Masakazu Takahara

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint Concurrent double infections of the skin: phaeohyphomycosis and nocardiosis in a patient with idiopathic thrombocytopenic purpura
    Masakazu Takahara
    Department of Dermatology, Hiroshima Red Cross Hospital, Hiroshima, Japan
    J Am Acad Dermatol 53:S277-80. 2005
  2. doi request reprint Desmoplastic fibroblastoma: a case presenting as a protruding nodule in the dermis
    Masakazu Takahara
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Cutan Pathol 35:70-3. 2008
  3. doi request reprint Stromal CD10 expression, as well as increased dermal macrophages and decreased Langerhans cells, are associated with malignant transformation of keratinocytes
    Masakazu Takahara
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Cutan Pathol 36:668-74. 2009
  4. doi request reprint Cathepsin K-upregulation in fibroblasts promotes matrigel invasive ability of squamous cell carcinoma cells via tumor-derived IL-1α
    Lining Xie
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Dermatol Sci 61:45-50. 2011
  5. doi request reprint CD10 expressed by fibroblasts and melanoma cells degrades endothelin-1 secreted by human keratinocytes
    Lining Xie
    Department of Dermatology, Kyushu University, 3 1 1 Maidashi Higashiku, Fukuoka 812 8582, Japan
    Eur J Dermatol 21:505-9. 2011
  6. doi request reprint CD10-bearing fibroblasts may inhibit skin inflammation by down-modulating substance P
    Lining Xie
    Department of Dermatology, Kyushu University, Higashiku, Fukuoka, Japan
    Arch Dermatol Res 303:49-55. 2011
  7. doi request reprint The prognostic value of a reverse transcriptase-PCR assay of sentinel lymph node biopsy for patients with cutaneous melanoma: a single-center analysis in Japan
    Takamichi Ito
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Melanoma Res 22:38-44. 2012
  8. doi request reprint Expression of CD10 predicts tumor progression and unfavorable prognosis in malignant melanoma
    Junna Oba
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Acad Dermatol 65:1152-60. 2011
  9. doi request reprint Levels of the EMT-related protein Snail/Slug are not correlated with p53/p63 in cutaneous squamous cell carcinoma
    Hongxiang Chen
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    J Cutan Pathol 40:651-6. 2013
  10. doi request reprint Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect
    Gaku Tsuji
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Invest Dermatol 132:59-68. 2012

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Concurrent double infections of the skin: phaeohyphomycosis and nocardiosis in a patient with idiopathic thrombocytopenic purpura
    Masakazu Takahara
    Department of Dermatology, Hiroshima Red Cross Hospital, Hiroshima, Japan
    J Am Acad Dermatol 53:S277-80. 2005
    ..We believe that this case represents a novel episode of previously unreported concurrent infections with phaeohyphomycosis and lymphocutaneous nocardiosis in human beings...
  2. doi request reprint Desmoplastic fibroblastoma: a case presenting as a protruding nodule in the dermis
    Masakazu Takahara
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Cutan Pathol 35:70-3. 2008
    ..We diagnosed this case as desmoplastic fibroblastoma arising in the dermis and superficial subcutaneous tissue...
  3. doi request reprint Stromal CD10 expression, as well as increased dermal macrophages and decreased Langerhans cells, are associated with malignant transformation of keratinocytes
    Masakazu Takahara
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Cutan Pathol 36:668-74. 2009
    ..We analyzed CD10+ stromal cells, dermal macrophages and Langerhans cells (LCs) in skin tumors...
  4. doi request reprint Cathepsin K-upregulation in fibroblasts promotes matrigel invasive ability of squamous cell carcinoma cells via tumor-derived IL-1α
    Lining Xie
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Dermatol Sci 61:45-50. 2011
    ..However, the mechanism governing CTSK expression in epidermal tumors remains unclear...
  5. doi request reprint CD10 expressed by fibroblasts and melanoma cells degrades endothelin-1 secreted by human keratinocytes
    Lining Xie
    Department of Dermatology, Kyushu University, 3 1 1 Maidashi Higashiku, Fukuoka 812 8582, Japan
    Eur J Dermatol 21:505-9. 2011
    ..These findings may lead to better understanding of skin homeostasis and of the malignant potential of melanoma...
  6. doi request reprint CD10-bearing fibroblasts may inhibit skin inflammation by down-modulating substance P
    Lining Xie
    Department of Dermatology, Kyushu University, Higashiku, Fukuoka, Japan
    Arch Dermatol Res 303:49-55. 2011
    ..In conclusion, fibroblastic CD10 expression may down-regulate skin inflammation by degrading SP or reducing its level in the dermal microenvironment...
  7. doi request reprint The prognostic value of a reverse transcriptase-PCR assay of sentinel lymph node biopsy for patients with cutaneous melanoma: a single-center analysis in Japan
    Takamichi Ito
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Melanoma Res 22:38-44. 2012
    ..013). SLNB and multimarker RT-PCR analysis are useful for predicting the prognosis of patients with melanoma...
  8. doi request reprint Expression of CD10 predicts tumor progression and unfavorable prognosis in malignant melanoma
    Junna Oba
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Acad Dermatol 65:1152-60. 2011
    ..CD10 expression in malignant melanoma (MM) has been reported to increase according to tumor progression and metastasis; however, its association with patient outcome has not been clarified...
  9. doi request reprint Levels of the EMT-related protein Snail/Slug are not correlated with p53/p63 in cutaneous squamous cell carcinoma
    Hongxiang Chen
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    J Cutan Pathol 40:651-6. 2013
    ..However, to the best of our knowledge, no study has described the immunohistochemical staining of the EMT-related proteins Snail/Slug in skin tumors and the correlation between Snail/Slug and tumor suppressor p53/p63...
  10. doi request reprint Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect
    Gaku Tsuji
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Invest Dermatol 132:59-68. 2012
    ..In conclusion, the engagement of AhR by KCZ exhibits the cytoprotective effect mediated by the Nrf2 redox system, which potently downregulates either cytokine-induced (AhR-independent) or PAH-induced (AhR-dependent) oxidative stress...
  11. doi request reprint Clinicopathologic and prognostic significance of SATB1 in cutaneous malignant melanoma
    Hongxiang Chen
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Dermatol Sci 64:39-44. 2011
    ..However, no data on SATB1 expression and its relationship to tumor progression in cutaneous malignant melanoma (CMM) has yet been reported...
  12. doi request reprint Concordant over-expression of transcription factor Sp1 and vascular endothelial growth factor in extramammary Paget's disease
    Si Yuan Chen
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Dermatol 47:562-6. 2008
    ..But the expression of Sp1 and VEGF has not previously been investigated in extramammary Paget's disease (EMPD)...
  13. doi request reprint Hematopoietic progenitor kinase 1, mitogen-activated protein/extracellular signal-related protein kinase kinase kinase 1, and phosphomitogen-activated protein kinase kinase 4 are overexpressed in extramammary Paget disease
    Yue Qian
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Am J Dermatopathol 33:681-6. 2011
    ..Meanwhile, the expression of TAK1 was basically low and no significantly different between EMPD and normal controls. In conclusion, these results indicate that JNK pathway may play a role in the pathogenesis of EMPD...
  14. doi request reprint An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway
    Gaku Tsuji
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Dermatol Sci 62:42-9. 2011
    ..Although BaP has been shown to exert its biological effects via the aryl hydrocarbon receptor (AhR) signaling pathway, the mechanism of its inflammatory effects on skin remains unanswered...
  15. ncbi request reprint Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous angiosarcoma and pyogenic granuloma
    Si Yuan Chen
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Cutan Pathol 35:722-30. 2008
    ....
  16. doi request reprint CD10-bearing fibroblast inhibits matrigel invasive potency of interleukin-1α-producing squamous cell carcinoma by diminishing substance P levels in the tumor microenvironment
    Lining Xie
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Sci 101:2570-8. 2010
    ..In conclusion, the CD10-bearing Fb generated by SCC-derived IL-1 inhibited the invasive capacity of SCC by diminishing the microenvironmental concentration of substance P...
  17. doi request reprint Expression of S100 protein family members in normal skin and sweat gland tumors
    Li Zhu
    Department of Dermatology, Kyushu University, Fukuoka, Japan Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    J Dermatol Sci 70:211-9. 2013
    ..Despite our growing knowledge regarding the biology of S100 family proteins in cancers and internal diseases, limited data are available with their distribution in normal skin and in sweat gland tumors...
  18. ncbi request reprint Expression of the p38 MAPK, NF-kappaB and cyclin D1 in extramammary Paget's disease
    Nengxing Lin
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashiku, Fukuoka 812 8582, Japan
    J Dermatol Sci 45:187-92. 2007
    ..However, the role of this signal transduction pathway in extramammary Paget's disease (EMPD) remains unknown...
  19. pmc Cutaneous sarcoidosis clinically mimicking necrobiosis lipoidica in a patient with systemic sarcoidosis
    Takahito Chiba
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Dermatol 24:74-6. 2012
    ..We discuss the novel association between sarcoidosis and other granulomatous diseases...
  20. ncbi request reprint Arginine metabolism in soft tissue sarcoma
    Xiaofeng Yan
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    J Dermatol Sci 61:211-5. 2011
    ..Whether l-Arg metabolism has detrimental or beneficial influence on the tumor growth depends on local up regulation of the NOS or ARG pathways at the tumor site...
  21. doi request reprint Aberrant expression of tenascin-c and neuronatin in malignant peripheral nerve sheath tumors
    Long Dugu
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashiku, Fukuoka 812 8582, Japan
    Eur J Dermatol 20:580-4. 2010
    ..The aberrant expression of Nnat and Tn-C was a useful marker for distinguishing MPNSTs from benign NFs...
  22. doi request reprint Hair follicle nevus - A dermoscopic approach
    Junna Okada
    Kyushu University Graduate School of Medicine, Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maedashi 3 1 1, Higashi ku, 812 8582 Fukuoka, Japan
    Eur J Dermatol 18:185-7. 2008
    ..Hair follicle nevus is a very rare disease and this is the first report to demonstrate the manifestation of this clinical entity by dermoscopy...
  23. doi request reprint Herpes zoster-associated voiding dysfunction in hematopoietic malignancy patients
    Shinichi Imafuku
    Division of Dermatology and Hematology, Hiroshima Red Cross and Atomic Bomb Survivor s Hospital, and Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
    Int J Dermatol 47:36-9. 2008
    ..Voiding dysfunction is a rare but important complication of lumbo-sacral herpes zoster. Although the symptoms are transient, the clinical impact on immunocompromised patients cannot be overlooked...
  24. doi request reprint Reduction of CC-chemokine ligand 5 by aryl hydrocarbon receptor ligands
    Saori Morino-Koga
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Fukuoka 812 8582, Japan
    J Dermatol Sci 72:9-15. 2013
    ..Despite numerous investigations targeting AhR ligands, the precise physiological role of AhR remains unknown...
  25. ncbi request reprint The scybala (fecal pellets) of Sacroptes scabiei var. hominis are obviously stained with chlorazol black E
    Takeshi Uenotsuchi
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Dermatol 31:511-2. 2004
  26. doi request reprint Subcutaneous calcification of the lower legs in a patient with mixed connective tissue disease
    Kazuhiko Yamamura
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Dermatol 38:791-3. 2011
    ..On the basis of these findings, we diagnosed skin ulcer due to subcutaneous dystrophic calcification associated with MCTD. The ulcer was gradually reduced in size and epithelialized by treatment with local debridement and antibiotics...