Hitoshi Masaki

Summary

Country: Japan

Publications

  1. doi request reprint Role of antioxidants in the skin: anti-aging effects
    Hitoshi Masaki
    Nikkol Group Cosmos Technical Center Co, Ltd, 3 24 3 Hasune, Itabashi ku, Tokyo 174 0046, Japan
    J Dermatol Sci 58:85-90. 2010
  2. doi request reprint Reactive oxygen species in HaCaT keratinocytes after UVB irradiation are triggered by intracellular Ca(2+) levels
    Hitoshi Masaki
    Cosmos Technical Center Co, Ltd, 3 24 3 Hasune, Itabashi ku, Tokyo, Japan
    J Investig Dermatol Symp Proc 14:50-2. 2009
  3. ncbi request reprint A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties
    Yasunobu Ochiai
    Cosmos Technical Center Co, Ltd, 3 24 3, Hasune, Itabashi ku, Tokyo 174 0046, Japan
    J Dermatol Sci 44:37-44. 2006
  4. ncbi request reprint Exogenous nitric oxide enhances the synthesis of type I collagen and heat shock protein 47 by normal human dermal fibroblasts
    Kei Obayashi
    Cosmos Technical Center Co Ltd, 3 24 3 Hasune, Itabashi ku, Tokyo 174 0046, Japan
    J Dermatol Sci 41:121-6. 2006
  5. ncbi request reprint L-Ergothioneine scavenges superoxide and singlet oxygen and suppresses TNF-alpha and MMP-1 expression in UV-irradiated human dermal fibroblasts
    Kei Obayashi
    Cosmos Technical Center Co Ltd, 3 24 3, Hasune, Itabashi ku, Tokyo, 174 0046, Japan
    J Cosmet Sci 56:17-27. 2005
  6. ncbi request reprint alpha-tocopherol increases the intracellular glutathione level in HaCaT keratinocytes
    Hitoshi Masaki
    Kobe Research Laboratory, Noevir Co, Ltd, 13 1 Port Island, Naka machi, 6 Chome, Chuo Ku, Kobe 650 8521, Japan
    Free Radic Res 36:705-9. 2002

Collaborators

Detail Information

Publications6

  1. doi request reprint Role of antioxidants in the skin: anti-aging effects
    Hitoshi Masaki
    Nikkol Group Cosmos Technical Center Co, Ltd, 3 24 3 Hasune, Itabashi ku, Tokyo 174 0046, Japan
    J Dermatol Sci 58:85-90. 2010
    ..The effects of ROS generated in the skin and the roles of ROS in altering the skin are also discussed. In addition, the effects of representative antioxidants on the skin are summarized with a focus on skin aging...
  2. doi request reprint Reactive oxygen species in HaCaT keratinocytes after UVB irradiation are triggered by intracellular Ca(2+) levels
    Hitoshi Masaki
    Cosmos Technical Center Co, Ltd, 3 24 3 Hasune, Itabashi ku, Tokyo, Japan
    J Investig Dermatol Symp Proc 14:50-2. 2009
    ..This suggests that intracellular Ca(2+) is the first trigger for UVB-induced ROS generation.Journal of Investigative Dermatology Symposium Proceedings (2009) 14, 50-52; doi:10.1038/jidsymp.2009.12...
  3. ncbi request reprint A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties
    Yasunobu Ochiai
    Cosmos Technical Center Co, Ltd, 3 24 3, Hasune, Itabashi ku, Tokyo 174 0046, Japan
    J Dermatol Sci 44:37-44. 2006
    ..However, Vitamin C has limited stability and permeability, and development of a Vitamin C derivative with improved properties is needed...
  4. ncbi request reprint Exogenous nitric oxide enhances the synthesis of type I collagen and heat shock protein 47 by normal human dermal fibroblasts
    Kei Obayashi
    Cosmos Technical Center Co Ltd, 3 24 3 Hasune, Itabashi ku, Tokyo 174 0046, Japan
    J Dermatol Sci 41:121-6. 2006
    ..On the other hand, physiological NO is useful to maintain skin homeostasis such as a vasodilatation. However, a role of NO on production of dermal matrix has been clarified...
  5. ncbi request reprint L-Ergothioneine scavenges superoxide and singlet oxygen and suppresses TNF-alpha and MMP-1 expression in UV-irradiated human dermal fibroblasts
    Kei Obayashi
    Cosmos Technical Center Co Ltd, 3 24 3, Hasune, Itabashi ku, Tokyo, 174 0046, Japan
    J Cosmet Sci 56:17-27. 2005
    ..EGT may reduce skin anti-aging effects after UV irradiation by the scavenging of *O(2)(-) and (1)O(2), and reducing signals for protease and inflammatory activity...
  6. ncbi request reprint alpha-tocopherol increases the intracellular glutathione level in HaCaT keratinocytes
    Hitoshi Masaki
    Kobe Research Laboratory, Noevir Co, Ltd, 13 1 Port Island, Naka machi, 6 Chome, Chuo Ku, Kobe 650 8521, Japan
    Free Radic Res 36:705-9. 2002
    ..From these results, it was concluded that alpha-tocopherol increases the intracellular GSH level of HaCaT keratinocytes through the up-regulation of gamma-GCS-HS mRNA...