Affiliation: Chugai Pharmaceutical Co., Ltd.
Location: Kamakura, Japan
- ORI-GENE: gene classification based on the evolutionary treeH Mizuno
Institute of Biological Sciences, University of Tsukuba, 1 1 1 Ten nodai, Tsukuba, Ibaraki 305 8572, Japan
Bioinformatics 17:167-73. 2001..Therefore, new methods and tools for extracting more biological information from homology searches would be advantageous...
- Mutant p53 disrupts mammary tissue architecture via the mevalonate pathwayWilliam A Freed-Pastor
Department of Biological Sciences, Columbia University, New York, NY 10027, USA
Cell 148:244-58. 2012..Finally, p53 mutation correlates with highly expressed sterol biosynthesis genes in human breast tumors. These findings implicate the mevalonate pathway as a therapeutic target for tumors bearing mutations in p53...