K Nakano

Summary

Affiliation: Mie University
Country: Japan

Publications

  1. ncbi Afferent connections to the ventral striatum from the medial prefrontal cortex (area 25) and the thalamic nuclei in the macaque monkey
    K Nakano
    Department of Anatomy, Faculty of Medicine, Mie University, Japan
    Ann N Y Acad Sci 877:667-70. 1999
  2. ncbi Neural circuits and topographic organization of the basal ganglia and related regions
    K Nakano
    Department of Anatomy, Mie University Faculty of Medicine, Tsu, 514 8507, Mie, Japan
    Brain Dev 22:S5-16. 2000
  3. ncbi Neural circuits and functional organization of the striatum
    K Nakano
    Department of Anatomy, Faculty of Medicine, Mie University, Tsu, Japan
    J Neurol 247:V1-15. 2000
  4. ncbi The globus pallidus sends axons to the thalamic reticular nucleus neurons projecting to the centromedian nucleus of the thalamus: a light and electron microscope study in the cat
    T Kayahara
    Department of Anatomy, Faculty of Medicine, Mie University, Tsu, Japan
    Brain Res Bull 45:623-30. 1998
  5. ncbi Proline- and alanine-rich Ste20-related kinase associates with F-actin and translocates from the cytosol to cytoskeleton upon cellular stresses
    T Tsutsumi
    Department of Anatomy, Mie University School of Medicine, Tsu, Mie 514 8507, Japan
    J Biol Chem 275:9157-62. 2000
  6. ncbi Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia
    H Ushiro
    Department of Anatomy, Mie University School of Medicine, Edobashi 2 174, Mie, Tsu, 514 8507, Japan
    Arch Biochem Biophys 355:233-40. 1998
  7. ncbi Purification and identification of major soluble 40-kDa antigenic protein from Entamoeba histolytica: its application for serodiagnosis of asymptomatic amebiasis
    J Sanuki
    Department of Tropical Medicine and Parasitology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, 160-8582, Tokyo, Japan
    Parasitol Int 50:73-80. 2001
  8. ncbi Rethinking the role of phosducin: light-regulated binding of phosducin to 14-3-3 in rod inner segments
    K Nakano
    Biomedical Engineering, Boston University, 36 Cummington Street, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 98:4693-8. 2001
  9. ncbi Identification and functional analysis of the gene for type I myosin in fission yeast
    M Toya
    Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, Hongo, Tokyo 113 0033, Japan
    Genes Cells 6:187-99. 2001
  10. ncbi PUMA, a novel proapoptotic gene, is induced by p53
    K Nakano
    Regulation of Cell Growth Laboratory, National Cancer Institute at Frederick, Maryland 21702, USA
    Mol Cell 7:683-94. 2001

Collaborators

Detail Information

Publications22

  1. ncbi Afferent connections to the ventral striatum from the medial prefrontal cortex (area 25) and the thalamic nuclei in the macaque monkey
    K Nakano
    Department of Anatomy, Faculty of Medicine, Mie University, Japan
    Ann N Y Acad Sci 877:667-70. 1999
    ..The distribution pattern of retrogradely labeled neurons was similar in the midline-intralaminar thalamic nuclei following injections in the IL and ventral striatum...
  2. ncbi Neural circuits and topographic organization of the basal ganglia and related regions
    K Nakano
    Department of Anatomy, Mie University Faculty of Medicine, Tsu, 514 8507, Mie, Japan
    Brain Dev 22:S5-16. 2000
    ..These connections are thought to be involved in the acquisition and coordination of motor sequences...
  3. ncbi Neural circuits and functional organization of the striatum
    K Nakano
    Department of Anatomy, Faculty of Medicine, Mie University, Tsu, Japan
    J Neurol 247:V1-15. 2000
    ..and in rats. We review here the microcircuitry of the striatum, as well as the convergence and integration between the functionally segregated loops. Finally, we discuss the functional implications of striatal connections...
  4. ncbi The globus pallidus sends axons to the thalamic reticular nucleus neurons projecting to the centromedian nucleus of the thalamus: a light and electron microscope study in the cat
    T Kayahara
    Department of Anatomy, Faculty of Medicine, Mie University, Tsu, Japan
    Brain Res Bull 45:623-30. 1998
    ..The results indicate that GP innervates directly RT nucleus neurons projecting to CM...
  5. ncbi Proline- and alanine-rich Ste20-related kinase associates with F-actin and translocates from the cytosol to cytoskeleton upon cellular stresses
    T Tsutsumi
    Department of Anatomy, Mie University School of Medicine, Tsu, Mie 514 8507, Japan
    J Biol Chem 275:9157-62. 2000
    ..Our results suggest that PASK may be involved in the regulation of the cytoskeleton in response to cellular stresses such as hyperosmotic shock...
  6. ncbi Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia
    H Ushiro
    Department of Anatomy, Mie University School of Medicine, Edobashi 2 174, Mie, Tsu, 514 8507, Japan
    Arch Biochem Biophys 355:233-40. 1998
    ..Subcellular fractionation showed that PASK was present in both the cytosol and the Triton X-100-insoluble cytoskeletal fraction in brain...
  7. ncbi Purification and identification of major soluble 40-kDa antigenic protein from Entamoeba histolytica: its application for serodiagnosis of asymptomatic amebiasis
    J Sanuki
    Department of Tropical Medicine and Parasitology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, 160-8582, Tokyo, Japan
    Parasitol Int 50:73-80. 2001
    ..These results suggest that the purified protein is applicable antigen for serodiagnostic screening of asymptomatic amebiasis humans...
  8. ncbi Rethinking the role of phosducin: light-regulated binding of phosducin to 14-3-3 in rod inner segments
    K Nakano
    Biomedical Engineering, Boston University, 36 Cummington Street, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 98:4693-8. 2001
    ..By dissociating the Pd/14-3-3 complex, light enables both proteins to function in this role...
  9. ncbi Identification and functional analysis of the gene for type I myosin in fission yeast
    M Toya
    Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, Hongo, Tokyo 113 0033, Japan
    Genes Cells 6:187-99. 2001
    ..In the budding yeast, two myosin I species have been identified and their role in F-actin assembly has been inferred...
  10. ncbi PUMA, a novel proapoptotic gene, is induced by p53
    K Nakano
    Regulation of Cell Growth Laboratory, National Cancer Institute at Frederick, Maryland 21702, USA
    Mol Cell 7:683-94. 2001
    ..Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway...
  11. ncbi Gene cloning, expression, and crystallization of a thermostable exo-inulinase from Geobacillus stearothermophilus KP1289
    Y Tsujimoto
    Department of Applied Biochemistry, Kyoto Prefectural University, Shimogamo, Sakyo, 606 8522, Kyoto, Japan
    Appl Microbiol Biotechnol 62:180-5. 2003
    ..The properties were identical to those of the native enzyme. Additionally, for the first time for a prokaryotic GH32 protein, crystals of the recombinant enzyme were obtained...
  12. ncbi NESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesis
    K Nakano
    Department of Life Science, Faculty of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta, Midori ku, Yokohama 226 8501, Japan
    J Biol Chem 275:20533-9. 2000
    ..These results suggest that NESK, a novel activator of the JNK pathway, functions in coupling TRAF2 to the MEKK1 --> MKK4 --> JNK kinase cascade during the late stages of mammalian embryogenesis...
  13. ncbi Molecular cloning of dihydrolipoamide acetyltransferase of the rat pyruvate dehydrogenase complex: sequence comparison and evolutionary relationship to other dihydrolipoamide acyltransferases
    S Matuda
    Department of Biology, Kanoya National Institute of Fitness and Sports, Japan
    Biochim Biophys Acta 1131:114-8. 1992
    ..The E2 components of the three alpha-ketoacid dehydrogenase complexes are suggested to be classified into three clusters separated during evolution...
  14. ncbi Purification and molecular cloning of succinyltransferase of the rat alpha-ketoglutarate dehydrogenase complex. Absence of a sequence motif of the putative E3 and/or E1 binding site
    K Nakano
    Department of Biochemistry, Kagoshima Women s Junior College, Japan
    J Biol Chem 266:19013-7. 1991
    ..These results show that the rat succinyltransferase does not have the sequence motif of the putative E3- and/or E1-binding site...
  15. ncbi Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution
    M F Browner
    Department of Biochemistry, University of California, San Francisco 94143
    Proc Natl Acad Sci U S A 86:1443-7. 1989
    ..Overall the unphosphorylated protein has a charge of -13, while the fully phosphorylated inactive protein has a net charge of -31. The importance of the asymmetrical charge distribution is discussed...
  16. ncbi Complete cDNA sequence for rabbit muscle glycogen phosphorylase
    K Nakano
    FEBS Lett 204:283-7. 1986
    ..Eight differences between the deduced amino acid sequence and the previously determined protein sequence are discussed...
  17. ncbi Analysis of a suppressor mutation ssb (kinC) of sur0B20 (spo0A) mutation in Bacillus subtilis reveals that kinC encodes a histidine protein kinase
    K Kobayashi
    Department of Applied Biological Science, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Japan
    J Bacteriol 177:176-82. 1995
    ..DNase I protection experiments showed that the Spo0A protein binds to two adjoining sites in the kinC promoter region with different affinities. These results suggest that kinC expression might be regulated by Spo0A...
  18. ncbi Human dihydrolipoamide succinyltransferase: cDNA cloning and localization on chromosome 14q24.2-q24.3
    K Nakano
    Department of Biochemistry, Kagoshima Women s Junior College, Japan
    Biochim Biophys Acta 1216:360-8. 1993
    ..Interestingly, the gene for the dihydrolipoamide acyltransferase of the branched chain alpha-keto acid dehydrogenase complex is also located on chromosome 1p31 (Zneimer et al. (1991) Genomics 10, 740-747)...
  19. ncbi Identification of Myo3, a second type-II myosin heavy chain in the fission yeast Schizosaccharomyces pombe
    F Motegi
    Department of Life Sciences, Graduate School of Arts and Sciences, University of Tokyo, Japan
    FEBS Lett 420:161-6. 1997
    ..Moreover, the function of Myo2 can be replaced by overexpressed Myo3. We observed a modest synthetic interaction between Myo2 and Myo3. Thus, Myo2 and Myo3 seem to cooperate in the formation of the F-actin ring in S. pombe...
  20. ncbi The small GTP-binding protein Rho1 is a multifunctional protein that regulates actin localization, cell polarity, and septum formation in the fission yeast Schizosaccharomyces pombe
    K Nakano
    Graduate Program in Biophysics and Biochemistry, School of Science, University of Tokyo, Hongo, Japan
    Genes Cells 2:679-94. 1997
    ..We have previously isolated two rho genes, rho1+ and rho2+, from the fission yeast Schizosaccharomyces pombe in order to investigate the function of Rho using genetic techniques. In this paper, we report the cellular function of Rho1...
  21. ncbi Increased expression of 3-hydroxyanthranilate 3,4-dioxygenase gene in brain of epilepsy-prone El mice
    Y Nakagawa
    Nagoya University Bioscience Center, Chikusa, Nagoya 464 8601, Japan
    Brain Res Mol Brain Res 58:132-7. 1998
    ..These results suggest that a genetic defect leading to derepression of the 3-HAO gene expression in the brain may be involved in the pathogenesis for the epileptic diseases of El mice...
  22. ncbi HSV trafficking and development of gene therapy vectors with applications in the nervous system
    A R Frampton
    Department of Molecular Genetics and Biochemistry, School of Medicine, University of Pittsburgh, PA 15261, USA
    Gene Ther 12:891-901. 2005
    ..These findings demonstrate the importance of understanding basic virology in the design of vector systems and the powerful approach of exploiting favorable properties of the parent virus in the generation of gene transfer vectors...