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Genomes and Genes | Ken YamamotoSummaryAffiliation: Kyushu University Country: Japan Publications
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Publications
Polycomb group suppressor of zeste 12 links heterochromatin protein 1alpha and enhancer of zeste 2Ken Yamamoto
Division of Molecular Population Genetics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
J Biol Chem 279:401-6. 2004..In addition SU(Z)12 represses transcription activity in the presence of HP1alpha in a reporter assay. These results provide a molecular explanation for the functional link of these epigenetic silencing processes mediated by Su(z)12...- Self-interaction of heterochromatin protein 1 is required for direct binding to histone methyltransferase, SUV39H1Ken Yamamoto
Division of Molecular Population Genetics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka shi, Fukuoka ken 812 8582, Japan
Biochem Biophys Res Commun 301:287-92. 2003..It seems that self-interaction through the chromo shadow domain of HP1 is crucial for recruitment of SUV39H1 onto nucleosomes... - Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitroKenji Furuno
Division of Molecular Population Genetics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812 8582, Japan
Biochem Biophys Res Commun 345:1051-8. 2006..These results suggest that SUZ12 might have a role in transcriptional regulation through physical interaction with MEP50 that can be an adaptor between PRMT5 and its substrate H2A... - Tissue inhibitor of metalloproteinase 2 and coronary artery lesions in Kawasaki diseaseKenji Furuno
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
J Pediatr 151:155-60, 160.e1. 2007..To identify cytokine genes uniquely expressed in peripheral blood mononuclear cells (PBMNCs) in the acute phase of Kawasaki disease (KD) with coronary artery lesions (CALs)... 
Stomach cancer-derived del223V-226L mutation of the STCH gene causes loss of sensitization to TRAIL-mediated apoptosisNobushige Yamagata
Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
Biochem Biophys Res Commun 376:499-503. 2008..These results suggest that STCH has a role in cell survival via modulation of the TRAIL-mediated cell death pathway...
A definitive haplotype map as determined by genotyping duplicated haploid genomes finds a predominant haplotype preference at copy-number variation eventsYoji Kukita
Division of Genome Analysis, Research Center for Genetic Information, Kyushu University, Fukuoka 812 8582, Japan
Am J Hum Genet 86:918-28. 2010....- Rapid detection of SAG 926delA mutation using real-time polymerase chain reactionShigeo Yoshida
Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Mol Vis 12:1552-7. 2006..Mutation 926delA of the arrestin/S-antigen SAG gene is the main cause of Oguchi disease in the Japanese. The purpose of this study was to develop a rapid diagnostic assay to detect mutations in the SAG gene... - Female agammaglobulinemia due to the Bruton tyrosine kinase deficiency caused by extremely skewed X-chromosome inactivationHidetoshi Takada
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Blood 103:185-7. 2004..This is the first report of female XLA caused by heterozygous BTK gene abnormality and extreme nonrandom inactivation of X chromosome on which normal BTK gene is located... - Association analysis of glutathione-S-transferase P1 (GSTP1) polymorphism with urothelial cancer susceptibility and myelosuppression after M-VAC chemotherapyAkira Yokomizo
Department of Urology, Kyushu University Graduate School of Medical Science, Fukuoka, Japan
Int J Urol 14:500-4. 2007.... - A genetic variant in the gene encoding the stress70 protein chaperone family member STCH is associated with gastric cancer in the Japanese populationMasayuki Aoki
Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812 8582, Japan
Biochem Biophys Res Commun 335:566-74. 2005..0001, odds ratio=1.59). These results suggest that, in the Japanese population, STCH might be a new candidate for conferring susceptibility to this disease... - Multiple lysine methylation of PCAF by Set9 methyltransferaseToshihiro Masatsugu
Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
Biochem Biophys Res Commun 381:22-6. 2009..Our data may lead to a new insight into PCAF functions and provide additional information to identify unknown targets of Set9... - Novel triple missense mutations of GUCY2D gene in Japanese family with cone-rod dystrophy: possible use of genotyping microarrayShigeo Yoshida
Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Mol Vis 12:1558-64. 2006..To report a novel mutation in the GUCY2D gene in a Japanese family with autosomal dominant cone-rod dystrophy (adCORD), and to examine the possible use of arrayed primer extension (APEX)-based genotyping chip in detecting mutations... - Behavioral and clinical correlates of high-sensitivity C-reactive protein in Japanese men and womenAkie Hirata
Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Clin Chem Lab Med 50:1469-76. 2012..Few studies have evaluated relative importance of behavioral and clinical covariates of high-sensitivity C-reactive protein in Japanese population... - Genomic copy number of a carcinogenic single nucleotide polymorphism at 8q24 in non-risk allele colorectal cancer associated with insulin growth factor 2 receptor expressionYusuke Takahashi
Department of Surgical Oncology, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
J Gastroenterol Hepatol 27:95-9. 2012..The association between the SNP genotype and genes associated with diabetes or hyperlipidemia was investigated in cases of CRC... - Mutations of syntaxin 11 and SNAP23 genes as causes of familial hemophagocytic lymphohistiocytosis were not found in Japanese peopleKen Yamamoto
Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
J Hum Genet 50:600-3. 2005..The patients had no mutations and 10% had one polymorphism (146G>A) of syntaxin 11, while no mutation of SNAP23 was observed. Our results indicate that aberrations in the SNARE system may not cause FHL in Japanese families... - Identification of TCTE3 as a gene responsible for congenital diaphragmatic hernia using a high-resolution single-nucleotide polymorphism arrayRisa Teshiba
Division of Genome Analysis, Research Center for Genetic Information, Medical Institute of Bioregulation, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
Pediatr Surg Int 27:193-8. 2011..In this study, we analyzed copy number variants (CNVs) using a single-nucleotide polymorphism (SNP) array to examine whether microdeletions contribute to the pathogenesis of this disease... - P300/CBP-associated factor regulates Y-box binding protein-1 expression and promotes cancer cell growth, cancer invasion and drug resistanceMasaki Shiota
Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Cancer Sci 101:1797-806. 2010..The present data suggest that Twist1 and YB-1 as well as PCAF may be promising molecular therapeutic targets... - The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancerYasushi Takatsuno
Department of Surgical Oncology, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
Ann Surg Oncol 20:1395-402. 2013..21, may affect copy number aberrations and/or expression profiles in colorectal cancer (CRC). We investigated the role of this single nucleotide polymorphism in the clinical outcome of CRC... - Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13-p12 in JapaneseHajime Nawata
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
J Hum Genet 49:629-34. 2004..These results taken together suggest that a susceptibility gene for type 2 diabetes mellitus in Japanese will reside in 11p13-p12... - [Genome-wide approach to identify genes involved in gastric cancer]Ken Yamamoto
Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University
Fukuoka Igaku Zasshi 96:25-33. 2005 - SNPs in the promoter of a B cell-specific antisense transcript, SAS-ZFAT, determine susceptibility to autoimmune thyroid diseaseSenji Shirasawa
Department of Pathology, Research Institute, International Medical Center of Japan, Toyama 1 21 1, Shinjuku ku, Tokyo 162 8655, Japan
Hum Mol Genet 13:2221-31. 2004.... - The bromodomain mediates transcriptional intermediary factor 1alpha -nucleosome interactionsEumorphia Remboutsika
Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM Universite Louis Pasteur, BP 163, F 67404 Illkirch Cedex, France
J Biol Chem 277:50318-25. 2002..Based on our results, we propose that the BrD plays a critical role in vivo by directing transregulators to their cognate location on nucleosomal DNA... - Replication of genome-wide association studies of type 2 diabetes susceptibility in JapanYukio Horikawa
Department of Diabetes and Endocrinology, Division of Molecule and Structure, Gifu University School of Medicine, Gifu, Japan
J Clin Endocrinol Metab 93:3136-41. 2008.... - Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjectsKazuaki Miyake
Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
J Hum Genet 53:174-80. 2008..However, neither rs11196218 nor rs290487 showed a significant association. These results indicate that TCF7L2 is an important susceptibility gene for type 2 diabetes in the Japanese population... - [Anesthetic management of a patient with severe combined pulmonary disease under epidural anesthesia with spontaneous respiration]Ai Usukura
Department of Anesthesiology, School of Medicine, Kanazawa University, Kanazawa 920 8641
Masui 57:624-7. 2008..No respiratory complications developed postoperatively. Maintaining spontaneous breathing during abdominal surgery using epidural anesthesia and light general anesthesia is a good option for COPD patients... - Which is a better position for insertion of a high thoracic epidural catheter: sitting or lateral decubitus?Masatoshi Nishi
Department of Anesthesiology and Intensive Care Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
J Cardiothorac Vasc Anesth 20:656-8. 2006..The purpose of this study was to compare the safety and success rates associated with the placement of a high thoracic epidural catheter in the sitting vs. the lateral decubitus position... - Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functionsEiichi Ishii
Department of Pediatrics, Faculty of Medicine, Saga University, 5 1 1 Nabeshima, Saga 849 8501, Japan
Blood 105:3442-8. 2005..These results suggest an association between the type of genetic mutation in FHL cases and the magnitude of CTL cytolytic activity and age at onset... - Dynamics of ultrasonically induced birefringence of in rod-like colloidal solutionsTatsuro Matsuoka
Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Chikusa ku, Nagoya 464 8603, Japan
Colloids Surf B Biointerfaces 56:72-9. 2007..For rod-like micelles, the birefringence showed anomalous damping oscillation when the rod-like micelle was in an entangling state. The mechanism of damping oscillation was discussed using the results of the rheological measurements... - Involvement of alpha1-acid glycoprotein in inter-individual variation of disposition kinetics of ropivacaine following epidural infusion in off-pump coronary artery bypass graftingKoichi Yokogawa
Department of Hospital Pharmacy, School of Medicine, Kanazawa University, 13 1, Takara machi, Kanazawa 920 8641, Japan
J Pharm Pharmacol 59:67-73. 2007..However, in combination therapy, it is also important to consider the AGP variant-dependence of the inhibitory effect of concomitantly administered drugs... - Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clonesKenji Yoshida
Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita 565-0871, Japan
Int Immunol 14:1439-47. 2002..The results suggest that our islet-reactive T cell clones recognize in islet beta cells a natural ligand that is similar to these peptides... - Effects of various forms of surfactant protein C on tidal volume in ventilated immature newborn rabbitsKatsumi Tashiro
Department of Anesthesiology and Intensive Care Medicine, Graduate School of Medicine, Kanazawa University, Kanazawa 920 8641, Japan
J Appl Physiol 94:1519-26. 2003..The physiological effect of basic mixture was not improved by monomeric SP-C. We conclude that palmitoyl groups are important for the physiological effects of SP-C and that the dimeric form also improves physiological effects... - A novel perforin gene mutation in a Japanese family with hemophagocytic lymphohistiocytosisIkuyo Ueda
Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
Int J Hematol 83:51-4. 2006....