:1135-8. 2004..The results suggest the potential of PHGG to reduce the risk of hyperlipemia...
