Research Topics
Species | A MatsuzakiSummaryAffiliation: Kyushu University Country: Japan Publications
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Detail Information
Publications
Prognostic factors for relapsed childhood acute lymphoblastic leukemia: impact of allogeneic stem cell transplantation--a report from the Kyushu-Yamaguchi Children's Cancer Study GroupAkinobu Matsuzaki
Division of Child Health, School of Health Sciences, Kyushu University, Fukuoka, Japan
Pediatr Blood Cancer 45:111-20. 2005..In particular, an attempt was made to clarify whether stem cell transplantation (SCT) had any advantages over chemotherapy...
Long-term outcome of treatment with protocols AL841, AL851, and ALHR88 in children with acute lymphoblastic leukemia: results obtained by the Kyushu-Yamaguchi Children's Cancer Study GroupA Matsuzaki
Division of Child Health, School of Health Sciences, Kyushu University, Fukuoka, Japan
Int J Hematol 73:369-77. 2001....
Immune response after influenza vaccination in children with cancerAkinobu Matsuzaki
Division of Child Health, School of Health Sciences, Kyushu University, Fukuoka, Japan
Pediatr Blood Cancer 45:831-7. 2005..To assess the immune response to inactivated trivalent split influenza vaccine in children with cancer...
Fatal visceral varicella-zoster virus infection without skin involvement in a child with acute lymphoblastic leukemiaAkinobu Matsuzaki
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Pediatr Hematol Oncol 25:237-42. 2008..VZV infection should be considered in patients with unexplained liver dysfunction under severe immunosuppressive condition, even in the absence of viral exposure and skin involvement...
Immunotherapy with autologous dendritic cells and tumor-specific synthetic peptides for synovial sarcomaAkinobu Matsuzaki
Department of Pediatrics, Graduate School of Medical Sciences, Fukuoka, Japan
J Pediatr Hematol Oncol 24:220-3. 2002..The CD3+ cells cultured with pulsed DCs lysed tumor cells in vitro. Immunotherapy using DCs and tumor-specific peptides may be a safe approach in the treatment of childhood cancer...
Long-term use of peripherally inserted central venous catheters for cancer chemotherapy in childrenAkinobu Matsuzaki
Division of Child Health, School of Health Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
Support Care Cancer 14:153-60. 2006..The purposes of this study are to assess the feasibility of PICCs and to determine the risk factors for PICC-related complications in pediatric patients with various types of malignancies...
Outcome of acute lymphoblastic leukemia in children with AL90 regimen: impact of response to treatment and sex difference on prognostic factorsE Ishii
Division of Pediatrics, Hamanomachi Hospital, Fukuoka, Japan
Med Pediatr Oncol 37:10-9. 2001..In our previous studies, the outcome of high-risk ALL was still poor. In the present study, all children with ALL were classified into three groups and treated with a new regimen (AL90)...
Treatment of childhood acute myelogenous leukemia with allogeneic and autologous stem cell transplantation during the first remission: a report from the Kyushu-Yamaguchi Children's Cancer Study group in JapanA Matsuzaki
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Pediatr Hematol Oncol 17:623-34. 2000..1 +/- 7.9%, 41.6 +/- 19.7%, and 83.3 +/- 15.2%, respectively. The outcome of allo BMT was superior to that of autograft. Auto BMT rather than PBSCT might contribute to a long-term survival in case of no available HLA-identical siblings...
Treatment of standard-risk acute lymphoblastic leukemia in children: the results of protocol AL841 from the Kyushu-Yamaguchi Children's Cancer Study Group in JapanA Matsuzaki
Department of Pediatrics, Kyushu University, Fukuoka, Japan
Pediatr Hematol Oncol 16:187-99. 1999..0% at diagnosis to 35.2% (median). The protocol AL841 provided good long-term disease control without severe late cardiac dysfunction...
Selective cytotoxicity of phospholipids and diacylglycerols to rat 3Y1 fibroblasts transformed by adenovirus type 12 or its E1A geneH Shimura
Department of Virology, Kyushu University, Fukuoka, Japan
Cancer Res 48:578-83. 1988....
An infant with precursor natural killer (NK) cell leukemia successfully treated with an unrelated cord blood transplantationA Suminoe
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Leuk Lymphoma 39:641-6. 2000..He has remained in complete remission for 14 months posttransplant. To our knowledge, this is the youngest reported case with precursor NK cell leukemia; cord blood transplantation may thus be the treatment of choice for this disease...
Unrelated cord blood transplantation for an infant with chemotherapy-resistant progressive Langerhans cell histiocytosisA Suminoe
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
J Pediatr Hematol Oncol 23:633-6. 2001..The authors suggest that CBT could be considered in the treatment of patients with chemotherapy-resistant progressive LCH, especially if there are no available human leukocyte antigen-matched family donors...
Quantitative monitoring of circulating Epstein-Barr virus DNA for predicting the development of posttransplantation lymphoproliferative diseaseS Ohga
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Int J Hematol 73:323-6. 2001..Sequential monitoring of circulating EBV-DNA by quantitative PCR may be a useful indicator for predicting the development of posttransplantation LPD...
Suppression of block to entry into S phase in cell-cycle mutants of rat 3Y1 fibroblasts after transformation by adenovirus type 12A Matsuzaki
Department of Virology, Kyushu University, Fukuoka, Japan
Virology 165:57-65. 1988....
High expression of platelet-derived growth factor and transforming growth factor-beta 1 in blast cells from patients with Down Syndrome suffering from transient myeloproliferative disorder and organ fibrosisH Hattori
Department of Paediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Br J Haematol 115:472-5. 2001..The expression of TGF-beta 1 gene was higher in TMD and acute megakaryoblastic leukaemia than in the control group. These results suggest that PDGF in combination with TGF-beta 1 plays a role in organ fibrosis of TMD...
Haptoglobin therapy for acute favism: a Japanese boy with glucose-6-phosphate dehydrogenase GuadalajaraS Ohga
Department of Paediatrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Br J Haematol 89:421-3. 1995..Haptoglobin treatment might be helpful for managing the haemolytic crisis in the disease...
Mechanism of selective killing by dilinoleoylglycerol of cells transformed by the E1A gene of adenovirus type 12A Matsuzaki
Department of Virology, Kyushu University, Fukuoka, Japan
Cancer Res 49:5702-7. 1989....
Polymorphisms of transforming growth factor-beta1 and transforming growth factor-beta1 type II receptor genes are associated with acute graft-versus-host disease in children with HLA-matched sibling bone marrow transplantationH Hattori
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Bone Marrow Transplant 30:665-71. 2002..16; P = 0.01). In conclusion, genetic backgrounds of TGF-beta1 and TGF-beta1 RII may be involved in the development of aGVHD in HLA-matched sibling BMT in Japanese children...
The laminin-derived peptide YIGSR (Tyr-Ile-Gly-Ser-Arg) inhibits human pre-B leukaemic cell growth and dissemination to organs in SCID miceN Yoshida
Department of Pediatrics, Saga Medical School, Japan
Br J Cancer 80:1898-904. 1999..These data suggest that the multimeric YIGSR peptide can inhibit the tumour growth and metastasis of leukaemic cells and may be useful as a potential therapeutic reagent for leukaemic infiltrations...
[A case showing effective radiotherapy for a radiation-induced glioblastoma]K Fukui
Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 815-8582, Japan
No Shinkei Geka 29:673-7. 2001..The residual tumor disappeared after the radiotherapy, and her status is still "complete remission", 29 months after the onset...
Neutrophil-derived TNF-related apoptosis-inducing ligand (TRAIL): a novel mechanism of antitumor effect by neutrophilsYuhki Koga
Department of Pediatrics, Graduate School of Medical Sciences, School of Health Sciences, Kyushu University, Fukuoka, Japan
Cancer Res 64:1037-43. 2004..Neutrophils may exert their own antitumor effect by TRAIL. A microarray analysis was found to be a useful tool for detecting novel genes that are suggested to play unknown roles in the neutrophil function...
Expression of cytokine-associated genes in dendritic cells (DCs): comparison between adult peripheral blood- and umbilical cord blood-derived DCs by cDNA microarrayYuhki Koga
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
Immunol Lett 116:55-63. 2008....
Treatment-related acute myelomonocytic leukemia with t(11;19) in a child following chemotherapy for hepatoblastomaYuhki Koga
Pediatr Blood Cancer 50:943-4. 2008
Human herpesvirus 6 (HHV-6)-associated pleurisy after unrelated cord blood transplantation in children with chemotherapy-resistant malignant LymphomaAiko Suminoe
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
J Pediatr Hematol Oncol 29:709-12. 2007..Quantitative polymerase chain reaction is a useful tool for rapid detection of viral DNA, which may facilitate precise diagnosis and appropriate treatment...
Regulatory polymorphisms of multidrug resistance 1 (MDR1) gene are associated with the development of childhood acute lymphoblastic leukemiaHiroyoshi Hattori
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
Leuk Res 31:1633-40. 2007..04). The present study suggests that the genetic background of MDR1 may be associated with the development of childhood ALL, possibly due to a quantitative change in the MDR1 gene resulting from genetic polymorphisms...
[Alveolar rhabdomyosarcoma of unknown origin mimicking acute leukemia at the initial presentation]Kan Yamaguchi
Department of Pediatrics, Kyushu University Hospital, Kyushu University
Rinsho Ketsueki 48:315-20. 2007..Alveolar rhabdomyosarcoma often develops in older children and younger adults, and its bone marrow infiltration may mimic acute leukemia...
Identification of novel genes with prognostic value in childhood leukemia using cDNA microarray and quantitative RT-PCRHiroyoshi Hattori
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Pediatr Hematol Oncol 23:115-27. 2006..The present results suggest that a combination of cDNA microarray and quantitative RT-PCR may be useful to identify novel genes with prognostic value in childhood AML...
Differential mRNA expression of glucocorticoid receptor alpha and beta is associated with glucocorticoid sensitivity of acute lymphoblastic leukemia in childrenYuhki Koga
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Pediatr Blood Cancer 45:121-7. 2005..Alternative splicing of the glucocorticoid receptor (GR) gene results in several isoforms. We examined an association of the expression pattern of GR isoforms in leukemic blasts with their sensitivity to glucocorticoid in childhood ALL...
Expression of matrix metalloproteinase (MMP) and tissue inhibitor of MMP (TIMP) genes in blasts of infant acute lymphoblastic leukemia with organ involvementAiko Suminoe
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Leuk Res 31:1437-40. 2007..005 and 0.009) and between CNS involvement and the MMP-2/TIMP-2 ratio (p=0.012). The results suggest that MMP/TIMP balance is closely related to the infiltration of leukemia cells into extramedullary organs...
Reversible posterior leukoencephalopathy syndrome in children with cancersAiko Suminoe
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
J Pediatr Hematol Oncol 25:236-9. 2003..Early recognition of RPLS as a complication during cancer therapy in childhood may facilitate precise diagnosis and appropriate treatment...
Congenital Ewing sarcoma in retroperitoneum with multiple metastasesYusuke Saito
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Pediatr Blood Cancer 51:698-701. 2008..EWS-FLI1 fusion gene was detected by RT-PCR, indicating Ewing sarcoma. She received chemo-radiotherapy and survived for 2 years and 10 months despite the multiple metastases at initial presentation...
