H Tonouchi

Summary

Affiliation: Mie University
Country: Japan

Publications

  1. ncbi request reprint Profile of monocyte chemoattractant protein-1 circulating levels in gastric cancer patients
    H Tonouchi
    Dept of Innovative Surgery, Mie University Medical School, Tsu, Japan
    Scand J Gastroenterol 37:830-3. 2002
  2. ncbi request reprint Laparoscopy-assisted distal gastrectomy with laparoscopic sentinel lymph node biopsy after endoscopic mucosal resection for early gastric cancer
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu City, Mie, 514 8507, Japan
    Surg Endosc 21:1289-93. 2007
  3. ncbi request reprint Circulating level of hepatocyte growth factor as a useful tumor marker in patients with early-stage gastric carcinoma
    K Tanaka
    Second Dept of Surgery and Dept of Innovative Surgery, Mie University School of Medicine, Mie, Japan
    Scand J Gastroenterol 39:754-60. 2004
  4. ncbi request reprint Modified pharmacokinetic modulating chemotherapy using 5-fluorouracil, UFT, and taxotere (docetaxel) for advanced gastric cancer
    Kouji Tanaka
    The Second Department of Surgery, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Int J Clin Oncol 8:381-5. 2003
  5. ncbi request reprint 5-FU improves p27-related poor prognosis in patients with Astler-Coller B2-C colorectal carcinoma
    Minako Kobayashi
    Second Department of Surgery, Mie University Medical School, Mie 514 8507, Japan
    Oncol Rep 9:29-33. 2002
  6. doi request reprint Mitotic checkpoint genes, hsMAD2 and BubR1, in oesophageal squamous cancer cells and their association with 5-fluorouracil and cisplatin-based radiochemotherapy
    K Tanaka
    Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Edobashi 2 174, Tsu, Mie 514 8507, Japan
    Clin Oncol (R Coll Radiol) 20:639-46. 2008
  7. doi request reprint Incidence and risk factors for hospital-acquired pneumonia after surgery for gastric cancer: results of prospective surveillance
    Yasuhiko Mohri
    Department of Gastrointestinal Surgery and Pediatric Surgery, Mie University Graduate School of Medicine, 2 174, Edobashi, Tsu, Mie 514 8507, Japan
    World J Surg 32:1045-50. 2008
  8. doi request reprint Neurotrophic receptor, tropomyosin-related kinase B as an independent prognostic marker in gastric cancer patients
    Koji Tanaka
    Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Mie, Japan
    J Surg Oncol 99:307-10. 2009
  9. ncbi request reprint Laparoscopic lymphatic mapping and sentinel node biopsies for early-stage gastric cancer: the cause of false negativity
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University School of Medicine, 2 174 Edobashi, Tsu City, Mie 514 8507, Japan
    World J Surg 29:418-21. 2005
  10. doi request reprint Excision-repair cross-complementing 1 predicts response to cisplatin-based neoadjuvant chemoradiotherapy in patients with esophageal squamous cell carcinoma
    Koji Tanaka
    Department of Gastrointestinal and Pediatric Surgery, and Department of Innovative Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Mie 514 8507, Japan
    Mol Med Report 2:903-9. 2009

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Profile of monocyte chemoattractant protein-1 circulating levels in gastric cancer patients
    H Tonouchi
    Dept of Innovative Surgery, Mie University Medical School, Tsu, Japan
    Scand J Gastroenterol 37:830-3. 2002
    ..It acts as an important factor in the cytokine network, which regulates tumor proliferation, whereas the association between serum MCP-1 level and gastric cancer has not yet been clarified...
  2. ncbi request reprint Laparoscopy-assisted distal gastrectomy with laparoscopic sentinel lymph node biopsy after endoscopic mucosal resection for early gastric cancer
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu City, Mie, 514 8507, Japan
    Surg Endosc 21:1289-93. 2007
    ..We report the preliminary results of laparoscopy-assisted distal gastrectomy with laparoscopic sentinel lymph node biopsy after endoscopic mucosal resection...
  3. ncbi request reprint Circulating level of hepatocyte growth factor as a useful tumor marker in patients with early-stage gastric carcinoma
    K Tanaka
    Second Dept of Surgery and Dept of Innovative Surgery, Mie University School of Medicine, Mie, Japan
    Scand J Gastroenterol 39:754-60. 2004
    ..The present study was designed to clarify the clinical significance of the circulating level of hepatocyte growth factor (HGF) as a tumor marker, especially in early-stage gastric cancer patients...
  4. ncbi request reprint Modified pharmacokinetic modulating chemotherapy using 5-fluorouracil, UFT, and taxotere (docetaxel) for advanced gastric cancer
    Kouji Tanaka
    The Second Department of Surgery, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Int J Clin Oncol 8:381-5. 2003
    ..Preoperative PMC plus TXT produced primary tumor downstaging, leading to improved resectability. The responsiveness of metastatic cancer cells in the regional lymph nodes suggested the possibility of nodal downstaging by this regimen...
  5. ncbi request reprint 5-FU improves p27-related poor prognosis in patients with Astler-Coller B2-C colorectal carcinoma
    Minako Kobayashi
    Second Department of Surgery, Mie University Medical School, Mie 514 8507, Japan
    Oncol Rep 9:29-33. 2002
    ..UFT, 5-FU masked compound may improve the p27-related poor prognosis in colorectal cancer patients...
  6. doi request reprint Mitotic checkpoint genes, hsMAD2 and BubR1, in oesophageal squamous cancer cells and their association with 5-fluorouracil and cisplatin-based radiochemotherapy
    K Tanaka
    Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Edobashi 2 174, Tsu, Mie 514 8507, Japan
    Clin Oncol (R Coll Radiol) 20:639-46. 2008
    ..We also investigated responses to 5-fluorouracil and cisplatin-based radiochemotherapy in ESCC patients...
  7. doi request reprint Incidence and risk factors for hospital-acquired pneumonia after surgery for gastric cancer: results of prospective surveillance
    Yasuhiko Mohri
    Department of Gastrointestinal Surgery and Pediatric Surgery, Mie University Graduate School of Medicine, 2 174, Edobashi, Tsu, Mie 514 8507, Japan
    World J Surg 32:1045-50. 2008
    ..The aim of this study was to determine the incidence and risk factors for HAP after elective surgery for gastric cancer...
  8. doi request reprint Neurotrophic receptor, tropomyosin-related kinase B as an independent prognostic marker in gastric cancer patients
    Koji Tanaka
    Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Mie, Japan
    J Surg Oncol 99:307-10. 2009
    ..Recent studies have focused on the association between metastatic potential and TrkB expression in tumor cells...
  9. ncbi request reprint Laparoscopic lymphatic mapping and sentinel node biopsies for early-stage gastric cancer: the cause of false negativity
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University School of Medicine, 2 174 Edobashi, Tsu City, Mie 514 8507, Japan
    World J Surg 29:418-21. 2005
    ..To apply laparoscopic SN mapping to early-stage gastric cancer patients, the shine-through effect must be eliminated because radiotracers are essential for this method...
  10. doi request reprint Excision-repair cross-complementing 1 predicts response to cisplatin-based neoadjuvant chemoradiotherapy in patients with esophageal squamous cell carcinoma
    Koji Tanaka
    Department of Gastrointestinal and Pediatric Surgery, and Department of Innovative Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Mie 514 8507, Japan
    Mol Med Report 2:903-9. 2009
    ..01). In conclusion, low ERCC1 levels were associated with platinum drug sensitivity in ESCC cell lines. Pre-treatment tumoral ERCC1 may be used as a predictive marker for identifying patients who respond to CRT...
  11. ncbi request reprint Clinical significance of the gene expression profile in residual tumor cells after neoadjuvant chemo-radiotherapy for esophageal cancer
    Koji Tanaka
    Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Mie 514 8507, Japan
    Oncol Rep 21:1489-94. 2009
    ..Gene expression analysis of residual tumor cells in FFPE specimens may be useful when selecting a second line chemotherapy regimen for recurrent esophageal cancer after CRT...
  12. ncbi request reprint Laparoscopically assisted total gastrectomy with sentinel node biopsy for early gastric cancer: preliminary results
    Kouji Tanaka
    Second Department of Surgery, Mie University School of Medicine, Tsu, Mie, Japan
    Am Surg 70:976-81. 2004
    ..This combination treatment is a promising alternative to laparoscopic gastrectomy with conventional lymphadenectomy...
  13. ncbi request reprint The clinical implication of 14-3-3 sigma expression in primary gastrointestinal malignancy
    Kouji Tanaka
    The Second Department of Surgery, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Int J Oncol 25:1591-7. 2004
    ....
  14. ncbi request reprint Prospective study of arterial infusion chemotherapy followed by radiofrequency ablation for the treatment of liver metastasis of gastric cancer
    Koichiro Yamakado
    Department of Radiology, Mie University School of Medicine, Edobashi, Tsu, Japan
    J Vasc Interv Radiol 16:1747-51. 2005
    ..RF ablation was performed for all residual liver tumors, resulting in complete tumor necrosis. All but one patient are still living without intrahepatic recurrence, with a median survival time of 16.5 months...
  15. ncbi request reprint Lymphatic mapping and sentinel node biopsy during laparoscopic gastrectomy for early cancer
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University Medical School, Tsu, Japan
    Dig Surg 20:421-7. 2003
    ..We examined the feasibility and accuracy of laparoscopic lymphatic mapping in predicting lymph node status in patients with gastric cancer...
  16. ncbi request reprint Randomized clinical trial of single- versus multiple-dose antimicrobial prophylaxis in gastric cancer surgery
    Y Mohri
    Department of Gastrointestinal Surgery and Paediatric Surgery, Mie University Graduate School of Medicine, Tsu, Mie, Japan
    Br J Surg 94:683-8. 2007
    ..This multicentre randomized clinical trial compared a single-dose with a multiple-dose regimen of antimicrobial prophylaxis for prevention of surgical-site infection...
  17. ncbi request reprint Hemidouble stapling for esophagogastrostomy during laparoscopically assisted proximal gastrectomy
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University School of Medicine, 2 174 Edobashi, Tsu City, Mie 514 8507, Japan
    Surg Laparosc Endosc Percutan Tech 16:242-4. 2006
    ..Any surgeon can perform a reproducible anastomosis because the place pierced with the center rod is fixed. This technique is easy and safety to operate via minilaparotomy...
  18. ncbi request reprint Ultrasonically activated shears in gastrectomy for large gastric cancers
    Yasuhiko Mohri
    Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie, Japan
    Surg Today 37:1060-3. 2007
    ..We assessed the safety and efficacy of ultrasonic dissection compared with standard electrosurgery in gastrectomy for large gastric cancers, which is associated with high morbidity...
  19. ncbi request reprint Vascular endothelial growth factor as an age-dependent prognostic factor in gastric cancer patients
    Eiji Minato
    Second Department of Surgery, Mie University School of Medicine, Edobashi 2 174, Tsu, 514 8507, Mie, Japan
    Am J Surg 184:460-4. 2002
    ..We investigated whether vascular endothelial growth factor (VEGF) plays an important role in maintaining constant tumor growth in wasted elderly patients, in whom oxygen and glucose supply are often unable to meet the demands of the body...
  20. ncbi request reprint Postoperative weight loss during hospital stays in patients with gastric cancer undergoing surgical resection
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University Graduate School of Medicine, Tsu City, Japan
    Hepatogastroenterology 55:803-6. 2008
    ..The purposes of this report were to identify the clinical variables related to postoperative weight loss during the hospital stay in gastric cancer patients and to investigate the influence of the weight loss on the long-term survival...
  21. ncbi request reprint Spontaneous regression of a metastatic liver tumor: report of a case
    Shin ichi Ikuta
    Second Department of Surgery, Mie University Medical School, 2 174 Edobashi, Tsu 514 8507, Japan
    Surg Today 32:844-8. 2002
    ..We herein describe this rare case and discuss some of the reasons potentially responsible for the regression...
  22. ncbi request reprint Diagnostic sensitivity of contrast swallow for leakage after gastric resection
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University, Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    World J Surg 31:128-31. 2007
    ..We examined the clinical manifestations and computed tomography findings of patients with leakage after gastrectomy for cancer and determined the sensitivity of the contrast swallow for the leakage diagnosis...
  23. ncbi request reprint Clinicopathological features and prognosis of gastric cancer patients > or =75 years of age after laparotomy
    Yasuhiko Mohri
    Department of Gastrointestinal and Pediatric Surgery, Tsu, Mie, Japan
    Int Surg 94:38-42. 2009
    ..0017). Our findings support that gastric cancer in elderly patients warrants surgical resection because the benefits with regard to early and long-term outcomes are the same as for younger patients...
  24. ncbi request reprint Successful treatment of refractory hepatic lymphorrhea after gastrectomy for early gastric cancer, using surgical ligation and subsequent OK-432 (Picibanil) sclerotherapy
    Kouji Tanaka
    The Second Department of Surgery, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Gastric Cancer 7:117-21. 2004
    ..We review 18 cases, including the present case, with respect to the management of postoperative lymphorrhea refractory to conventional medical treatment...
  25. ncbi request reprint Laparoscopic intragastric surgery using GelPort
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University School of Medicine, Mie, Japan
    J Laparoendosc Adv Surg Tech A 16:146-8. 2006
    ..We believe that the technique described here is easier and saves time compared with inserting trocars and closing trocar sites laparoscopically...
  26. ncbi request reprint Fatal and non-fatal complications after surgical resection for gastric cancer
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University School of Medicine, Japan
    Hepatogastroenterology 53:145-9. 2006
    ..We divided overall complications after surgical resection for gastric cancer into fatal and non-fatal, and examined them in view of risk factors. Next we examined the meaning of dividing complications into two groups...
  27. ncbi request reprint Trocar site hernia
    Hitoshi Tonouchi
    Departments of Innovative Surgery, Mie University School of Medicine, Mie, Japan
    Arch Surg 139:1248-56. 2004
    ..To review the relationship between the pathogenesis and clinical manifestations of trocar site hernias seeking to confirm the definition of trocar site hernias by classification...
  28. ncbi request reprint Usefulness of a single trocar for intrathoracic anastomosis during open thoracic surgery for esophageal cancer
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University School of Medicine, Edobashi 2 174, Tsu City, Mie 514 8507, Japan
    Am J Surg 189:240-2. 2005
    ..Moreover, we can adjust the resectional angle with this instrument by using the bending mechanism in its shaft. Furthermore, we can reuse the trocar site for the chest tube...
  29. ncbi request reprint Serum immunosuppressive acidic protein as an interleukin-6 related index of deteriorating condition in gastric cancer patients
    Shin ichi Ikuta
    Second Department of Surgery, Mie University School of Medicine, Mie, Japan
    Dig Surg 20:532-8. 2003
    ..The present study aims to investigate the significance of serum IAP as an index of cytokine-related disease status in gastric cancer patients...
  30. ncbi request reprint Urinary excretion of deoxypyridinoline increases after gastrointestinal surgery
    Tomiko Kani
    Department of Clinical Nutrition, Mie University Hospital, Tsu City, Mie, Japan
    Nutrition 19:747-53. 2003
    ..We investigated the effect of gastrointestinal surgery on bone metabolism with special reference to nutrition status and the systemic inflammatory response (SIR)...
  31. ncbi request reprint Administration sequence-dependent antitumor effects of paclitaxel and 5-fluorouracil in the human gastric cancer cell line MKN45
    Yuji Toiyama
    The Second Department of Surgery, Mie University School of Medicine, Tsu, Mie, Japan
    Cancer Chemother Pharmacol 57:368-75. 2006
    ..The clinical outcome of gastric cancer patients has been improved by combination of 5-fluorouracil (5-FU) and paclitaxel (PXL). However, the optimal schedule of this combination has not been determined...
  32. ncbi request reprint Allogenic blood transfusion is an independent risk factor for infective complications after less invasive gastrointestinal surgery
    Shin ichi Ikuta
    Second Department of Surgery, Mie University School of Medicine, Edobashi 2 174, Tsu, Japan
    Am J Surg 185:188-93. 2003
    ..The present study aimed to clarify the predisposing factors for postoperative infectious complications after less invasive surgery...
  33. ncbi request reprint Operative morbidity associated with groin dissections
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Surg Today 34:413-8. 2004
    ..We sought to quantify the hospital complications after groin dissection, and to identify the patient- and procedure-related factors affecting these complications...
  34. ncbi request reprint Intra-tumoral interleukin-6 down-regulation system and genetic mutations of tumor suppressor genes in colorectal carcinoma
    Chikao Miki
    Second Department of Surgery, Mie University School of Medicine, Tsu, Japan
    Cancer 94:1584-92. 2002
    ..The current study evaluated this down-regulation system in colorectal carcinoma and its relation to the genetic alteration of tumor suppressor genes...
  35. ncbi request reprint Successful repair of an aortoesophageal fistula with aneurysm from esophageal diverticulum
    Fuyuhiko Yasuda
    Department of Thoracic and Cardiovascular Surgery and The Second Department of Surgery, Mie University School of Medicine, Tsu, Japan
    Ann Thorac Surg 73:637-9. 2002
    ..In this case, esophageal diverticulum was diagnosed before the development of an aortoesophageal fistula associated with an aneurysm...
  36. ncbi request reprint Bioresorbable hyaluronate-carboxymethylcellulose membrane (Seprafilm) in surgery for rectal carcinoma: a prospective randomized clinical trial
    Masato Kusunoki
    Second Department of Surgery, Mie University School of Medicine, Tsu, Japan
    Surg Today 35:940-5. 2005
    ..To evaluate the effectiveness of Seprafilm in preventing abdominal adhesions after radical resection of rectal carcinoma, and to observe whether Seprafilm had any adverse effects in patients treated with radiotherapy and chemotherapy...
  37. ncbi request reprint Serum monocyte chemoattractant protein-1 in patients with postoperative infectious complications from gastrointestinal surgery for cancer
    Hitoshi Tonouchi
    Department of Innovative Surgery, Mie University School of Medicine, Edobashi 2 174, Tsu City, 514 8507 Mie, Japan
    World J Surg 28:130-6. 2004
    ....