Masaru Morita

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint Technical improvement of total pharyngo-laryngo-esophagectomy for esophageal cancer and head and neck cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 21:1671-7. 2014
  2. doi request reprint Gender differences in prognosis after esophagectomy for esophageal cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 44:505-12. 2014
  3. doi request reprint Surgical resection for esophageal cancer synchronously or metachronously associated with head and neck cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 20:2434-9. 2013
  4. ncbi request reprint Advances in esophageal surgery in elderly patients with thoracic esophageal cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 33:1641-7. 2013
  5. ncbi request reprint Clinical significance of chemoradiotherapy and surgical resection for cT4 esophageal cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 32:3275-82. 2012
  6. ncbi request reprint Expression of FHIT in esophageal epithelium and carcinoma: reference to drinking, smoking and multicentric carcinogenesis
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 26:2243-8. 2006
  7. doi request reprint Acute lung injury following an esophagectomy for esophageal cancer, with special reference to the clinical factors and cytokine levels of peripheral blood and pleural drainage fluid
    M Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Dis Esophagus 21:30-6. 2008
  8. ncbi request reprint Preoperative chemoradiotherapy for esophageal cancer: factors associated with clinical response and postoperative complications
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Anticancer Res 29:2555-62. 2009
  9. doi request reprint In-hospital mortality after a surgical resection for esophageal cancer: analyses of the associated factors and historical changes
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 18:1757-65. 2011
  10. doi request reprint Two-stage operation for high-risk patients with thoracic esophageal cancer: an old operation revisited
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 18:2613-21. 2011

Detail Information

Publications101 found, 100 shown here

  1. ncbi request reprint Technical improvement of total pharyngo-laryngo-esophagectomy for esophageal cancer and head and neck cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 21:1671-7. 2014
    ..The purpose of this study was to clarify the techniques that can decrease the surgical stress and allow for safe reconstruction after this operation...
  2. doi request reprint Gender differences in prognosis after esophagectomy for esophageal cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 44:505-12. 2014
    ..The purpose of this study was to clarify the gender differences in the prognosis, as well as mortality and morbidity, of patients who have undergone esophagectomy for esophageal cancer...
  3. doi request reprint Surgical resection for esophageal cancer synchronously or metachronously associated with head and neck cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 20:2434-9. 2013
    ..The purpose of this study was to clarify the clinical significance of esophagectomy for patients with esophageal cancer associated either synchronously or metachronously with head and neck cancer...
  4. ncbi request reprint Advances in esophageal surgery in elderly patients with thoracic esophageal cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 33:1641-7. 2013
    ..To justify esophagectomy for elderly patients...
  5. ncbi request reprint Clinical significance of chemoradiotherapy and surgical resection for cT4 esophageal cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 32:3275-82. 2012
    ..To clarify the clinical significance of definitive chemoradiotherapy (CRT) and CRT followed by esophagectomy for cT4 esophageal cancer...
  6. ncbi request reprint Expression of FHIT in esophageal epithelium and carcinoma: reference to drinking, smoking and multicentric carcinogenesis
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 26:2243-8. 2006
    ..The purpose of this study was to clarify whether the fragile histidine triad (FHIT) is their target gene in esophageal carcinogenesis as well as in multicentric carcinogenesis...
  7. doi request reprint Acute lung injury following an esophagectomy for esophageal cancer, with special reference to the clinical factors and cytokine levels of peripheral blood and pleural drainage fluid
    M Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Dis Esophagus 21:30-6. 2008
    ..Furthermore, ALI may cause not only SIRS but also other complications such as anastomotic leakage...
  8. ncbi request reprint Preoperative chemoradiotherapy for esophageal cancer: factors associated with clinical response and postoperative complications
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Anticancer Res 29:2555-62. 2009
    ..The factors associated with the clinical results of preoperative chemoradiotherapy (CRT) for esophageal cancer and its effect on postoperative complications are still unclear...
  9. doi request reprint In-hospital mortality after a surgical resection for esophageal cancer: analyses of the associated factors and historical changes
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 18:1757-65. 2011
    ..The object of this study was to clarify the factors associated with in-hospital death while also evaluating any associated historical changes in the characteristics of such deaths...
  10. doi request reprint Two-stage operation for high-risk patients with thoracic esophageal cancer: an old operation revisited
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 18:2613-21. 2011
    ..An esophagectomy followed by reconstruction for esophageal cancer is a highly aggressive operation. The purpose of this study was to justify a two-stage operation for high-risk patients with esophageal cancer...
  11. doi request reprint Repair using the pectoralis major muscle flap for anastomotic leakage after esophageal reconstruction via the subcutaneous route
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 147:212-8. 2010
    ..Anastomotic leakage with an intractable cutaneous fistula frequently develops after an esophagectomy and reconstruction via the subcutaneous route...
  12. doi request reprint Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Int J Clin Oncol 15:126-34. 2010
    ....
  13. doi request reprint Clinical significance of salvage esophagectomy for remnant or recurrent cancer following definitive chemoradiotherapy
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol 46:1284-91. 2011
    ..The purpose of this study was to clarify the effect of preoperative chemoradiotherapy (CRT) for esophageal cancer on the postoperative course, and to determine the clinical significance of salvage esophagectomy after definitive CRT...
  14. doi request reprint Surgical resection following combination chemotherapy with oral S-1 and biweekly docetaxel in a patient with advanced gastric cancer and a prior coronary artery bypass graft with the right gastroepiploic artery: report of a case
    Nobuhide Kubo
    Department of Surgery and Science, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:1531-7. 2011
    ..Therefore, neoadjuvant chemotherapy was effective for preserving the CABG with the RGEA in a patient with advanced gastric cancer...
  15. ncbi request reprint Multimodal treatment strategy for clinical T3 thoracic esophageal cancer
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 20:4267-73. 2013
    ..Our goal was to create a multimodal treatment strategy for patients with locally advanced esophageal cancer (EC)...
  16. ncbi request reprint [A randomized controlled trial to evaluate the effect of adjuvant oral fluoropyrimidine derivative therapy after curative resection for stage II/III rectal cancer-adjuvant chemotherapy trial of S-1 for rectal cancer (ACTS-RC):]
    Eiji Oki
    Dept of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Gan To Kagaku Ryoho 33:138-43. 2006
    ..We aim to include 400 patients in each of the treatment groups and assume that the registration period will last until 2009...
  17. doi request reprint Phase II study of biweekly docetaxel and S-1 combination therapy for advanced or recurrent gastric cancer
    Yoshihiro Kakeji
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Oncology 77:49-52. 2009
    ..This phase II study evaluated the toxicity and efficacy of a novel dosing schedule of docetaxel and S-1 as treatment for advanced gastric cancer...
  18. ncbi request reprint Total laparoscopic distal gastrectomy for elderly patients with gastric cancer
    Eiji Oki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Fukuoka Igaku Zasshi 104:290-8. 2013
    ..This study evaluated the feasibility of totally laparoscopic distal gastrectomy (TLDG) in elderly patients with gastric cancer...
  19. doi request reprint Patterns and time of recurrence after complete resection of esophageal cancer
    Masahiko Sugiyama
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 42:752-8. 2012
    ..The purpose of this study is to clarify the characteristics of recurrence in this patient population...
  20. doi request reprint Loss of heterozygosity at BRCA1 locus is significantly associated with aggressiveness and poor prognosis in breast cancer
    Satoko Okada
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 19:1499-507. 2012
    ..BRCA1 and BRCA2 are two major tumor suppressor genes for hereditary breast and ovarian cancer. In sporadic breast cancer, although somatic mutations of these genes are rare, loss of heterozygosity (LOH) at BRCA1 and BRCA2 loci is common...
  21. ncbi request reprint Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka 812 8582, Japan
    Breast Cancer Res Treat 101:249-57. 2007
    ..Our results suggest that simultaneous PTEN LOH and HER2 overexpression enhances Akt activation and may thus lead to a negative PR expression...
  22. doi request reprint Impact of perioperative peripheral blood values on postoperative complications after esophageal surgery
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 40:626-31. 2010
    ..Prediction of the postoperative course of esophagectomy is an important part of the strict perioperative management of patients undergoing surgery for esophageal cancer...
  23. ncbi request reprint Case of early adenosquamous carcinoma of the stomach
    Yasue Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 104:315-20. 2013
    ..Therefore, future treatment for recurrent adenosquamous carcinoma of the stomach should be considered...
  24. doi request reprint Lymph node metastasis from cancer of the esophagogastric junction, and determination of the appropriate nodal dissection
    Yoshihiro Kakeji
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 42:351-8. 2012
    ..Both squamous cell carcinomas and adenocarcinomas can develop in the esophagogastric junction. To clarify the appropriate lymph node dissection range, lymph node metastases from cancers in the esophagogastric junction were investigated...
  25. ncbi request reprint Activation of PI3K/Akt signaling and hormone resistance in breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Breast Cancer 13:137-44. 2006
    ..Our findings suggest that pAkt may be a useful predictor of resistance to endocrine therapy for breast cancer, while also suggesting that the inhibition of Akt may increase the efficacy of endocrine therapy...
  26. doi request reprint Esophagectomy in patients 80 years of age and older with carcinoma of the thoracic esophagus
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol 43:345-51. 2008
    ..The purpose of this study was to clarify the indications for an esophagectomy in elderly patients (especially patients over 80 years of age) with esophageal cancer...
  27. doi request reprint Podoplanin is expressed at the invasive front of esophageal squamous cell carcinomas and is involved in collective cell invasion
    Yuichiro Nakashima
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Sci 104:1718-25. 2013
    ..05). These data suggest that podoplanin is significantly associated with and likely contributes to ESCC invasion in the absence of EMT...
  28. pmc Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance
    Munkhbold Tuul
    Department of Molecular Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    PLoS ONE 8:e55361. 2013
    ....
  29. doi request reprint FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer
    Ryota Nakanishi
    Department of Molecular Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 19:3627-35. 2012
    ..We investigated the significance of FANCJ expression in CRC, focusing on the effects of 5-FU-based adjuvant chemotherapy...
  30. doi request reprint Advances in esophageal cancer surgery in Japan: an analysis of 1000 consecutive patients treated at a single institute
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 143:499-508. 2008
    ..The object of this study was to evaluate advances in operative therapy for esophageal cancer in Japan...
  31. ncbi request reprint [Hepatic artery infusion chemotherapy to three liver metastasis cases in which systemic chemotherapy was impossible or ineffective]
    Koji Ando
    Dept of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
    Gan To Kagaku Ryoho 35:2192-4. 2008
    ..We herein report three cases that were treated by HAI after initially performing systemic chemotherapy in order to treat liver metastasis from either gastric cancer or colorectal cancer...
  32. doi request reprint Gastric cancer in the reconstructed gastric tube after radical esophagectomy: a single-center experience
    Eiji Oki
    Department of Gastroenterological Surgery, National Kyushu Cancer Center, 3 1 1 Notame, Minami Ku, Fukuoka, 811 1395, Japan
    Surg Today 41:966-9. 2011
    ..This study investigated 10 cases of gastric tube cancer in order to clarify the characteristics and the outcome of these patients...
  33. ncbi request reprint Thoracoscopic pericardial drainage for gastric tube ulcer penetrated into the pericardium
    Masayuki Watanabe
    Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Japan
    Fukuoka Igaku Zasshi 104:389-93. 2013
    ..Thoracoscopic pericardial drainage is useful to manage acute pyogenic pericarditis due to penetration of peptic ulcer which occurred in the gastric tube...
  34. ncbi request reprint Effect of CD133-positive stem cells in repeated recurrence of hepatocellular carcinoma after liver transplantation: a case report
    Takeo Toshima
    Department of Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 104:383-8. 2013
    ..This case illustrates the need for further research to clarify the mutual effect of CD133-positive hepatic stem cells for the development of new therapeutic strategies...
  35. ncbi request reprint Recurrent hepatitis B following recurrence of hepatocellular carcinoma after living donor liver transplantation
    Hideki Ijichi
    Department of Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 104:376-82. 2013
    ..HBV DNA levels increased despite the treatment with anti-HBV agents after HBV recurrence. In hepatitis B surface antigen positive recipients, HBV prophylaxis should be intensified during the treatment of recurrent HCC...
  36. doi request reprint Chemosensitivity and survival in gastric cancer patients with microsatellite instability
    Eiji Oki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 16:2510-5. 2009
    ..This study investigated the usefulness of MSI as either a prognostic indicator or predictor of distinct clinical attributes regarding the use of adjuvant chemotherapy with 5-FU and its analogues in gastric cancer...
  37. ncbi request reprint Trastuzumab and breast cancer: developments and current status
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Science, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Int J Clin Oncol 11:199-208. 2006
    ..In this review, we describe the developments and current status of trastuzumab-based treatment for breast cancer...
  38. doi request reprint High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Breast Cancer 19:161-9. 2012
    ..Loss of heterozygosity (LOH) is thought to reflect random chromosomal instability, and recent studies have shown that DNA-copy number alterations or LOH occur with a high frequency in basal-like and HER2-amplified tumors...
  39. doi request reprint Expanding the applications of microvascular surgical techniques to digestive surgeries: a technical review
    Hideaki Uchiyama
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    Surg Today 42:111-20. 2012
    ..We herein provide a technical review of the application of microvascular surgical techniques for various digestive surgeries...
  40. pmc Checkpoint with forkhead-associated and ring finger promoter hypermethylation correlates with microsatellite instability in gastric cancer
    Eiji Oki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    World J Gastroenterol 15:2520-5. 2009
    ..To examine the methylation status of the promoter region of the checkpoint with forkhead-associated and ring finger (CHFR) and microsatellite mutator status in 59 primary gastric cancers...
  41. doi request reprint The difference in p53 mutations between cancers of the upper and lower gastrointestinal tract
    Eiji Oki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Digestion 79:33-9. 2009
    ..This study investigated the differences in p53 abnormalities between cancers of the upper and lower gastrointestinal tract...
  42. doi request reprint Loss of p53 in esophageal squamous cell carcinoma and the correlation with survival: analyses of gene mutations, protein expression, and loss of heterozygosity in Japanese patients
    Akinori Egashira
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Surg Oncol 104:169-75. 2011
    ..The complexity arises from the different modalities, such as mutation analysis, immunohistochemistry, and the detection of loss of heterozygosity (LOH) at the p53 genomic locus...
  43. doi request reprint Impact of FOXA1 expression on the prognosis of patients with hormone receptor-positive breast cancer
    Yuichi Hisamatsu
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 19:1145-52. 2012
    ..In this study, we evaluated whether forkhead-box protein A1 (FOXA1) expression was a prognostic and predictive marker for HR-positive breast cancer...
  44. ncbi request reprint Rendezvous technique treatment for late-onset biliary leakage after major hepatectomy of a living donor: report of a case
    Koichi Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Fukuoka Igaku Zasshi 104:309-14. 2013
    ..Rendezvous bidirectional drainage effectively treated late-onset bile leakage from the trifurcation of a hepatic bile duct...
  45. doi request reprint Vimentin as a poor prognostic factor for triple-negative breast cancer
    Nami Yamashita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Cancer Res Clin Oncol 139:739-46. 2013
    ..To identify prognostic biomarkers and novel therapeutic targets, vimentin, one of the most major factors associated with EMT was investigated in TNBC...
  46. doi request reprint Laparoscopic resection for gastrointestinal stromal tumors in the stomach
    Yoshihiro Kakeji
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Surg Today 42:554-8. 2012
    ..This study reviewed the use of laparoscopic surgery for gastric partial resection of GISTs or SMTs that were suspected to be GISTs...
  47. doi request reprint Relationship between expression of apoptosis-related proteins and the efficacy of postoperative chemotherapy in patients with T3 gastric cancer
    Shunichi Tsujitani
    Department of Surgery and Science, Graduate School of Medical Science, Kyushu University, Fukuoka, 812 8582, Japan
    Surg Today 42:225-32. 2012
    ..We investigated the relationship between the p53-dependent apoptotic pathway and the survival of patients with gastric cancer, retrospectively, to elucidate new biomarkers of uracil/tegafur (UFT) chemotherapy...
  48. pmc Biological mechanism and clinical effect of protein-bound polysaccharide K (KRESTIN(®)): review of development and future perspectives
    Yoshihiko Maehara
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Surg Today 42:8-28. 2012
    ..Future studies should examine the effects of PSK under different host immune conditions and tumor properties, elucidate the mechanism of action exhibited in each situation, and identify biomarkers...
  49. doi request reprint The impact of a high-frequency microsatellite instability phenotype on the tumor location-related genetic differences in colorectal cancer
    Yan Zhao
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Cancer Genet Cytogenet 196:133-9. 2010
    ..Therefore, instead of tumor location, microsatellite status should be a major focus for the study of colorectal cancers in the future...
  50. ncbi request reprint Risk factors for multicentric occurrence of carcinoma in the upper aerodigestive tract-analysis with a serial histologic evaluation of the whole resected-esophagus including carcinoma
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    J Surg Oncol 83:216-21. 2003
    ..The aim of this study was to elucidate the relationship between the number of carcinomas and risk factors...
  51. doi request reprint Unique variation of the hepatic artery identified on preoperative three-dimensional computed tomography angiography in surgery for gastric cancer: report of a case
    Ryota Nakanishi
    Department of General Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Surg Today 40:967-71. 2010
    ..Preoperative 3D-CT angiography is useful for preventing the complications associated with hepatic artery injury during surgery for gastric cancer...
  52. ncbi request reprint Significance of stroke volume variation during hepatic resection under infrahepatic inferior vena cava and portal triad clamping
    Norifumi Harimoto
    Department of Surgery, Iizuka Hospital, Fukuoka, Japan
    Fukuoka Igaku Zasshi 104:362-9. 2013
    ..The current retrospective study was to investigate SVV and central venous pressure (CVP) during hepatic resection under clamping of both the infrahepatic inferior vena cava (IVC) and the portal triad...
  53. ncbi request reprint Differential expression of insulin-like growth factor 1 in human primary liver cancer
    Yasuharu Ikeda
    Department of Surgery and Science, Faculty of Medicine, Kyushu University, Fukuoka 812 8582, Japan
    Fukuoka Igaku Zasshi 104:334-8. 2013
    ..These results indicate that expression of IGF-1 has the relationship with the differentiation in human primary hepatocellular carcinoma...
  54. doi request reprint Secondary resistance of extra-gastrointestinal stromal tumors to imatinib mesylate: report of a case
    Koji Ando
    Department of Surgery and Science, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:1290-3. 2011
    ..This report provides valuable insight into the mechanisms of recurrent GISTs after treatment with imatinib mesylate...
  55. doi request reprint Copy-neutral loss of heterozygosity at the p53 locus in carcinogenesis of esophageal squamous cell carcinomas associated with p53 mutations
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Clin Cancer Res 17:1731-40. 2011
    ..LOH at the p53 locus has been reported to be associated with esophageal squamous cell carcinogenesis. The aim of this study is to identify potential mechanisms resulting in LOH around the p53 locus in its carcinogenesis...
  56. ncbi request reprint Aberrant hypermethylation of the promoter region of the CHFR gene is rare in primary breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Higashi ku, Japan
    Breast Cancer Res Treat 97:199-203. 2006
    ..We observed the hypermethylation of the CHFR promoter region in only one case (0.9%). We herein show that the aberrant hypermethylation of this region is quite a rare event in primary breast carcinoma...
  57. ncbi request reprint Neoadjuvant chemoradiotherapy for clinical stage II-III esophageal squamous cell carcinoma
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Anticancer Res 31:3073-7. 2011
    ..The clinical significance of neoadjuvant chemoradiotherapy (NACRT) for potentially resectable esophageal squamous cell carcinoma (ESCC) is unclear...
  58. doi request reprint Successful treatment of acute esophageal necrosis caused by intrathoracic gastric volvulus: report of a case
    Noritaka Matsumoto
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 39:1068-72. 2009
    ..Although a large hiatal hernia is usually a chronic disorder, surgical treatment is recommended, considering the risk of serious complications...
  59. ncbi request reprint Clinical significance of cytokeratin positive cells in bone marrow of gastric cancer patients
    Eiji Oki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Cancer Res Clin Oncol 133:995-1000. 2007
    ..Therefore it does not accurately predict the prognosis or recurrence of the disease...
  60. doi request reprint Simultaneous total gastrectomy and endovascular repair of an abdominal aortic aneurysm: report of a case
    Keiji Yoshinaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:721-5. 2011
    ..Despite the patient's medical problems and higher operative risk, he tolerated simultaneous EVAR and total gastrectomy, and had a good outcome after undergoing these simultaneous procedures...
  61. ncbi request reprint Expression of p53 and p21 and the clinical response for hyperthermochemoradiotherapy in patients with squamous cell carcinoma of the esophagus
    Mayumi Ishida
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Anticancer Res 27:3501-6. 2007
    ..The p53 and p21 genes are closely related to sensitivity to chemoradiotherapy. Patients and..
  62. doi request reprint Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Breast Cancer 18:120-3. 2011
    ..The purpose of this study is to investigate the frequency of FANCF methylation, and to discuss its involvement in the pathogenesis of TNBC and its potency as a predictor of cisplatin sensitivity for breast cancer...
  63. ncbi request reprint Application of splenectomy to decompress portal pressure in left lobe living donor liver transplantation
    Toru Ikegami
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Fukuoka Igaku Zasshi 104:282-9. 2013
    ..0.7 +/- 0.4 L/day, p = 0.01) than Group-NS. The cumulative 5-year graft survival rate was 86.8% in Group-S and 76.2% in Group-NS (p = 0.03). In conclusion, splenectomy had beneficial impacts on graft outcomes in left-lobe LDLT...
  64. doi request reprint Initial report of KSCC0803: feasibility study of capecitabine as adjuvant chemotherapy for stage III colon cancer in Japanese patients
    Yasunori Emi
    Department of Surgery, Saiseikai Fukuoka General Hospital, 1 3 46 Tenjin, Chuou ku, Fukuoka, 810 0001, Japan
    Int J Clin Oncol 18:254-9. 2013
    ..A prospective feasibility study was planned to clarify the proportion of compliance and adverse events in the administration of capecitabine as adjuvant chemotherapy for colon cancer in Japanese patients...
  65. doi request reprint A survey of the effects of sivelestat sodium administration on patients with postoperative respiratory dysfunction
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 40:1034-9. 2010
    ..To clarify the clinical significance of sivelestat sodium (SIV) administration, we surveyed the status of 40 patients treated with SIV for respiratory dysfunction following surgery...
  66. doi request reprint Role of tumor-associated macrophages in the progression of hepatocellular carcinoma
    Ken Shirabe
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Surg Today 42:1-7. 2012
    ..This review discusses the roles of TAM in HCC progression and the possibility of new therapies targeting TAMs...
  67. doi request reprint Surgical removal of a denture with sharp clasps impacted in the cervicothoracic esophagus: report of three cases
    Takeo Toshima
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:1275-9. 2011
    ..Thus, we recommend surgery via a cervical approach to remove a denture with sharp clasps impacted in the cervicothoracic esophagus, with intraoperative endoscopic examination for esophageal injury...
  68. doi request reprint High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer
    Koji Ando
    Department of Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Sci 101:639-45. 2010
    ..Collectively, our clinical and in vitro data indicate that high expression of BUBR1 may be one of causative factors for the induction of DNA aneuploidy and progression of gastric cancer...
  69. ncbi request reprint Clinical significance of Smac/DIABLO expression in colorectal cancer
    Kazuya Endo
    Department of Surgery and Science, Kyushu University, Fukuoka 812 8582, Japan
    Oncol Rep 21:351-5. 2009
    ..This study proposes that the decrease of Smac/DIABLO expression is an independent factor determining the poorer prognosis of patients with colorectal cancer...
  70. ncbi request reprint [Two radically resected colorectal carcinoma cases with unresectable liver metastasis after adjuvant chemotherapy with bevacizumab]
    Masahiko Sugiyama
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
    Gan To Kagaku Ryoho 36:2169-71. 2009
    ..Then, both cases were able to undergo radical resections of primary tumor and liver metastases safely...
  71. pmc Differential impact of the expression of the androgen receptor by age in estrogen receptor-positive breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Department of Comprehensive Clinical Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Med 2:763-73. 2013
    ..34, P = 0.0009). AR expression is associated with a less aggressive phenotype and a good prognosis in patients with ER-positive breast cancer. This is considered to be a specific phenomenon for postmenopausal breast cancer patients...
  72. doi request reprint ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity
    Yoshihiko Fujinaka
    Department of Molecular Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    DNA Repair (Amst) 11:247-58. 2012
    ..These results suggest that Rad9- and Rad17-independent activation of the ATR-Chk1 signaling pathway also significantly contributes to 5-FU tolerance...
  73. ncbi request reprint Superdrainage of the ileocolic vein to the internal jugular vein interposed by an inferior mesenteric vein graft in replacing the esophagus with the right hemicolon
    Hideaki Uchiyama
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 40:578-82. 2010
    ..Superdrainage of the ileocolic vein to the internal jugular vein interposed by an IMV graft effectively improves the blood circulation in intestinal conduits brought up to the neck as an esophageal replacement...
  74. ncbi request reprint Comparison of salvage and planned pharyngolaryngectomy with jejunal transfer for hypopharyngeal carcinoma after chemoradiotherapy
    Hideki Kadota
    Department of Otorhinolaryngology and Head and Neck Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Laryngoscope 120:1103-8. 2010
    ..The objective of this study is to examine the safety and efficacy of free jejunal transfer after salvage pharyngolaryngectomy for patients with locally recurrent hypopharyngeal carcinoma after definitive chemoradiotherapy...
  75. ncbi request reprint p53 gene mutations in esophageal squamous cell carcinoma and their relevance to etiology and pathogenesis: results in Japan and comparisons with other countries
    Akinori Egashira
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Cancer Sci 98:1152-6. 2007
    ..In addition, we observed a peculiar sequence of frameshift mutations. Taken together, these data suggest that this tumor suppressor gene plays a critical role in the multistep carcinogenesis process for esophageal squamous cell cancer...
  76. ncbi request reprint Promoter hypermethylation and quantitative expression analysis of CDKN2A (p14ARF and p16INK4a) gene in esophageal squamous cell carcinoma
    Shuhei Ito
    Department of Surgery and Science, Graduate School of Medical Sciences, Japan
    Anticancer Res 27:3345-53. 2007
    ..Abnormal hypermethylation of the CDKN2A (p14ARF and p16INK4a) gene can lead to repression of gene expression and contribute to carcinogenesis and tumor progression...
  77. ncbi request reprint [Fanconi anemia and genomic instability]
    Hiroyuki Kitao
    Department of Molecular Oncology, Graduate School of Medical Sciences, Kyushu University
    Fukuoka Igaku Zasshi 99:115-22. 2008
  78. ncbi request reprint p53 protein accumulation in multiple oesophageal squamous cell carcinoma: relationship to risk factors
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Oncology 62:175-9. 2002
    ..These findings are considered to support the concept of field carcinogenesis of the oesophagus...
  79. doi request reprint Colon metastasis 20 years after the removal of ovarian cancer: Report of a case
    Kotaro Shibahara
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 39:153-6. 2009
    ..The use of immunohistochemistry demonstrated the tumor to be of ovarian origin...
  80. doi request reprint Antagonism of VEGF by genetically engineered dendritic cells is essential to induce antitumor immunity against malignant ascites
    Masahiko Sugiyama
    R and D Laboratory for Innovative Biotherapeutics, Graduate School of Pharmaceutical Sciences, Kyushu University, Rm 505 Collaborative Research Station II, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Mol Cancer Ther 10:540-9. 2011
    ..These findings were not seen in immunodeficient mice, indicating that a VEGF-A/sFLT-1 imbalance is critical for determining the antitumor immune response by DC-vaccination therapy against MA...
  81. doi request reprint Proctocolectomy for colon cancer associated with ulcerative colitis a few months after living donor liver transplantation for primary sclerosing cholangitis: report of a case
    Takasuke Fukuhara
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 39:59-63. 2009
    ..Moreover, surgery, such as radical resection of the colon and rectum should be performed without delay, even shortly after LDLT. To our knowledge, this is the first report of a patient undergoing proctocolectomy after LDLT...
  82. doi request reprint Transient elastography for the prediction of oxaliplatin-associated liver injury in colon cancer patients: a preliminary analysis
    Eiji Oki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Gastrointest Cancer 39:82-5. 2008
    ..However, oxaliplatin-induced liver injury and characterized hepatic hemostatic status can occur after chemotherapy. The assessment of this type of liver injury is often difficult...
  83. ncbi request reprint [Impact of single nucleotide polymorphisms in glutathione S transferase gene GSTP1 in the treatment with oxaliplatin based chemotherapy]
    Eiji Oki
    Dept of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Gan To Kagaku Ryoho 35:1094-6. 2008
    ..Specific roles for the single nucleotide polymorphisms in GST-pi gene GSTP1 in the treatment with oxaliplatin based chemotherapy, have been demonstrated in recent years...
  84. ncbi request reprint Deregulation of the Akt pathway in human cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Curr Cancer Drug Targets 8:27-36. 2008
    ..In this review, we describe Akt signaling pathway components and its cellular functions as well as the alterations in human cancers and the therapeutic approaches for targeting the Akt pathway in cancer...
  85. ncbi request reprint Clinical characteristics of small cell carcinoma of the breast
    Noriaki Sadanaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Oncol Rep 19:981-5. 2008
    ..It is anticipated that an improved understanding of the clinical characteristics of this tumor will result in the development of new therapeutic modalities, which would improve its prognosis...
  86. pmc Colorectal cancer screening with odour material by canine scent detection
    Hideto Sonoda
    Department of Surgery and Science, Kyushu University, Fukuoka, Japan
    Gut 60:814-9. 2011
    ..A study was undertaken using canine scent detection to determine whether odour material can become an effective tool in CRC screening...
  87. ncbi request reprint The association between Akt activation and resistance to hormone therapy in metastatic breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Eur J Cancer 42:629-35. 2006
    ....
  88. ncbi request reprint [Combination chemotherapy of S-1 plus biweekly docetaxel for advanced and recurrent gastric cancer]
    Ikuo Takahashi
    Dept of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Japan
    Gan To Kagaku Ryoho 33:87-90. 2006
    ..The S-1 +biweekly DOC combination therapy can be a candidate for outpatient chemotherapy for advanced or recurrent gastric cancer...
  89. doi request reprint Strategies for treating liver metastasis from gastric cancer
    Yoshihiro Kakeji
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 40:287-94. 2010
    ..Newer generation cytotoxic agents such as S-1, irinotecan, and taxanes show promising activity for patients with metastases. Adjuvant chemotherapy or molecular targeted therapy will provide significant benefits to patients in the future...
  90. ncbi request reprint Risk factors for esophageal cancer and the multiple occurrence of carcinoma in the upper aerodigestive tract
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 131:S1-6. 2002
    ..Recent improvement of molecular biology techniques have helped to show that tumor-suppressor genes, such as p53 and FHIT, may be candidates for target genes of these risk factors...
  91. ncbi request reprint Systemic administration of interleukin-12 can restore the anti-tumor potential of B16 melanoma-draining lymph node cells impaired at a late tumor-bearing state
    M Harada
    Department of Virology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    Int J Cancer 75:400-5. 1998
    ....
  92. doi request reprint Pure laparoscopic right hepatectomy in the semi-prone position using the intrahepatic Glissonian approach and a modified hanging maneuver to minimize intraoperative bleeding
    Tetsuo Ikeda
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 41:1592-8. 2011
    ..The aim of this report is to evaluate the efficiency of a pure laparoscopic right hepatectomy (PLRH) in the semi-prone position using the intrahepatic Glissonian approach and a modified hanging maneuver...
  93. ncbi request reprint Role of the endogenous production of interleukin 12 in immunotherapy
    M Harada
    Department of Virology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    Cancer Res 58:3073-7. 1998
    ....
  94. doi request reprint Microballoon occlusion test to predict colonic ischemia after transcatheter embolization of a ruptured aneurysm of the middle colic artery
    Tsuyoshi Tajima
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, 812 8582, Japan
    Cardiovasc Intervent Radiol 31:828-32. 2008
    ..No colonic ischemia or aneurysm rupture occurred after embolization...
  95. ncbi request reprint Nuclear expression of the Y-box binding protein, YB-1, as a novel marker of disease progression in non-small cell lung cancer
    K Shibahara
    Departments of Medical Biochemistry, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka 812-8582, Japan
    Clin Cancer Res 7:3151-5. 2001
    ..0313) but not in patients with adenocarcinomas. Nuclear localization of the YB-1 protein may prove to be an important factor of disease progression for patients with NSCLC, in particular, in cases of squamous cell carcinoma...
  96. ncbi request reprint Identification of a novel isoform of microphthalmia-associated transcription factor that is enriched in retinal pigment epithelium
    S Amae
    Department of Molecular Biology and Applied Physiology, Tohoku University School of Medicine, Miyagi, Japan
    Biochem Biophys Res Commun 247:710-5. 1998
    ..Moreover, transient cotransfection assays suggested that MITF-A activated transcription of the tyrosinase and tyrosinase-related protein 1 genes. MITF-A/Mitf-a therefore may play an important role in melanogenesis in RPE...
  97. ncbi request reprint [Results of surgical treatment for primary lung cancer; time trends of survival and clinicopathologic features]
    T Osaki
    Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Japan. Yahatanishi-ku, Kitakyushu 807-8555, Japan
    J UOEH 23:277-83. 2001
    ....
  98. ncbi request reprint Expression of Y box-binding protein-1 correlates with DNA topoisomerase IIalpha and proliferating cell nuclear antigen expression in lung cancer
    C Gu
    Department of Surgery II, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan
    Anticancer Res 21:2357-62. 2001
    ..0072; p=0.0168). In contrast, no relationship was found between YB-1 expression and P-gp expression. Our study suggests that YB-1 expression correlates with Topo IIalpha and PCNA expression in lung cancer...
  99. ncbi request reprint Molecular analysis of the cytokine network involved in cachexia in colon 26 adenocarcinoma-bearing mice
    K Yasumoto
    Department of Pharmacology, Hospital Pharmacy, Kanazawa University, Japan
    Cancer Res 55:921-7. 1995
    ..Collectively, additional factor(s) besides IL-1Ra and IL-1 beta may control IL-6 and some other cachexigenic factor production, thereby causing cachexia in this model...
  100. pmc Low expression of polypeptide GalNAc N-acetylgalactosaminyl transferase-3 in lung adenocarcinoma: impact on poor prognosis and early recurrence
    C Gu
    Department of Thoracic and Cardiovascular Surgery, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China
    Br J Cancer 90:436-42. 2004
    ..87 and P=0.019, rr=3.05, respectively). The low expression of GalNAc-T3 may be a useful marker for predicting poor prognosis and early recurrence in completely resected lung carcinoma patients, particularly patients with stage I diseases...
  101. pmc Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking
    K Sugio
    Second Department of Surgery, University of Occupational and Environmental Health, 1 1 Iseigaoka, Kitakyushu, 807 8555 Japan
    Br J Cancer 94:896-903. 2006
    ..In conclusion, the mutations within the tyrosine kinase domain of EGFR were found to specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking...