Research TopicsSpecies | Kazuko MasuoSummaryCountry: Japan Publications
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Publications
Serum uric acid and plasma norepinephrine concentrations predict subsequent weight gain and blood pressure elevationKazuko Masuo
Department of Geriatric Medicine, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita City, Osaka 565 0871, Japan
Hypertension 42:474-80. 2003..These results demonstrate that serum uric acid and plasma norepinephrine concentrations predict subsequent weight gain and blood pressure elevation...
beta2- and beta3-Adrenoceptor polymorphisms relate to subsequent weight gain and blood pressure elevation in obese normotensive individualsHideki Kawaguchi
Department of Geriatric Medicine, Osaka University Graduate School of Medicine, Suita, Japan
Hypertens Res 29:951-9. 2006..beta2- and beta3-adrenoceptor polymorphisms could predict the future BP elevation and further weight gain-induced BP elevation in originally obese subjects...
Obesity-related hypertension: role of the sympathetic nervous system, insulin, and leptinKazuko Masuo
Department of Geriatric Medicine, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita City, Osaka 565 0871 Japan
Curr Hypertens Rep 4:112-8. 2002..A better understanding of the pathophysiologic mechanisms of obesity-related hypertension may help in prevention, treatment, and slowing of the cardiovascular complications of obesity...
Acute hyperinsulinemia reduces plasma leptin levels in insulin-sensitive Japanese menKazuko Masuo
Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
Am J Hypertens 18:235-43. 2005..These conditions are documented as insulin-resistant states with sympathetic overactivity. However, the relation between plasma insulin, leptin levels, and sympathetic nerve activity, especially after meals, has not been established...
High plasma norepinephrine levels associated with beta2-adrenoceptor polymorphisms predict future renal damage in nonobese normotensive individualsKazuko Masuo
Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Australia
Hypertens Res 30:503-11. 2007....
Beta2- and beta3-adrenergic receptor polymorphisms are related to the onset of weight gain and blood pressure elevation over 5 yearsKazuko Masuo
Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
Circulation 111:3429-34. 2005..Functional polymorphisms in the beta2- and beta3-adrenergic receptors have been reported to be associated with hypertension and obesity...
Rebound weight gain as associated with high plasma norepinephrine levels that are mediated through polymorphisms in the beta2-adrenoceptorKazuko Masuo
Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
Am J Hypertens 18:1508-16. 2005..The present study evaluates hormonal mechanisms and the relationship of beta2-adrenoceptor polymorphisms involved in individuals who regain weight after initially successful weight loss...
Beta2-adrenoceptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic activationKazuko Masuo
Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
Am J Hypertens 19:1084-91. 2006..This study examines the associations of beta2-adrenoceptor polymorphism with relationships between plasma norepinephrine (NE) and leptin to evaluate further the mechanisms of obesity...
Gender differences in sympathetic nervous activity: influence of body mass and blood pressureElisabeth Lambert
Human Neurotransmitters Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
J Hypertens 25:1411-9. 2007..We tested whether the sympathetic nervous system was differently affected in men and women by the body mass index (BMI), BP, leptin and weight loss...
Effects of dietary weight loss on sympathetic activity and cardiac risk factors associated with the metabolic syndromeNora E Straznicky
Cardiovascular Nutrition Laboratory, Wynn Domain, Baker Heart Research Institute, P O Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
J Clin Endocrinol Metab 90:5998-6005. 2005....
Beta2-adrenoceptor polymorphisms relate to insulin resistance and sympathetic overactivity as early markers of metabolic disease in nonobese, normotensive individualsKazuko Masuo
Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
Am J Hypertens 18:1009-14. 2005..To clarify the relevance of the beta-adrenergic receptor polymorphisms to insulin resistance, we studied their association with polymorphisms of beta2 (Arg16Gly, Gln27Glu) and beta3 (Trp64Arg) adrenoceptor genes...
Lys418Asn polymorphism of the alpha2-adrenoceptor gene relates to serum uric acid levels but not to insulin sensitivityKazuko Masuo
Human Neurotransmitter Laboratory, Baker Heart Research Institute, PO Box 6492 St Kilda Rd Central, Melbourne, Victoria 8008, Australia
Hypertension 46:144-50. 2005..Although hyperuricemia is of known relevance to insulin resistance, it appears to have different genetic determinants from insulin resistance in terms of adrenoceptor polymorphisms...
Leptin-receptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic nerve activation in a Caucasian male populationKazuko Masuo
Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Australia
Hypertens Res 31:1093-100. 2008..We therefore hypothesize that leptin-receptor play a role in the development of obesity through leptin resistance and blunted leptin-mediated sympathetic nerve activity...
