Kazuhiro Umeyama

Summary

Affiliation: Meiji University
Country: Japan

Publications

  1. ncbi Dominant-negative mutant hepatocyte nuclear factor 1alpha induces diabetes in transgenic-cloned pigs
    Kazuhiro Umeyama
    BIOS Research Laboratory Inc, Hiratsuka, Kanagawa 254 0031, Japan
    Transgenic Res 18:697-706. 2009
  2. ncbi The production of a diabetic mouse using constructs encoding porcine insulin promoter-driven mutant human hepatocyte nuclear factor-1alpha
    Masahito Watanabe
    BIOS Research Laboratory Inc, Hiratsuka, Japan
    J Reprod Dev 53:189-200. 2007

Collaborators

  • Masahito Watanabe
  • Hiroshi Nagashima
  • Keizaburo Miki
  • Naoko Izuno
  • Hiro Omi Kawano
  • Hiro-omi Kawano

Detail Information

Publications2

  1. ncbi Dominant-negative mutant hepatocyte nuclear factor 1alpha induces diabetes in transgenic-cloned pigs
    Kazuhiro Umeyama
    BIOS Research Laboratory Inc, Hiratsuka, Kanagawa 254 0031, Japan
    Transgenic Res 18:697-706. 2009
    ..Histochemical analysis of pancreas tissue from the cloned pigs showed small and irregularly formed Langerhans Islets, in which poor insulin secretion was detected...
  2. ncbi The production of a diabetic mouse using constructs encoding porcine insulin promoter-driven mutant human hepatocyte nuclear factor-1alpha
    Masahito Watanabe
    BIOS Research Laboratory Inc, Hiratsuka, Japan
    J Reprod Dev 53:189-200. 2007
    ..These results indicate that HNF1alphaP291 expression driven by the porcine insulin promoter, together with the cytomegalovirus enhancer, induces a diabetic phenotype in transgenic mice...