Yasue Kimura

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint Significance of Accurate Human Epidermal Growth Factor Receptor-2 (HER2) Evaluation as a New Biomarker in Gastric Cancer
    Yasue Kimura
    Department of Gastroenterological Surgery, National Kyushu Medical Center, Clinical Research Institute, Fukuoka, Japan Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 34:4207-12. 2014
  2. ncbi request reprint Case of early adenosquamous carcinoma of the stomach
    Yasue Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 104:315-20. 2013
  3. ncbi request reprint Solitary splenic metastasis derived from esophageal cancer
    Yasue Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    Hepatogastroenterology 50:1336-7. 2003
  4. ncbi request reprint Vascular endothelial growth factor C expression correlates with lymphatic involvement and poor prognosis in patients with esophageal squamous cell carcinoma
    Yasue Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 0054, Japan
    Oncol Rep 10:1747-51. 2003
  5. ncbi request reprint Multimodal treatment strategy for clinical T3 thoracic esophageal cancer
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 20:4267-73. 2013
  6. ncbi request reprint Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka 812 8582, Japan
    Breast Cancer Res Treat 101:249-57. 2007
  7. ncbi request reprint Activation of PI3K/Akt signaling and hormone resistance in breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Breast Cancer 13:137-44. 2006
  8. ncbi request reprint The association between Akt activation and resistance to hormone therapy in metastatic breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Eur J Cancer 42:629-35. 2006
  9. doi request reprint Gastric cancer in the reconstructed gastric tube after radical esophagectomy: a single-center experience
    Eiji Oki
    Department of Gastroenterological Surgery, National Kyushu Cancer Center, 3 1 1 Notame, Minami Ku, Fukuoka, 811 1395, Japan
    Surg Today 41:966-9. 2011
  10. ncbi request reprint [Evaluation of multi-modality treatment for the patients with advanced esophageal cancer]
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
    Fukuoka Igaku Zasshi 93:259-65. 2002

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Significance of Accurate Human Epidermal Growth Factor Receptor-2 (HER2) Evaluation as a New Biomarker in Gastric Cancer
    Yasue Kimura
    Department of Gastroenterological Surgery, National Kyushu Medical Center, Clinical Research Institute, Fukuoka, Japan Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 34:4207-12. 2014
    ..The aim of the present study was to evaluate the frequency and accuracy of detection of HER2 expression by application of standard criteria in Japanese patients with gastric cancer...
  2. ncbi request reprint Case of early adenosquamous carcinoma of the stomach
    Yasue Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 104:315-20. 2013
    ..Therefore, future treatment for recurrent adenosquamous carcinoma of the stomach should be considered...
  3. ncbi request reprint Solitary splenic metastasis derived from esophageal cancer
    Yasue Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    Hepatogastroenterology 50:1336-7. 2003
    ..Transarterial embolization of the splenic artery was without effect. A splenectomy was then done and histological examination of the resected specimen revealed squamous cell carcinoma derived from the esophageal carcinoma...
  4. ncbi request reprint Vascular endothelial growth factor C expression correlates with lymphatic involvement and poor prognosis in patients with esophageal squamous cell carcinoma
    Yasue Kimura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 0054, Japan
    Oncol Rep 10:1747-51. 2003
    ..VEGF-C expression in ESCC may play a great key role in lymphatic spread and this may be a consideration in terms of deciding the most appropriate treatment...
  5. ncbi request reprint Multimodal treatment strategy for clinical T3 thoracic esophageal cancer
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 20:4267-73. 2013
    ..Our goal was to create a multimodal treatment strategy for patients with locally advanced esophageal cancer (EC)...
  6. ncbi request reprint Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka 812 8582, Japan
    Breast Cancer Res Treat 101:249-57. 2007
    ..Our results suggest that simultaneous PTEN LOH and HER2 overexpression enhances Akt activation and may thus lead to a negative PR expression...
  7. ncbi request reprint Activation of PI3K/Akt signaling and hormone resistance in breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Breast Cancer 13:137-44. 2006
    ..Our findings suggest that pAkt may be a useful predictor of resistance to endocrine therapy for breast cancer, while also suggesting that the inhibition of Akt may increase the efficacy of endocrine therapy...
  8. ncbi request reprint The association between Akt activation and resistance to hormone therapy in metastatic breast cancer
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Eur J Cancer 42:629-35. 2006
    ....
  9. doi request reprint Gastric cancer in the reconstructed gastric tube after radical esophagectomy: a single-center experience
    Eiji Oki
    Department of Gastroenterological Surgery, National Kyushu Cancer Center, 3 1 1 Notame, Minami Ku, Fukuoka, 811 1395, Japan
    Surg Today 41:966-9. 2011
    ..This study investigated 10 cases of gastric tube cancer in order to clarify the characteristics and the outcome of these patients...
  10. ncbi request reprint [Evaluation of multi-modality treatment for the patients with advanced esophageal cancer]
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
    Fukuoka Igaku Zasshi 93:259-65. 2002
    ..It is important to continue to clarify the factors influencing the effectiveness of preoperative HCR in the future. We hope that HCR will play an even more important role in treatment of esophageal cancer...
  11. ncbi request reprint Advances in esophageal surgery in elderly patients with thoracic esophageal cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Anticancer Res 33:1641-7. 2013
    ..To justify esophagectomy for elderly patients...
  12. ncbi request reprint Impact of second-line and later cetuximab-containing therapy and KRAS genotypes in patients with metastatic colorectal cancer: a multicenter study in Japan
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 44:1457-64. 2014
    ..This retrospective study evaluated the treatment outcomes and clinical relevance of the KRAS mutation status in Japanese metastatic colorectal cancer patients treated with second-line and later cetuximab-containing therapy...
  13. doi request reprint Gender differences in prognosis after esophagectomy for esophageal cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Surg Today 44:505-12. 2014
    ..The purpose of this study was to clarify the gender differences in the prognosis, as well as mortality and morbidity, of patients who have undergone esophagectomy for esophageal cancer...
  14. ncbi request reprint Pure laparoscopic right-sided hepatectomy in the semi-prone position for synchronous colorectal cancer with liver metastases
    Satoshi Ida
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    Asian J Endosc Surg 7:133-7. 2014
    ..The purpose of this study was to assess the feasibility of PULSAR for patients with primary colorectal cancer and SCRLM...
  15. ncbi request reprint Surgical resection for esophageal cancer synchronously or metachronously associated with head and neck cancer
    Masaru Morita
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 20:2434-9. 2013
    ..The purpose of this study was to clarify the clinical significance of esophagectomy for patients with esophageal cancer associated either synchronously or metachronously with head and neck cancer...
  16. ncbi request reprint Role of dihydropyrimidine dehydrogenase activity in patients with esophageal cancer
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Anticancer Res 22:3789-92. 2002
    ..We propose that determination of DPD activity prior to initiation of 5-FU-based chemotherapy for patients with esophageal cancer could aid in identifying those at risk for toxicity...
  17. ncbi request reprint S-1 in the treatment of advanced and recurrent gastric cancer: current state and future prospects
    Ikuo Takahashi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Gastric Cancer 6:28-33. 2003
    ..S-1 (TS-1) is a novel oral anticancer drug. Because of the excellent results of phase II studies, we continued to prescribe S-1 for advanced or recurrent gastric cancer after we participated in the phase I and II studies...
  18. ncbi request reprint Akt is frequently activated in HER2/neu-positive breast cancers and associated with poor prognosis among hormone-treated patients
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int J Cancer 118:284-9. 2006
    ..This finding suggests that inhibition of the Akt signaling pathway may increase the efficacy of hormone therapy and improve the prognosis of patients who receive adjuvant hormone therapy...
  19. doi request reprint Podoplanin is expressed at the invasive front of esophageal squamous cell carcinomas and is involved in collective cell invasion
    Yuichiro Nakashima
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Cancer Sci 104:1718-25. 2013
    ..05). These data suggest that podoplanin is significantly associated with and likely contributes to ESCC invasion in the absence of EMT...
  20. ncbi request reprint Mortalin is a prognostic factor of gastric cancer with normal p53 function
    Koji Ando
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Fukuoka, 821 8582, Japan
    Gastric Cancer 17:255-62. 2014
    ..Mortalin binds to p53 and prevents p53 from entering the nucleus. To understand the significance of mortalin in gastric cancer, we investigated the expression of mortalin and p53...
  21. ncbi request reprint Early report of correlation between the thermal dosage and the treatment effect of hyperthermia in combination with chemoradiotherapy for esophageal cancer patients
    Kaoru Kitamura
    Department of Surgery and Science Department of Surgery II, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hepatogastroenterology 49:1560-2. 2002
    ..It is known to be difficult to determine thermal dosage in clinical tumor treatment. The aim of this study is to examine whether the quantitative heating dose reflects the treatment effect in esophageal cancer...
  22. ncbi request reprint Overexpression of cyclooxygenase-2 and tumor angiogenesis in human gastric cancer
    Tadashi Koga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hepatogastroenterology 51:1626-30. 2004
    ....
  23. ncbi request reprint Simultaneous resection of colorectal cancer and liver metastases in the right lobe using pure laparoscopic surgery
    Koji Ando
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 821 8582, Japan
    Surg Today 44:1588-92. 2014
    ..The postoperative course was uneventful. In selected patients, laparoscopic hepatectomy for right lobe synchronous metastatic tumors can be safely performed simultaneously with colorectal surgery. ..
  24. ncbi request reprint Surgical resection of hypopharynx and cervical esophageal cancer with a history of esophagectomy for thoracic esophageal cancer
    Satoshi Ida
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg Oncol 21:1175-81. 2014
    ..The purpose of this study was to clarify the treatment outcomes of patients with metachronous PhCe cancer with a history of esophagectomy...
  25. ncbi request reprint Surgical and oncological advances in the treatment of esophageal cancer
    Takefumi Ohga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 131:S28-34. 2002
    ..These neoadjuvant therapies for esophageal cancer are done widely. The purpose of this study is to demonstrate the recent advances in surgical and oncological treatment...
  26. ncbi request reprint Interrelation between expression of matrix metalloproteinase 7 and beta-catenin in esophageal cancer
    Hirohi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Dig Dis Sci 47:2738-42. 2002
    ..MMP-7 expression correlates with penetrating tumor progression in esophageal cancer. Nuclear translocation of beta-catenin, without mutations in beta-catenin exon 3, is associated with MMP-7 expression...
  27. ncbi request reprint [Treatment of gastric cancer: current state and future prospect]
    Yoshihiko Maehara
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Fukuoka Igaku Zasshi 94:285-95. 2003
  28. ncbi request reprint No hypersensitive estrogen receptor-alpha mutation (K303R) in Japanese breast carcinomas
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    Breast Cancer Res Treat 84:289-92. 2004
    ..No K303R mutation was found in the ERalpha gene in these breast lesions obtained from Japanese patients...
  29. ncbi request reprint Biologic and clinical significance of squamous epithelial dysplasia of the esophagus
    Hiroshi Saeki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Japan
    Surgery 131:S22-7. 2002
    ..It is essential to detect and treat these early lesions endoscopically. Hopefully the findings of further studies of dysplasia can help to elucidate the mechanism of carcinogenesis in esophageal squamous cell carcinoma...
  30. ncbi request reprint Granulomatous lobular mastitis misdiagnosed as breast carcinoma
    Eriko Tokunaga
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Breast J 10:261-2. 2004
  31. ncbi request reprint Estimation of angiogenesis with anti-CD105 immunostaining in the process of colorectal cancer development
    Kazunari Akagi
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 131:S109-13. 2002
    ..We hypothesized that microvessel quantification by means of CD105 might be useful for measuring angiogenesis in the colorectal adenoma-carcinoma sequence...
  32. ncbi request reprint Correlation with bone metastasis and high expression of CK 19 mRNA measured by quantitative RT-PCR in the bone marrow of breast cancer patients
    Eriko Tokunaga
    Breast J 9:440-2. 2003