Futoshi Taura

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint Phytocannabinoids in Cannabis sativa: recent studies on biosynthetic enzymes
    Futoshi Taura
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    Chem Biodivers 4:1649-63. 2007
  2. doi request reprint Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway
    Futoshi Taura
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    FEBS Lett 583:2061-6. 2009
  3. ncbi request reprint Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa
    Futoshi Taura
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    FEBS Lett 581:2929-34. 2007
  4. ncbi request reprint Production of Delta(1)-tetrahydrocannabinolic acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris
    Futoshi Taura
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Biochem Biophys Res Commun 361:675-80. 2007
  5. doi request reprint Expression, purification, and characterization of anti-plumbagin single-chain variable fragment antibody in Sf9 insect cell
    Seiichi Sakamoto
    Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Hybridoma (Larchmt) 29:481-8. 2010
  6. pmc Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa
    Chiho Taguchi
    Faculty of Pharmaceutical Sciences, Kyushu University, Japan
    Acta Crystallogr Sect F Struct Biol Cryst Commun 64:217-20. 2008
  7. doi request reprint Development of sensitivity-improved fluorescence-linked immunosorbent assay using a fluorescent single-domain antibody against the bioactive naphthoquinone, plumbagin
    Seiichi Sakamoto
    Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Anal Bioanal Chem 396:2955-63. 2010
  8. ncbi request reprint The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L
    Supaart Sirikantaramas
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    J Biol Chem 279:39767-74. 2004
  9. ncbi request reprint Identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in Cannabis leaf cells
    Satoshi Morimoto
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Biol Chem 282:20739-51. 2007
  10. doi request reprint Flavone-catalyzed apoptosis in Scutellaria baicalensis
    Motosuke Hirunuma
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Phytochemistry 72:752-60. 2011

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Phytocannabinoids in Cannabis sativa: recent studies on biosynthetic enzymes
    Futoshi Taura
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    Chem Biodivers 4:1649-63. 2007
  2. doi request reprint Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway
    Futoshi Taura
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    FEBS Lett 583:2061-6. 2009
    ..The possibility that OLS could be involved in OLA biosynthesis was discussed based on its catalytic properties and expression profile...
  3. ncbi request reprint Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa
    Futoshi Taura
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    FEBS Lett 581:2929-34. 2007
    ..The structural and functional properties of CBDA synthase are quite similar to those of tetrahydrocannabinolic-acid (THCA) synthase, which is responsible for the biosynthesis of THCA, the major cannabinoid in drug-type Cannabis plants...
  4. ncbi request reprint Production of Delta(1)-tetrahydrocannabinolic acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris
    Futoshi Taura
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Biochem Biophys Res Commun 361:675-80. 2007
    ....
  5. doi request reprint Expression, purification, and characterization of anti-plumbagin single-chain variable fragment antibody in Sf9 insect cell
    Seiichi Sakamoto
    Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Hybridoma (Larchmt) 29:481-8. 2010
    ....
  6. pmc Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa
    Chiho Taguchi
    Faculty of Pharmaceutical Sciences, Kyushu University, Japan
    Acta Crystallogr Sect F Struct Biol Cryst Commun 64:217-20. 2008
    ..55 A resolution and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 54.3, b = 110, c = 130 A. These data will enable us to determine the crystal structure of PKS-1...
  7. doi request reprint Development of sensitivity-improved fluorescence-linked immunosorbent assay using a fluorescent single-domain antibody against the bioactive naphthoquinone, plumbagin
    Seiichi Sakamoto
    Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Anal Bioanal Chem 396:2955-63. 2010
    ..2 microg mL(-1)), indicating that a sensitive immunoassay could be developed by using fluobody instead of monoclonal antibody or scFv...
  8. ncbi request reprint The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L
    Supaart Sirikantaramas
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    J Biol Chem 279:39767-74. 2004
    ..Thus, we concluded that the FAD binding residue is His-114 and that the THCA synthase reaction is FAD-dependent. This is the first report on molecular characterization of an enzyme specific to cannabinoid biosynthesis...
  9. ncbi request reprint Identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in Cannabis leaf cells
    Satoshi Morimoto
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Biol Chem 282:20739-51. 2007
    ..Based on these results, we conclude that CBCA and THCA have the ability to induce necrotic cell death via mitochondrial dysfunction in the leaf cells of C. sativa...
  10. doi request reprint Flavone-catalyzed apoptosis in Scutellaria baicalensis
    Motosuke Hirunuma
    Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Phytochemistry 72:752-60. 2011
    ..Thus, S. baicalensis possesses a unique apoptosis-inducing system that is linked with metabolism of baicalin...
  11. ncbi request reprint Recent advances in Cannabis sativa research: biosynthetic studies and its potential in biotechnology
    Supaart Sirikantaramas
    Graduate School of Pharmaceutical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Curr Pharm Biotechnol 8:237-43. 2007
    ..Transgenic tobacco hairy roots expressing THCA synthase can produce THCA upon feeding of CBGA. These results open the way for biotechnological production of cannabinoids in the future...
  12. ncbi request reprint Tetrahydrocannabinolic acid synthase, the enzyme controlling marijuana psychoactivity, is secreted into the storage cavity of the glandular trichomes
    Supaart Sirikantaramas
    Graduate School of Pharmaceutical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582 Japan
    Plant Cell Physiol 46:1578-82. 2005
    ..These results also showed that secretory cells of the glandular trichomes secrete not only metabolites but also biosynthetic enzyme...
  13. pmc Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq
    Surang Engprasert
    Graduate School of Pharmaceutical Science, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    BMC Plant Biol 4:18. 2004
    ..Therefore, GGPP synthase is thought to be a key enzyme in biosynthesis of forskolin. Herein we report the first confirmation of the GGPP synthase gene in Coleus forskohlii Briq...
  14. pmc Crystallization of Delta1-tetrahydrocannabinolic acid (THCA) synthase from Cannabis sativa
    Yoshinari Shoyama
    Faculty of Pharmaceutical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    Acta Crystallogr Sect F Struct Biol Cryst Commun 61:799-801. 2005
    ..2 A. The calculated Matthews coefficient was approximately 4.1 or 2.0 A3 Da(-1) assuming the presence of one or two molecules of THCA synthase in the asymmetric unit, respectively...
  15. ncbi request reprint Construction and expression of specificity-improved single-chain variable fragments against the bioactive naphthoquinone, plumbagin
    Seiichi Sakamoto
    Department of Medicinal Plants Breeding and Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Biol Pharm Bull 32:434-9. 2009
    ..These notable properties of the recombinant antibody against PL made it possible to develop an enzyme-linked immunosorbent assay (ELISA) for reliable determination of PL...
  16. ncbi request reprint New dimeric morphine from opium poppy (Papaver somuniferum) and its physiological function
    Satoshi Morimoto
    Graduate School of Pharmaceutical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Nat Prod 66:987-9. 2003
    ....