Yoshinao Oda

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint Low-grade fibromyxoid sarcoma versus low-grade myxofibrosarcoma in the extremities and trunk. A comparison of clinicopathological and immunohistochemical features
    Y Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Histopathology 45:29-38. 2004
  2. ncbi request reprint ATP-binding cassette superfamily transporter gene expression in human soft tissue sarcomas
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Int J Cancer 114:854-62. 2005
  3. ncbi request reprint Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas
    Koji Shindo
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    Mol Cancer 12:168. 2013
  4. pmc Dedifferentiated chondrosarcoma of the cervical spine: a case report
    Yoshihiro Matsumoto
    Department of Orthopedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    World J Surg Oncol 11:32. 2013
  5. pmc Myxoid liposarcoma with negative features on bone scan and [18F]-2-fluoro-2-deoxy-D-glucose-positron emission tomography
    Akio Sakamoto
    Department of Orthopaedic Surgery, National Hospital Organization Kokura Medical Center, Kitakyushu, Fukuoka 802 0803, Japan
    World J Surg Oncol 10:214. 2012
  6. pmc Clinical outcome for patients with dedifferentiated chondrosarcoma: a report of 9 cases at a single institute
    Kazuya Yokota
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Orthop Surg Res 7:38. 2012
  7. pmc Chondroblastoma of the distal femur resected through a small fenestra via computed tomography navigation and endoscopy: a case report
    Tsuyoshi Miyazaki
    Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23 3, Eiheiji, Fukui 910 1193, Japan
    J Med Case Rep 7:164. 2013
  8. pmc Nonossifying fibroma presenting as an aneurysmal bone cyst: a case report
    Akio Sakamoto
    Department of Orthopaedic Surgery, National Hospital Organization Kokura Medical Center, Kitakyushu, Fukuoka, Japan
    J Med Case Rep 6:407. 2012
  9. pmc miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor
    Keiichiro Iida
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Maidashi3 1 1, Fukuoka, 812 8582, Japan
    Cancer Cell Int 13:21. 2013
  10. pmc Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features
    Akio Sakamoto
    Department of Orthopedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    World J Surg Oncol 5:88. 2007

Detail Information

Publications140 found, 100 shown here

  1. ncbi request reprint Low-grade fibromyxoid sarcoma versus low-grade myxofibrosarcoma in the extremities and trunk. A comparison of clinicopathological and immunohistochemical features
    Y Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Histopathology 45:29-38. 2004
    ....
  2. ncbi request reprint ATP-binding cassette superfamily transporter gene expression in human soft tissue sarcomas
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Int J Cancer 114:854-62. 2005
    ..In addition, the high levels of both MDR1 and MRP3 mRNA expression in MPNST may help to explain the poor response of this tumor to anticancer-drugs...
  3. ncbi request reprint Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas
    Koji Shindo
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    Mol Cancer 12:168. 2013
    ..Podoplanin (PDPN) is a lymphatic vessel marker (D2-40), and expression of PDPN by stromal CAFs has been reported to be a prognostic indicator in various types of cancer...
  4. pmc Dedifferentiated chondrosarcoma of the cervical spine: a case report
    Yoshihiro Matsumoto
    Department of Orthopedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    World J Surg Oncol 11:32. 2013
    ..However, atypical spindle cells that had proliferated in a fascicular pattern with a collagenous stroma, mimicking fibrosarcoma, were focally observed without a transitional zone, and these features confirmed that the tumor was DDCS...
  5. pmc Myxoid liposarcoma with negative features on bone scan and [18F]-2-fluoro-2-deoxy-D-glucose-positron emission tomography
    Akio Sakamoto
    Department of Orthopaedic Surgery, National Hospital Organization Kokura Medical Center, Kitakyushu, Fukuoka 802 0803, Japan
    World J Surg Oncol 10:214. 2012
    ..However, both methods have a low positive rate with regard to vertebral metastasis arising from myxoid liposarcoma. This is particularly true for bone scans for intramedullary lesions that have no cortical involvement...
  6. pmc Clinical outcome for patients with dedifferentiated chondrosarcoma: a report of 9 cases at a single institute
    Kazuya Yokota
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Orthop Surg Res 7:38. 2012
    ..Dedifferentiated chondrosarcomas consist of two distinguishable components: low-grade chondrosarcoma components and high-grade dedifferentiated components...
  7. pmc Chondroblastoma of the distal femur resected through a small fenestra via computed tomography navigation and endoscopy: a case report
    Tsuyoshi Miyazaki
    Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23 3, Eiheiji, Fukui 910 1193, Japan
    J Med Case Rep 7:164. 2013
    ..In our patient's case, we used a computed tomography-based navigation system with registration technique involving skin marker fiduciaries and endoscopic curettage of the lesion...
  8. pmc Nonossifying fibroma presenting as an aneurysmal bone cyst: a case report
    Akio Sakamoto
    Department of Orthopaedic Surgery, National Hospital Organization Kokura Medical Center, Kitakyushu, Fukuoka, Japan
    J Med Case Rep 6:407. 2012
    ..abstract:..
  9. pmc miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor
    Keiichiro Iida
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Maidashi3 1 1, Fukuoka, 812 8582, Japan
    Cancer Cell Int 13:21. 2013
    ..In this study, we investigated the possible role that miRNAs may play in the development of chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor (EWS)...
  10. pmc Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features
    Akio Sakamoto
    Department of Orthopedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    World J Surg Oncol 5:88. 2007
    ..abstract:..
  11. pmc Dedifferentiated liposarcoma with leukocytosis. A case report of G-CSF-producing soft-tissue tumors, possible association with undifferentiated liposarcoma lineage
    Akio Sakamoto
    Department of Orthopedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    World J Surg Oncol 5:131. 2007
    ..abstract:..
  12. pmc Mutation analysis of the Gadd45 gene at exon 4 in atypical fibroxanthoma
    Akio Sakamoto
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    BMC Dermatol 9:1. 2009
    ..Bax and Gadd45 are p53 effector proteins. Bax is a programmed cell death protein and belongs to the Bcl-2 family. Gadd45 is a multifunctional DNA damage-inducible gene associated with the process of DNA damage...
  13. ncbi request reprint Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Pathol 207:410-21. 2005
    ..In MLS/RCLS, reduction of p14 protein expression and p53 mutation were related to poor prognosis. Accordingly, the p14(ARF)/p53 pathway may contribute to the presence of an RC component and malignant progression in this tumour...
  14. ncbi request reprint CXCR4 and VEGF expression in the primary site and the metastatic site of human osteosarcoma: analysis within a group of patients, all of whom developed lung metastasis
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
    Mod Pathol 19:738-45. 2006
    ..0053). Our results suggested that CXCR4 expression was associated with metastatic progression, and immunohistochemical VEGF expression in the primary site had predictive value for the osteosarcoma patients, who developed lung metastasis...
  15. ncbi request reprint Extrarenal rhabdoid tumors of soft tissue: clinicopathological and molecular genetic review and distinction from other soft-tissue sarcomas with rhabdoid features
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pathol Int 56:287-95. 2006
    ..Detailed clinicopathological and immunohistochemical evaluations are necessary to distinguish MRT of soft tissue from proximal-type ES, because these tumors demonstrated a similar morphology and the same gene alteration...
  16. ncbi request reprint Prognostic implications of the nuclear localization of Y-box-binding protein-1 and CXCR4 expression in ovarian cancer: their correlation with activated Akt, LRP/MVP and P-glycoprotein expression
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Sci 98:1020-6. 2007
    ..These results indicate that YB-1 nuclear expression and CXCR4 expression are important prognostic factors in ovarian carcinoma...
  17. doi request reprint Chemokine receptor CXCR4 expression is correlated with VEGF expression and poor survival in soft-tissue sarcoma
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Cancer 124:1852-9. 2009
    ..Determination of the CXCR4 expression level as a novel marker can provide useful prognostic information for patients and it could be a candidate for molecular targeting therapy in MNRCTs of soft-tissue sarcomas...
  18. ncbi request reprint Pigmented villonodular synovitis with chondroid metaplasia, resembling chondroblastoma of the bone: a report of three cases
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mod Pathol 20:545-51. 2007
    ..The correlation between this lesion and synovial chondromatosis remains uncertain...
  19. doi request reprint Recent advances in the molecular pathology of soft tissue sarcoma: implications for diagnosis, patient prognosis, and molecular target therapy in the future
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Cancer Sci 100:200-8. 2009
    ..In conclusion, further studies are necessary to search for effective and specific molecules for the inhibition of tumor growth in each type of STS, especially in sarcomas without specific translocation...
  20. doi request reprint Different expression profiles of Y-box-binding protein-1 and multidrug resistance-associated proteins between alveolar and embryonal rhabdomyosarcoma
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Cancer Sci 99:726-32. 2008
    ..Apart from ERMS, frequent P-gp expression in ARMS may be independent from YB-1 regulation. However, YB-1 may be a candidate for a molecular target in rhabdomyosarcoma therapy, especially in ERMS...
  21. doi request reprint Infrequent SMARCB1/INI1 gene alteration in epithelioid sarcoma: a useful tool in distinguishing epithelioid sarcoma from malignant rhabdoid tumor
    Kenichi Kohashi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 40:349-55. 2009
    ..Analysis of alterations in the SMARCB1/INI1 gene may thus be a useful diagnostic tool to distinguish proximal-type epithelioid sarcoma from malignant rhabdoid tumor...
  22. ncbi request reprint Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma
    Yukiko Takahashi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mod Pathol 17:660-9. 2004
    ..Alveolar type had a significantly higher both mitotic rate and E2F-1 labeling indices when compared with the embryonal type. The current study is the first report of the correlation of E2F-1 with alveolar rhabdomyosarcoma...
  23. ncbi request reprint Nuclear expression of Y-box-binding protein-1 correlates with P-glycoprotein and topoisomerase II alpha expression, and with poor prognosis in synovial sarcoma
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Pathol 199:251-8. 2003
    ....
  24. ncbi request reprint Dysadherin expression as a significant prognostic factor and as a determinant of histologic features in synovial sarcoma: special reference to its inverse relationship with E-cadherin expression
    Teiyu Izumi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Am J Surg Pathol 31:85-94. 2007
    ..Dysadherin expression is considered to be one of the determinants of histologic subtype in synovial sarcoma. Moreover, dysadherin expression is an excellent and independent prognostic indicator...
  25. doi request reprint Pdcd4 expression in intraductal papillary mucinous neoplasm of the pancreas: its association with tumor progression and proliferation
    Akifumi Hayashi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University 3 1 1 Maidashi, Fukuoka, 812 8582, Japan
    Hum Pathol 41:1507-15. 2010
    ..Therefore, programmed cell death 4 can be an important biomarker for intraductal papillary mucinous neoplasm...
  26. ncbi request reprint Malignant transformation of mature cystic teratoma to squamous cell carcinoma involves altered expression of p53- and p16/Rb-dependent cell cycle regulator proteins
    Atsuko Iwasa
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pathol Int 58:757-64. 2008
    ..The results indicate that alterations in both the p53 and p16-Rb pathways are associated with SCC arising in MCT...
  27. doi request reprint SMARCB1/INI1 protein expression in round cell soft tissue sarcomas associated with chromosomal translocations involving EWS: a special reference to SMARCB1/INI1 negative variant extraskeletal myxoid chondrosarcoma
    Kenichi Kohashi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, Japan
    Am J Surg Pathol 32:1168-74. 2008
    ..The immunohistochemical result of the SMARCB1/INI expression is not an absolute diagnostic criteria for MRT and careful histologic evaluation is required to make a precise diagnosis of MRT...
  28. ncbi request reprint Aberrant expression of CHFR in malignant peripheral nerve sheath tumors
    Chikashi Kobayashi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
    Mod Pathol 19:524-32. 2006
    ..In addition, MPNST with normal karyotype showed a strong (score, =5) expression of CHFR. Our results support the assertion that CHFR functions as an inhibitor of tumor proliferation...
  29. ncbi request reprint DNA hypermethylation status of multiple genes in soft tissue sarcomas
    Ken Ichi Kawaguchi
    Department of Anatomic Pathology, Pathological Sciences, Kyushu University, Fukuoka, Japan
    Mod Pathol 19:106-14. 2006
    ..Furthermore, MGMT methylation may be associated with tumor aggressiveness and the inactivation of MGMT gene...
  30. ncbi request reprint Microsatellite instability and hMLH1 and hMSH2 expression analysis in soft tissue sarcomas
    Ken Ichi Kawaguchi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Oncol Rep 13:241-6. 2005
    ..These findings suggest that the inactivation of MMR gene expression might be the cause of MSI in STS cases...
  31. ncbi request reprint ATP-binding cassette superfamily transporter gene expression in human primary ovarian carcinoma
    Yoshihiro Ohishi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Clin Cancer Res 8:3767-75. 2002
    ....
  32. ncbi request reprint Altered expression of cell cycle regulators in myxofibrosarcoma, with special emphasis on their prognostic implications
    Yoshinao Oda
    Department of Anatomic Pathology, Graduate School of Medical Information Science, Kyushu University, Fukuoka, Japan
    Hum Pathol 34:1035-42. 2003
    ..Our results suggest that reduced expression of p21 could be considered a new parameter to be evaluated, along with classical clinicopathologic prognostic factors, for identifying those at high risk for myxofibrosarcoma...
  33. ncbi request reprint Possible association between tumor-suppressor gene mutations and hMSH2/hMLH1 inactivation in alveolar soft part sarcoma
    Tsuyoshi Saito
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hum Pathol 34:841-9. 2003
    ..Thus, inactivation of hMSH2/hMLH1 of DNA mismatch repair genes seems to have an important role to play in the mutagenesis of the tumor-suppressor genes in ASPS...
  34. ncbi request reprint PTEN and other tumor suppressor gene mutations as secondary genetic alterations in synovial sarcoma
    Tsuyoshi Saito
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Oncol Rep 11:1011-5. 2004
    ..8%), although the mutation status in TSG was not associated with overall survival rate in patients with SS. Secondary genetic alterations in these TSG seem to have a less important prognostic impact on patients with SS...
  35. doi request reprint Reduced expression of SMARCB1/INI1 protein in synovial sarcoma
    Kenichi Kohashi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Mod Pathol 23:981-90. 2010
    ..46). Therefore, it was suggested that there is a post-transcriptional SMARCB1/INI1 regulatory mechanism in the tumor cells of synovial sarcoma...
  36. doi request reprint Coincident expression of beta-catenin and cyclin D1 in endometrial stromal tumors and related high-grade sarcomas
    Shuichi Kurihara
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Mod Pathol 23:225-34. 2010
    ..This finding raises the possibility that cyclin D1 is upregulated by beta-catenin in these high-grade sarcomas previously called high-grade endometrial stromal sarcoma...
  37. ncbi request reprint Prognostic significance of dysadherin expression in epithelioid sarcoma and its diagnostic utility in distinguishing epithelioid sarcoma from malignant rhabdoid tumor
    Teiyu Izumi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mod Pathol 19:820-31. 2006
    ..However, in malignant rhabdoid tumor, cell growth cycle that is regulated by hSNF5/INI1 gene seems to be critical to lethal biological behavior rather than dysadherin...
  38. doi request reprint Sessile serrated adenoma with early neoplastic progression: a clinicopathologic and molecular study
    Kohei Fujita
    Department of Anatomic Pathology, Kyushu University, Fukuoka, Japan
    Am J Surg Pathol 35:295-304. 2011
    ..In addition, our histologic observations suggest a possible close association between SSAN and mucinous adenocarcinoma...
  39. ncbi request reprint Highly aggressive behavior of malignant rhabdoid tumor: a special reference to SMARCB1/INI1 gene alterations using molecular genetic analysis including quantitative real-time PCR
    Kenichi Kohashi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, 812 8582, Japan
    J Cancer Res Clin Oncol 133:817-24. 2007
    ..Moreover, we investigated the status of hyperphosphorylation in RB protein, known as a key cell cycle molecule...
  40. doi request reprint Correlation between beta-catenin widespread nuclear expression and matrix metalloproteinase-7 overexpression in sporadic desmoid tumors
    Hiroshi Matono
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582 Japan
    Hum Pathol 39:1802-8. 2008
    ....
  41. doi request reprint S100P is a novel marker to identify intraductal papillary mucinous neoplasms
    Kohei Nakata
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 41:824-31. 2010
    ..On the other hand, MUC5AC was expressed in only 23 cases of 32 invasive components (P < .01). These data suggest that the S100P antibody may be a useful marker for detecting all types of intraductal papillary mucinous neoplasms...
  42. doi request reprint HER2 and EGFR gene copy number alterations are predominant in high-grade salivary mucoepidermoid carcinoma irrespective of MAML2 fusion status
    Takafumi Nakano
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Department of Otolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Histopathology 63:378-92. 2013
    ..In this study, we aimed to investigate the molecular mechanisms underlying the development of mucoepidermoid carcinoma (MEC)...
  43. doi request reprint Differential ezrin and phosphorylated ezrin expression profiles between pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, and invasive ductal carcinoma of the pancreas
    Yasunori Oda
    Department of Anatomic Pathology, Graduate School of Medical Science, Kyushu University, Maidashi 3 1 1, Fukuoka 812 8582, Japan
    Hum Pathol 44:1487-98. 2013
    ....
  44. doi request reprint Endometrial stromal sarcomas and related high-grade sarcomas: immunohistochemical and molecular genetic study of 31 cases
    Shuichi Kurihara
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, Japan
    Am J Surg Pathol 32:1228-38. 2008
    ..Our data suggest that UES-U shares some molecular genetic and immunohistochemical characteristics with ESS-LG, but UES-P considerably differs from ESS-LG...
  45. ncbi request reprint Cytoplasmic and stromal expression of laminin γ 2 chain correlates with infiltrative invasion in ovarian mucinous neoplasms of gastro-intestinal type
    Emi Okuma
    Department of Anatomic Pathology, Kyushu University Hospital, Fukuoka, Japan
    Oncol Rep 24:1569-76. 2010
    ..The staining pattern of mural nodules was similar to that of infiltrative invasion. The infiltrative invasion of GI-type ovarian mucinous neoplasms may be promoted by cytoplasmic and/or stromal expression of laminin γ 2 chain...
  46. ncbi request reprint Mechanisms of inactivation of the p16INK4a gene in leiomyosarcoma of soft tissue: decreased p16 expression correlates with promoter methylation and poor prognosis
    Ken Ichi Kawaguchi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Pathol 201:487-95. 2003
    ..Furthermore, promoter methylation was more frequent than either homozygous deletion or mutation in this tumour, and promoter methylation was also shown to have a strong association with inactivation of the p16INK4a gene...
  47. doi request reprint Concordance for neuroblastoma in monozygotic twins: case report and review of the literature
    Tatsuro Tajiri
    Department of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Pediatr Surg 45:2312-6. 2010
    ..This study is the first report presenting the possibility of twin-to-twin metastasis in monozygotic twins with neuroblastoma based on an analysis of the clinical features and genetic aberrations...
  48. ncbi request reprint APC mutations in synovial sarcoma
    Tsuyoshi Saito
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Pathol 196:445-9. 2002
    ..All three cases with APC mutations available for follow-up data were long survivors. This study provides the first evidence that APC mutations also occur in the field of sarcoma, especially in synovial sarcoma...
  49. ncbi request reprint Alterations of RB1 gene in embryonal and alveolar rhabdomyosarcoma: special reference to utility of pRB immunoreactivity in differential diagnosis of rhabdomyosarcoma subtype
    Kenichi Kohashi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, Japan
    J Cancer Res Clin Oncol 134:1097-103. 2008
    ..Therefore, there might be a correlation between the tumorigenesis of RMS and RB1 alteration...
  50. doi request reprint Decreased roundabout 1 expression promotes development of intrahepatic cholangiocarcinoma
    Yohei Mano
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 44:2419-26. 2013
    ..Low Robo1 expression was associated with cell proliferation and migration in ICC and was one of the adverse prognostic factors in patients with these tumors. ..
  51. ncbi request reprint Genetic and epigenetic alterations of the PTEN gene in soft tissue sarcomas
    Ken Ichi Kawaguchi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 36:357-63. 2005
    ..Furthermore, although a further detailed analysis of a larger number of cases is still necessary, the present results suggest that PTEN expression may be a useful indicator of cell proliferation in patients with STS...
  52. doi request reprint The risk of lymph node metastasis in mucosal gastric carcinoma: especially for a mixture of differentiated and undifferentiated adenocarcinoma
    Kohei Nakata
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hepatogastroenterology 59:1855-8. 2012
    ..Our aims were to confirm the frequency of lymph node metastasis in such cases and clarify the demarcation in indications for ESD...
  53. doi request reprint Long-term survival after autologous peripheral blood stem cell transplantation in two patients with malignant rhabdoid tumor of the kidney
    Yuhki Koga
    Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pediatr Blood Cancer 52:888-90. 2009
    ..Two patients have been alive without any evidence of disease for 30 and 37 months after diagnosis, respectively, and require no medication. Consolidation with SCT should be further studies for selected patients with high-risk MRTK...
  54. ncbi request reprint Beta-catenin accumulation and gene mutation in exon 3 in dedifferentiated liposarcoma and malignant fibrous histiocytoma
    Akio Sakamoto
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Arch Pathol Lab Med 126:1071-8. 2002
    ..beta-Catenin is an adhesion molecule that also plays a role in the Wnt signaling pathway. Objective.-To analyze beta-catenin mutation and accumulation in a series of liposarcomas and malignant fibrous histiocytomas...
  55. doi request reprint Mitochondrial p32/C1QBP is highly expressed in prostate cancer and is associated with shorter prostate-specific antigen relapse time after radical prostatectomy
    Rie Amamoto
    Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Sci 102:639-47. 2011
    ..These data suggest that p32 is critical for prostate cancer cell proliferation and may be a novel marker of clinical progression in prostate cancer...
  56. doi request reprint Different roles of S100P overexpression in intrahepatic cholangiocarcinoma: carcinogenesis of perihilar type and aggressive behavior of peripheral type
    Shinichi Aishima
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Am J Surg Pathol 35:590-8. 2011
    ..001, P=0.0728, respectively). Our results suggest that S100P-ezrin signaling has different roles of carcinogenesis of perihilar ICC and an aggressive course of peripheral ICC...
  57. doi request reprint Treatment strategy for main duct intraductal papillary mucinous neoplasms of the pancreas based on the assessment of recurrence in the remnant pancreas after resection: a retrospective review
    Koji Tamura
    Departments of Surgery and Oncology Anatomic Pathology Clinical Radiology, and Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg 259:360-8. 2014
    ..To clarify the recurrence pattern after resection of main duct intraductal papillary mucinous neoplasms (MD-IPMNs) using molecular analyses and determine the most adequate treatment strategy...
  58. doi request reprint Insulin-like growth factor II messenger RNA-binding protein-3 is a valuable diagnostic and prognostic marker of intraductal papillary mucinous neoplasm
    Katsuya Morimatsu
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 44:1714-21. 2013
    ..0069). In conclusion, our findings show that IMP3 is a useful diagnostic marker for distinguishing between noncancerous and cancerous lesions and is a valuable prognostic biomarker in IPMN. ..
  59. doi request reprint Tumor-associated macrophage promotes tumor progression via STAT3 signaling in hepatocellular carcinoma
    Yohei Mano
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pathobiology 80:146-54. 2013
    ..Therefore, we examined STAT3 activation, cytokine expression and infiltration of tumor-associated macrophages in resected HCCs as well as the alteration of cell growth and migration by cytokine stimulation in HCC cell lines...
  60. ncbi request reprint E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma
    Tsuyoshi Saito
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Oncogene 23:8629-38. 2004
    ..Thus, E-cadherin downregulation is associated with the loss or absence of glandular epithelial differentiation in certain SS...
  61. ncbi request reprint Death-associated protein kinase (DAP kinase) alteration in soft tissue leiomyosarcoma: Promoter methylation or homozygous deletion is associated with a loss of DAP kinase expression
    Ken Ichi Kawaguchi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hum Pathol 35:1266-71. 2004
    ..Furthermore, although further detailed analyses are necessary, promoter methylation or homozygous deletion status of DAP kinase may present a major alternative mechanism of a loss of or decrease in DAP kinase expression...
  62. doi request reprint Abnormalities of the Wnt/β-catenin signalling pathway induce tumour progression in sporadic desmoid tumours: correlation between β-catenin widespread nuclear expression and VEGF overexpression
    Hiroshi Matono
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Histopathology 59:368-75. 2011
    ..To analyse the correlation between β-catenin and vascular endothelial growth factor (VEGF) in sporadic desmoid tumours...
  63. ncbi request reprint Involvement of P-glycoprotein and MRP1 in resistance to cyclic tetrapeptide subfamily of histone deacetylase inhibitors in the drug-resistant osteosarcoma and Ewing's sarcoma cells
    Takamitsu Okada
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Cancer 118:90-7. 2006
    ..Because HDACIs are potent and promising antitumor drugs and seem to be close to clinical use, it is necessary to pay attention to the resistance mechanisms against HDACIs...
  64. doi request reprint Glypican 3 expression in tumors with loss of SMARCB1/INI1 protein expression
    Kenichi Kohashi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Hum Pathol 44:526-33. 2013
    ..Therefore, evaluation of GPC3 immunoexpression may be a useful diagnostic tool to distinguish ES from MRT, especially extrarenal MRT. It was suggested that MRTs with GPC3 overexpression may become a new target of GPC3 immunotherapy...
  65. doi request reprint Phosphorylation of signal transducer and activator of transcription 3 in soft tissue leiomyosarcoma is associated with a better prognosis
    Nokitaka Setsu
    Department of Anatomic Pathology, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Int J Cancer 132:109-15. 2013
    ..STAT3 might not contribute to the progression of soft tissue LMS, and the phosphorylation status of STAT3 has the potential to be a favorable prognostic marker of LMS...
  66. doi request reprint Liver-intestine cadherin expression is associated with intestinal differentiation and carcinogenesis in intraductal papillary mucinous neoplasm
    Katsuya Morimatsu
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pathobiology 79:107-14. 2012
    ..Like mucin 2, oligomeric mucus/gel forming (MUC2) and caudal-related homeobox 2 (CDX2), liver-intestine cadherin (LI cadherin) is an intestine-specific marker. We aimed to investigate the roles of LI cadherin expression in IPMN...
  67. doi request reprint The Akt/mammalian target of rapamycin pathway is activated and associated with adverse prognosis in soft tissue leiomyosarcomas
    Nokitaka Setsu
    Department of Anatomic Pathology, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Cancer 118:1637-48. 2012
    ..Here the authors investigated the significance of activation of the Akt/mTOR pathway in soft tissue leiomyosarcomas...
  68. doi request reprint Expression of activation-induced cytidine deaminase in ulcerative colitis-associated carcinogenesis
    Masaki Gushima
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Histopathology 59:460-9. 2011
    ..The aim of this study was to investigate the expression of AID and its association with p53 mutation in ulcerative colitis (UC)-associated carcinogenesis...
  69. ncbi request reprint Alterations of the RB1 gene in dedifferentiated liposarcoma
    Tomonari Takahira
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mod Pathol 18:1461-70. 2005
    ..These results suggest that retinoblastoma protein has a major role to play in dedifferentiation and that a 'two-hit' mechanism is involved in the altered retinoblastoma protein expression in dedifferentiated liposarcoma...
  70. doi request reprint Invasive carcinoma derived from intestinal-type intraductal papillary mucinous neoplasm is associated with minimal invasion, colloid carcinoma, and less invasive behavior, leading to a better prognosis
    Kohei Nakata
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pancreas 40:581-7. 2011
    ..The meaning of "minimal invasion" (MI) in IPMC also remains unclear. We investigated the prognosis of intraductal papillary mucinous neoplasm (IPMN) focusing on MI and subtypes...
  71. doi request reprint Significance of dysadherin and E-cadherin expression in differentiated-type gastric carcinoma with submucosal invasion
    Yoshitomo Maehata
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Hum Pathol 42:558-67. 2011
    ..Combined dysadherin-positive (≥50%) expression and E-cadherin-negative (<50%) expression may be valuable information for predicting aggressive tumor behavior...
  72. doi request reprint Down-regulation of artery in moderately differentiated hepatocellular carcinoma related to tumor development
    Nobuhiro Fujita
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 41:838-47. 2010
    ..The changes of arterial vessel density in moderately differentiated hepatocellular carcinomas were suggested...
  73. doi request reprint Prognostic impact of blood vessel invasion in gastrointestinal stromal tumor of the stomach
    Hidetaka Yamamoto
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hum Pathol 41:1422-30. 2010
    ....
  74. ncbi request reprint Molecular analysis of p53, MDM2, and H-ras genes in osteosarcoma and malignant fibrous histiocytoma of bone in patients older than 40 years
    Ken Ichi Kawaguchi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mod Pathol 15:878-88. 2002
    ..Although the number of patients in this analysis was small, it would appear that MFH-like OS may have some characteristic biologic aspects when compared with osteoblastic OS and MFH of bone in elderly patients...
  75. doi request reprint Overexpression of A disintegrin and metalloproteinase 28 is correlated with high histologic grade in conventional chondrosarcoma
    Suguru Matsuura
    Department of Anatomic Pathology, Graduate School of Medical Science, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 41:343-51. 2010
    ....
  76. doi request reprint HER-2/neu gene amplification in carcinoma ex pleomorphic adenoma in relation to progression and prognosis: a chromogenic in-situ hybridization study
    Kazuki Hashimoto
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Histopathology 60:E131-42. 2012
    ..The aim of this study was to investigate the potential role of HER-2/neu in the stepwise progression of carcinoma ex pleomorphic adenoma (CXPA) and to evaluate its prognostic significance in CXPA...
  77. doi request reprint Antioxidant therapy alleviates oxidative stress by androgen deprivation and prevents conversion from androgen dependent to castration resistant prostate cancer
    Masaki Shiota
    Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Urol 187:707-14. 2012
    ..We elucidated the state and the role of oxidative stress induced by androgen deprivation therapy and the possibility of antioxidant therapy in human prostate cancer...
  78. doi request reprint Hobnail-like cells in serous borderline tumor do not represent concomitant incipient clear cell neoplasms
    Yoshihiro Ohishi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hum Pathol 40:1168-75. 2009
    ..Recognition of our conclusion may protect a patient with "conspicuous hobnail-like cells in serous borderline tumor" from an erroneous overdiagnosis of "concomitant clear cell carcinoma admixed with serous borderline tumor."..
  79. doi request reprint Foxo3a suppression of urothelial cancer invasiveness through Twist1, Y-box-binding protein 1, and E-cadherin regulation
    Masaki Shiota
    Department of Urology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Clin Cancer Res 16:5654-63. 2010
    ..Foxo3a is a member of the Foxo transcription factor family that modulates the expression of various genes. We aimed to elucidate the role of Foxo3a in UC invasion...
  80. doi request reprint Y-box binding protein-1 promotes castration-resistant prostate cancer growth via androgen receptor expression
    Masaki Shiota
    Department of Urology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Endocr Relat Cancer 18:505-17. 2011
    ..In conclusion, these findings suggested that YB-1 induces castration resistance in androgen-dependent PCa cells via AR expression. Thus, YB-1 may be a promising therapeutic target for PCa, as well as CRPC...
  81. doi request reprint Expression and localization of E-cadherin and β-catenin in uterine carcinosarcoma
    Izumi Nishimura
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, 812 8582, Japan
    Virchows Arch 458:85-94. 2011
    ..Furthermore, although the precise mechanism is unclear, nuclear β-catenin expression in sarcomatous components may also be associated with biphasic morphology and heterologous sarcomatous differentiation...
  82. doi request reprint Immunohistochemical characterization of mullerian mucinous borderline tumors: possible histogenetic link with serous borderline tumors and low-grade endometrioid tumors
    Masafumi Yasunaga
    Department of Anatomic Pathology, Graduate School of Medical Science, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Hum Pathol 40:965-74. 2009
    ....
  83. doi request reprint Histologic classification of microscopic portal venous invasion to predict prognosis in hepatocellular carcinoma
    Nobuhiro Fujita
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 42:1531-8. 2011
    ..0259). We proposed a new definition for classifying microscopic portal venous invasion and documented the necessity of definite histologic evaluation of it...
  84. ncbi request reprint Nuclear beta-catenin correlates with cyclin D1 expression in spindle and pleomorphic sarcomas but not in synovial sarcoma
    Tsuyoshi Saito
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hum Pathol 37:689-97. 2006
    ..Thus, cyclin D1 could be considered as one of the targets of the nuclear beta-catenin in spindle cell and pleomorphic sarcomas. A possible association between beta-catenin accumulation and spindle cell morphogenesis may exist in SS...
  85. ncbi request reprint Frequent microsatellite instability in synchronous ovarian and endometrial adenocarcinoma and its usefulness for differential diagnosis
    Eisuke Kaneki
    Department of Anatomic Pathology, Graduate School of Medicine, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, Japan
    Hum Pathol 35:1484-93. 2004
    ..The histological criteria are accurate and useful in most cases; however, in some cases where the relationship between the 2 tumors is difficult to determine, high-resolution MSI analysis may be helpful...
  86. ncbi request reprint Detection of COL1A1-PDGFB fusion transcripts and PDGFB/PDGFRB mRNA expression in dermatofibrosarcoma protuberans
    Tomonari Takahira
    The Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Mod Pathol 20:668-75. 2007
    ..The PDGFB and PDGFRB mRNA expression levels showed a good correlation (r=0.76, P<0.0001). These results indicate that the fusion protein, which is processed by the COL1A1-PDGFB transcripts, can serve as a functional ligand for PDGFRB...
  87. ncbi request reprint Alterations of the p16INK4a/p14ARF pathway in clear cell sarcoma
    Tomonari Takahira
    Department of Anatomic Pathology Second Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Cancer Sci 95:651-5. 2004
    ..3%). All tumors with genetic alterations of the p16INK4a/p14ARF or p53 gene showed a high mitotic rate or tumor necrosis. These alterations were considered to be influential in the poor prognosis of CCS patients...
  88. doi request reprint Neurofibromatosis type 1-related gastrointestinal stromal tumors: a special reference to loss of heterozygosity at 14q and 22q
    Hidetaka Yamamoto
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi Higashi ku, Fukuoka 812 8582, Japan
    J Cancer Res Clin Oncol 135:791-8. 2009
    ....
  89. doi request reprint N-myc downstream regulated gene-1/Cap43 may play an important role in malignant progression of prostate cancer, in its close association with E-cadherin
    YooHyun Song
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 41:214-22. 2010
    ..0175). NDRG1/Cap43 could be a novel marker for malignant progression and poor prognosis in prostate cancer, plausibly in its close association with the down-regulation of E-cadherin expression...
  90. ncbi request reprint Prognostic factors in the so-called malignant mesenchymoma: a clinicopathological and immunohistochemical analysis
    Toshisada Adachi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    Oncol Rep 10:803-11. 2003
    ..In conclusion, a patient age under 40 years and the presence of an RMS component appear to be poor prognostic indicators of survival in patients with so-called MM, and to be a useful adjunct for the classification of these tumors...
  91. doi request reprint Decreased expression of focal adhesion kinase is associated with a poor prognosis in extrahepatic bile duct carcinoma
    Akifumi Hayashi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 41:859-66. 2010
    ..It is important to notice the role of FAK in tumor progression when treatments targeting FAK are performed...
  92. ncbi request reprint Expression of beta-tubulin isotypes in human primary ovarian carcinoma
    Yoshihiro Ohishi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Gynecol Oncol 105:586-92. 2007
    ....
  93. ncbi request reprint Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade
    Norimoto Nakamura
    Department of Anatomic Pathology, Graduate School of Medical Sciences of Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 36:828-37. 2005
    ..Furthermore, alteration of G2-M regulators, such as cyclin A, cyclin B1, and cdc2, is also a useful marker for predicting aggressive behavior and play an important role, at least in part, in the cell proliferation of GIST...
  94. ncbi request reprint The possible role of EWS-Fli1 in evasion of senescence in Ewing family tumors
    Tomoya Matsunobu
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, 812 8582 Fukuoka, Japan
    Cancer Res 66:803-11. 2006
    ....
  95. ncbi request reprint Low-grade fibrosarcoma of the proximal humerus
    Tsuyoshi Saito
    Department of Anatomic Pathology, Kyushu University, Graduate School of Medical Sciences, Fukuoka, Japan
    Pathol Int 53:115-20. 2003
    ..The patient demonstrates no evidence of disease 42 months after surgery. It is important to detect the scant atypical cells for the differential diagnosis of low-grade fibrosarcoma and desmoplastic fibroma of bone...
  96. ncbi request reprint Chromosomal aberrations and microsatellite instability of malignant peripheral nerve sheath tumors: a study of 10 tumors from nine patients
    Chikashi Kobayashi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Cancer Genet Cytogenet 165:98-105. 2006
    ..These findings suggest that chromosomal aberration as a consequence of CIN has a greater role in the pathogenesis of MPNST than does that due to MSI...
  97. ncbi request reprint Cyclin-dependent kinase inhibitor, flavopiridol, induces apoptosis and inhibits tumor growth in drug-resistant osteosarcoma and Ewing's family tumor cells
    Yan Li
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Cancer 121:1212-8. 2007
    ..The treatment with flavopiridol further inhibited the tumor growth in mouse models of the drug-resistant OS and EFTs. These results suggest that flavopiridol might be promising in clinical therapy for the relapsed OS and EFTs...
  98. ncbi request reprint Chondromyxoid fibroma of the clavicle
    Akio Sakamoto
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Orthop Sci 11:533-6. 2006
  99. ncbi request reprint Mixed tumor of deep soft tissue
    Toshisada Adachi
    Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pathol Int 53:35-9. 2003
    ..Histological examination confirmed that the recurrent tumor with an extensive chondroid area invaded the osseous tissue of the fibula. At present, 1 year after the second resection surgery, there is no evidence of disease...
  100. ncbi request reprint H-ras mutation is an additional event of sarcomatous transformation in aerodigestive spindle cell carcinoma
    Hideki Shiratsuchi
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Oncol Rep 11:597-604. 2004
    ....
  101. ncbi request reprint A case of pulmonary synovial sarcoma diagnosed with detection of chimera gene: imaging findings
    Yoshio Matsuo
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka City, Fukuoka Prefecture 812 8582, Japan
    Clin Imaging 30:60-2. 2006
    ..In this case, a lung metastasis could be excluded with fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET), and the final diagnosis was histopathologically confirmed by the chimeric gene detection...