Ken Shirabe

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. pmc Neither MICA Nor DEPDC5 Genetic Polymorphisms Correlate with Hepatocellular Carcinoma Recurrence following Hepatectomy
    Takashi Motomura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    HPB Surg 2012:185496. 2012
  2. doi request reprint Hepatic aflatoxin B1-DNA adducts and TP53 mutations in patients with hepatocellular carcinoma despite low exposure to aflatoxin B1 in southern Japan
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Liver Int 31:1366-72. 2011
  3. doi request reprint Tumor-infiltrating lymphocytes and hepatocellular carcinoma: pathology and clinical management
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Int J Clin Oncol 15:552-8. 2010
  4. ncbi request reprint Prognostic factors in node-negative intrahepatic cholangiocarcinoma with special reference to angiogenesis
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Am J Surg 187:538-42. 2004
  5. doi request reprint Clinicopathological prognostic factors after hepatectomy for patients with mass-forming type intrahepatic cholangiocarcinoma: relevance of the lymphatic invasion index
    Ken Shirabe
    Department of Surgery and Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 17:1816-22. 2010
  6. doi request reprint Risk factors for massive bleeding during major hepatectomy
    Ken Shirabe
    Department of Hepatogastroenterological Surgery, Aso Iizuka Hospital, Iizuka, 820 8505, Japan
    World J Surg 34:1555-62. 2010
  7. doi request reprint Prognostic importance of the gross classification of hepatocellular carcinoma in living donor-related liver transplantation
    K Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Br J Surg 98:261-7. 2011
  8. doi request reprint Early outcome following hepatic resection in patients older than 80 years of age
    Ken Shirabe
    Department of Hepatogastroenterological Surgery, Aso Iizuka Hospital, Iizuka City, 820 8505, Japan
    World J Surg 33:1927-32. 2009
  9. doi request reprint Improvement of long-term outcomes in hepatitis C virus antibody-positive patients with hepatocellular carcinoma after hepatectomy in the modern era
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    World J Surg 35:1072-84. 2011
  10. doi request reprint Comparative evaluation of expanded criteria for patients with hepatocellular carcinoma beyond the Milan criteria undergoing living-related donor liver transplantation
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Clin Transplant 25:E491-8. 2011

Detail Information

Publications129 found, 100 shown here

  1. pmc Neither MICA Nor DEPDC5 Genetic Polymorphisms Correlate with Hepatocellular Carcinoma Recurrence following Hepatectomy
    Takashi Motomura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    HPB Surg 2012:185496. 2012
    ..Conclusions. Neither MICA nor DEPDC5 genetic polymorphism correlates with HCC recurrence following hepatectomy. DEPDC5 minor genotype data suggest a high susceptibility for HCC development in livers, even those with low fibrosis stages...
  2. doi request reprint Hepatic aflatoxin B1-DNA adducts and TP53 mutations in patients with hepatocellular carcinoma despite low exposure to aflatoxin B1 in southern Japan
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Liver Int 31:1366-72. 2011
    ..Mutations in codon 249, exon 7 are a hallmark of AFB1 exposure. Therefore, to clarify the role of AFB1 in hepatocarcinogenesis, we examined AFB1-DNA in liver tissue and sequenced TP53 in Japanese patients with HCC...
  3. doi request reprint Tumor-infiltrating lymphocytes and hepatocellular carcinoma: pathology and clinical management
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Int J Clin Oncol 15:552-8. 2010
    ..The aim of this review is to introduce recent pathological findings for TILs in HCC and to evaluate new therapeutic strategies in this field...
  4. ncbi request reprint Prognostic factors in node-negative intrahepatic cholangiocarcinoma with special reference to angiogenesis
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Am J Surg 187:538-42. 2004
    ..The aim of this study was to clarify prognostic factors and recurrence patterns in patients with node-negative intrahepatic cholangiocarcinoma (IHCC)...
  5. doi request reprint Clinicopathological prognostic factors after hepatectomy for patients with mass-forming type intrahepatic cholangiocarcinoma: relevance of the lymphatic invasion index
    Ken Shirabe
    Department of Surgery and Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 17:1816-22. 2010
    ..The present study was conducted to clarify the pathological factors in patients who underwent surgery for mass-forming type intrahepatic cholangiocarcinoma (IHC)...
  6. doi request reprint Risk factors for massive bleeding during major hepatectomy
    Ken Shirabe
    Department of Hepatogastroenterological Surgery, Aso Iizuka Hospital, Iizuka, 820 8505, Japan
    World J Surg 34:1555-62. 2010
    ..Massive bleeding during hepatectomy is a risk for mortality and morbidity. We examined the risk factors for massive bleeding and their correlations with outcomes...
  7. doi request reprint Prognostic importance of the gross classification of hepatocellular carcinoma in living donor-related liver transplantation
    K Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Br J Surg 98:261-7. 2011
    ..The present study investigated whether the gross classification of HCC is also a prognostic factor in living donor-related liver transplantation (LDLT)...
  8. doi request reprint Early outcome following hepatic resection in patients older than 80 years of age
    Ken Shirabe
    Department of Hepatogastroenterological Surgery, Aso Iizuka Hospital, Iizuka City, 820 8505, Japan
    World J Surg 33:1927-32. 2009
    ..We aimed to study the early outcome of patients 80 years of age and older undergoing liver resection and to compare the results with the outcomes of patients younger than 80 years of age...
  9. doi request reprint Improvement of long-term outcomes in hepatitis C virus antibody-positive patients with hepatocellular carcinoma after hepatectomy in the modern era
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    World J Surg 35:1072-84. 2011
    ..The present study was conducted to clarify the causes of recent improvement of outcomes after hepatectomy in patients with hepatitis C (HC)-related hepatocellular carcinoma (HCC)...
  10. doi request reprint Comparative evaluation of expanded criteria for patients with hepatocellular carcinoma beyond the Milan criteria undergoing living-related donor liver transplantation
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Clin Transplant 25:E491-8. 2011
    ....
  11. doi request reprint Beneficial effects of supplementation with branched-chain amino acids on postoperative bacteremia in living donor liver transplant recipients
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Liver Transpl 17:1073-80. 2011
    ..Nevertheless, this is a preliminary report, and further studies, such as randomized, prospective studies, are necessary to clarify the beneficial effects of BCAA supplementation on postoperative bacteremia after liver transplantation...
  12. ncbi request reprint Prognostic importance of the gross classification of hepatocellular carcinoma in living donor-related liver transplantation
    K Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Br J Surg 98:261-7. 2011
    ..The present study investigated whether the gross classification of HCC is also a prognostic factor in living donor-related liver transplantation (LDLT)...
  13. doi request reprint Role of tumor-associated macrophages in the progression of hepatocellular carcinoma
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Surg Today 42:1-7. 2012
    ..This review discusses the roles of TAM in HCC progression and the possibility of new therapies targeting TAMs...
  14. pmc Prognosis of hepatocellular carcinoma accompanied by microscopic portal vein invasion
    Ken Shirabe
    Department of Hepatogastroenterological Surgery, Aso Iizuka Hospital, Iizuka 820 8505, Japan
    World J Gastroenterol 15:2632-7. 2009
    ..To investigate the prognostic factors in patients with hepatocellular carcinoma (HCC) accompanied by microscopic portal vein invasion (PVI)...
  15. doi request reprint Prognostic factors affecting survival at recurrence of hepatocellular carcinoma after living-donor liver transplantation: with special reference to neutrophil/lymphocyte ratio
    Norifumi Harimoto
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplantation 96:1008-12. 2013
    ..In this study, we investigated the relationship between NLR and prognosis of patients with recurrent HCC after LDLT...
  16. doi request reprint The significance of fibroblast growth factor receptor 2 expression in differentiation of hepatocellular carcinoma
    Norifumi Harimoto
    Department of Gastroenterological Surgery, National Kyushu Cancer Center, Fukuoka, Japan
    Oncology 78:361-8. 2010
    ..These data suggest that FGFR2 may be a potentially useful biological marker of tumor invasiveness in HCC as well as a novel molecular target for HCC...
  17. ncbi request reprint cDNA microarray analysis in hepatocyte differentiation in Huh 7 cells
    Yo ichi Yamashita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Cell Transplant 13:793-9. 2004
    ..5-fold. These results indicate that expressions of Oct-3/4 and EGR-1 may be key factors in the induction of hepatocyte differentiation in Huh 7...
  18. doi request reprint Strategic breakthrough in adult ABO-incompatible living donor liver transplantation: preliminary results of consecutive seven cases
    Yuji Soejima
    Department of Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Transplant 27:227-31. 2013
    ..In conclusion, adult ABO-I LDLT results were excellent - comparable or even superior to those of ABO-compatible LDLT. ABO-I adult LDLT has now become a more applicable modality without the need for an appropriate donor...
  19. doi request reprint The causes, risk factors, and outcomes of early relaparotomy after living-donor liver transplantation
    Shohei Yoshiya
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplantation 94:947-52. 2012
    ..Although early relaparotomy of the recipient after living-donor liver transplantation (LDLT) is a significant event, its causes, risk factors, and outcomes are still unclear...
  20. doi request reprint The long-term outcomes of patients with hepatocellular carcinoma after living donor liver transplantation: a comparison of right and left lobe grafts
    Akinobu Taketomi
    Department of Surgery and Science, Graduate School of Medicine, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Surg Today 42:559-64. 2012
    ..However, the long-term outcome of the hepatocellular carcinoma (HCC) patients with LL grafts has not been elucidated. The aim of this study was to analyze the long-term outcomes after LDLT for HCC according to the graft type...
  21. doi request reprint Zero mortality in more than 300 hepatic resections: validity of preoperative volumetric analysis
    Shinji Itoh
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 42:435-40. 2012
    ....
  22. ncbi request reprint Recurrent hepatitis B following recurrence of hepatocellular carcinoma after living donor liver transplantation
    Hideki Ijichi
    Department of Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 104:376-82. 2013
    ..HBV DNA levels increased despite the treatment with anti-HBV agents after HBV recurrence. In hepatitis B surface antigen positive recipients, HBV prophylaxis should be intensified during the treatment of recurrent HCC...
  23. ncbi request reprint A novel intrahepatic arterial chemotherapy after radical resection for advanced hepatocellular carcinoma
    Shinji Tanaka
    Department of Surgery and Science, Graduate School of Medical Sciences Kyushu University, Fukuoka 812 8582, Japan
    Hepatogastroenterology 52:862-5. 2005
    ..The aim of this study was to evaluate the effectiveness of a novel postoperative adjuvant chemotherapy given through the hepatic artery and based on biochemical modulation using cisplatin (CDDP) and 5-fluorouracil (5-FU)...
  24. doi request reprint Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C
    Takasuke Fukuhara
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Gastroenterology 139:1577-85, 1585.e1-3. 2010
    ..We investigated genetic factors of host, liver donor, and virus that might predict sensitivity of patients with recurrent hepatitis C to PEG-IFN/RBV...
  25. ncbi request reprint The newly established human hepatocyte cell line: application for the bioartificial liver
    Norifumi Harimoto
    The Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Hepatol 42:557-64. 2005
    ..Human hepatocyte cell lines are reported to lose many of their biochemical functions in a hybrid artificial liver support system (HALSS). Differentiation therapy is useful to up-regulate liver function...
  26. doi request reprint Preoperative neutrophil-to-lymphocyte ratio is a predictor of survival after hepatectomy for hepatocellular carcinoma: a retrospective analysis
    Yohei Mano
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg 258:301-5. 2013
    ..To clarify the prognostic value of the preoperative blood neutrophil-to-lymphocyte ratio (NLR) in patients undergoing hepatectomy for hepatocellular carcinoma (HCC)...
  27. doi request reprint Liver regeneration and venous collateral formation in the right lobe living-donor remnant: segmental volumetric analysis and three-dimensional visualization
    Hiroto Kayashima
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    Transplantation 95:353-60. 2013
    ..In left lobe (LL) living-donor liver transplantation (LDLT), hepatic venous congestion (HVC) caused by ligation of the middle hepatic vein tributaries is unavoidable in the right lobe (RL) donor remnant...
  28. doi request reprint Two-stage operation for high-risk patients with thoracic esophageal cancer: an old operation revisited
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 18:2613-21. 2011
    ..An esophagectomy followed by reconstruction for esophageal cancer is a highly aggressive operation. The purpose of this study was to justify a two-stage operation for high-risk patients with esophageal cancer...
  29. ncbi request reprint D-MELD as a Predictor of Early Graft Mortality in Adult-to-Adult Living-Donor Liver Transplantation
    Toru Ikegami
    1 Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2 Address correspondence to Toru Ikegami, M D, Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Transplantation 97:457-62. 2014
    ..Our objective was to evaluate the product of donor age and Model for End-stage Liver Disease score (D-MELD) as a predictor of graft survival after LDLT...
  30. ncbi request reprint Rendezvous technique treatment for late-onset biliary leakage after major hepatectomy of a living donor: report of a case
    Koichi Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Fukuoka Igaku Zasshi 104:309-14. 2013
    ..Rendezvous bidirectional drainage effectively treated late-onset bile leakage from the trifurcation of a hepatic bile duct...
  31. doi request reprint Nutrition support and infections associated with hepatic resection and liver transplantation in patients with chronic liver disease
    Toshiro Masuda
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    JPEN J Parenter Enteral Nutr 37:318-26. 2013
    ..Oral nutrition support with BCAAs, synbiotics, and an immune-enhancing diet have a beneficial effect on preventing the perioperative infections associated with hepatic resection or liver transplantation...
  32. doi request reprint Decreased roundabout 1 expression promotes development of intrahepatic cholangiocarcinoma
    Yohei Mano
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 44:2419-26. 2013
    ..Low Robo1 expression was associated with cell proliferation and migration in ICC and was one of the adverse prognostic factors in patients with these tumors. ..
  33. ncbi request reprint The role of MTA1 gene expression in human hepatocellular carcinoma
    Takayuki Hamatsu
    The Second Department of Surgery, Faculty of Medicine, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Oncol Rep 10:599-604. 2003
    ..05). High expression of the MTA1 gene is suggested to be a new prognostic indicator after curative hepatectomy for HCC...
  34. doi request reprint Acoustic radiation force impulse imaging predicts postoperative ascites resulting from curative hepatic resection for hepatocellular carcinoma
    Noboru Harada
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 151:837-43. 2012
    ..This prospective study investigated how well the VTTQ value predicts the development of postoperative complications before curative hepatic resection for hepatocellular carcinoma (HCC)...
  35. ncbi request reprint Efficacy of a larger version of the hybrid artificial liver support system using a polyurethane foam/spheroid packed-bed module in a warm ischemic liver failure pig model for preclinical experiments
    Yo ichi Yamashita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Cell Transplant 12:101-7. 2003
    ..Serum levels of tumor necrosis factor- a were not elevated in either group. In conclusion, the larger version of the PUF-HALSS demonstrated many advantages as a liver support system in warm ischemic liver failure pigs...
  36. doi request reprint De novo hepatocellular carcinoma in a liver graft with sustained hepatitis C virus clearance after living donor liver transplantation
    Kazutoyo Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Liver Transpl 15:1412-6. 2009
    ..To the best of our knowledge, this is the first report of de novo HCC in a liver graft with sustained hepatitis C virus clearance after LT for advanced HCCs and hepatitis C cirrhosis...
  37. doi request reprint One-step reconstruction of the right inferior hepatic veins using auto-venous grafts in living-donor liver transplantation
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 812 8582, Fukuoka, Japan
    Surg Today 43:769-76. 2013
    ..Reconstruction of the right inferior hepatic vein (RIHV) presents a major technical challenge in living donor liver transplantation (LDLT) using right lobe grafts...
  38. pmc Effect of laparoscopic splenectomy in patients with Hepatitis C and cirrhosis carrying IL28B minor genotype
    Takashi Motomura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    BMC Gastroenterol 12:158. 2012
    ..However, the significance of these genetic variants in cirrhotic patients following splenectomy has not been determined...
  39. ncbi request reprint Strategies for successful left-lobe living donor liver transplantation in 250 consecutive adult cases in a single center
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Coll Surg 216:353-62. 2013
    ..Living donor liver transplantation (LDLT) using left-lobe grafts was not generally recognized as feasible due to the problem of graft size...
  40. doi request reprint V5-drainage-preserved right lobe grafts improve graft congestion for living donor liver transplantation
    Takeo Toshima
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplantation 93:929-35. 2012
    ..This study aimed to evaluate the feasibility of our new V5-drainage-preserved RL (VP-RL) graft...
  41. ncbi request reprint Recurrence of intrahepatic cholangiocarcinoma nine years after surgical resection
    Dai Kitagawa
    Department of Surgery and Medical Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hepatogastroenterology 55:1085-8. 2008
    ....
  42. doi request reprint Predictors of microscopic portal vein invasion by hepatocellular carcinoma: measurement of portal perfusion defect area ratio
    Ken Shirabe
    Department of Hepatogastroenterological Surgery, Aso Iizuka Hospital, Iizuka City, Honshu, Japan
    J Gastroenterol Hepatol 24:1431-6. 2009
    ..Microscopic portal vein invasion (PVI) by cancer cells is a poor prognostic factor after hepatic resection for hepatocellular carcinoma (HCC). The aim of this study is to predict PVI preoperatively in patients with HCC...
  43. doi request reprint De novo autoimmune hepatitis subsequent to switching from type 2b to type 2a alpha-pegylated interferon treatment for recurrent hepatitis C after liver transplantation: report of a case
    Kazuki Takeishi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:1016-9. 2011
    ..He was treated with steroid pulse treatment, followed by high-level immunosuppression maintenance, but eventually died of Pneumocystis pneumonitis 4 months after the diagnosis of de novo AIH...
  44. ncbi request reprint Application of splenectomy to decompress portal pressure in left lobe living donor liver transplantation
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Fukuoka Igaku Zasshi 104:282-9. 2013
    ..0.7 +/- 0.4 L/day, p = 0.01) than Group-NS. The cumulative 5-year graft survival rate was 86.8% in Group-S and 76.2% in Group-NS (p = 0.03). In conclusion, splenectomy had beneficial impacts on graft outcomes in left-lobe LDLT...
  45. ncbi request reprint Obstructing spontaneous major shunt vessels is mandatory to keep adequate portal inflow in living-donor liver transplantation
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplantation 95:1270-7. 2013
    ..It has not been addressed whether the major spontaneous portosystemic shunt vessels should be ligated in living-donor liver transplantation (LDLT)...
  46. doi request reprint Neutrophil-lymphocyte ratio reflects hepatocellular carcinoma recurrence after liver transplantation via inflammatory microenvironment
    Takashi Motomura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Hepatol 58:58-64. 2013
    ..Preoperative neutrophil-lymphocyte ratio (NLR) is a predictor of patient prognosis, but its mechanism has never been clarified...
  47. pmc Factors linked to longterm survival of patients with hepatocellular carcinoma accompanied by tumour thrombus in the major portal vein after surgical resection
    Rumi Matono
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    HPB (Oxford) 14:247-53. 2012
    ..The aim of this study was to clarify the factors linked to survival of >5 years after hepatectomy in HCC patients with MPVTT...
  48. doi request reprint Expanding the applications of microvascular surgical techniques to digestive surgeries: a technical review
    Hideaki Uchiyama
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    Surg Today 42:111-20. 2012
    ..We herein provide a technical review of the application of microvascular surgical techniques for various digestive surgeries...
  49. doi request reprint Risk factors that increase mortality after living donor liver transplantation
    Tomoharu Yoshizumi
    Department of Surgery and Multidisciplinary Treatment, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplantation 93:93-8. 2012
    ..No studies have been performed on the role of gender in the field of living donor liver transplantation. This report investigates the effect of gender mismatch on the outcome of living donor liver transplantation...
  50. doi request reprint Significance of DNA polymerase delta catalytic subunit p125 induced by mutant p53 in the invasive potential of human hepatocellular carcinoma
    Kensaku Sanefuji
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Oncology 79:229-37. 2010
    ..To clarify the role of DNA polymerase delta in tumor progression, we examined the expression of its main catalytic subunit p125 encoded by POLD1 in hepatocellular carcinoma (HCC) and human HCC cell lines...
  51. doi request reprint Predictors of extrahepatic recurrence after curative hepatectomy for hepatocellular carcinoma
    Akinobu Taketomi
    Department of Surgery and Science, Graduate School of Medicine, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 17:2740-6. 2010
    ..The aim of this study was to elucidate the predictors of extrahepatic hepatocellular carcinoma (HCC) recurrence after hepatectomy...
  52. ncbi request reprint Clinical usefulness of biliary scope for Pringle's maneuver in laparoscopic hepatectomy
    Shin ichiro Maehara
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Coll Surg 205:816-8. 2007
  53. doi request reprint Minimal hilar dissection prevents biliary anastomotic stricture after living donor liver transplantation
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplantation 92:1147-51. 2011
    ..The aim of this study is to investigate whether the Min-HD technique could prevent biliary anastomotic stricture (BAS) after LDLT with duct-to-duct biliary reconstruction...
  54. doi request reprint Improved results of a surgical resection for the recurrence of hepatocellular carcinoma after living donor liver transplantation
    Akinobu Taketomi
    Department of Surgery and Science, Graduate School of Medicine, Kyushu University, Higashi ku, Fukuoka, Japan
    Ann Surg Oncol 17:2283-9. 2010
    ..This study was designed to analyze the clinical outcomes of the recurrence of hepatocellular carcinoma (HCC) after living donor liver transplantation (LDLT) and to evaluate the efficacy of a surgical resection in treating such a recurrence...
  55. ncbi request reprint Intratumoral neoadjuvant immunotherapy using IL-12 and dendritic cells is an effective strategy to control recurrence of murine hepatocellular carcinoma in immunosuppressed mice
    Hiroto Kayashima
    Department of Surgery and Science, Kyushu University, Fukuoka, Japan
    J Immunol 185:698-708. 2010
    ....
  56. ncbi request reprint Prognosis of early hepatocellular carcinoma after hepatic resection
    Takashi Maeda
    Department of Surgery and Science, Graduate School of Medical Sciences Kyushu University, Fukuoka, Japan
    Hepatogastroenterology 55:1428-32. 2008
    ..Clinicopathologic characteristics and postoperative prognosis of early hepatocellular carcinoma (eHCC) have not been clarified...
  57. ncbi request reprint Surgical radiofrequency ablation for treatment of hepatocellular carcinoma: an endoscopic or open approach
    Shinji Tanaka
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hepatogastroenterology 56:1169-73. 2009
    ..Endoscopic RFA is a feasible and reliable therapy for unresectable primary HCCs in the patients with cirrhosis...
  58. ncbi request reprint Role of growth factor receptor bound protein 7 in hepatocellular carcinoma
    Shinji Itoh
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Mol Cancer Res 5:667-73. 2007
    ..Grb7 expression can modulate the invasive phenotype of HCC. Grb7 plays an important role in HCC progression and is strongly associated with expression of FAK. Grb7 could be a therapeutic target in HCC...
  59. doi request reprint Third or more repeat hepatectomy for recurrent hepatocellular carcinoma
    Yo ichi Yamashita
    Department of Surgery, Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital, Hiroshima, Japan Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Electronic address
    Surgery 154:1038-45. 2013
    ..The role of repeat hepatectomy for recurrent HCC, especially in cases with third or more repeat hepatectomy, is controversial...
  60. ncbi request reprint Clinical significance of histone deacetylase 1 expression in patients with hepatocellular carcinoma
    Tatsuya Rikimaru
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Oncology 72:69-74. 2007
    ..This study was designed to clarify the role of HDAC1 expression in hepatocellular carcinoma (HCC)...
  61. ncbi request reprint Role of tissue trace elements in liver cancers and non-cancerous liver parenchyma
    Takashi Maeda
    Department of Surgery and Science, Graduate School of Medical Sciences Kyushu University, Fukuoka, Japan
    Hepatogastroenterology 52:187-90. 2005
    ..The aim of this study is to analyze the characteristics of trace elements in liver cancers and non-cancerous liver and to discuss their role in hepatic fibrosis, hepatocarcinogenesis and progression of HCC...
  62. ncbi request reprint Trends in morbidity and mortality after hepatic resection for hepatocellular carcinoma: an institute's experience with 625 patients
    Akinobu Taketomi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Coll Surg 204:580-7. 2007
    ..Despite recent developments in surgery and patient management during the perioperative period, critical complications still developed in a few patients who had hepatic resection for hepatocellular carcinoma (HCC)...
  63. ncbi request reprint Laparoscopic distal pancreatectomy preserving the spleen and splenic vessels for benign and low-grade malignant pancreatic neoplasm
    Tetsuo Ikeda
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 104:54-63. 2013
    ..However, there are few reports regarding the details of the procedure for LSPDP, and its safety remains unclear. This study aimed to evaluate the feasibility and safety of LSPDP...
  64. ncbi request reprint [Total laparoscopic splenectomy for a patient with multiple surgeries including living donor liver transplantation]
    Hiroko Yano
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
    Fukuoka Igaku Zasshi 104:64-7. 2013
    ..The surgery was completed as planned preoperatively under good surgical field...
  65. ncbi request reprint Surgical management of hepatocellular carcinoma in Child-Pugh class B cirrhotic patients: hepatic resection and/or microwave coagulation therapy versus living donor liver transplantation
    Noboru Harada
    Department of Surgery and Medical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Transplant 17:11-20. 2012
    ..The aim of this study was to compare the results of hepatic resection plus microwave coagulation therapy (MCT) versus living donor liver transplantation (LDLT) for HCC in cirrhotic patients with Child-Pugh class B...
  66. doi request reprint Late recurrence after resection of mass-forming intrahepatic cholangiocarcinoma: report of a case
    Naoko Iwahashi Kondo
    Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 8128582, Japan
    Surg Today 42:1210-4. 2012
    ..Long-term follow-up for more than 5 years is recommended because the present case shows that late recurrence of intrahepatic cholangiocarcinoma occurs even 5 years after resection...
  67. doi request reprint Etiologies, risk factors, and outcomes of bacterial pneumonia after living donor liver transplantation
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Liver Transpl 18:1060-8. 2012
    ..Delayed-onset bacterial pneumonia is a serious type of bacterial infection after LDLT and is frequently associated with graft dysfunction. The multidrug resistance of S. maltophilia is an issue that needs to be addressed...
  68. ncbi request reprint Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma
    Shinji Tanaka
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hepatology 37:1122-9. 2003
    ..Our findings suggest that WISP1v-mediated signaling is involved in the generation of invasive cellular properties and leads to progression of cholangiocarcinoma...
  69. doi request reprint Diacylglycerol kinase alpha enhances hepatocellular carcinoma progression by activation of Ras-Raf-MEK-ERK pathway
    Kazuki Takeishi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Hepatol 57:77-83. 2012
    ..Diacylglycerol kinases (DGKs) were recently recognized as key regulators in cell signaling pathways. We investigated whether DGKα is involved in human hepatocellular carcinoma (HCC) progression...
  70. doi request reprint The impact of renal replacement therapy before or after living donor liver transplantation
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Transplant 26:143-8. 2012
    ..The impact of renal replacement therapy (RRT) in living donor liver transplantation (LDLT) has not yet been investigated...
  71. ncbi request reprint The role of heat shock protein 27 expression in hepatocellular carcinoma in Japan: special reference to the difference between hepatitis B and C
    Norifumi Harimoto
    Department of Surgery, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Liver Int 24:316-21. 2004
    ..A recent report showed that heat shock protein (HSP)-27 expression was related to histological grade and survival of patients with hepatocellular carcinoma (HCC)...
  72. ncbi request reprint Preoperative hyaluronic acid measurement to assess the hepatic functional reserve
    Taketoshi Suehiro
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hepatogastroenterology 51:1776-9. 2004
    ..Its half-life time is 2-5 min and HA might be a sensitive liver function marker. We obtained data from 44 patients with liver tumor undergoing liver resection...
  73. doi request reprint Extra-anatomical hepatic artery reconstruction in living donor liver transplantation: can this procedure save hepatic grafts?
    Hideaki Uchiyama
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Liver Transpl 16:1054-61. 2010
    ..These procedures can save hepatic grafts, even when recipient HAs cannot be used as inflow arteries...
  74. ncbi request reprint The predictors of microvascular invasion in candidates for liver transplantation with hepatocellular carcinoma-with special reference to the serum levels of des-gamma-carboxy prothrombin
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Surg Oncol 95:235-40. 2007
    ..A tumor biopsy and a preoperative measurement of DCP could improve the selection of patients with HCC for OLT. Our scoring system for mvi provides us a precise prediction of the presence of mvi...
  75. ncbi request reprint [Extracorporeal hepatic resection for advanced liver cancer]
    Keishi Sugimachi
    Dept of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Gan To Kagaku Ryoho 37:399-401. 2010
    ..In this issue, we give an outline of the indication, procedures, and the problems of EHR...
  76. doi request reprint MR prediction of liver fibrosis using a liver-specific contrast agent: Superparamagnetic iron oxide versus Gd-EOB-DTPA
    Akihiro Nishie
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    J Magn Reson Imaging 36:664-71. 2012
    ..To examine whether the uptake of a liver-specific contrast agent in the liver parenchyma was correlated with the degree of liver fibrosis...
  77. doi request reprint Different incidence of synchronous liver metastasis between proximal and distal colon cancer
    Daisuke Yoshida
    Department of Surgery, Fukuoka Teishin Hospital, 2 6 11 Yakuin, Chuo Ku, Fukuoka, 810 8798, Japan
    Surg Today 42:426-30. 2012
    ..The aim of this study was to evaluate the differences in the features of liver metastasis between proximal and distal colon cancer...
  78. ncbi request reprint Role of expression of focal adhesion kinase in progression of hepatocellular carcinoma
    Shinji Itoh
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Cancer Res 10:2812-7. 2004
    ..The aim of this study was to investigate whether focal adhesion kinase (FAK) is involved in the progression of human HCC...
  79. doi request reprint Total resection of the right hepatic vein drainage area with the aid of three-dimensional computed tomography
    Akinobu Taketomi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Surg Today 42:46-51. 2012
    ..We analyzed the feasibility and safety of our preliminary surgical approach for total hepatic resection of the right hepatic vein drainage area (THR-RHV) with the aid of three-dimensional computed tomography (3D-CT) guidance...
  80. doi request reprint Roles of vascular endothelial growth factor and endothelial nitric oxide synthase during revascularization and regeneration after partial hepatectomy in a rat model
    Daisuke Yoshida
    Department of Disaster and Emergency Medicine, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:1622-9. 2011
    ..This study aimed to determine the roles of NO derived from endothelial nitric oxide synthase (eNOS) and VEGF in sinusoidal endothelial cell (SEC) proliferation during liver regeneration...
  81. ncbi request reprint Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells
    Yo ichi Yamashita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Cancer 103:572-6. 2003
    ..TSA upregulated the ammonia removal rate and the albumin synthesis rate of HepG2 and Huh-7. Our results indicate that TSA can induce cell-cycle arrest/apoptosis and hepatocyte differentiation in human liver cancer cell lines...
  82. ncbi request reprint Gemcitabine combined with 5-fluorouracil and cisplatin (GFP) in patients with advanced biliary tree cancers: a pilot study
    Yo ichi Yamashita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 26:771-5. 2006
    ..To date, no standard chemotherapy regimens have been established. A pilot study to evaluate gemcitabine/5-Fluorouracil(5-FU)/cisplatin(CDDP) (GFP) chemotherapy in patients with advanced biliary tree cancers was performed...
  83. ncbi request reprint Surgical outcome of patients with hepatocellular carcinoma originating in the caudate lobe
    Shinji Tanaka
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Am J Surg 190:451-5. 2005
    ..Hepatocellular carcinoma (HCC) originating in the caudate lobe is rare, and the treatment for this type of carcinoma is difficult because of its unique anatomic location...
  84. doi request reprint Prognostic significance of preoperative imaging in recipients of living donor liver transplantation for hepatocellular carcinoma
    Keishi Sugimachi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Transplantation 91:570-4. 2011
    ..This study aimed to evaluate the preoperative detectability of HCC and clarify the role of preoperative assessment on prognosis after living donor liver transplantation (LDLT)...
  85. doi request reprint Living donor liver transplantation in patients older than 60 years
    Tomoharu Yoshizumi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplantation 90:433-7. 2010
    ..Living donor liver transplantation (LDLT) has been performed in adult patients. However, there are a few reports on how recipient age affects the outcome of LDLT. This study assessed LDLT outcome in patients aged 60 years or older...
  86. doi request reprint New method for assessing liver fibrosis based on acoustic radiation force impulse: a special reference to the difference between right and left liver
    Takeo Toshima
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol 46:705-11. 2011
    ..In this study, we examined the diagnostic performance of ARFI imaging in 103 patients, focusing on the difference in VTTQ values between the right and left liver lobes...
  87. ncbi request reprint Use of recipient's left hepatic artery for artery reconstruction in right lobe living donor liver transplantation with duct-to-duct anastomosis
    Hideaki Uchiyama
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplantation 89:1016-21. 2010
    ..This study retrospectively investigated whether the selection of left or right HA for HA reconstruction affects the outcomes of right lobe LDLT (RL-LDLT)...
  88. doi request reprint Bacterial sepsis after living donor liver transplantation: the impact of early enteral nutrition
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Coll Surg 214:288-95. 2012
    ..Bacterial sepsis is a significant problem that must be addressed after living donor liver transplantation (LDLT)...
  89. doi request reprint Soft coagulation, polyglycolic acid felt, and fibrin glue for prevention of pancreatic fistula after distal pancreatectomy
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:1224-7. 2011
    ..To evaluate the effectiveness of using soft coagulation followed by the application of polyglycolic acid (PGA) felt and fibrin glue to prevent pancreatic fistula (PF) after distal pancreatectomy (DP)...
  90. doi request reprint Hepatocellular carcinoma with marginal superparamagnetic iron oxide uptake on T2*-weighted magnetic resonance imaging: histopathologic correlation
    Kousei Ishigami
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Eur J Radiol 80:e293-8. 2011
    ..To evaluate the characteristics of hepatocellular carcinomas (HCCs) with marginal superparamagnetic iron oxide (SPIO) uptake on T2*-weighted MRI...
  91. ncbi request reprint Analysis of the prognostic factors for liver metastasis of gastric cancer after hepatic resection: a multi-institutional study of the indications for resection
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Science, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8581, Japan
    Hepatogastroenterology 50:1560-3. 2003
    ..The number of reports of hepatic resection for metastatic gastric cancer is very small. The outcome and indications of hepatic resection for metastatic gastric cancer remains unknown...
  92. ncbi request reprint Significance of the relationship between irregular regeneration and two hepatocarcinogenic pathways: "de novo" and so-called "dysplastic nodule-hepatocellular carcinoma" sequence
    Kenichi Taguchi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Surg Oncol 92:100-3. 2005
    ..quot;..
  93. doi request reprint Living donor hepatectomies with procedures to prevent biliary complications
    Akinobu Taketomi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Coll Surg 211:456-64. 2010
    ..Biliary complications in donor hepatectomies are still common, and occur in approximately 5% of the procedures...
  94. doi request reprint Histologic classification of microscopic portal venous invasion to predict prognosis in hepatocellular carcinoma
    Nobuhiro Fujita
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 42:1531-8. 2011
    ..0259). We proposed a new definition for classifying microscopic portal venous invasion and documented the necessity of definite histologic evaluation of it...
  95. doi request reprint Outcomes of hepatic resection for huge hepatocellular carcinoma (≥ 10 cm in diameter)
    Yo ichi Yamashita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    J Surg Oncol 104:292-8. 2011
    ..The object of the current study was to review the outcomes of hepatic resection for hepatocellular carcinoma (HCC) ≥ 10 cm...
  96. doi request reprint Evaluation of ERCC1 expression for cisplatin sensitivity in human hepatocellular carcinoma
    Shigeru Ueda
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 18:1204-11. 2011
    ..This study was designed to investigate the correlation between ERCC1 expression and chemosensitivity to cisplatin (CDDP) in patients with hepatocellular carcinoma (HCC)...
  97. doi request reprint Both fibrous capsule formation and extracapsular penetration are powerful predictors of poor survival in human hepatocellular carcinoma: a histological assessment of 365 patients in Japan
    Tomohiro Iguchi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 16:2539-46. 2009
    ..The current aim was to present evidence to develop the fibrous capsule and fc-inf, from the Japanese histological findings for HCC, and to validate their biological significances and predictive power of survival in a large series...
  98. ncbi request reprint Muscle-targeted interleukin-12 gene therapy of orthotopic hepatocellular carcinoma in mice using in vivo electrosonoporation
    Yo ichi Yamashita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Mol Cancer Ther 3:1177-82. 2004
    ..These results show that muscle-targeted mIL-12 gene therapy for orthotopic HCC using in vivo electrosonoporation is very efficient and is thus promising for further clinical trial...
  99. doi request reprint Living donor liver transplantation for end-stage liver disease with severe hepatopulmonary syndrome: report of a case
    Takashi Motomura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:436-40. 2011
    ..She was discharged from hospital on posttransplant day 39 with an SpO(2) of 94% under 3 l/min of O(2), delivered nasally. Despite the severity of the HPS, her postoperative recovery was smooth after the liver transplant...
  100. ncbi request reprint The role of serum interleukin-8 in hepatic resections
    Tomonobu Gion
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 40:543-8. 2010
    ..The aim of this study was to investigate whether the early postoperative serum IL-8 level may potentially be a new indicator of a surgical stress in patients undergoing a hepatic resection...
  101. ncbi request reprint The utility of keratin 903 as a new prognostic marker in mass-forming-type intrahepatic cholangiocarcinoma
    Shin ichi Aishima
    Department of Anatomic Pathology and of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mod Pathol 15:1181-90. 2002
    ..Remarkably, the cytokeratin phenotype of intrahepatic cholangiocarcinoma was correlated with the morphologic appearance of intrahepatic cholangiocarcinoma...