Tetsuya Mizoue

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..32; 95% CI = 0.12-0.87). The present results underline the potential for selection bias in observational studies, and thus it remains an open question whether screening for stomach cancer is effective...

..The present results suggest that perceived indoor environments, nonspecific symptoms and their associations are closely associated with the season among office workers in a temperate climate...

..Evidence has accumulated concerning the adverse effects of smoking on hearing acuity, but it is not clear whether smoking modifies the association between exposure to noise and hearing loss...

..6 to -0.3). The results of this study support the hypothesis that increased exposure to solar radiation reduces the risk of cancers of the digestive organs...

..A dietary pattern including greater consumption of dairy products and fruits and vegetables with low alcohol consumption may be associated with decreased risk of colorectal adenomas...

..048). A dietary pattern characterized by frequent consumption of dairy products and fruits and vegetables but low alcohol intake may be associated with a decreased risk of developing a glucose tolerance abnormality...

..The interaction of smoking and BMI reached statistical significance (P = 0.04). Leanness may enhance oxidative DNA damage induced by smoking and thus serve as a marker of host susceptibility to smoking-related cancers...

..It is unclear whether tobacco smoking is related to colorectal cancer risk in Japan. We evaluated the association among the Japanese population based on a systematic review of epidemiologic evidence...

..To estimate stroke mortality and evaluate risk factors for total stroke deaths and its two principal subtypes in a cohort study in Japan...

..01). A positive association between CRP and prevalence odds of large adenomas was not modified by either smoking or overweight. These findings suggest that inflammation is linked to the growth of colorectal adenomas...

..34-0.92, trend P=0.02). Our findings do not support the hypothesis that consumption of red meat increases colorectal cancer risk but do suggest that high intake of fish may decrease the risk, particularly of distal colon cancer...

..Despite a declining incidence, stomach cancer is still a dominant cancer in Japan. The association between dietary habits and stomach cancer risk was investigated in a large prospective study in Japan...

..Many studies have reported the relation of specific foods and nutrients to inflammation, but few studies have examined the relation of dietary patterns to inflammatory markers...

..03). The present study suggests that variation in activity and inducibility of CYP2E1, in relation to alcohol or red meat intake, contributes to the development of colorectal cancer...

..55, 95% CI = 0.33-0.93). It is unlikely that acetaldehyde metabolism determined by ALDH2 polymorphism contributes to the risk of colorectal cancer, whereas the role of ADH2 polymorphism deserves further investigation...

..We investigated the relationship between the intake of fish and the risk of death from prostate cancer...

..The present study adds to evidence that high levels of circulating vitamin D measured during darker season is associated with decreased prevalence of adenomas in the distal sites of the colorectum...

..The Japan Collaborative Cohort Study (JACC Study) provided an opportunity to examine the association between smoking and the risk of mortality due to stomach cancer...

..g. hepatitis C virus infection) and genetic traits (e.g. presence of poor acetaldehyde metabolizers)...

..The objective of this study was to examine the mortality and incidence of stomach cancer in the Japan Collaborative Cohort Study (JACC Study), and compare them with those of the general population of Japan...

..Emerging epidemiologic data suggest that cigarette smoking may increase the risk of primary liver cancer. We evaluated this association based on a systematic review of epidemiologic evidence among Japanese populations...

..On the basis of a systematic review of epidemiological evidence, we evaluated this association among the Japanese population, who may be more susceptible to alcohol-related diseases than Western populations...

..Smoking is responsible for a considerable proportion of deaths due to all causes as well as cause-specific deaths. Population-based antismoking programs should be implemented to reduce such avoidable deaths...

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..To re-assess this issue, we reviewed data from Japanese epidemiological studies...

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..Therefore, we examined the associations of XRCC1 Arg399Gln, Arg280His, and Arg194Trp polymorphisms with colorectal cancer and the impact of the association between alcohol consumption and colorectal cancer risk...

..To examine the relation of green tea consumption with oral carcinogenesis, we prospectively analyzed data from a nationwide large-scale cohort study in Japan...

..Alcohol use may confer increased risks not only of type 2 diabetes mellitus but also of preceding glucose intolerance status. Smoking does not seem to deteriorate glucose tolerance...

..We investigated associations of dietary fiber and source foods with colorectal cancer risk in the Fukuoka Colorectal Cancer Study, a community-based case-control study...

..13-1.06), respectively. Our study reveals an inverse association between vegetable consumption and the risk of death from liver cancer. These results provide further evidence of the protective effect of vegetables against liver cancer...

..Because very few individuals had the 1298CC genotype, the findings regarding the A1298C polymorphism need careful interpretation and confirmation in larger studies...

..However, benefit of colorectal polypectomy in routine practice is still uncertain. We therefore investigated subsite-specific risks of colorectal cancer in relation to history of colorectal polypectomy in a case-control study...

..We estimated the burden of cancer using mortality and years of life lost according to life tables in a cohort study in Japan...

..Our results implied that self-management skills might have the potential of affecting the mental health of Japanese employees...

..Recent studies also suggest that obesity may play a role in the development of liver cancer in alcoholic cirrhosis or viral hepatitis and in the general population...

..Thus the metabolic syndrome appears to be an important entity with regard to the prevention of colorectal cancer, as well as cardiovascular disease and type 2 diabetes...

..The results of the present study indicate that physical activity associated with work and leisure-time exerts beneficial effects in Japanese, but not on the proximal colon...

..We investigated the association between major dietary patterns and glucose tolerance status as measured by A1C in Japanese adults...

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..In women, there was no significant association between any of the indices of physical activity. In conclusion, leisure-time exercise and walking or cycling during commuting to work may be associated with better mental health in men...

..To validate the Japanese version of the Oral Health Impact Profile (OHIP-J) for use among young and middle-aged adults. Evaluating the criterion validity was particularly important in this study...

..3, 4.3) and 2.6 (95% CI: 1.1, 6.2), respectively. The importance of these observations lie in its potential for improving physician and public awareness of psychosocial factors as an early indication of mental health morbidity...

..To explain the correlation between socioeconomic status and stomach cancer, we therefore examined the roles played by different lifestyle factors...

..1). In conclusion, our study suggests that extended hours of VDT use might be related to increased SBS symptoms. Moreover, psychosocial distress related to VDT work might mediate the relationship between VDT use and SBS symptoms in women...

..The U-shaped relations of hours of overtime work to overall cigarette consumption and addiction to smoking deserve further investigations...

..Our results implied that communication skill training might have a favorable effect on burnout among Japanese hospital nurses...

..This suggests that walking exercise may not achieve the beneficial effect on lipids profiles among middle-aged/older Japanese...

..The study provided suggestive evidence for a protective association between adiponectin and large adenomas, but did not indicate a protective association independent of adiposity...

..Informed consent to genotyping was obtained from 685 cases and 778 controls. Further details of the design and conduct are described with respect to methodological aspects...

..CONCLUSIONS: The results indicated that intake of sweet drinks is a determinant of oral health status, independent of dental health behavior, particularly among males...

..CONCLUSION: An increased, albeit nonsignificant, risk of childhood hematological malignancies associated with residential proximity to high-voltage power lines warrants further investigations...

..The aim of this study was to investigate the relationship between coffee and green tea consumption and glucose tolerance status as determined using a 75-g OGTT...

..To prospectively examine the association of cigarette smoking and alcohol drinking with oral and pharyngeal carcinogenesis, we analyzed data from a nation-wide large-scale cohort study in Japan...

..Our results implied that age, job rank, communication with superiors and self-management skills would contribute to the mental health of Japanese employees...

..2 VS. 14.2 per 100,000). The present findings are the first results of cancer mortality from Viet Nam and should be useful for further cancer control programs there...

..6-0.8). Dose response relationships between smoking and these variables were also observed. The results indicated that cigarette smoking was associated with oral health status independent of some aspects of dental health behavior...

..This study examined the relationship between the extent of worksite smoking restriction and worker attitudes toward these policies...

..The purpose of the present study was to examine the association between diabetes and liver cancer in view of the trend and the interaction...

..Smoking has not been confirmed as a risk factor for cancers of the liver and stomach. The authors examined prospectively the relationship between smoking and these cancers in an endemic region...

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..The aim of this paper is to develop a short version of the Japanese OHIP (OHIP-J) appropriate for use in young and middle-aged adults, and to evaluate its properties using cross-sectional data...

..An oral health promotion program has been conducted since 1989 at a shipyard in Japan...

..3-11.8). The high consumption of pickled food and traditional soups also increased risk, but not significantly. The findings suggest that a diet high in salt and low in vitamins may be associated with an increase in stomach cancer...

..The second and third oblique factors, defined almost entirely by the STAI-Y anxiety-present items, clearly reflected the state-trait distinction in this sample of Japanese workers...

..The purpose of this study was to examine whether such a history correlates with the development of liver cancer among the general population of this high-endemic area...

..The aim of this study is to evaluate the magnitude of the aggregation of a stomach cancer history in parents and their offspring in comparison with that of a history at other sites...

..Any preventive strategy should take into account the degree of individual susceptibility...

..In Japan, green tea has been drunk for a long time. Because it can be drunk casually, many people love drinking it. If such green tea has an effect to prevent stomach cancer, it will be a very convenient way to prevent the disease...

..New biomarkers of the disease that may contribute to establish the potential screening strategy would be of value for the early detection of individuals at high risk of the disease...

..Helicobacter pylori infection and serum pepsinogen values are strongly related with stomach cancer. The aim of this study was to know what were these factors among general population...

..Additionally, men who participated but had lower interest in health screening are also considered as high risk for cardiovascular disease...

..We evaluated the association between tobacco smoking and total cancer risk among Japanese populations based on a systematic review of epidemiological evidence...

..Most of the leukemia cases in the highest exposure category had MF levels far above 0.4 microT. Our results provided additional evidence that high MF exposure was associated with a higher risk of childhood leukemia, particularly of ALL...

..It would be of value, therefore, to quantify that association in Japan based on a systematic review of epidemiological evidence for the primary prevention of lung cancer...

..We conducted a systematic review of epidemiological evidence to evaluate the association between alcohol drinking and total cancer risk among the Japanese population...

..Based on a systematic review of epidemiologic evidence, we evaluated this association among the Japanese population, who may be more susceptible to alcohol-related diseases than Western populations...

..We examined cross-sectional associations between the intake of folate, other B vitamins, and omega-3 PUFAs and depressive symptoms in Japanese adults...

..These findings would be beneficial in the workplace for selection of subjects who should be encouraged to undergo pulse oximetry for detection of SDB...

..This report is one of a series of articles by our research group, which is evaluating the existing evidence concerning the association between health-related lifestyles and cancer...

..We evaluated the association between tobacco smoking and gastric cancer risk among the Japanese population based on a systematic review of epidemiologic evidence...

..An alcohol-colorectal cancer association seems to be more apparent in Japanese than in Western populations. Whether this difference can be ascribed to genetic or environmental factors needs to be clarified...

..In conclusion, serum TGFbeta1 levels were not associated with increased risks of subsequent stomach cancer.gene A52C polymorphism related to the metabolism of long-chain fatty acids and oxidized LDL in the etiology of colorectal cancer...

..As tobacco smoking may be one of the few modifiable risk factors for breast cancer, we focused on the association between tobacco smoking and the risk of breast cancer in this review...

..7% increase). The results based on a longitudinal observation suggest that weight loss is associated with increased oxidative DNA damage, a state presumably related to an increased risk of cancer...