Kyoko Imanaka-Yoshida

Summary

Affiliation: Mie University
Country: Japan

Publications

  1. ncbi request reprint Tenascin-C in cardiovascular tissue remodeling: from development to inflammation and repair
    Kyoko Imanaka-Yoshida
    Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine, Tsu, Japan
    Circ J 76:2513-20. 2012
  2. ncbi request reprint The dynamic expression of tenascin-C and tenascin-X during early heart development in the mouse
    Kyoko Imanaka-Yoshida
    Department of Pathology, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507 Japan
    Differentiation 71:291-8. 2003
  3. ncbi request reprint Tenascin-C is a useful marker for disease activity in myocarditis
    Kyoko Imanaka-Yoshida
    Department of Pathology, Mie University School of Medicine, Japan
    J Pathol 197:388-94. 2002
  4. ncbi request reprint Myofibrillogenesis in precardiac mesoderm explant culture
    K Imanaka-Yoshida
    Department of Pathology, Mie University, School of Medicine, Japan
    Cell Struct Funct 22:45-9. 1997
  5. ncbi request reprint Serial extracellular matrix changes in neointimal lesions of human coronary artery after percutaneous transluminal coronary angioplasty: clinical significance of early tenascin-C expression
    K Imanaka-Yoshida
    Department of Pathology, Mie University School of Medicine, Tsu, Japan
    Virchows Arch 439:185-90. 2001
  6. ncbi request reprint Tenascin-C modulates adhesion of cardiomyocytes to extracellular matrix during tissue remodeling after myocardial infarction
    K Imanaka-Yoshida
    Department of Pathology, Mie University School of Medicine, Mie, Japan
    Lab Invest 81:1015-24. 2001
  7. ncbi request reprint Vinculin, Talin, Integrin alpha6beta1 and laminin can serve as components of attachment complex mediating contraction force transmission from cardiomyocytes to extracellular matrix
    K Imanaka-Yoshida
    Department of Pathology, Mie University, School of Medicine, Tsu, Japan
    Cell Motil Cytoskeleton 42:1-11. 1999
  8. ncbi request reprint N-cadherin is required for the differentiation and initial myofibrillogenesis of chick cardiomyocytes
    K Imanaka-Yoshida
    Department of Pathology, Mie University, School of Medicine, Tsu, Japan
    Cell Motil Cytoskeleton 39:52-62. 1998
  9. doi request reprint Basic fibroblast growth factor slow release stent graft for endovascular aortic aneurysm repair: a canine model experiment
    Masaki Kajimoto
    Department of Thoracic and Cardiovascular Surgery, Mie University, Graduate School of Medicine, Tsu, Japan
    J Vasc Surg 48:1306-14. 2008
  10. pmc Involvement of large tenascin-C splice variants in breast cancer progression
    Takatsugu Tsunoda
    Department of Pathology, Mie University School of Medicine, Mie, Japan
    Am J Pathol 162:1857-67. 2003

Detail Information

Publications63

  1. ncbi request reprint Tenascin-C in cardiovascular tissue remodeling: from development to inflammation and repair
    Kyoko Imanaka-Yoshida
    Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine, Tsu, Japan
    Circ J 76:2513-20. 2012
    ..TN-C could exert both harmful and protective effects and might be a therapeutic target as a key molecule in the control of the balance of beneficial and undesirable cellular responses during tissue remodeling...
  2. ncbi request reprint The dynamic expression of tenascin-C and tenascin-X during early heart development in the mouse
    Kyoko Imanaka-Yoshida
    Department of Pathology, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507 Japan
    Differentiation 71:291-8. 2003
    ....
  3. ncbi request reprint Tenascin-C is a useful marker for disease activity in myocarditis
    Kyoko Imanaka-Yoshida
    Department of Pathology, Mie University School of Medicine, Japan
    J Pathol 197:388-94. 2002
    ..Interstitial fibroblasts were the major source of TNC, expressing the large isoform containing alternative splicing sites. These data demonstrate that TNC is a useful marker for evaluation of disease activity in myocarditis...
  4. ncbi request reprint Myofibrillogenesis in precardiac mesoderm explant culture
    K Imanaka-Yoshida
    Department of Pathology, Mie University, School of Medicine, Japan
    Cell Struct Funct 22:45-9. 1997
    ..The precardiac cells differentiated and formed well organized myofibrils in culture. The myofibrillogenesis was similar to the reorganizing process of myofibrils in cultured cardiomyocytes from older embryos...
  5. ncbi request reprint Serial extracellular matrix changes in neointimal lesions of human coronary artery after percutaneous transluminal coronary angioplasty: clinical significance of early tenascin-C expression
    K Imanaka-Yoshida
    Department of Pathology, Mie University School of Medicine, Tsu, Japan
    Virchows Arch 439:185-90. 2001
    ..Our results demonstrate that the matrix proteins of human restenotic lesions sequentially change after angioplasty and that tenascin-C could be a key molecule in the early stages...
  6. ncbi request reprint Tenascin-C modulates adhesion of cardiomyocytes to extracellular matrix during tissue remodeling after myocardial infarction
    K Imanaka-Yoshida
    Department of Pathology, Mie University School of Medicine, Mie, Japan
    Lab Invest 81:1015-24. 2001
    ....
  7. ncbi request reprint Vinculin, Talin, Integrin alpha6beta1 and laminin can serve as components of attachment complex mediating contraction force transmission from cardiomyocytes to extracellular matrix
    K Imanaka-Yoshida
    Department of Pathology, Mie University, School of Medicine, Tsu, Japan
    Cell Motil Cytoskeleton 42:1-11. 1999
    ..These findings suggest that vinculin, talin, integrin alpha6beta1 and laminin system can be involved in transmission of contraction force to the extracellular matrix...
  8. ncbi request reprint N-cadherin is required for the differentiation and initial myofibrillogenesis of chick cardiomyocytes
    K Imanaka-Yoshida
    Department of Pathology, Mie University, School of Medicine, Tsu, Japan
    Cell Motil Cytoskeleton 39:52-62. 1998
    ....
  9. doi request reprint Basic fibroblast growth factor slow release stent graft for endovascular aortic aneurysm repair: a canine model experiment
    Masaki Kajimoto
    Department of Thoracic and Cardiovascular Surgery, Mie University, Graduate School of Medicine, Tsu, Japan
    J Vasc Surg 48:1306-14. 2008
    ..The experimental study was designed to evaluate the effectiveness of stent grafts (S/Gs) with slow release of basic fibroblast growth factor (bFGF) for the organization...
  10. pmc Involvement of large tenascin-C splice variants in breast cancer progression
    Takatsugu Tsunoda
    Department of Pathology, Mie University School of Medicine, Mie, Japan
    Am J Pathol 162:1857-67. 2003
    ..Addition of 4C8MS blocked the function of mFNIII FL. These findings provide strong evidence that the FNIII alternatively spliced region has important roles in tumor progression of breast cancer...
  11. doi request reprint Role of platelet-derived growth factor in cerebral vasospasm after subarachnoid hemorrhage in rats
    Masato Shiba
    Department of Neurosurgery, Mie University Graduate School of Medicine, Mie, Japan
    Acta Neurochir Suppl 115:219-23. 2013
    ..In this study, we examined the effects of PDGF receptor (PDGFR) inactivation on cerebral vasospasm in the endovascular perforation model of SAH in rats...
  12. ncbi request reprint Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation
    Tomohiro Nishioka
    Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine, Tsu, Japan
    J Cardiovasc Pharmacol 49:261-8. 2007
    ....
  13. ncbi request reprint Development of a new method for endovascular aortic repair: combination therapy of cell transplantation and stent grafts with a drug delivery system
    Masaki Kajimoto
    Department of Thoracic and Cardiovascular Surgery, Mie University, Graduate School of Medicine, 2 174, Edobashi, Tsu, Mie 514 8507, Japan
    Circulation 114:I378-83. 2006
    ..Here, we evaluated the effects of cell transplantation combined with bFGF slow release on canine thoracic aortic aneurysmal sacs after S/Gs repair...
  14. ncbi request reprint Tenascin-C synthesized in both donor grafts and recipients accelerates artery graft stenosis
    Yasuhiro Sawada
    Department of Thoracic and Cardiovascular Surgery, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Cardiovasc Res 74:366-76. 2007
    ..In this study, the direct contribution of tenascin-C to neointimal hyperplasia of free artery grafts and the origin of tenascin-C-producing cells were examined using tenascin-C transgenic mice...
  15. ncbi request reprint Tenascin-C upregulates matrix metalloproteinase-9 in breast cancer cells: direct and synergistic effects with transforming growth factor beta1
    Ilunga Kalembeyi
    Department of Pathology, Mie University School of Medicine, Tsu, Mie, Japan
    Int J Cancer 105:53-60. 2003
    ..Thus, TN-C induces MMP-9 expression directly and by collaboration with TGF-beta. These findings reveal a novel role of TN-C in breast cancer progression...
  16. ncbi request reprint Locally applied cilostazol suppresses neointimal hyperplasia and medial thickening in a vein graft model
    Kiyohito Yamamoto
    Department of Thoracic and Cardiovascular Surgery, Mie University Graduate School of Medicine, Tsu, Japan
    Ann Thorac Cardiovasc Surg 13:322-30. 2007
    ..We investigated the inhibitory effect of locally applied cilostazol, an inhibitor of cyclic adenosine monophosphate phosphodiesterase III, on neointimal hyperplasia and medial thickening of the grafts...
  17. ncbi request reprint Candesartan prevents myocardial fibrosis during progression of congestive heart failure
    Katsuya Onishi
    Department of Laboratory Medicine, Mie University School of Medicine, Tsu, Japan
    J Cardiovasc Pharmacol 43:860-7. 2004
    ....
  18. pmc Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury
    Masashi Tamaoki
    Department of Pathology and Biology, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Am J Pathol 167:71-80. 2005
    ..These results indicate that TN-C promotes recruitment of myofibroblasts in the early stages of myocardial repair by stimulating cell migration and differentiation...
  19. doi request reprint Conventional therapy with an ACE inhibitor diminishes left ventricular dyssynchrony during the progression of heart failure
    Tairo Kurita
    Department of Cardiology, Mie University Graduate School of Medicine, Tsu, Japan
    Int J Cardiol 140:48-54. 2010
    ..We hypothesized that an angiotensin converting enzyme (ACE) inhibitor would prevent LV dyssynchrony during the progression of pacing-induced HF through its beneficial effects on hemodynamic change and myocardial fibrosis...
  20. ncbi request reprint Tenascin-C is an essential factor for neointimal hyperplasia after aortotomy in mice
    Kiyohito Yamamoto
    Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, Tsu, Mie 514 8507, Japan
    Cardiovasc Res 65:737-42. 2005
    ..In this study, the direct contribution of tenascin-C to neointimal hyperplasia after aortotomy was examined using tenascin-C-deficient (TNKO) mice...
  21. doi request reprint Imatinib mesylate prevents cerebral vasospasm after subarachnoid hemorrhage via inhibiting tenascin-C expression in rats
    Masato Shiba
    Department of Neurosurgery, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Neurobiol Dis 46:172-9. 2012
    ..This study suggests that imatinib prevents cerebral vasospasm at least partly via inhibiting the upregulation of TNC, implying that TNC may be a new therapeutic target for post-SAH vasospasm...
  22. doi request reprint Tenascin-C induces prolonged constriction of cerebral arteries in rats
    Masashi Fujimoto
    Department of Neurosurgery, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie, Japan
    Neurobiol Dis 55:104-9. 2013
    ..TNC may cause prolonged cerebral arterial constriction via TLR4 and activation of JNK and p38, which may upregulate TLR4. These findings suggest that TNC causes cerebral vasospasm and provides a novel therapeutic approach against it...
  23. doi request reprint Atrial natriuretic peptide gene transfection with a novel envelope vector system ameliorates pulmonary hypertension in rats
    Yoshihide Mitani
    Department of Pediatrics, Mie University Graduate School of Medicine, Tsu, Mie, Japan
    J Thorac Cardiovasc Surg 136:142-9. 2008
    ..We therefore investigated whether intratracheal gene transfer using this vector can induce transgene expression in the lung and whether atrial natriuretic peptide gene transfer ameliorates pulmonary hypertension in rats...
  24. doi request reprint Tenascin-C may aggravate left ventricular remodeling and function after myocardial infarction in mice
    Tomohiro Nishioka
    Dept of Pathology and Matrix Biology, Mie Univ Graduate School of Medicine, Tsu, Japan
    Am J Physiol Heart Circ Physiol 298:H1072-8. 2010
    ..TN-C may thus accelerate adverse ventricular remodeling, cardiac failure, and fibrosis in the residual myocardium after MI...
  25. pmc Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells
    Keiki Nagaharu
    Department of Pathology and Matrix Biology, Graduate School of Medicine, Mie University, Mie, Japan
    Am J Pathol 178:754-63. 2011
    ....
  26. ncbi request reprint A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats
    Hirofumi Sawada
    Department of Pediatric and Developmental Science, Mie University Graduate School of Medicine, Tsu City, Japan
    Chest 132:1265-74. 2007
    ..However, the contribution of NF-kappaB-mediated inflammatory pathways to the development of PH is unknown...
  27. doi request reprint Cerebrospinal fluid tenascin-C in cerebral vasospasm after aneurysmal subarachnoid hemorrhage
    Hidenori Suzuki
    Department of Neurosurgery, Mie University Graduate School of Medicine, Suzuka, Japan
    J Neurosurg Anesthesiol 23:310-7. 2011
    ..This study investigated the association between TNC levels in the cerebrospinal fluid (CSF) and symptomatic vasospasm after aneurysmal subarachnoid hemorrhage (SAH), and the prognostic value of TNC levels...
  28. doi request reprint Matricellular protein: a new player in cerebral vasospasm following subarachnoid hemorrhage
    Hidenori Suzuki
    Department of Neurosurgery, Mie University Graduate School of Medicine, Mie, Japan
    Acta Neurochir Suppl 115:213-8. 2013
    ..Matricellular protein (MCP) is a class of nonstructural and secreted extracellular matrix proteins that exert diverse functions, but its role in vascular smooth muscle contraction has not been investigated...
  29. doi request reprint Role of stromal tenascin-C in mouse prostatic development and epithelial cell differentiation
    Kenichiro Ishii
    Department of Nephro Urologic Surgery and Andrology, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Dev Biol 324:310-9. 2008
    ..Our results suggest that stromal TN-C might be involved in maintaining epithelial cytodifferentiation, morphogenesis, and androgen receptor expression of normal prostate glands in adult mice...
  30. ncbi request reprint Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C
    Amro El-Karef
    Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine, Mie, Japan
    J Hepatol 46:664-73. 2007
    ..Earlier studies have suggested involvement of tenascin-C (TN-C) in liver fibrosis. Here, we examined expression of TN-C variants and types of alternatively spliced fibronectin-type III (FNIII) repeats in chronic hepatitis...
  31. ncbi request reprint Expression of matrix metalloproteinase-3 in mouse endometrial stromal cells during early pregnancy: regulation by interleukin-1alpha and tenascin-C
    Rika Nishiura
    Department of Obstetrics and Gynecology, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Gynecol Endocrinol 21:111-8. 2005
    ..8-fold at 1 ng/ml of IL-1alpha and 3.9 +/- 1.8-fold at 10 mug/ml of TN-C). This study shows that MMP-3 expression is upregulated in endometrial stromal cells of the peri-implantation period and may be controlled by IL-1alpha and TN-C...
  32. doi request reprint Tenascin-C enhances crosstalk signaling of integrin αvβ3/PDGFR-β complex by SRC recruitment promoting PDGF-induced proliferation and migration in smooth muscle cells
    Tomoki Ishigaki
    Department of Pathology and Matrix Biology, Graduate School of Medicine, Mie University, Tsu, Mie, Japan
    J Cell Physiol 226:2617-24. 2011
    ..In the cells on TNC substrate, crosstalk signaling between integrin αvβ3 and PDGFR-β could be amplified by SRC and FAK recruited to focal adhesions, followed by enhanced proliferation and migration of A10 cells by PDGF-BB...
  33. ncbi request reprint Tenascin-C-coated platinum coils for acceleration of organization of cavities and reduction of lumen size in a rat aneurysm model
    Naoki Toma
    Department of Neurosurgery, Mie University School of Medicine, Tsu, Japan
    J Neurosurg 103:681-6. 2005
    ..To reduce the incidence of recurrence by promoting clot organization, the authors designed a platinum coil coated with tenascin-C (TNC), an extracellular matrix glycoprotein, and then histologically examined tissue responses...
  34. doi request reprint Incremental prognostic values of serum tenascin-C levels with blood B-type natriuretic peptide testing at discharge in patients with dilated cardiomyopathy and decompensated heart failure
    Naoki Fujimoto
    Department of Cardiology, Mie University Graduate School of Medicine, Tsu, Japan
    J Card Fail 15:898-905. 2009
    ..This study investigates the predictive value of serum tenascin-C (TN-C), which is observed at the active sites of ongoing tissue remodeling, for cardiac events of patients with dilated cardiomyopathy (DCM)...
  35. ncbi request reprint The targeted disruption of the MYPT1 gene results in embryonic lethality
    Ryuji Okamoto
    The First Department of Internal Medicine, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Transgenic Res 14:337-40. 2005
    ..The point of embryonic lethality is before 7.5 dpc. These findings indicate that MYPT1 is essential for mouse embryogenesis...
  36. ncbi request reprint Method of cell transplantation promoting the organization of intraarterial thrombus
    Koji Hirano
    Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, Tsu, Mie 514 8507, Japan
    Circulation 112:I111-6. 2005
    ..We studied cell transplantation into the aneurismal sac to promote the organization of thrombus for the complete healing of aneurysms...
  37. doi request reprint Tenascin-C causes neuronal apoptosis after subarachnoid hemorrhage in rats
    Masato Shiba
    Department of Neurosurgery, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie, 514 8507, Japan
    Transl Stroke Res 5:238-47. 2014
    ..TNC-induced neuronal apoptosis would be a new target to improve outcome after SAH...
  38. ncbi request reprint Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart
    Ryuji Okamoto
    Department of Cardiology, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Cell Signal 18:1408-16. 2006
    ..Similarity of the two MYPT isoforms suggests common enzymatic mechanisms and regulation. Cardiac myosin is a substrate for the MYPT2 holoenzyme, but the Z-line location raises the possibility of other substrates...
  39. ncbi request reprint Deficiency of tenascin C attenuates allergen-induced bronchial asthma in the mouse
    Hiroki Nakahara
    Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu City, Japan
    Eur J Immunol 36:3334-45. 2006
    ..These observations suggest that TN-C is involved in the pathogenesis of bronchial asthma...
  40. doi request reprint Tenascin-C is induced in cerebral vasospasm after subarachnoid hemorrhage in rats and humans: a pilot study
    Hidenori Suzuki
    Department of Neurosurgery, Graduate School of Medicine, Mie University, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Neurol Res 32:179-84. 2010
    ....
  41. ncbi request reprint MMP-2 expression is associated with rapidly proliferative arteriosclerosis in the flexor tenosynovium and pain severity in carpal tunnel syndrome
    Hitoshi Hirata
    Department of Orthopaedic Surgery, Faculty of Medicine, Mie University Tsu, Mie, Japan
    J Pathol 205:443-50. 2005
    ..Gelatin zymography showed that MMP-2 activity correlated negatively with symptom duration and positively with pain severity...
  42. pmc Co-stimulation of human breast cancer cells with transforming growth factor-beta and tenascin-C enhances matrix metalloproteinase-9 expression and cancer cell invasion
    Kalembeyi Ilunga
    Department of Pathology, Mie University School of Medicine, Mie, Japan
    Int J Exp Pathol 85:373-9. 2004
    ..The in vitro invasion also increased (4-fold). GM6001 inhibited the invasion induced by the co-stimulation. The combined effect of TN-C and TGF-beta resulted in enhanced MMP-9 expression and cancer invasion in vitro...
  43. ncbi request reprint Arrhythmogenic Right Ventricular Cardiomyopathy in a 20-year-old Woman with Systemic Sclerosis
    Kaoru Dohi
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan
    Intern Med 53:973-7. 2014
    ..The patient was ultimately diagnosed with arrhythmogenic RV cardiomyopathy. ..
  44. ncbi request reprint Increased expression of matrix metalloproteinase-2 in nasal polyps
    Alok Bhandari
    Department of Otorhinolaryngology, Mie University School of Medicine, Mie, Japan
    Acta Otolaryngol 124:1165-70. 2004
    ..Matrix metalloproteinases (MMPs) are a family of endopeptidases that can collectively degrade almost all extracellular matrix components. The aim of this study was to investigate the role of MMPs in nasal polyps...
  45. ncbi request reprint Locally applied cilostazol suppresses neointimal hyperplasia by inhibiting tenascin-C synthesis and smooth muscle cell proliferation in free artery grafts
    Kazuya Fujinaga
    Department of Thoracic and Cardiovascular Surgery, Tsu, Japan
    J Thorac Cardiovasc Surg 128:357-63. 2004
    ..CONCLUSION: A single topical administration of cilostazol may suppress neointimal hyperplasia by inhibiting cell proliferation and tenascin-C synthesis in free artery grafts, presenting the potential for clinical use in vascular surgery...
  46. ncbi request reprint Rats with metabolic syndrome resist the protective effects of N-acetyl l-cystein against impaired spermatogenesis induced by high-phosphorus/zinc-free diet
    Yuka Suzuki
    Department of Human Functional Genomics, Life Science Research Center, Mie University, Tsu, Japan
    Exp Toxicol Pathol 65:1173-82. 2013
    ..The lack of the protective effects of NAC on impaired spermatogenesis in SHR/cp could be due to the more pronounced state of oxidative stress observed in these rats compared with WKY. ..
  47. ncbi request reprint Combined angiotensin receptor blocker and ACE inhibitor on myocardial fibrosis and left ventricular stiffness in dogs with heart failure
    Kaoru Funabiki
    Dept of Laboratory Medicine, Mie Univ School of Medicine, 2 174 Edobashi, Tsu 514 8507, Japan
    Am J Physiol Heart Circ Physiol 287:H2487-92. 2004
    ..Thus ARB + ACEI prevents myocardial fibrosis and decreases LV stiffness during the progression of CHF compared with ARB or ACEI alone...
  48. ncbi request reprint Fate of the "opened" arterial duct: Lessons learned from bilateral pulmonary artery banding for hypoplastic left heart syndrome under the continuous infusion of prostaglandin E1
    Yoshihide Mitani
    Department of Pediatrics, Mie University Graduate School of Medicine, Tsu, Mie, Japan
    J Thorac Cardiovasc Surg 133:1653-4. 2007
  49. ncbi request reprint Histopathological findings in a human carotid artery after stent implantation. Case report
    Naoki Toma
    Department of Neurosurgery, Mie University School of Medicine, Tsu, Japan
    J Neurosurg 98:199-204. 2003
    ..The present case provides supportive evidence of stabilized neointima overlying the stent and valuable information regarding morphological characteristics useful for selecting a stent of an appropriate size...
  50. ncbi request reprint Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction
    Shunji Hayashidani
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Am J Physiol Heart Circ Physiol 285:H1229-35. 2003
    ..The inhibition of MMP-2 activation may therefore be a potentially useful therapeutic strategy to manage post-MI hearts...
  51. ncbi request reprint Diagnostic utility of tenascin-C for evaluation of the activity of human acute myocarditis
    Shin ichiro Morimoto
    Division of Cardiology, Department of Internal Medicine, Fujita Health University School of Medicine, Toyoake, Japan
    J Pathol 205:460-7. 2005
    ..These data suggest that TN-C reflects disease activity in cases of human myocarditis. Immunostaining for TN-C could enhance the sensitivity and accuracy of diagnosis using biopsy specimens...
  52. ncbi request reprint Th1-type immune responses by Toll-like receptor 4 signaling are required for the development of myocarditis in mice with BCG-induced myocarditis
    Kimiaki Nishikubo
    Department of Rheumatology, National Hospital Organization, Mie Chuo Medical Center, Mie 514 1101, Japan
    J Autoimmun 29:146-53. 2007
    ..The results suggested that the induction of autoimmune myocarditis by myosin is affected by Th1-type immune responses...
  53. ncbi request reprint A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy
    Masaaki Hayashi
    Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037 1000, USA
    Nat Med 12:128-32. 2006
    ..These findings suggest that Dnaja3 is crucial for mitochondrial biogenesis, at least in part, through its chaperone activity on Polga and provide genetic evidence of the necessity for mitochondrial Hsp40 in preventing DCM...
  54. ncbi request reprint Detection of experimental autoimmune myocarditis in rats by 111In monoclonal antibody specific for tenascin-C
    Mikio Sato
    Department of Cardiovascular Science and Medicine, Graduate School of Medicine, Chiba University, Chiba shi, Chiba, Japan
    Circulation 106:1397-402. 2002
    ..Expression of tenascin-C (TNC), one of the oligometric extracellular glycoproteins, is induced in various pathological states, including inflammation, suggesting that TNC can be a molecular marker of myocarditis...
  55. ncbi request reprint Rho kinases regulate endothelial invasion and migration during valvuloseptal endocardial cushion tissue formation
    Masahide Sakabe
    Department of Anoatomy, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Dev Dyn 235:94-104. 2006
    ..These results suggest that ROCKs have a critical role in the mesenchymal cell invasion/migration that occurs at the late onset of EMT...
  56. ncbi request reprint Serum tenascin-C might be a novel predictor of left ventricular remodeling and prognosis after acute myocardial infarction
    Akira Sato
    Department of Cardiology, Yokosuka Kyosai Hospital, Yokosuka, Japan
    J Am Coll Cardiol 47:2319-25. 2006
    ..We investigated clinical implications of serum tenascin-C (TN-C) levels in patients with acute myocardial infarction (AMI)...
  57. ncbi request reprint Teratogenic effects of bis-diamine on the developing myocardium
    Nobuhiko Okamoto
    Department of Pediatrics, Shiga University of Medical Science, Seta, Otsu, Shiga 520 2192, Japan
    Birth Defects Res A Clin Mol Teratol 70:132-41. 2004
    ..To evaluate the mechanisms of disproportional ventricular development in the anomalous heart, we analyzed the morphology of the embryonic heart and investigated cardiomyocytic DNA synthesis and apoptosis...
  58. ncbi request reprint Noninvasive detection of cardiac repair after acute myocardial infarction in rats by 111 In Fab fragment of monoclonal antibody specific for tenascin-C
    Kenichi Odaka
    Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chiba, Japan
    Int Heart J 49:481-92. 2008
    ....
  59. ncbi request reprint Higher serum tenascin-C levels reflect the severity of heart failure, left ventricular dysfunction and remodeling in patients with dilated cardiomyopathy
    Fumio Terasaki
    Department of Internal Medicine III, Osaka Medical College, Takatsuki, Japan
    Circ J 71:327-30. 2007
    ..Therefore, the expression of TN-C might be useful for detecting the clinical characteristics of, and ventricular remodeling in, dilated cardiomyopathy (DCM)...
  60. doi request reprint Cerebrospinal fluid tenascin-C increases preceding the development of chronic shunt-dependent hydrocephalus after subarachnoid hemorrhage
    Hidenori Suzuki
    Stroke 39:1610-2. 2008
    ..We examined whether the induction of tenascin-C (TN-C), an extracellular matrix glycoprotein known to promote tissue fibrosis, was associated with chronic hydrocephalus after SAH...
  61. ncbi request reprint Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation
    Lei Wei
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA
    Development 129:1705-14. 2002
    ..These results reveal new biological functions for Rho family proteins as essential determinants of cell proliferation signals at looping and chamber maturation stages in mammalian cardiac development...
  62. ncbi request reprint [The role of tenascin C in the development of myocardial remodeling]
    Michiaki Hiroe
    Department of Nephrology and Cardiology, International Medical Center of Japan
    Nihon Rinsho 65:206-13. 2007
  63. ncbi request reprint In vitro model for mouse coronary vasculogenesis
    Noriko Watanabe
    Department of Pediatrics, Shiga University of Medical Science, Shiga, Japan
    Anat Rec A Discov Mol Cell Evol Biol 288:714-22. 2006
    ..These results suggest that PEOs contain precursor cells of coronary vasculature and that vasculogenesis may be simultaneously regulated by multiple factors...