Y Ishimi

Summary

Affiliation: Mitsubishi Kagaku Institute of Life Sciences
Country: Japan

Publications

  1. request reprint
    Ishimi Y. A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex. J Biol Chem. 1997;272:24508-13 pubmed
    ..These results suggest that this helicase may be involved in the initiation of DNA replication as a DNA unwinding enzyme. ..
  2. request reprint
    Ishimi Y, Komamura Kohno Y. Phosphorylation of Mcm4 at specific sites by cyclin-dependent kinase leads to loss of Mcm4,6,7 helicase activity. J Biol Chem. 2001;276:34428-33 pubmed
    ..These results suggest that phosphorylation of Mcm4 at specific sites leads to loss of Mcm4,6,7 DNA helicase activity. ..
  3. request reprint
    Ishimi Y, Komamura Kohno Y, Arai K, Masai H. Biochemical activities associated with mouse Mcm2 protein. J Biol Chem. 2001;276:42744-52 pubmed
    ..Finally, we identified a region required for the nuclear localization of Mcm2. The function of Mcm2 is discussed based on these biochemical characteristics. ..
  4. request reprint
    Ishimi Y, Komamura Kohno Y, Kwon H, Yamada K, Nakanishi M. Identification of MCM4 as a target of the DNA replication block checkpoint system. J Biol Chem. 2003;278:24644-50 pubmed
  5. request reprint
    Ishimi Y, Komamura Kohno Y, Karasawa Shimizu K, Yamada K. Levels of MCM4 phosphorylation and DNA synthesis in DNA replication block checkpoint control. J Struct Biol. 2004;146:234-41 pubmed
    ..These results are consistent with the notion that the phosphorylation of MCM4 is involved in regulation of DNA synthesis in the checkpoint control. ..