Kenji Mori

Summary

Country: Japan

Publications

  1. ncbi request reprint Synthesis of the enantiomers of 21-methyl-7-hentriacontanone and a stereoisomeric mixture of 5-acetoxy-19-methylnonacosane, candidates for the female sex pheromone of the screwworm fly Cochliomyia hominivorax
    Kenji Mori
    Insect Pheromone and Traps Division, Fuji Flavor Co, Ltd, Midorigaoka, Hamura City, Tokyo, Japan
    Biosci Biotechnol Biochem 67:2224-31. 2003
  2. ncbi request reprint Synthesis of the four stereoisomers of 7-acetoxy-15-methylnonacosane, a component of the female sex pheromone of the screwworm fly, Cochliomyia hominivorax
    Kenji Mori
    Insect Pheromone and Traps Division, Fuji Flavor Co, Ltd, Midorigaoka 3 5 8, Hamura shi, Tokyo 205 8503, Japan
    Biosci Biotechnol Biochem 68:1768-78. 2004
  3. ncbi request reprint Synthetic examination of incorrectly proposed structures of biomolecules
    Kenji Mori
    Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, RIKEN Research Center for Allergy and Immunology, c o Seikagaku Corporation, 3 1253 Tateno, Higashiyamato shi, Tokyo 207 0021, Japan
    Chem Rec 5:1-16. 2005
  4. doi request reprint Synthesis and biological activity of hydroxylated analogues of KRN7000 (α-galactosylceramide)
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Wako Shi, Saitama, Japan
    Carbohydr Res 370:46-66. 2013
  5. doi request reprint RCAI-61 and related 6'-modified analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce interferon-γ in vivo
    Takuya Tashiro
    Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    Bioorg Med Chem 21:3066-79. 2013
  6. doi request reprint RCAI-84, 91, and 105-108, ureido and thioureido analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines
    Takuya Tashiro
    Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan
    Bioorg Med Chem 20:4540-8. 2012
  7. ncbi request reprint A case of Kabuki syndrome presenting West syndrome
    Hiromichi Ito
    Department of Pediatrics, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Brain Dev 29:380-2. 2007
  8. doi request reprint Serial brain imaging analysis of stroke-like episodes in MELAS
    Hiromichi Ito
    Department of Pediatrics, School of Medicine, University of Tokushima, 3 18 15, Kuramoto Cho, Tokushima 770 8503, Japan
    Brain Dev 30:483-8. 2008
  9. ncbi request reprint Somatosensory evoked potentials in attention deficit/hyperactivity disorder and tic disorder
    Masahito Miyazaki
    Department of Pediatrics, The Institute of Health Bioscience, The University of Tokushima Graduate School, Tokushima, Japan
    Clin Neurophysiol 118:1286-90. 2007
  10. ncbi request reprint Long-term follow-up of a patient with subacute sclerosing panencephalitis successfully treated with intrathecal interferon alpha
    Masahito Miyazaki
    Department of Pediatrics, School of Medicine, University of Tokushima, Tokushima, Japan
    Brain Dev 27:301-3. 2005

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Synthesis of the enantiomers of 21-methyl-7-hentriacontanone and a stereoisomeric mixture of 5-acetoxy-19-methylnonacosane, candidates for the female sex pheromone of the screwworm fly Cochliomyia hominivorax
    Kenji Mori
    Insect Pheromone and Traps Division, Fuji Flavor Co, Ltd, Midorigaoka, Hamura City, Tokyo, Japan
    Biosci Biotechnol Biochem 67:2224-31. 2003
    ..hominivorax. Synthetic 2 exhibited no pheromone activity against male C. hominivorax...
  2. ncbi request reprint Synthesis of the four stereoisomers of 7-acetoxy-15-methylnonacosane, a component of the female sex pheromone of the screwworm fly, Cochliomyia hominivorax
    Kenji Mori
    Insect Pheromone and Traps Division, Fuji Flavor Co, Ltd, Midorigaoka 3 5 8, Hamura shi, Tokyo 205 8503, Japan
    Biosci Biotechnol Biochem 68:1768-78. 2004
    ..Three of the stereoisomers of 1 showed equivalent good pheromone activity, while the activity of (7R,15R)-1 was weak...
  3. ncbi request reprint Synthetic examination of incorrectly proposed structures of biomolecules
    Kenji Mori
    Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, RIKEN Research Center for Allergy and Immunology, c o Seikagaku Corporation, 3 1253 Tateno, Higashiyamato shi, Tokyo 207 0021, Japan
    Chem Rec 5:1-16. 2005
    ....
  4. doi request reprint Synthesis and biological activity of hydroxylated analogues of KRN7000 (α-galactosylceramide)
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Wako Shi, Saitama, Japan
    Carbohydr Res 370:46-66. 2013
    ..It was recognized that two compounds RCAI-147/-160 showed good suppression of EAE symptoms...
  5. doi request reprint RCAI-61 and related 6'-modified analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce interferon-γ in vivo
    Takuya Tashiro
    Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    Bioorg Med Chem 21:3066-79. 2013
    ....
  6. doi request reprint RCAI-84, 91, and 105-108, ureido and thioureido analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines
    Takuya Tashiro
    Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan
    Bioorg Med Chem 20:4540-8. 2012
    ..The hexadecyl ureido analog [RCAI-84 (2)] was comparable to KRN7000 in its bioactivity. The octylureido [RCAI-107 (3)], 5-phenylpentylureido [RCAI-108 (5)], and thioureido [RCAI-91 (6)] analogs were almost inactive...
  7. ncbi request reprint A case of Kabuki syndrome presenting West syndrome
    Hiromichi Ito
    Department of Pediatrics, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan
    Brain Dev 29:380-2. 2007
    ..To the best of our knowledge, Kabuki syndrome presenting West syndrome has been reported in only one previous case. We must pay attention to the occurrence of West syndrome in Kabuki syndrome...
  8. doi request reprint Serial brain imaging analysis of stroke-like episodes in MELAS
    Hiromichi Ito
    Department of Pediatrics, School of Medicine, University of Tokushima, 3 18 15, Kuramoto Cho, Tokushima 770 8503, Japan
    Brain Dev 30:483-8. 2008
    ..These results suggest that the stroke-like episodes is related to vasogenic edema, hyperperfusion, and neuronal damage. Acute oxidative phosphorylation defect may have a crucial role in the pathophysiology of stroke-like episodes...
  9. ncbi request reprint Somatosensory evoked potentials in attention deficit/hyperactivity disorder and tic disorder
    Masahito Miyazaki
    Department of Pediatrics, The Institute of Health Bioscience, The University of Tokushima Graduate School, Tokushima, Japan
    Clin Neurophysiol 118:1286-90. 2007
    ..Therefore, we hypothesized that they might have a common pathophysiology involving the somatosensory system, especially hyper-excitabilities of primary somatosensory area...
  10. ncbi request reprint Long-term follow-up of a patient with subacute sclerosing panencephalitis successfully treated with intrathecal interferon alpha
    Masahito Miyazaki
    Department of Pediatrics, School of Medicine, University of Tokushima, Tokushima, Japan
    Brain Dev 27:301-3. 2005
    ..Thus, IFN-alpha-induced remission appears most likely to be temporary, even when an SSPE patient shows an excellent initial response. To improve long-term outcome for SSPE patients, more effective therapy is needed...
  11. ncbi request reprint New synthesis of (11Z,13Z)-11,13-hexadecadienal, the female sex pheromone of the navel orangeworm
    Kenji Mori
    Photosensitive Materials Research Center, Toyo Gosei Co, Ltd, Inba gun, Chiba, Japan
    Biosci Biotechnol Biochem 73:2727-30. 2009
    ..The terminal formyl group was installed in the earlier stage of the synthesis rather than in the final step. This procedure enabled the multi-gram-scale preparation of this economically important pheromone...
  12. ncbi request reprint New syntheses of 1,7-dimethylnonyl propanoate, the western corn rootworm pheromone, in four different ways via cross metathesis, alkylation and coupling reactions
    Kenji Mori
    Photosensitive Materials Research Center, Toyo Gosei Co, Ltd, Inba gun, Chiba, Japan
    Biosci Biotechnol Biochem 74:595-600. 2010
    ....
  13. ncbi request reprint Favorable response of ADHD with giant SEP to extended-release valproate
    Masahito Miyazaki
    Department of Pediatrics, Institute of Health Biosciences, The University of Tokushima Graduate, Tokushima, Japan
    Brain Dev 28:470-2. 2006
    ..Improvement particularly involved hyperactivity and impulsivity. When methylphenidate previously was administered to two patients, symptoms worsened. EVA therefore may be preferable for ADHD with giant SEP...
  14. ncbi request reprint Short-latency somatosensory evoked potentials in infantile autism: evidence of hyperactivity in the right primary somatosensory area
    Masahito Miyazaki
    Department of Paediatrics, Miyoshi Medical Clinic, Higashikagawa, Japan
    Dev Med Child Neurol 49:13-7. 2007
    ..This is believed to contribute to the pathophysiology of infantile autism, especially the idiopathic form...
  15. ncbi request reprint Synthesis of sphingolipids with an ω-esterified long acyl chain, ceramide components of the human epidermis
    Takuya Tashiro
    Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Biosci Biotechnol Biochem 76:1715-20. 2012
    ..We synthesized these ceramides by employing olefin cross metathesis as the key reaction for constructing their ω-hydroxytriacontanoyl part (13)...
  16. doi request reprint Synthesis and biological activity of ester and ether analogues of alpha-galactosylceramide (KRN7000)
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan
    Carbohydr Res 345:1663-84. 2010
    ..Ester analogues 30a, 31a, and 61 showed activity for IFNgamma and IL-4 production of iNKT cells, while ether (31b) and 4-methoxy ester (76) analogues of alpha-galactosylceramide were not active for iNKT cells...
  17. ncbi request reprint Syntheses of 2-Isopropyl-4,5-dihydrothiazole and 6-Hydroxy-6-methyl-3-heptanone, pheromone components of the male mouse, Mus musculus
    Takuya Tashiro
    Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, RIKEN Research Center for Allergy and Immunology, Saitama, Japan
    Biosci Biotechnol Biochem 72:2398-402. 2008
    ..Syntheses of 2-isopropyl-4,5-dihydrothiazole and 6-hydroxy-6-methyl-3-heptanone, pheromone components of the male mouse, Mus musculus, were achieved to provide sufficient amounts of samples for biological studies...
  18. pmc Pharmacokinetics and effects of ribavirin following intraventricular administration for treatment of subacute sclerosing panencephalitis
    Mitsuaki Hosoya
    Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan
    Antimicrob Agents Chemother 48:4631-5. 2004
    ..Intraventricular ribavirin therapy should be pursued further for its potential use for patients with SSPE and might be applied in the treatment of patients with encephalitis caused by other RNA viruses...
  19. ncbi request reprint Syntheses of racemic and diastereomeric mixtures of 3,7,11,15-tetramethylhentriacontane and 4,8,12,16-tetramethyldotriacontane, the cuticular tetramethylalkanes of the tsetse fly, Glossina brevipalpis
    Chié Shibata
    Department of Chemistry, Faculty of Science, Science University of Tokyo, Japan
    Biosci Biotechnol Biochem 66:582-7. 2002
    ..These were synthesized as racemic and diastereomeric mixtures starting from racemic citronellol and employing phenyl-sulfone-mediated chain-elongation as the key reaction...
  20. ncbi request reprint Synthesis of (4R,6S,7R)-7-hydroxy-4,6-dimethyl-3-nonanone and (3R,5S,6R)- 6-hydroxy-3,5-dimethyl-2-octanone, the pheromone components of the bostrychid beetle, Dinoderus bifoveolatus
    Yui Masuda
    Department of Chemistry, Graduate School of Science, Science University of Tokyo, Kagurazaka 1 3, Shinjuku ku, Tokyo 162 8601, Japan
    Biosci Biotechnol Biochem 67:1744-50. 2003
    ....
  21. ncbi request reprint Determination of the absolute configuration of (+)-xestoaminol C [(2S, 3R)-2-amino-3-tetradecanol], a metabolite of Fiji sponge, Xestospongia sp., by the synthesis of its N,O-diacetyl derivative
    Miwako Ichihashi
    Department of Chemistry, Graduate School of Science, Science University of Tokyo, Kagurazaka 1 3, Shinjuku ku, Tokyo 162 8601, Japan
    Biosci Biotechnol Biochem 67:329-33. 2003
    ..The N,O-diacetyl derivative of (+)-xestoaminol C (2-amino-3-tetradecanol, 1), an inhibitor of reverse transcriptase isolated from Xestospongia sp., was synthesized from (S)-alanine, and its absolute configuration was determined as 2S, 3R...
  22. ncbi request reprint Synthesis of the four stereoisomers of 3,12-dimethylheptacosane, (Z)-9-pentacosene and (Z)-9-heptacosene, the cuticular hydrocarbons of the ant, Diacamma sp
    Yui Masuda
    Department of Chemistry, Faculty of Science, Science University of Tokyo, Japan
    Biosci Biotechnol Biochem 66:1032-8. 2002
    ..Z)-9-Pentacosene and (Z)-9-heptacosene were also synthesized. These hydrocarbons are the characteristic components of the cuticular hydrocarbons of the queen of the ant, Diacamma sp....
  23. ncbi request reprint Successful management of intractable epilepsy with lidocaine tapes and continuous subcutaneous lidocaine infusion
    Kenji Mori
    Department of Pediatrics, School of Medicine, Tokushima University, Kuramoto Cho, Japan
    Epilepsia 45:1287-90. 2004
    ..We report the successful management of a 10-year-old girl with intractable frontal lobe epilepsy by using lidocaine tapes and continuous subcutaneous lidocaine infusion...
  24. ncbi request reprint A case of idiopathic portal hypertension associated with rheumatoid arthritis
    Tomomi Sasajima
    Department of Internal Medicine II, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, 960 1295, Japan
    Mod Rheumatol 16:92-6. 2006
    ..In this case, the autoimmune mechanism as well as hypersplenism was suspected of being involved in the mechanism of thrombocytopenia...
  25. ncbi request reprint Patients with West syndrome whose ictal SPECT showed focal cortical hyperperfusion
    Kenji Mori
    Department of Pediatrics, School of Medicine, Tokushima University, Kuramoto Cho, Tokushima, Japan
    Brain Dev 29:202-9. 2007
    ....
  26. ncbi request reprint Pheromonal activity of compounds identified from male Phyllotreta cruciferae: field tests of racemic mixtures, pure enantiomers, and combinations with allyl isothiocyanate
    Miklos Toth
    Plant Protection Institute, Hungarian Academy of Sciences, Pf 102, 1525 Budapest, Hungary
    J Chem Ecol 31:2705-20. 2005
    ..During field trials, several congeneric species, including P. vittula, P. nemorum, P. nodicornis, and P. ochripes, also were caught, suggesting that the same compound(s) may be relatively widespread as pheromone components in this genus...
  27. ncbi request reprint Synthetic study towards azadirachtin: an efficient and stereoselective construction of the AB rings with full functionality
    Hidenori Watanabe
    Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Angew Chem Int Ed Engl 46:1512-6. 2007
  28. ncbi request reprint Evidence that (+)-endo-brevicomin is a male-produced component of the Southern pine beetle aggregation pheromone
    Brian T Sullivan
    USDA Forest Service, Southern Research Station, 2500 Shreveport Hwy, Pineville, LA 71360, USA
    J Chem Ecol 33:1510-27. 2007
    ..Additionally, baits fortified with (+)-endo-brevicomin may enhance pest management strategies that exploit attractants for D. frontalis...
  29. ncbi request reprint Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos
    Yoshiyuki Mizushina
    Department of Nutritional Science, Kobe Gakuin University, Nishi ku, Kobe, Hyogo 651 2180
    J Biochem 133:541-52. 2003
    ..We also discussed the in vivo role of HA-A...
  30. ncbi request reprint [Neuroradiological studies in Rett syndrome]
    Yoshimi Tsuda
    Handicapped Children, Naruto University of Education, Naruto, Tokushima
    No To Hattatsu 40:313-8. 2008
    ..We speculated that this decrease in NAA reflected neuronal loss, immaturity or hypofunction in these regions. The results of our study were in agreement with the previous studies on Rett syndrome by neuropathological methods...
  31. ncbi request reprint [Congenital absence of the portal vein in an adult woman with liver tumor]
    Satoshi Maekawa
    Department of Gastroenterology, Fukushima Rosai Hospital
    Nihon Shokakibyo Gakkai Zasshi 104:1504-11. 2007
    ..Most cases on diagnosed in childhood, although this case was found in on adult. We reviewed the literature on reported CAPV cases...
  32. ncbi request reprint [A preliminary fMRI study of moral judgment task in high functioning autistic children]
    Hirotoshi Hiraishi
    Primate Research Institute, Kyoto University, Inuyama, Aichi
    No To Hattatsu 39:360-5. 2007
    ..Recently Greene et al. reported that the prefrontal cortex was active during moral judgment in an fMRI study of normally developed people. Their result reinforces our results...
  33. ncbi request reprint Significance of chirality in pheromone science
    Kenji Mori
    Photosensitive Materials Research Center, Toyo Gosei Co, Ltd, Wakahagi 4 2 1, Inba mura, Inba gun, Chiba 270 609, Japan
    Bioorg Med Chem 15:7505-23. 2007
    ..Problems encountered in studying chirality of pheromones were examined and analyzed to think about possible future directions in pheromone science...
  34. ncbi request reprint Growth of head circumference in autistic infants during the first year of life
    Aya Fukumoto
    Division of Human Development and Health Sciences, Subdivision of Human Development, Department of Pediatrics, Institute of Health Biosciences, University of Tokushima Graduate School, 3 18 15, Kuramoto Cho, Tokushima 770 8503, Japan
    J Autism Dev Disord 38:411-8. 2008
    ..The discrepancy reached a peak at 6 months, while the difference became smaller at 12 months. Body length (BL) and body weight (BW) began to increase at 3 months, although at a rate smaller than the head circumference increase...
  35. ncbi request reprint 3-boryl-2,2'-bithiophene as a versatile core skeleton for full-color highly emissive organic solids
    Atsushi Wakamiya
    Department of Chemistry, Graduate School of Science, Nagoya University, Japan
    Angew Chem Int Ed Engl 46:4273-6. 2007
  36. ncbi request reprint Structure and function of the antennal sensilla of the palm weevil Rhynchophorus palmarum (Coleoptera, Curculionidae)
    Imen Saïd
    Unité de Phytopharmacie and Médiateurs Chimiques, INRA, Route de Saint Cyr, 78026 Versailles Cedex, France
    J Insect Physiol 49:857-72. 2003
    ..This suggests an interaction at the sensory neuron level between pheromone and plant odors, triggering synergic behavioral responses...
  37. ncbi request reprint A case of acute encephalitis with refractory, repetitive partial seizures, presenting autoantibody to glutamate receptor Gluepsilon2
    Hiromichi Ito
    Department of Pediatrics, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15, Kuramoto Cho, Tokushima 770 8503, Japan
    Brain Dev 27:531-4. 2005
    ..In this case, a combination of mild hypothermia therapy, steroid pulse therapy, and massive gamma-globulin therapy was effective...
  38. ncbi request reprint Administration of secretin for autism alters dopamine metabolism in the central nervous system
    Yoshihiro Toda
    Department of Pediatrics, School of Medicine, University of Tokushima, 3 18 15, Kuramoto Cho, Tokushima shi, Tokushima 770 8503, Japan
    Brain Dev 28:99-103. 2006
    ..In contrast, no patient without the elevation of the BH(4) level showed improvement in the score. These findings suggest that secretin activated metabolic turnover of dopamine in the central nervous system via BH(4), improving symptoms...
  39. ncbi request reprint Synthesis and absolute configuration of (-)-3-butyl-7-hydroxyphthalide, a cytotoxic metabolite of Penicillium vulpinum
    Tomoya Ohzeki
    Department of Chemistry, Graduate School of Science, Science University of Tokyo, Kagurazaka, Tokyo, Japan
    Biosci Biotechnol Biochem 67:2240-4. 2003
    ..Both the enantiomers as well as the racemate of 3-butyl-7-hydroxyphthalide (1) were synthesized, and the absolute configuration of the naturally occurring (-)-1 (a weakly cytotoxic metabolite of Penicillium vulpinum) was identified as S...
  40. ncbi request reprint Trial of intraventricular ribavirin therapy for subacute sclerosing panencephalitis in Japan
    Akemi Tomoda
    Department of Child Development, Kumamoto University School of Medicine, 1 1 1 Honjo, Kumamoto 860 0811, Japan
    Brain Dev 25:514-7. 2003
    ..Although effectiveness varied among cases, they were all treated safely with intraventricular ribavirin. This study suggests that treatment is safe and well-tolerated...
  41. ncbi request reprint Behavioral and electrophysiological responses of the brownbanded cockroach, Supella longipalpa, to stereoisomers of its sex pheromone, supellapyrone
    César Gemeno
    Department of Entomology and W M, Keck Center for Behavioral Biology, North Carolina State University, Gardner Hall Box 7613, Raleigh, North Carolina 27695 7613, USA
    J Chem Ecol 29:1797-811. 2003
    ..Therefore, peak height and width are independent parameters of the EAG, probably representing different intrasensillar events, and likely resulting in the expression of different behavioral responses...
  42. ncbi request reprint Synthesis of the four components of the female sex pheromone of the painted apple moth, Teia anartoides
    Shin Etsu Muto
    Insect Pheromone and Traps Division, Fuji Flavor Co, Ltd, Hamura City, Tokyo, Japan
    Biosci Biotechnol Biochem 67:1559-67. 2003
    ..2-Dodecanone was converted to 1 and 2, and both the enantiomers of 3 and 4 were synthesized from the enantiomers of 4-tert-butyldimethylsilyloxy-cis-2,3-epoxy-1-butanol...
  43. ncbi request reprint Magnetic resonance imaging and spectroscopy in a patient with treated methylmalonic acidemia
    Mayumi Takeuchi
    Department of Radiology, University of Tokushima, 3 18 15 Kuramoto cho, Tokushima, Japan
    J Comput Assist Tomogr 27:547-51. 2003
    ..MRI and proton MRS may serve as a suitable, noninvasive modality for monitoring treated MMA...
  44. ncbi request reprint Effect of electric field on the enhanced skin permeation of drugs by electroporation
    Kenji Mori
    Tsukuba Research Laboratories, Hisamitsu Pharmaceutical Co Ltd, 1 25 11 Kannondai, Tsukuba, Ibaraki 305 0856, Japan
    J Control Release 90:171-9. 2003
    ....
  45. ncbi request reprint Magnetic resonance imaging and proton MR spectroscopy of the brain in a patient with carbohydrate-deficient glycoprotein syndrome type I
    Mayumi Takeuchi
    Department of Radiology, School of Medicine, University of Tokushima, Tokushima, Japan
    J Magn Reson Imaging 17:722-5. 2003
    ..In the parietal lobe, there was an increased concentration of Glx, possibly reflecting dysfunction caused by liver injury...
  46. ncbi request reprint Determination of the stereochemistry of (-)-koninginin A by an X-ray analysis of its synthetic sample
    Kenji Mori
    Insect Pheromone and Traps Division, Fuji Flavor Co Ltd, Hamura City, Tokyo, Japan
    Biosci Biotechnol Biochem 66:1779-81. 2002
    ....
  47. ncbi request reprint Synthesis of (2S,2'R,3S,4R)-2-(2'-hydroxy-21'-methyidocosanoylamino)-1,3,4-pentadecanetriol, the ceramide sex pheromone of the female hair crab, Erimacrus isenbeckii
    Yui Masuda
    Department of Chemistry, Graduate School of Science, Science University of Tokyo, Japan
    Biosci Biotechnol Biochem 66:1531-7. 2002
    ..The ceramide sex pheromone [(2S,2'R,3S,4R)-2-(2'-hydroxy-21-methyldocosanoylamino)-1,3,4-pentadecanetriol (1)] of the female hair crab (Erimacrus isenbeckii) was synthesized by starting from (S)-serine and 12-bromo-1-dodecanol...
  48. ncbi request reprint Syntheses of four methyl-branched secondary acetates and a methyl-branched ketone as possible candidates for the female pheromone of the screwworm fly, Cochliomyia hominivorax
    Ayako Furukawa
    Department of Chemistry, Faculty of Science, Science University of Tokyo, Japan
    Biosci Biotechnol Biochem 66:1164-9. 2002
    ..These are new compounds isolated from an HPLC fraction of the female hexane extract which elicited mating responses in the male screwworm fly, Cochliomyia hominivorax...
  49. ncbi request reprint [An open trial of risperidone in autistic children]
    Mio Nishimura
    Department of Pediatrics, Tokushima University School of Medicine, Tokushima
    No To Hattatsu 35:473-7. 2003
    ..Risperidone might be effective for serious behavioral disturbances in young autistic children...
  50. ncbi request reprint Synthetic racemate and enantiomers of cytosporone E, a metabolite of an endophytic fungus, show indistinguishably weak antimicrobial activity
    Tomoya Ohzeki
    Department of Chemistry, Graduate School of Science, Science University of Tokyo, Japan
    Biosci Biotechnol Biochem 67:2584-90. 2003
    ..The racemate and enantiomers of cytosporone E showed only weak antimicrobial activity with no difference among them...
  51. ncbi request reprint Single-strand conformation polymorphism analysis of the FMR1 gene in autistic and mentally retarded children in Japan
    Kumi Shinahara
    Department of Pediatrics, The University of Tokushima School of Medicine, Tokushima, Japan
    J Med Invest 51:52-8. 2004
    ..Although uncommon, point mutations in the FMR1 gene may be a cause of autism and mental retardation in Japanese patients...
  52. ncbi request reprint New synthesis of the (3Z,6Z,9S,10R)-isomers of 9,10-epoxy-3,6-henicosadiene and 9,10-epoxy-1,3,6-henicosatriene, pheromone components of the female fall webworm moth, Hyphantria cunea
    Akira Nakanishi
    Department of Applied Biological Chemistry, The University of Tokyo, Tokyo
    Biosci Biotechnol Biochem 69:1007-13. 2005
    ..Epoxide 8 was prepared by employing lipase-catalyzed asymmetric acetylation of (+/-)-8 as the key optical resolution step...
  53. ncbi request reprint [Autistic disorders]
    Toshiaki Hashimoto
    Department of Education for Disabilities, Naruto University of Education, Naruto, Tokushima
    No To Hattatsu 37:124-9. 2005
    ..However, early interventions are controversial. We discuss early diagnosis and interventions in children with autism in this paper...
  54. ncbi request reprint Findings of brain 99mTc-ECD SPECT in high-functioning autism--3-dimensional stereotactic ROI template analysis of brain SPECT
    Hiromichi Ito
    Department of Pediatrics, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    J Med Invest 52:49-56. 2005
    ....
  55. ncbi request reprint [High functioning pervasive developmental disorder: coexistence with other clinical disorders]
    Mio Nishimura
    Department of Pediatrics, Tokushima University School of Medicine, Tokushima
    No To Hattatsu 37:26-30. 2005
    ..Since clinical symptoms of HFPDD so diverse, it is possible that some children with HFPDD may be overlooked and diagnosed as having its coexisting disorders...
  56. ncbi request reprint [An autopsy case of hepatocellular carcinoma with pleural metastasis]
    Yukari Tanioka
    Department of Gastroenterology, Shimonoseki City Hospital
    Nihon Shokakibyo Gakkai Zasshi 101:1320-4. 2004
  57. ncbi request reprint Behavioral activity of stereoisomers and a new component of the contact sex pheromone of female German cockroach, Blattella germanica
    Dorit Eliyahu
    Department of Entomology and W M Keck Center for Behavioral Biology, North Carolina State University, Raleigh, North Carolina 27695 7613, USA
    J Chem Ecol 30:1839-48. 2004
    ..We now confirm that synthetic (3S,11S)-3,11-dimethylheptacosan-2-one elicits behavioral responses, but less so than its C29 homolog...
  58. ncbi request reprint [Efficacy of secretin for the treatment of autism]
    Yoshihiro Toda
    Department of Pediatrics, School of Medicine, University of Tokushima, Tokushima
    No To Hattatsu 36:289-95. 2004
    ..These findings suggest that secretin promotes the metabolism of serotonin and dopamine in the central nervous system, which may contribute to improvement in clinical symptoms of autism...
  59. ncbi request reprint Self-limited colitis during the course of rubella and cytomegalovirus infection in an immunocompetent adult
    Kota Sugisaki
    Division of Gastroenterology, Fukushima Rosai Hospital, 3 Numajiri, Tsuzurimachi, Uchigo, Iwaki 973 8403
    Intern Med 43:404-9. 2004
    ..The symptoms, laboratory data and colonoscopic findings improved without any medical treatment. This case indicates that UC-like self-limited colitis can occur in an immunocompetent individual during the course of CMV infection...
  60. ncbi request reprint Revision of the structure of the major aggregation pheromone of the broad-horned flour beetle (Gnatocerus cornutus) to (1S,4R,5R)-alpha-acoradiene by its synthesis
    Takuya Tashiro
    Department of Chemistry, Science University of Tokyo, Japan
    Biosci Biotechnol Biochem 68:663-70. 2004
    ..1S,4R,5R)-(+)-alpha-acoradiene [1,8-dimethyl-4-(1-methylethenyl)spiro[4.5]dec-7-ene] (1) is shown by its synthesis to be the major component of the male-produced aggregation pheromone of the broad-horned flour beetle (Gnatocerus cornutus)...
  61. ncbi request reprint Difference of signal change by a language task on autistic patients using functional MRI
    Mayumi Takeuchi
    Department of Radiology, School of Health Sciences, The University of Tokushima School of Medicine, Tokushima, Japan
    J Med Invest 51:59-62. 2004
    ..Cerebral function with a language task was evaluated by functional magnetic resonance imaging (MRI), and the differences of activated pattern and signal changes were compared between autistic patients and normal controls...
  62. ncbi request reprint Synthesis of (1R,2S)-1-(3'-chloro-4' -methoxyphenyl)-1,2-propanediol (trametol) and (1R,2S)-1-(3',5'-dichloro-4'-methoxyphenyl)-1,2-propanediol, chlorinated fungal metabolites in the natural environment
    Takeshi Kousaka
    Department of Mathematics and Science Education, Graduate School of Science, Science University of Tokyo, Japan
    Biosci Biotechnol Biochem 66:697-701. 2002
    ..Similarly, the (1R,2S)-isomer of 1-(3',5'-dichloro-4'-methoxyphenyl)-1,2-propanediol (4), another metabolite of Bjerkandera sp. BOS55, was synthesized by asymmetric dihydroxylation...