S Mizuno

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
    S Mizuno
    First Department of Internal Medicine, Kyushu University, Fukuoka, Japan
    Blood 97:1172-9. 2001
  2. ncbi Human thymic epithelial cells maintain long-term survival of clonogenic myeloid and erythroid progenitor cells in vitro
    K Takenaka
    First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Br J Haematol 111:363-70. 2000
  3. ncbi Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway
    M Kawada
    Department of Bioactive Molecules, National Institute of Health, Tokyo, Japan
    Oncogene 15:629-37. 1997
  4. ncbi Coding region structure of interleukin-8 gene of human lung giant cell carcinoma LU65C cells that produce LUCT/interleukin-8: homogeneity in interleukin-8 genes
    K Hotta
    Department of Antibiotics, National Institute of Health, Tokyo, Japan
    Immunol Lett 24:165-9. 1990
  5. ncbi Identification of the sex of a wide range of Carinatae birds by PCR using primer sets selected from chicken EE0.6 and its related sequences
    Y Itoh
    Laboratory of Molecular Biology, Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 1-Tsutsumidori-Amamiyamachi, Aoba-ku, Sendai, Japan
    J Hered 92:315-21. 2001
  6. ncbi The N-terminal internal region of BLM is required for the formation of dots/rod-like structures which are associated with SUMO-1
    H Suzuki
    Molecular Cell Biology Laboratory, Tohoku University, Sendai, Miyagi, 980 8578, Japan
    Biochem Biophys Res Commun 286:322-7. 2001
  7. ncbi Wide distribution of Plasmodium ovale in Myanmar
    T T Win
    Department of International Health, Nagoya University School of Medicine, Nagoya, Japan
    Trop Med Int Health 7:231-9. 2002
  8. ncbi Extravasation on three-dimensional CT angiography in patients with acute subarachnoid hemorrhage and ruptured aneurysm
    M Nakatsuka
    Department of Neurosurgery, Chita Kousei Hospital, Aichi Ken, Japan
    Neuroradiology 44:25-30. 2002
  9. ncbi Chicken spindlin genes on W and Z chromosomes: transcriptional expression of both genes and dynamic behavior of spindlin in interphase and mitotic cells
    Y Itoh
    Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
    Chromosome Res 9:283-99. 2001
  10. ncbi Role of PAF in acute liver injury after extended hepatectomy: overexpression of PAF receptor mRNA in Kupffer cells
    S Mizuno
    First Department of Surgery, Mie University School of Medicine, Tsu, Japan
    Dig Dis Sci 46:1299-304. 2001

Collaborators

Detail Information

Publications25

  1. ncbi Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
    S Mizuno
    First Department of Internal Medicine, Kyushu University, Fukuoka, Japan
    Blood 97:1172-9. 2001
    ..Up-regulated DNMTs may contribute to the pathogenesis of leukemia by inducing aberrant regional hypermethylation. (Blood. 2001;97:1172-1179)..
  2. ncbi Human thymic epithelial cells maintain long-term survival of clonogenic myeloid and erythroid progenitor cells in vitro
    K Takenaka
    First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Br J Haematol 111:363-70. 2000
    ..Our results suggest that thymic cortical epithelial cells have the ability to support not only the differentiation of haematopoietic cells, but also long-term survival of clonogenic myeloid/erythroid progenitor cells...
  3. ncbi Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway
    M Kawada
    Department of Bioactive Molecules, National Institute of Health, Tokyo, Japan
    Oncogene 15:629-37. 1997
    ..Furthermore, we have found that p27Kip1 is phosphorylated by MAP kinase in vitro and the phosphorylated p27Kip1 cannot bind to and inhibit cdk2...
  4. ncbi Coding region structure of interleukin-8 gene of human lung giant cell carcinoma LU65C cells that produce LUCT/interleukin-8: homogeneity in interleukin-8 genes
    K Hotta
    Department of Antibiotics, National Institute of Health, Tokyo, Japan
    Immunol Lett 24:165-9. 1990
    ..Thus, it seems likely that human cells possess IL-8 genes with the homogeneous coding region so that they may first produce the same mature protein with N-terminal AVLPR (= LUCT) which was then truncated...
  5. ncbi Identification of the sex of a wide range of Carinatae birds by PCR using primer sets selected from chicken EE0.6 and its related sequences
    Y Itoh
    Laboratory of Molecular Biology, Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 1-Tsutsumidori-Amamiyamachi, Aoba-ku, Sendai, Japan
    J Hered 92:315-21. 2001
    ..For the two Ratitae species, emu and ostrich, EE0.6 sequences on W and Z chromosomes could not be distinguished either by PCR or Southern blotting...
  6. ncbi The N-terminal internal region of BLM is required for the formation of dots/rod-like structures which are associated with SUMO-1
    H Suzuki
    Molecular Cell Biology Laboratory, Tohoku University, Sendai, Miyagi, 980 8578, Japan
    Biochem Biophys Res Commun 286:322-7. 2001
    ....
  7. ncbi Wide distribution of Plasmodium ovale in Myanmar
    T T Win
    Department of International Health, Nagoya University School of Medicine, Nagoya, Japan
    Trop Med Int Health 7:231-9. 2002
    ..Plasmodium ovale infections were found in villages situated in the southern, central and western regions of Myanmar, suggesting that P. ovale may be widely distributed in this country...
  8. ncbi Extravasation on three-dimensional CT angiography in patients with acute subarachnoid hemorrhage and ruptured aneurysm
    M Nakatsuka
    Department of Neurosurgery, Chita Kousei Hospital, Aichi Ken, Japan
    Neuroradiology 44:25-30. 2002
    ..There were two patterns of extravasation shown by CTA, which seemed to depend on the direction of rupture. Extravasation on CTA might represent the natural progression of ruptured aneurysm and may indicate a poor prognosis...
  9. ncbi Chicken spindlin genes on W and Z chromosomes: transcriptional expression of both genes and dynamic behavior of spindlin in interphase and mitotic cells
    Y Itoh
    Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
    Chromosome Res 9:283-99. 2001
    ..The localization of spindlin in ND10 reappeared after mitosis in daughter cell nuclei. A C-terminal region of spindlin was suggested to be required for the localization of spindlin to ND10...
  10. ncbi Role of PAF in acute liver injury after extended hepatectomy: overexpression of PAF receptor mRNA in Kupffer cells
    S Mizuno
    First Department of Surgery, Mie University School of Medicine, Tsu, Japan
    Dig Dis Sci 46:1299-304. 2001
    ..The PAF produced in the vicinity of Kupffer cells appears to play a very important role as one of the initial mediators of the acute liver injury that occurs after major hepatectomy...
  11. ncbi Transcripts of the MHM region on the chicken Z chromosome accumulate as non-coding RNA in the nucleus of female cells adjacent to the DMRT1 locus
    M Teranishi
    Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
    Chromosome Res 9:147-65. 2001
    ....
  12. ncbi Efficient selection of genomic clones from a female chicken bacterial artificial chromosome library by four-dimensional polymerase chain reactions
    J Kato
    Department of Agricultural and Biological Chemistry, College of Bioresource Sciences, Nihon University, Kameino, Fujisawa, Japan
    Poult Sci 81:1501-8. 2002
    ..This procedure was applied successfully in the selection of BAC clones for Wpkci, chPKCI/HINT, ZOV3, and 17beta-HSD genes...
  13. ncbi Co-localization of chicken DNA topoisomerase IIalpha, but not beta, with sites of DNA replication and possible involvement of a C-terminal region of alpha through its binding to PCNA
    A Niimi
    Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
    Chromosoma 110:102-14. 2001
    ..An in vitro pull-down assay with glutathione-S-transferase-PCNA and (His)6-tagged truncated forms of topo-IIalpha demonstrated that polypeptides containing the above region (residues 1158-1553 or 1158-1294) bound to PCNA in vitro...
  14. ncbi Wpkci, encoding an altered form of PKCI, is conserved widely on the avian W chromosome and expressed in early female embryos: implication of its role in female sex determination
    T Hori
    Laboratory of Molecular Biology, Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, Sendai 981 8555 Japan
    Mol Biol Cell 11:3645-60. 2000
    ..A model is presented suggesting that Wpkci may be involved in triggering the differentiation of ovary by interfering with PKCI function or by exhibiting its unique function in the nuclei of early female embryos...
  15. ncbi Molecular mapping of a new public HLA class I epitope shared by all HLA-B and HLA-C antigens and defined by a monoclonal antibody
    J A Trapani
    Laboratory of Human Immunogenetics, Memorial Sloan Kettering Cancer Center, New York, NY 10021
    Immunogenetics 29:25-32. 1989
    ..These observations are consistent with the notion that gln-144 and arg-151 define a determinant common to HLA-B, HLA-C, and the HLA-Aw19 cross-reactive group and the binding site of the monoclonal antibody 4E...
  16. ncbi Isolation and expression of a cDNA clone encoding HLA-Cw6: unique characteristics of HLA-C encoded gene products
    S Mizuno
    Laboratory of Biochemical Immunogenetics, Memorial Sloan Kettering Cancer Center, New York, NY 10021
    Immunogenetics 29:323-30. 1989
    ..The present study has ruled out differential mRNA splicing as a mechanism for the multiplicity of Cw6 antigens and demonstrated unique HLA-C locus sequences...
  17. ncbi The cDNA cloning and transient expression of a chicken gene encoding a 3 beta-hydroxysteroid dehydrogenase/delta 5-->4 isomerase unique to major steroidogenic tissues
    O Nakabayashi
    Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University, Sendai, Japan
    Gene 162:261-5. 1995
    ..Among the Km values determined for the three substrates, that for dehydroepiandrosterone was the lowest, which was different from the case for human 3 beta-HSD...
  18. ncbi Isolation and expression of a chicken DNA methyltransferase cDNA
    S Tajima
    Institute for Protein Research, Osaka University
    J Biochem 117:1050-7. 1995
    ....
  19. ncbi Purification and primary amino acid sequence of a novel neutrophil chemotactic factor LECT2
    S Yamagoe
    Department of Bioactive Molecules, National Institute of Health, Tokyo, Japan
    Immunol Lett 52:9-13. 1996
    ..Its biological function had not yet been identified. LECT2 and Mim-1 may be involved in the regulation of neutrophil functions in an as yet unidentified way...
  20. ncbi The cDNA cloning and transient expression of a chicken gene encoding cytochrome P-450scc
    O Nomura
    Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University, Sendai, Japan
    Gene 185:217-22. 1997
    ..The chicken cDNA lacks a polyadenylation signal in its 3'-UTR. Sequencing of a 3' end region of the P-450scc gene (CYP11A1) suggests that a region containing the polyadenylation signal is spliced out from the pre-mRNA...
  21. ncbi Expression of a neutrophil chemotactic protein LECT2 in human hepatocytes revealed by immunochemical studies using polyclonal and monoclonal antibodies to a recombinant LECT2
    S Yamagoe
    Department of Bioactive Molecules, National Institute of Infectious Diseases, Tokyo, Japan
    Biochem Biophys Res Commun 237:116-20. 1997
    ..These results indicated that the novel protein was expressed in hepatocytes and suggested an important role of LECT2 in the cells in addition to the activation of neutrophils...
  22. ncbi The cDNA cloning and transient expression of a chicken gene encoding a follicle-stimulating hormone receptor
    N Wakabayashi
    Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University, Sendai, Japan
    Gene 197:121-7. 1997
    ..From these results, we conclude that pcFSHR is a cDNA clone for the chicken FSH-R...
  23. ncbi Molecular cloning of human and bovine LECT2 having a neutrophil chemotactic activity and its specific expression in the liver
    S Yamagoe
    Department of Bioactive Molecules, National Institute of Infectious Diseases, Tokyo, Japan
    Biochim Biophys Acta 1396:105-13. 1998
    ..In addition, several human hepatoma cell lines also expressed LECT2 mRNA, suggesting that hepatic cells in the liver produce LECT2 protein...
  24. ncbi Induction of granulomas in interferon-gamma gene-disrupted mice by avirulent but not by virulent strains of Mycobacterium tuberculosis
    I Sugawara
    Molecular Pathology Division, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo
    J Med Microbiol 47:871-7. 1998
    ..These results suggest that IFN-gamma may be primarily responsible for macrophage activation and that other factor(s) may be involved in the granuloma formation mechanism...
  25. ncbi Prevention of onset of Parkinson's disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson's disease
    H Koike
    Division of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan
    Gene Ther 13:1639-44. 2006
    ..Overall, the present study demonstrated that overexpression of HGF prevented neuronal death in a PD rat model, providing a potential novel therapy for PD...