Kiyoshi Matsumura

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. doi request reprint Impact of antihypertensive medication adherence on blood pressure control in hypertension: the COMFORT study
    K Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    QJM 106:909-14. 2013
  2. ncbi request reprint Does a combination pill of antihypertensive drugs improve medication adherence in Japanese? A randomized controlled trial
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Circ J 76:1415-22. 2012
  3. ncbi request reprint Gender-related association of serum uric acid and left ventricular hypertrophy in hypertension
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Circ J 70:885-8. 2006
  4. ncbi request reprint Prolongation of the QT interval in primary aldosteronism
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Exp Pharmacol Physiol 32:66-9. 2005
  5. ncbi request reprint Association of QT interval with blood pressure in 80-year-old subjects
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 27:387-91. 2004
  6. ncbi request reprint Changes in blood pressure and heart rate variability during dental surgery
    K Matsumura
    Department of Internal Medicine, Kyushu Dental College, Kitakyushu, Japan
    Am J Hypertens 11:1376-80. 1998
  7. ncbi request reprint Neural regulation of blood pressure by leptin and the related peptides
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Regul Pept 114:79-86. 2003
  8. ncbi request reprint Central ghrelin modulates sympathetic activity in conscious rabbits
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertension 40:694-9. 2002
  9. ncbi request reprint Central alpha-melanocyte-stimulating hormone acts at melanocortin-4 receptor to activate sympathetic nervous system in conscious rabbits
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 12 8582, Japan
    Brain Res 948:145-8. 2002
  10. ncbi request reprint Association of body mass index with blood pressure in 80-year-old subjects
    K Matsumura
    Department of Internal Medicine, Kyushu Dental College, Kitakyushu, Japan
    J Hypertens 19:2165-9. 2001

Collaborators

Detail Information

Publications71

  1. doi request reprint Impact of antihypertensive medication adherence on blood pressure control in hypertension: the COMFORT study
    K Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    QJM 106:909-14. 2013
    ..It has not been fully elucidated whether antihypertensive medication adherence affects blood pressure (BP) control in hypertension cases...
  2. ncbi request reprint Does a combination pill of antihypertensive drugs improve medication adherence in Japanese? A randomized controlled trial
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Circ J 76:1415-22. 2012
    ..Whether antihypertensive treatment with a single pill combining antihypertensive drugs would improve medication adherence and blood pressure control was investigated...
  3. ncbi request reprint Gender-related association of serum uric acid and left ventricular hypertrophy in hypertension
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Circ J 70:885-8. 2006
    ..The aim of the present study was to determine whether sex differences contribute to the association of serum uric acid and left ventricular hypertrophy in individuals with hypertension...
  4. ncbi request reprint Prolongation of the QT interval in primary aldosteronism
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Exp Pharmacol Physiol 32:66-9. 2005
    ..54; r=-0.1500). 5. Our results indicate that the QTc interval is prolonged in patients with primary aldosteronism, probably owing to hypokalaemia...
  5. ncbi request reprint Association of QT interval with blood pressure in 80-year-old subjects
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 27:387-91. 2004
    ..The association between the QTc interval and SBP was highly statistically significant in all analyses. These results show that SBP by itself may influence the QTc interval in very old subjects...
  6. ncbi request reprint Changes in blood pressure and heart rate variability during dental surgery
    K Matsumura
    Department of Internal Medicine, Kyushu Dental College, Kitakyushu, Japan
    Am J Hypertens 11:1376-80. 1998
    ....
  7. ncbi request reprint Neural regulation of blood pressure by leptin and the related peptides
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Regul Pept 114:79-86. 2003
    ....
  8. ncbi request reprint Central ghrelin modulates sympathetic activity in conscious rabbits
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertension 40:694-9. 2002
    ....
  9. ncbi request reprint Central alpha-melanocyte-stimulating hormone acts at melanocortin-4 receptor to activate sympathetic nervous system in conscious rabbits
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 12 8582, Japan
    Brain Res 948:145-8. 2002
    ..These results suggest that intracerebroventricularly administered alpha-MSH acts at the melanocortin-4 receptor in the brain and activates sympathetic outflow, resulting in an increase in arterial pressure...
  10. ncbi request reprint Association of body mass index with blood pressure in 80-year-old subjects
    K Matsumura
    Department of Internal Medicine, Kyushu Dental College, Kitakyushu, Japan
    J Hypertens 19:2165-9. 2001
    ..The aim of the present study was to determine the association between body mass index (BMI) and blood pressure in 80-year-old subjects...
  11. ncbi request reprint Role of aldosterone in left ventricular hypertrophy in hypertension
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Am J Hypertens 19:13-8. 2006
    ..The aim of the present study was to determine the role of aldosterone in LV geometry and to investigate other types of target organ damage in hypertensive patients...
  12. ncbi request reprint Role of AT1 receptors in area postrema on baroreceptor reflex in spontaneously hypertensive rats
    K Matsumura
    Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Brain Res 850:166-72. 1999
    ....
  13. ncbi request reprint Central effects of leptin on cardiovascular and neurohormonal responses in conscious rabbits
    K Matsumura
    Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka 812 8582, Japan
    Am J Physiol Regul Integr Comp Physiol 278:R1314-20. 2000
    ..These results suggest that intracerebroventricular leptin acts in the central nervous system and activates sympathoadrenal outflow, resulting in increases in arterial pressure and plasma glucose levels in conscious rabbits...
  14. ncbi request reprint Central cardiovascular action of neuropeptide Y in conscious rabbits
    K Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertension 36:1040-4. 2000
    ....
  15. ncbi request reprint Subtypes of metabotropic glutamate receptors in the nucleus of the solitary tract of rats
    K Matsumura
    Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, Japan
    Brain Res 842:461-8. 1999
    ....
  16. ncbi request reprint Central orexin-A augments sympathoadrenal outflow in conscious rabbits
    K Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertension 37:1382-7. 2001
    ..These results suggest that intracerebroventricular orexin-A acts in the central nervous system and activates sympathoadrenal outflow, resulting in increases in arterial pressure and plasma glucose levels in conscious rabbits...
  17. ncbi request reprint Lack of association between QT dispersion and blood pressure response during dental surgery
    K Matsumura
    Department of Internal Medicine, Kyushu Dental College, Kitakyushu, Japan
    Clin Exp Pharmacol Physiol 28:748-51. 2001
    ..4. These results suggest that QTc dispersion is not associated with the power spectrum of R-R variability and that it does not affect the blood pressure response during tooth extraction...
  18. ncbi request reprint Central adrenomedullin augments the baroreceptor reflex in conscious rabbits
    K Matsumura
    Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Hypertension 33:992-7. 1999
    ..These results suggest that central adrenomedullin and CGRP, but not PAMP, participate in cardiovascular regulation to augment the baroreflex controls of renal sympathetic nerve activity and heart rate in conscious rabbits...
  19. ncbi request reprint Central human cocaine- and amphetamine-regulated transcript peptide 55-102 increases arterial pressure in conscious rabbits
    K Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertension 38:1096-100. 2001
    ....
  20. doi request reprint QT interval prolongation and the risks of stroke and coronary heart disease in a general Japanese population: the Hisayama study
    Daisuke Maebuchi
    Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 33:916-21. 2010
    ..Measurement of QTc intervals is likely to provide additional information for the detection of individuals at high risk of future CVD events...
  21. doi request reprint Does decreased diastolic blood pressure associate with increased mortality in 80-year-old Japanese?
    Shuntaro Kagiyama
    Division of General Internal Medicine, Department of Health Promotion, Science of Health Improvement, Kyushu Dental College, Kitakyushu, Japan
    Clin Exp Hypertens 31:639-47. 2009
    ..These results suggest that decreased DBP is associated with higher mortality in the Japanese elderly...
  22. doi request reprint Improvement of blood pressure control in a hypertension clinic in Japan: a 15-year follow-up study
    Yuko Ohta
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Clin Exp Hypertens 31:553-9. 2009
    ....
  23. ncbi request reprint Chronic central infusion of orexin-A increases arterial pressure in rats
    Yingzi Lin
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Brain Res Bull 57:619-22. 2002
    ....
  24. ncbi request reprint Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats
    Yingzi Lin
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Hypertension 43:977-82. 2004
    ..These results suggest that ghrelin acts at the nucleus of the solitary tract to suppress sympathetic activity and to decrease arterial pressure in rats...
  25. doi request reprint Impact of blood pressure levels on different types of stroke: the Hisayama study
    Hisatomi Arima
    Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University Fukuoka, Japan
    J Hypertens 27:2437-43. 2009
    ....
  26. ncbi request reprint Hyperglycemia promotes microinflammation as evaluated by C-reactive protein in the very elderly
    Masayo Fukuhara
    Division of General Internal Medicine, Kyushu Dental College, Kitakyushu, Japan
    Intern Med 46:207-12. 2007
    ..The aim of the present study was to determine whether glycemic control or blood pressure influences the vascular microinflammation as evaluated by CRP levels in the very elderly...
  27. doi request reprint Effects of the superoxide dismutase mimetic tempol on impaired endothelium-dependent and endothelium-independent relaxations in type II diabetic rats
    Hideyuki Oniki
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Exp Hypertens 35:112-9. 2013
    ..These findings suggest that increased oxidative stress may in part account for the impaired endothelium-independent relaxations in diabetes, while it does not play a major role in the impaired EDHF-mediated responses...
  28. ncbi request reprint Improvement of blood pressure control in hypertensive patients with renal diseases
    Yuko Ohta
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 30:295-300. 2007
    ....
  29. doi request reprint Association of body mass index with glomerular filtration rate in Japanese: a cross-sectional study in work-site population
    Yasuo Kansui
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka, Japan
    Clin Exp Hypertens 34:140-4. 2012
    ..Keeping appropriate body weight, in addition to appropriate blood pressure, in young and middle age may be important to prevent renal damage in older age...
  30. doi request reprint Development and validation of a cardiovascular risk prediction model for Japanese: the Hisayama study
    Hisatomi Arima
    Department of Environmental Medicine, Kyushu University, Fukuoka, Japan
    Hypertens Res 32:1119-22. 2009
    ..The risk prediction model would provide a useful guide to estimate absolute risk of cardiovascular disease and to treat individual risk factors...
  31. ncbi request reprint Central and peripheral cardiovascular actions of apelin in conscious rats
    Shuntaro Kagiyama
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Regul Pept 125:55-9. 2005
    ..These results suggest that apelin plays a role in both central and peripheral cardiovascular regulation in conscious rats, and that the cardiovascular effects of apelin are not mediated by the AT1R...
  32. doi request reprint Arterial stiffness and QT interval prolongation in a general population: the Hisayama study
    Daisuke Maebuchi
    Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Hypertens Res 31:1339-45. 2008
    ..0001 for trend). In conclusion, baPWV is independently associated with QT interval prolongation...
  33. doi request reprint Mice heterozygous for the xanthine oxidoreductase gene facilitate lipid accumulation in adipocytes
    Noboru Murakami
    From the Department of Medicine and Clinical Science, Graduate School of Medical Sciences N M, T O, Y K, K G, H N, Y H, K M, T K, Division of Neurofunctional Genomics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation Y N, and Research Center for Nucleotide Pool Y N, Kyushu University, Fukuoka, Japan
    Arterioscler Thromb Vasc Biol 34:44-51. 2014
    ..The aim of this study was to examine the role of XOR in adipose tissue using XOR genetically modified mice...
  34. doi request reprint Upregulation of endothelium-derived hyperpolarizing factor compensates for the loss of nitric oxide in mesenteric arteries of Dahl salt-sensitive hypertensive rats
    Kenichi Goto
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Hypertens Res 35:849-54. 2012
    ..As the overall relaxation in response to ACh did not differ between the groups, the upregulation of EDHF appears to compensate for the loss of NO in the mesenteric arteries of DS-H...
  35. doi request reprint Impact of lower range of prehypertension on cardiovascular events in a general population: the Hisayama Study
    Masayo Fukuhara
    Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Hypertens 30:893-900. 2012
    ..The objective of the present analysis was to examine the impact of prehypertension and its population-attributable fraction for development of cardiovascular events in a general Japanese population...
  36. doi request reprint Chronic kidney disease increases cardiovascular mortality in 80-year-old subjects in Japan
    Shuntaro Kagiyama
    Division of General Internal Medicine, Department of Health Promotion, Science of Health Improvement, Kyushu Dental College, 2 6 1 Manazuru, Kokurakita ku, Kitakyushu 803 8580, Japan
    Hypertens Res 31:2053-8. 2008
    ..Hypertens Res 2008; 31: 2053-2058)...
  37. doi request reprint Association between blood pressure and mortality in 80-year-old subjects from a population-based prospective study in Japan
    Shuntaro Kagiyama
    Division of General Internal Medicine, Department of Health Promotion, Science of Health Improvement, Kyushu Dental College, Kitakyushu, Japan
    Hypertens Res 31:265-70. 2008
    ..However, our results did suggest that high SBP increases the risk of mortality in patients with cardiovascular diseases and/or taking antihypertensive medication...
  38. ncbi request reprint Role of ERK and Rho kinase pathways in central pressor action of urotensin II
    Yingzi Lin
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Hypertens 22:983-8. 2004
    ..It has been shown that central urotensin II acts on the central nervous system to increase arterial pressure in conscious rats...
  39. ncbi request reprint Central cardiovascular action of urotensin II in conscious rats
    Yingzi Lin
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Hypertens 21:159-65. 2003
    ..To examine the central cardiovascular action of urotensin II in conscious rats...
  40. ncbi request reprint Central cardiovascular action of urotensin II in spontaneously hypertensive rats
    Yingzi Lin
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 26:839-45. 2003
    ..These results suggest that central urotensin II may play a role in the pathogenesis of hypertension in SHR. Since GPR 14 was expressed in the glial cells of the brain, urotensin II may act as a neuromodulator to regulate blood pressure...
  41. doi request reprint Role of Rho kinase and oxidative stress in cardiac fibrosis induced by aldosterone and salt in angiotensin type 1a receptor knockout mice
    Shuntaro Kagiyama
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Regul Pept 160:133-9. 2010
    ..These results suggested that the Rho kinase pathway was activated to induce cardiac fibrosis by Ald-NaCl via MR in AT1aR-KOs. A Rho kinase inhibitor as well as eplerenone might be useful for cardiac damage by Ald-NaCl...
  42. ncbi request reprint Association of dental status with blood pressure and heart rate in 80-year-old Japanese subjects
    Kiyoshi Matsumura
    Department of Internal Medicine, Kyushi Dental College, Kitakyushu, Japan
    Jpn Heart J 44:943-51. 2003
    ..These results are the first to show a close inverse relationship between the number of teeth and heart rate in octogenariars, although the underlying mechanisms have not been determined...
  43. doi request reprint White-coat and masked hypertension are associated with carotid atherosclerosis in a general population: the Hisayama study
    Masayo Fukuhara
    Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Stroke 44:1512-7. 2013
    ..The objective of this study was to investigate the associations of WCHT, MHT, and SHT with carotid atherosclerosis in a general population...
  44. doi request reprint Facilitation of sympathetic neurotransmission by phosphatidylinositol-4,5-bisphosphate-dependent regulation of KCNQ channels in rat mesenteric arteries
    Yasuo Kansui
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 35:909-16. 2012
    ....
  45. ncbi request reprint Association of serum uric acid with blood pressure in Japanese men. Cross-sectional study in work-site group
    Yasuo Kansui
    Department of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan
    Circ J 75:2827-32. 2011
    ..It has been reported that elevated levels of serum uric acid are related to hypertension and cardiovascular disease. Recent studies, however, have found little association between hyperuricemia and hypertension...
  46. doi request reprint Correlation between increased urinary sodium excretion and decreased left ventricular diastolic function in patients with type 2 diabetes mellitus
    Shuntaro Kagiyama
    Division of General Internal Medicine, Department of Health Promotion, Science of Health Improvement, Kyushu Dental College, Kitakyushu, Japan
    Clin Cardiol 32:569-74. 2009
    ..Diabetes mellitus (DM) is an established risk factor for heart failure. However, little is known about the relationship between cardiac function and urinary sodium excretion (U-Na) in patients with DM...
  47. ncbi request reprint Renal and carotid vascular resistance assessed with Doppler sonography
    Yuko Ohta
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Clin Ultrasound 36:85-90. 2008
    ..The present study was designed to evaluate the relationship between renal and carotid artery RI and to compare their relative risk factors for an increase in RI...
  48. ncbi request reprint Increased renal resistive index in atherosclerosis and diabetic nephropathy assessed by Doppler sonography
    Yuko Ohta
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Hypertens 23:1905-11. 2005
    ..We evaluated the relationship between these indices and pulse wave velocity (PWV), a measure of arterial stiffness, which reflects atherosclerosis, and determined whether renal RI and PI differ depending on the underlying renal disease...
  49. pmc Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules
    Toshio Ohtsubo
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, Japan
    Hypertension 54:868-76. 2009
    ....
  50. ncbi request reprint Aldosterone-and-salt-induced cardiac fibrosis is independent from angiotensin II type 1a receptor signaling in mice
    Shuntaro Kagiyama
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 30:979-89. 2007
    ....
  51. ncbi request reprint Accumulation of 8-oxo-deoxyguanosine in cardiovascular tissues with the development of hypertension
    Toshio Ohtsubo
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    DNA Repair (Amst) 6:760-9. 2007
    ..We thus suggest that MTH1 may protect EC in the aorta from the oxidative damage increased by hypertension...
  52. doi request reprint Perioperative blood pressure variability in the treated hypertensive patients
    Kanako Kiyohara
    Division of Hypertension, Clinical Research Institute, National Kyushu Medical Center, Fukuoka, Japan
    Clin Exp Hypertens 35:291-4. 2013
    ..Our findings suggest that 24-hour BP decreases after gastrectomy. Patients taking ACE inhibitors or ARBs may need careful monitoring to prevent excessive BP fall...
  53. ncbi request reprint [Modulation of sympathetic activity by ghrelin in the central nervous system]
    Kiyoshi Matsumura
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
    Nihon Rinsho 62:373-6. 2004
  54. doi request reprint Salt intake in 3-year-old Japanese children
    Yuki Morinaga
    Division of Hypertension, Clinical Research Institute, National Kyushu Medical Center, Fukuoka, Japan
    Hypertens Res 34:836-9. 2011
    ..These results suggest that excess salt intake occurs in a significant number of 3-year-old Japanese children. The presence of older siblings and dietary habits of eating snacks or fruits influence their sodium and potassium intake...
  55. doi request reprint Cilostamide produces hyperpolarization associated with K(ATP) channel activation, but does not augment endothelium-derived hyperpolarization in rat mesenteric arteries
    Yasuo Kansui
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Exp Pharmacol Physiol 36:729-33. 2009
    ..5. The findings of the present study suggest that cilostamide produces hyperpolarization by activating K(ATP) channels, presumably by increasing cAMP. However, cilostamide alone may not directly affect EDH...
  56. doi request reprint High-sensitivity C-reactive protein and coronary heart disease in a general population of Japanese: the Hisayama study
    Hisatomi Arima
    Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Arterioscler Thromb Vasc Biol 28:1385-91. 2008
    ..The purpose of this study was to investigate the effects of high-sensitivity C-reactive protein (hs-CRP) on the risks of coronary heart disease (CHD) in a general population of Japanese...
  57. ncbi request reprint Prediction of cognitive function by arterial stiffness in the very elderly
    Masayo Fukuhara
    Division of General Internal Medicine, Department of Health Promotion, Science of Health Improvement, Kyushu Dental College, Fukuoka, Japan
    Circ J 70:756-61. 2006
    ..Cognitive function is impaired in elderly subjects, so the aim of the present study was to determine the role of arterial stiffness on cognitive function...
  58. pmc Differential effects of organic nitrates on arterial diameter among healthy Japanese participants with different mitochondrial aldehyde dehydrogenase 2 genotypes: randomised crossover trial
    Satoko Sakata
    Department of Medicine and Clinical Science, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    BMJ Open 1:e000133. 2011
    ..GTN dilated the artery more quickly than ISDN in *1/*1 and *1/*2, but not in *2/*2. Trial registration number UMIN000001492 (UMIN-CTR database)...
  59. ncbi request reprint GRAFT infection of thoracic aorta due to group C beta-hemolytic streptococcus--a case report
    Hisatomi Arima
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Angiology 56:237-41. 2005
    ..A rare case of graft infection of thoracic aorta in terms of causative organism, long period from graft replacement to graft infection, and site of infection is presented and discussed...
  60. pmc Direct pyrogenic input from prostaglandin EP3 receptor-expressing preoptic neurons to the dorsomedial hypothalamus
    Yoshiko Nakamura
    Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Eur J Neurosci 22:3137-46. 2005
    ..These results suggest that a direct projection of EP3 receptor-expressing POA neurons to the DMH/DH region mediates febrile responses via a GABAergic mechanism...
  61. ncbi request reprint Neurons of the rat preoptic area and the raphe pallidus nucleus innervating the brown adipose tissue express the prostaglandin E receptor subtype EP3
    Kyoko Yoshida
    Veterinary Physiology, and Institute of Virology, Justus Liebig University Giessen, Frankfurter Strasse 100 and 107, D 35392 Giessen, Germany
    Eur J Neurosci 18:1848-60. 2003
    ....
  62. ncbi request reprint Ionic basis of cold receptors acting as thermostats
    Makoto Okazawa
    Division of Biological Information, Department of Intelligence Science and Technology, Graduate School of Informatics, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 22:3994-4001. 2002
    ..Because these thermal properties were consistent with that in cold fibers, we conclude that the same cold receptors exist at nerve endings and generate afferent impulses for cold sensation and heat-gain behaviors in response to cold...
  63. ncbi request reprint Immunohistochemical evidence of functional leptin receptor expression in neuronal and endothelial cells of the rat brain
    Jörg Mütze
    Veterinary Physiology, Justus Liebig University Giessen, Germany
    Neurosci Lett 394:105-10. 2006
    ..In conclusion, neurons and non-neuronal brain cells, e.g., endothelial or choroid plexus cells, seem to express functional leptin receptors and might thereby mediate leptin-dependent functions in the rat brain...
  64. pmc Cellular and molecular bases of the initiation of fever
    Alexandre A Steiner
    Systemic Inflammation Laboratory, Trauma Research, St Joseph s Hospital and Medical Center, Phoenix, Arizona, United States of America
    PLoS Biol 4:e284. 2006
    ..Whether PGE2 produced at the level of the blood-brain barrier also contributes to the development of the first phase remains to be clarified...
  65. ncbi request reprint The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area
    Kazuhiro Nakamura
    Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Department of Intelligence Science and Technology, Japan Science and Technology, Sakyo ku, Kyoto 606 8502, Japan
    J Neurosci 22:4600-10. 2002
    ..Our results demonstrate that the rRPa, which has never been associated with the fever mechanism, mediates the pyrogenic neurotransmission from the POA to the peripheral sympathetic effectors contributing to fever development...
  66. ncbi request reprint [Hypertension complicated with cerebrovascular disorders]
    Kiyoshi Matsumura
    Nihon Naika Gakkai Zasshi 96:73-8. 2007
  67. ncbi request reprint Up-regulated neuronal COX-2 expression after cortical spreading depression is involved in non-REM sleep induction in rats
    Yilong Cui
    Molecular Imaging Research Program, Institute of Physical and Chemical Research RIKEN, Kobe, Hyogo, Japan
    J Neurosci Res 86:929-36. 2008
    ..A specific inhibitor of COX-2 completely arrested the increase in NREM sleep. These results indicate that up-regulated neuronal COX-2 would be involved in aberrant brain excitation-induced NREM sleep via production of PGs...
  68. ncbi request reprint Cyclooxygenase-2 is induced in the endothelial cells throughout the central nervous system during carrageenan-induced hind paw inflammation; its possible role in hyperalgesia
    Takae Ibuki
    Anesthesiology, Graduate School of Medical Science and Radiology, Graduate School of Medical Science Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Neurochem 86:318-28. 2003
    ....
  69. ncbi request reprint Sympathetic premotor neurons mediating thermoregulatory functions
    Kazuhiro Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8501, Japan
    Neurosci Res 51:1-8. 2005
    ..The VGLUT3-expressing premotor neurons would mediate thermoregulation including fever induction, and could be also involved in the control of energy metabolism...
  70. ncbi request reprint Signaling the brain in inflammation: the role of endothelial cells
    Kiyoshi Matsumura
    Department of Intelligence Science and Technology, Graduate School of Informatics, Kyoto University, Kyoto 606 8501, Japan
    Front Biosci 9:2819-26. 2004
    ..In this review, we highlight the significance of the endothelial mechanism in immune-brain signaling mediated by PGE2, but discuss also the possible influence of other mechanisms on brain PGE2 elevation...
  71. ncbi request reprint Identification of sympathetic premotor neurons in medullary raphe regions mediating fever and other thermoregulatory functions
    Kazuhiro Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 24:5370-80. 2004
    ....