Research Topics
Genomes and GenesSpecies | T MatsumotoSummaryAffiliation: Kyushu University Country: Japan Publications
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Publications
Long-term clinical outcome of gastric MALT lymphoma after eradication of Helicobacter pylori: a multicentre cohort follow-up study of 420 patients in JapanShotaro Nakamura
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Gut 61:507-13. 2012..A multicentre cohort follow-up study of a large number of patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma was conducted to elucidate the long-term outcome of the disease after Helicobacter pylori eradication...
Primary gastrointestinal lymphoma in Japan: a clinicopathologic analysis of 455 patients with special reference to its time trendsShotaro Nakamura
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Cancer 97:2462-73. 2003..This study aimed to elucidate the clinicopathologic features of this disease and the influence of therapeutic modalities on the prognosis in Japanese patients..
Translocations involving the immunoglobulin heavy chain gene locus predict better survival in gastric diffuse large B-cell lymphomaShotaro Nakamura
Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
Clin Cancer Res 14:3002-10. 2008....
Impact of Helicobacter pylori infection and mucosal atrophy on gastric lesions in patients with familial adenomatous polyposisS Nakamura
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Gut 51:485-9. 2002..The role of Helicobacter pylori and atrophic gastritis in the pathogenesis of gastric lesions in familial adenomatous polyposis (FAP) has not been clarified...
Predictive value of endoscopic ultrasonography for regression of gastric low grade and high grade MALT lymphomas after eradication of Helicobacter pyloriS Nakamura
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Gut 48:454-60. 2001..While a close association between gastric mucosa associated lymphoid tissue (MALT) lymphoma and Helicobacter pylori infection has been established, there are still cases which do not respond to H pylori eradication...
Long-term clinical outcome of Helicobacter pylori eradication for gastric mucosa-associated lymphoid tissue lymphoma with a reference to second-line treatmentShotaro Nakamura
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
Cancer 104:532-40. 2005....
Endoscopic findings of enteropathy-type T-cell lymphomaS Yanai
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 39:E339-40. 2007
Role of bacterial capsule in local and systemic inflammatory responses of mice during pulmonary infection with Klebsiella pneumoniaeK Yoshida
Second Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan
J Med Microbiol 49:1003-10. 2000..These results suggest that K. pneumoniae capsule may suppress the host immunological responses,thus allowing the bacteria to grow, causing pneumonia, septicaemia and death...
Changes in Helicobacter pylori status in patients with rheumatoid arthritis under non-steroidal anti-inflammatory drugsT Moriyama
Dept of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Scand J Gastroenterol 39:111-8. 2004..The role of Helicobacter pylori infection in rheumatoid arthritis (RA) patients during treatment with non-steroidal anti-inflammatory drugs (NSAID) is still unclear...
Intraoperative enteroscopy detects more lesions but is not predictive of postoperative recurrence in Crohn's diseaseM Esaki
Department of Internal Medicine II, Kyushu University Hospital, Maidashi 3 1 1, Fukuoka 812 8582, Japan
Surg Endosc 15:455-9. 2001..The aim of this investigation was to elucidate the clinical value of intraoperative enteroscopy (IOE) for Crohn's disease, and to determine the value of IOE in predicting recurrent disease...
Mucosal proinflammatory cytokine and chemokine expression of gastroduodenal lesions in Crohn's diseaseT Moriyama
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
Aliment Pharmacol Ther 21:85-91. 2005..The stomach and the duodenum are frequent sites of involvement by diminutive lesions in Crohn's disease (CD)...
Endoscopic features of intestinal follicular lymphoma: the value of double-balloon enteroscopyS Nakamura
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 39:E26-7. 2007
Enhanced expression of osteopontin in human diabetic artery and analysis of its functional role in accelerated atherogenesisM Takemoto
Second Department of Internal Medicine, School of Medicine, Chiba University, Chiba, Japan
Arterioscler Thromb Vasc Biol 20:624-8. 2000..Taken together, our present results raise a possibility that OPN plays a role in the development of diabetic vascular complications...
Chromosomal translocation t(11;18)(q21;q21) in gastrointestinal mucosa associated lymphoid tissue lymphomaS Nakamura
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
J Clin Pathol 56:36-42. 2003..To evaluate the chromosomal translocation t(11;18)(q21;q21) in gastrointestinal lymphomas...
Cap polyposis of the colon and rectum: an analysis of endoscopic findingsM Esaki
Dept of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 33:262-6. 2001..Because of the rarity of cap polyposis of the colon and rectum, the endoscopic features of this condition have not been specified to date. The aim of this study is to characterize the endoscopic features of cap polyposis...
Platelet-derived growth factor activates p38 mitogen-activated protein kinase through a Ras-dependent pathway that is important for actin reorganization and cell migrationT Matsumoto
Second Department of Internal Medicine, Chiba University School of Medicine, 1 8 1 Inohana, Chuou ku, Chiba 260 0856, Japan
J Biol Chem 274:13954-60. 1999..Taken together, our present study proposes the existence of a Ras-dependent pathway for the activation of p38, which is important for cell motility responses elicited by PDGF stimulation...
Significance of vitamin D receptor gene polymorphism for risk and disease severity of prostate cancer and benign prostatic hyperplasia in JapaneseT Hamasaki
Department of of Urology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
Urol Int 68:226-31. 2002....
Impact of Helicobacter pylori infection on gastric cancer incidence in a general Japanese population: the Hisayama studyH Yamagata
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
Arch Intern Med 160:1962-8. 2000..The purpose of this study is to examine the impact of H pylori infection on gastric cancer occurrence in a general Japanese population (Hisayama, Japan) stratified according to sex, using a prospective study design...
Is endoscopic ultrasonography indispensable in assessing the appropriateness of endoscopic resection for gastric cancer?K Hizawa
Dept of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 34:973-8. 2002..The aim of the present study was to investigate the accuracy of pretherapeutic staging techniques for assessing the appropriateness of endoscopic resection...
Capsule endoscopy findings in intestinal follicular lymphomaM Esaki
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 39:E86-7. 2007
Enhanced chemiluminescence response of polymorphonuclear leukocytes by new quinolone antimicrobialsS Kubo
Department of Urology, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Chemotherapy 40:333-6. 1994..Other antimicrobial agents, however, inhibited CL response. This suggested that fleroxacin and ofloxacin were more efficient in the treatment of bacterial infections with respect to the interaction between antimicrobials and PMNs...
Clinical significance of LAMB3 and COL7A1 mRNA in esophageal squamous cell carcinomaY Kita
Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Tsurumihara, Beppu, Japan
Eur J Surg Oncol 35:52-8. 2009..They constitute the major components of the basement membrane zone. The aim of the current study was to clarify the clinical significance of LAMB3 and COL7A1 mRNA expression in esophageal squamous cell carcinoma (ESC)...
Small invasive colonic cancer occurring in a hyperplastic polypT Kudo
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
Endoscopy 36:825-8. 2004..This case was considered to be important because it raises the possibility that nonpolypoid cancer can develop from a hyperplastic polyp...
Serrated adenoma in familial adenomatous polyposis: relation to germline APC gene mutationT Matsumoto
Department of Endoscopic Diagnostics and Therapeutics, Kyushu University Hospital, Fukuoka, Japan
Gut 50:402-4. 2002..Serrated adenoma is a precursor of colorectal cancer...
The immuno-inflammatory mechanism for tissue injury in inflammatory bowel disease and Helicobacter pylori-infected chronic active gastritis. Roles of the mucosal immune systemH Nagura
Department of Pathology, Tohoku University Graduate School of Medical Science, Sendai, Japan
Digestion 63:12-21. 2001..pylori infection, respectively...
Risk factors for local recurrence of superficial esophageal cancer after treatment by endoscopic mucosal resectionM Esaki
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 39:41-5. 2007..The aim of this study was to elucidate the risk factors for local recurrence after endoscopic mucosal resection (EMR) treatment for superficial esophageal cancer (SEC)...
Diminutive gastrointestinal lesions in cholesterol crystal embolizationM Hirahashi
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 37:408. 2005
Autofluorescence imaging colonoscopy for the detection of dysplastic lesions in ulcerative colitis: a pilot studyT Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Colorectal Dis 12:e291-7. 2010..The aim of this investigation was to examine whether AFI colonoscopy can identify dysplasia in ulcerative colitis...
Fleroxacin enhancement of superoxide production by polymorphonuclear leukocytes: the role of protein kinasesT Matsumoto
Department of Urology, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Chemotherapy 42:280-5. 1996..These results suggest that FLRX augments superoxide production by PMNs through enhancing the activities of phosphorylation by PKC or TK within the signal transduction pathway in PMNs...
A case of multicentric gastric carcinoids without hypergastrinemiaT Moriyama
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
Endoscopy 35:86-8. 2003..No mutations of the MEN1 gene were found on genomic DNA analysis. Despite the multiplicity of carcinoid tumors, we diagnosed type 3 gastric carcinoid in this patient...
CCR4 is an up-regulated chemokine receptor of peripheral blood memory CD4+ T cells in Crohn's diseaseY Jo
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Clin Exp Immunol 132:332-8. 2003..Enhancement of CCR4 and suppression of CCR5 and CXCR3 seem to be the characteristic chemokine receptor profile in peripheral blood memory T cells of CD...
Clinical and endoscopic features of nonsteroidal anti-inflammatory drug-induced colonic ulcerationsK Kurahara
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Am J Gastroenterol 96:473-80. 2001..CONCLUSIONS: NSAID-induced colonic ulceration may occur more frequently than previously recognized. Frank ulcerations, rather than stricture formation, seem to be the typical colonoscopic signs of NSAID-induced colonic ulceration...
Gastric inflammatory polyposis after long-term intermittent use of nonsteroidal anti-inflammatory drugs and histamine2-receptor antagonistsK Hizawa
Dept. of Internal Medicine, Kyushu Central Hospital, Fukuoka, Japan
Endoscopy 37:685. 2005
Accuracy of radiographic assessment for the diagnosis of invasion depth in small invasive colorectal cancerT Matsumoto
Departments of Medicine and Clinical Science and Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan
Br J Radiol 76:611-6. 2003..023) were significantly higher in CRCs <or=10 mm than in those >10 mm. These findings suggest that barium radiography is a procedure which can give useful information in prediction of invasion depth in CRCs <or=10 mm in size...
Gastroprotective and vasodilatory effects of epidermal growth factor: the role of sensory afferent neuronsY Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
Am J Physiol Gastrointest Liver Physiol 280:G897-903. 2001..These findings suggest that EGF plays a protective role against ethanol-induced gastric mucosal injury, possibly by dilating the gastric mucosal arterioles via capsaicin-sensitive afferent neurons involving CGRP and NO mechanisms...
The significance of cytomegalovirus infection over the clinical course of adult T-cell leukemia/lymphomaH Fujiwara
First Department of Internal Medicine, Center for Chronic Viral Diseases, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
Microbiol Immunol 45:97-100. 2001..Therefore, it appears likely that patients with CMV infections on admission were in an immunosuppressive state due to aggressive ATL activity...
Inflammatory myoglandular colorectal polyps: a case series of nine patientsT Moriyama
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 35:363-5. 2003..Inflammatory myoglandular polyp appears to be a distinctive clinical entity, with a unique appearance on colonoscopy...
Multiple microcarcinoids in a patient with long standing ulcerative colitisT Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
J Clin Pathol 56:963-5. 2003..Carcinoids may be more common than previously thought, and they may be a reactive phenomenon to a variety of factors in ulcerative colitis...
Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposisR Yanaru-Fujisawa
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Clin Genet 73:545-53. 2008..Homozygous MUTYH mutation accounts for approximately 10% of Japanese patients with adenomatous polyposis. G272E may be one of the mutations specific to patients with adenomatous polyposis in East Asia...
Comparison of capsule endoscopy and enteroscopy with the double-balloon method in patients with obscure bleeding and polyposisT Matsumoto
Dept of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
Endoscopy 37:827-32. 2005..Video capsule endoscopy and double-balloon enteroscopy (DBE) are novel methods of enteroscopy. The aim of this investigation was to compare the value of CE and DBE in the diagnosis of small-intestinal pathology...
[A nation-wide surveillance of pathogen in elderly patients with urinary tract infections. 2nd Report: Sensitivities of pathogen for oral antibacterial agents]J Kumazawa
Department of Urology, Faculty of Medicine, Kyushu University
Kansenshogaku Zasshi 69:797-810. 1995..Regardless of the size of the clinic or hospital, Fluoroquinolones are more suitable for the treatment of elderly patients with UTIs than cephems...
Effect of diet on changes in small intestinal blood flow following intracolonic administration of indomethacin to ratsC Yamamoto
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Japan
Dig Dis Sci 46:200-7. 2001..Our findings suggest that solid components of diet increase basal SIBF and decrease SIBF following indomethacin administration...
Endoscopic ultrasonography in rectal carcinoid tumors: contribution to selection of therapyT Matsumoto
Second Department of Internal Medicine, Kyushu University, Fukuoka, Japan
Gastrointest Endosc 37:539-42. 1991..We believe that even though EUS is not efficacious in cases of very small carcinoid tumors of the rectum, it can provide clinically important information in choosing therapy...
Sulfamethizole absorption test for the assessment of gastric emptying. Comparison with scintigraphic methodK Hirakawa
Second Dept of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Scand J Gastroenterol 30:133-8. 1995....
Non-specific multiple ulcers of the small intestine unrelated to non-steroidal anti-inflammatory drugsT Matsumoto
Department of Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
J Clin Pathol 57:1145-50. 2004..Non-steroidal anti-inflammatory drug (NSAID) enteropathy is a cause of chronic blood and protein loss from the intestine. The aim of this investigation was to compare NSAID enteropathy with enteropathy not related to chronic NSAID use...
Clinicopathological and biological significance of mitotic centromere-associated kinesin overexpression in human gastric cancerY Nakamura
Department of Surgery and Molecular Oncology, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumibaru, Beppu 874 0838, Japan
Br J Cancer 97:543-9. 2007..These characteristics may be due in part to the increased proliferative and migratory ability of cells expressing MCAK...
Helicobacter pylori infection in rheumatoid arthritis: effect of drugs on prevalence and correlation with gastroduodenal lesionsN Ishikawa
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan
Rheumatology (Oxford) 41:72-7. 2002..pylori infection in RA patients. Sulphasalazine may be protective against H. pylori infection...
The value of double-contrast study of the small intestine in immunoproliferative small intestinal diseaseT Matsumoto
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Gastrointest Radiol 15:159-63. 1990..Double-contrast studies are one of the most important examinations in the diagnosis of this disorder...
Endosonographic features of Brunner's gland hamartomas which were subsequently resected endoscopicallyK Hizawa
Dept of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 34:956-8. 2002..Brunner's gland hamartomas are uncommon duodenal submucosal tumors. We aim to describe their morphological characteristics, with particular attention to the endosonographic features...
Differences in p53 and cadherin-catenin complex expression between histological subtypes in diffusely infiltrating gastric carcinomaT Kozuki
Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Histopathology 41:56-64. 2002..CONCLUSIONS: These two subtypes seem to be different in nature and biological behaviour. The preservation of adhesion molecules in mixed type may be associated with higher incidence of lymphatic permeation and lymph node metastasis...
Reduced clinical efficacy of pazufloxacin against gonorrhea due to high prevalence of quinolone-resistant isolates with the GyrA mutation. The Pazufloxacin STD GroupM Tanaka
Department of Urology, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Antimicrob Agents Chemother 42:579-82. 1998..The results obtained in this study suggest that a high prevalence of fluoroquinolone-resistant gonococcal isolates with the Ser-91-to-Phe mutation in GyrA reduced the efficacy of pazufloxacin as treatment for gonococcal urethritis...
Pyogenic granuloma of the esophagus treated by endoscopic removalN Okada
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Endoscopy 35:375. 2003
Quantitative MRI findings and cognitive impairment among community dwelling elderly subjectsH Koga
Department of Neuropsychiatry, Faculty of Medicine, Kyushu University Hospital, Maidashi, Fukuoka 812 8582, Japan
J Neurol Neurosurg Psychiatry 72:737-41. 2002....
The efficacy of oral beraprost sodium, a prostaglandin I2 analogue, for treating intermittent claudication in patients with arteriosclerosis obliteransT Matsumoto
Department of Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Int Angiol 29:49-54. 2010..Furthermore, this study aimed to assess the mechanism of action of beraprost sodium via blood sampling and measurements of flow-mediated vasodilatation before and after treatment...
Possible role of telomerase activation in the multistep tumor progression of periampullary lesions in patients with familial adenomatous polyposisI Mizumoto
Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Am J Gastroenterol 96:1261-5. 2001..CONCLUSIONS: Telomerase is activated even in normal mucosa of FAP patients, and the intensities of telomerase may reflect the malignant potential of periampullary neoplasms...
Induction of interleukin-10 and down-regulation of cytokine production by Klebsiella pneumoniae capsule in mice with pulmonary infectionK Yoshida
Second Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan
J Med Microbiol 50:456-61. 2001..The results suggest that the capsule of K. pneumoniae may induce IL-10 production at the site of infection and, thereafter, these high IL-10 levels may serve to down-regulate the expression of pro-inflammatory cytokines...
Diagnosis of retrovesical ectopic and hyperplastic prostate tissue by transrectal needle biopsyT Hamasaki
Department of Urology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
Urol Int 66:171-3. 2001..The tumor was histologically confirmed to be a benign prostatic hyperplasia. This is the 3rd case of retrovesical ectopic prostatic tissue which was diagnosed by transrectal needle biopsy...
Incidence and prognosis of gastric cancer in a population-based cohort survey: the Hisayama studyK Tanaka
Dept of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Scand J Gastroenterol 39:459-63. 2004....
Cytokine production of peripheral blood mononuclear cells in a dermatophytosis patient in response to stimulation with trichophytinT Koga
Department of Dermatology, Faculty of Medicine, Kyushu University, Fukuoka, Japan
J Dermatol 20:441-3. 1993..These findings indicate that this patient has peripheral T-lymphocytes that produced IFN-gamma, IL-2 and GM-CSF, which may play roles in the development of delayed-type hypersensitivity (DTH) reaction in the skin...
[Long-term survival of hormone-refractory prostate cancer: a case report]N Fujimoto
Department of Urology, School of Medicine, University of Occupational and Environmental Health, Japan, Yahatanishi-ku, Kitakyushu 807-8555, Japan
J UOEH 23:51-8. 2001..This case indicates that alteration of antiandrogens or oral chemotherapy may be useful in some cases with hormone-refractory prostate cancer...
Contribution of neutrophils to lipopolysaccharide-induced tumor necrosis factor production and mortality in a carrageenan-pretreated mouse modelT Matsumoto
Department of Anesthesiology, School of Medicine, University of Occupational and Environmental Health, Japan, Fukuoka, Japan
FEMS Immunol Med Microbiol 17:171-8. 1997..We suggest that neutrophils are the major cells to produce TNF-alpha and to determine mouse mortality after LPS challenge in the mouse CAR model...
Primary biliary cirrhosis associated with ulcerative colitisM Nakayama
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
Fukuoka Igaku Zasshi 92:354-9. 2001..This is the 12th report of a patient presenting with the combination of primary biliary cirrhosis and ulcerative colitis. The potential autoimmune relationships on the basis of these conditions are discussed...
Genetic identification of bilateral primary or metastatic nonpapillary renal cell carcinomaH Kume
Departments of Urology and Molecular Pathology, Faculty of Medicine, University of Tokyo, Japan
BJU Int 86:208-12. 2000....
Fatty replacement of the pancreatic body and tail associated with leiomyosarcoma of the pancreatic headM Shimizu
Department of Pathology, Kawasaki Medical School, Kurashiki, Japan
Pathol Int 47:633-6. 1997..Clinicopathological features as well as differential diagnoses are described with a review of the literature on both leiomyosarcoma and fatty replacement of the pancreas. A possible correlation between the two lesions is also discussed...
Inflammatory bowel disease-like colitis in glycogen storage disease type 1bT Yamaguchi
Department of Pediatric, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Inflamm Bowel Dis 7:128-32. 2001..These findings suggest that IBD-like colitis is a grave complication of GSD-1b and that recurrent enteric infections due to neutrophil deficiency may contribute to the development of this bowel disease...
Enhanced expression of osteopontin by high glucose. Involvement of osteopontin in diabetic macroangiopathyM Takemoto
Second Department of Internal Medicine, School of Medicine, Chiba University, Japan
Ann N Y Acad Sci 902:357-63. 2000..Our results suggest that osteopontin could play a role in the development of diabetic vascular complications...
Clinical and pathological significance of vitamin D receptor gene polymorphism for prostate cancer which is associated with a higher mortality in JapaneseT Hamasaki
Department of Urology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
Endocr J 48:543-9. 2001..002). These data demonstrate that VDR genotype plays an important role in determining the risk of more clinically advanced and pathologically aggressive prostate cancer which is associated with a higher mortality rate in Japanese men...
[A nation-wide surveillance of pathogen in elderly patients with urinary tract infections. 1st Report: Distribution of pathogen]J Kumazawa
Department of Urology, Faculty of Medicine, Kyushu University
Kansenshogaku Zasshi 69:790-6. 1995..Regardless of the size of the clinic or hospital, when treating elderly patients, with unsatisfactory results in initial treatment and with less subjective symptoms the physician must bear this in mind...
Association between birthweight and body mass index at 3 years of ageT Tanaka
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
Pediatr Int 43:641-6. 2001..0001 and P=0.0095, respectively). CONCLUSIONS: Infants with higher birthweight and/or greater weight gain during the first month of life may have a risk of being overweight at 3 years of age...
Acute effects of oral glucose loading on the renin-angiotensin-aldosterone system in patients with chronic renal diseaseJ Uemasu
Second Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan
Horm Metab Res 25:110-3. 1993..These data demonstrated that the glucose-induced renin-angiotensin-aldosterone system in patients with chronic renal disease differed from that in healthy subjects...
Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarctionA Tsuchida
Second Department of Internal Medicine, Sapporo Medical University, School of Medicine, Japan
Basic Res Cardiol 96:446-53. 2001..The present study was designed to assess the relationship between the timing of a mitoK(ATP) channel opener, diazoxide, and its infarct size-limiting effect...
Non-penetrating vascular clips anastomosis inhibited intimal thickening under poor runoff conditions in canine autogenous vein graftsK Komori
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812, Japan
Eur J Vasc Endovasc Surg 21:241-7. 2001....
Effects of cyclosporin A on refractory B-cell chronic lymphocytic leukemiaK Nishii
Second Department of Internal Medicine, Mie University School of Medicine, Japan
Int J Hematol 71:59-65. 2000..Because in vitro experiments cannot explain this phenomenon of Cs-A increasing leukemic cells (not only B-CLL cells but also T cells), care should be exercised in the clinical use of Cs-A in B-CLL patients...
Impact of Phospholipase A2 group IIa gene polymorphism on phenotypic features of patients with familial adenomatous polyposisRitsuko Yanaru-Fujisawa
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka, Japan
Dis Colon Rectum 50:223-31. 2007..This investigation was designed to elucidate possible association between phospholipase A2 Group IIa polymorphism and phenotypes of patients with familial adenomatous polyposis...
Autofluorescence imaging colonoscopy for the diagnosis of dysplasia in ulcerative colitisTakayuki Matsumoto
Inflamm Bowel Dis 13:640-1. 2007
Factors affecting recurrence in patients with Crohn's disease under nutritional therapyMotohiro Esaki
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
Dis Colon Rectum 49:S68-74. 2006..This retrospective study was designed to determine risk factors for recurrence of Crohn's disease under enteral nutrition...
Intramucosal gastric adenocarcinoma of poorly differentiated type in the young is characterized by Helicobacter pylori infection and antral lymphoid hyperplasiaMinako Hirahashi
Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Mod Pathol 20:29-34. 2007..pylori infection with antral chronic inflammation with lymphoid-follicle hyperplasia, regardless of the existence of intestinal metaplasia within the background gastric mucosa...
[Cytokine targetting therapy for inflammatory bowel diseases]Takayuki Matsumoto
Nippon Naika Gakkai Zasshi 95:1781-6. 2006
Endoscopic features of chronic nonspecific multiple ulcers of the small intestine: comparison with nonsteroidal anti-inflammatory drug-induced enteropathyTakayuki Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka, 812 8582, Japan
Dig Dis Sci 51:1357-63. 2006..In contrast, all four patients with CNSU had active ulcer. These findings suggest that in patients with persistent GI bleeding and enteroscopically active small intestinal ulcers, CNSU, as well as NSAID-enteropathy, should be considered...
Hypermethylation of p14 (ARF) may be predictive of colitic cancer in patients with ulcerative colitisTomohiko Moriyama
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka, Japan
Dis Colon Rectum 50:1384-92. 2007..This study was designed to assess the significance of those genetic or epigenetic alterations for cancer surveillance in ulcerative colitis...
Recombinant human granulocyte colony-stimulating factor reduces colonic epithelial cell apoptosis and ameliorates murine dextran sulfate sodium-induced colitisTetsuji Kudo
Department of Medicine, Graduate School of Medical Sciences, Kyusyu University, Fukuoka, Japan
Scand J Gastroenterol 43:689-97. 2008..Recombinant human granulocyte colony-stimulating factor (rhG-CSF) is a potentially effective therapy for Crohn's disease. The purpose of this study was to test the rhG-CSF in murine dextran sulfate sodium-induced colitis (DSS colitis)...
Gastroduodenitis associated with ulcerative colitisKazutoshi Hori
Department of Endoscopy Center, Hyogo College of Medicine, Nishinomiya, 663 8501, Japan
J Gastroenterol 43:193-201. 2008..The aim of this study was to examine the prevalence and characteristics of gastroduodenitis associated with UC (GDUC)...
Prevalence of non-steroidal anti-inflammatory drug-induced enteropathy determined by double-balloon endoscopy: a Japanese multicenter studyTakayuki Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka
Scand J Gastroenterol 43:490-6. 2008..The aim of this study was to determine the prevalence of NSAIDs enteropathy in subjects indicated for double-balloon endoscopy (DBE)...
Linear mucosal defect may be characteristic of lansoprazole-associated collagenous colitisJunji Umeno
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Gastrointest Endosc 67:1185-91. 2008..Although some cases of collagenous colitis have been induced by lansoprazole (LPZ), the clinicopathologic features of LPZ-associated collagenous colitis have not been elucidated...
Impact of smoking on mortality in 80-year-old Japanese from the general populationKiyoshi Fujisawa
Division of General Internal Medicine, Kyushu Dental College, Kitakyushu, Japan
Gerontology 54:210-6. 2008..It is well known that cigarette smoking is the main health hazard in middle-aged people.However, data regarding smoking and health in old-aged people are limited, especially in the Japanese population...
Therapeutic efficacy of infliximab on patients with short duration of Crohn's disease: a Japanese multicenter surveyTakayuki Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, 812 8582, Japan
Dis Colon Rectum 51:916-23. 2008..This study was designed to evaluate the efficacy of infliximab in patients with Crohn's disease of durations less than one year...
[Nonsteroidal anti-inflammatory drug-induced enteropathy and chronic nonspecific multiple ulcers of the small intestine]Takayuki Matsumoto
Department of Medicine and Clinical Science, Kyushu University
Nihon Rinsho 66:1323-9. 2008..In consideration of widespread use of NSAIDs, a strategy for the prevention of NSAIDs-enteropathy should be examined. Also, much more cases of CNSU should be analyzed to establish the pathophysiology of the disease...
Endoscopic and histological diagnosis on upper gastrointestinal cancer screeningKazuoki Hizawa
Department of Internal Medicine, Kyushu Central Hospital, Fukuoka, Japan
Hepatogastroenterology 54:1725-7. 2007..Screening endoscopy for upper gastrointestinal cancer has come into wide use in Japan. We aim to clarify the limitation of its endoscopic diagnosis and contribution of histological biopsy on routine endoscopy...
Is small-bowel radiography necessary before double-balloon endoscopy?Takayuki Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
AJR Am J Roentgenol 191:175-81. 2008..Small-bowel radiography may be replaced by enteroscopy in the diagnosis of small-intestine lesions. We retrospectively elucidated the diagnostic yield of small-bowel radiography performed before double-balloon endoscopy...
Long-term remission of primary gastric T cell lymphoma associated with human T lymphotropic virus type 1: a report of two cases and review of the literatureKeiichi Tanaka
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Intern Med 46:1783-7. 2007..Although primary gastric T-cell lymphomas associated with HTLV-1 is characterized by an extremely poor prognosis, the present cases suggest that in the early stage, long-term survival can possibly be achieved with appropriate treatments...
Impact of serum total cholesterol on the incidence of gastric cancer in a population-based prospective study: the Hisayama studyKouichi Asano
Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Int J Cancer 122:909-14. 2008..In conclusion, our findings suggest that low serum cholesterol levels are an independent risk factor for developing gastric cancer, especially intestinal-type gastric cancer...
Gastric MALT lymphoma with t(14;18)(q32;q21) involving IGH and BCL2 genes that responded to Helicobacter pylori eradicationShotaro Nakamura
Department of Molecular Hisropathology, University of Cambridge, UK
J Clin Pathol 60:1171-3. 2007
Magnifying colonoscopy with narrow band imaging system for the diagnosis of dysplasia in ulcerative colitis: a pilot studyTakayuki Matsumoto
Departments of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Gastrointest Endosc 66:957-65. 2007..Narrow-band imaging (NBI) is a novel illumination technology for endoscopy that enhances vasculature of the GI tract...
Chronic nonspecific multiple ulcers of the small intestine: a proposal of the entity from Japanese gastroenterologists to Western enteroscopistsTakayuki Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Gastrointest Endosc 66:S99-107. 2007
Treatment of inflammatory immunologic disease 2. Anti-cytokine therapies in inflammatory bowel diseaseTakayuki Matsumoto
Department of Gastroenterology, Hyogo College of Medicine, Nishinomiya, Japan
Intern Med 46:1307-9. 2007
[A case of primary gastric malignant lymphoma perforated immediately after administration of chemotherapy]Sohei Yoshino
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
Nippon Shokakibyo Gakkai Zasshi 103:162-7. 2006..Complete remission was achieved by 2 cycles of postoperative chemotherapy together with rituximab...
Effect of the non-steroidal anti-inflammatory drug sulindac on colorectal adenomas of uncolectomized familial adenomatous polyposisTakayuki Matsumoto
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
J Gastroenterol Hepatol 21:251-7. 2006..The aim of the present study was to elucidate the effect of sulindac on uncolectomized familial adenomatous polyposis (FAP)...
A prospective study of dietary salt intake and gastric cancer incidence in a defined Japanese population: the Hisayama studyKentaro Shikata
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Int J Cancer 119:196-201. 2006..14-7.24]). Our findings suggest that high dietary salt intake is a significant risk factor for gastric cancer; moreover, this association was found to be strong in the presence of Helicobacter pylori infection with atrophic gastritis...
Accumulation of CCR5+ T cells around RANTES+ granulomas in Crohn's disease: a pivotal site of Th1-shifted immune response?Motoji Oki
Department of Internal Medicine Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan
Lab Invest 85:137-45. 2005..Together with the notion that granuloma cells are possible antigen-presenting cells, our results suggest that the noncaseating granulomas could be one of the crucial sites of Th1-shifted immune responses in Crohn's disease...
Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-alphaToshio Watanabe
Dept of Gastroenterology, Osaka City Univ Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
Am J Physiol Gastrointest Liver Physiol 287:G919-28. 2004..In conclusion, increased MCP-1 triggered by TNF-alpha may play a key role in gastric ulceration by regulating leukocyte recruitment and chemokine expression...
Does colitis associated with primary sclerosing cholangitis represent an actual subset of ulcerative colitis?Nobuhide Oshitani
Department of Gastroenterology, Osaka City University Post Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
Hepatogastroenterology 50:1830-5. 2003..The clinical course and endoscopic features of colitis associated with primary sclerosing cholangitis have not been well documented...
