Shigenobu Kanba

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint [Understanding psychiatric diseases caused by stress: neurogenesis in hippocampus and mental functions]
    Shigenobu Kanba
    Nihon Yakurigaku Zasshi 128:3-7. 2006
  2. pmc Gamma band neural synchronization deficits for auditory steady state responses in bipolar disorder patients
    Yuko Oda
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    PLoS ONE 7:e39955. 2012
  3. doi request reprint Guideline for treatment of bipolar disorder by the Japanese Society of Mood Disorders, 2012
    Shigenobu Kanba
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Clin Neurosci 67:285-300. 2013
  4. pmc Efficacy and safety of olanzapine for treatment of patients with bipolar depression: Japanese subpopulation analysis of a randomized, double-blind, placebo-controlled study
    Hideaki Katagiri
    Lilly Research Laboratories, Sannomiya Plaza Bldg, 7 1 5, Isogamidori, Chuo Ku, Kobe 651 0086, Japan
    BMC Psychiatry 13:138. 2013
  5. pmc Exome sequencing identifies a novel missense variant in RRM2B associated with autosomal recessive progressive external ophthalmoplegia
    Atsushi Takata
    Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    Genome Biol 12:R92. 2011
  6. doi request reprint Inhibitory effects of SSRIs on IFN-γ induced microglial activation through the regulation of intracellular calcium
    Hideki Horikawa
    Department of Neuropsychiatry, Graduate School of Medicine, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka City, Fukuoka 812 8582, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 34:1306-16. 2010
  7. doi request reprint Reduced high and low frequency gamma synchronization in patients with chronic schizophrenia
    Rikako Tsuchimoto
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Schizophr Res 133:99-105. 2011
  8. doi request reprint Inhibitory effects of aripiprazole on interferon-gamma-induced microglial activation via intracellular Ca2+ regulation in vitro
    Takahiro Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Neurochem 106:815-25. 2008
  9. doi request reprint Aripiprazole inhibits superoxide generation from phorbol-myristate-acetate (PMA)-stimulated microglia in vitro: implication for antioxidative psychotropic actions via microglia
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka 812 8582, Japan
    Schizophr Res 129:172-82. 2011
  10. doi request reprint Working memory dysfunction in obsessive-compulsive disorder: a neuropsychological and functional MRI study
    Tomohiro Nakao
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    J Psychiatr Res 43:784-91. 2009

Collaborators

Detail Information

Publications75

  1. ncbi request reprint [Understanding psychiatric diseases caused by stress: neurogenesis in hippocampus and mental functions]
    Shigenobu Kanba
    Nihon Yakurigaku Zasshi 128:3-7. 2006
  2. pmc Gamma band neural synchronization deficits for auditory steady state responses in bipolar disorder patients
    Yuko Oda
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    PLoS ONE 7:e39955. 2012
    ..BD patients are characterized by deficits in gamma band oscillations, which may be associated with GABA inhibitory interneuronal activity dysfunction...
  3. doi request reprint Guideline for treatment of bipolar disorder by the Japanese Society of Mood Disorders, 2012
    Shigenobu Kanba
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Clin Neurosci 67:285-300. 2013
    ..The first draft, prepared in this manner, was further revised through a process of critical investigation by all committee members to produce the final edition. ..
  4. pmc Efficacy and safety of olanzapine for treatment of patients with bipolar depression: Japanese subpopulation analysis of a randomized, double-blind, placebo-controlled study
    Hideaki Katagiri
    Lilly Research Laboratories, Sannomiya Plaza Bldg, 7 1 5, Isogamidori, Chuo Ku, Kobe 651 0086, Japan
    BMC Psychiatry 13:138. 2013
    ..The efficacy and safety of olanzapine monotherapy are evaluated in Japanese patients from a large, global study of bipolar depression...
  5. pmc Exome sequencing identifies a novel missense variant in RRM2B associated with autosomal recessive progressive external ophthalmoplegia
    Atsushi Takata
    Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    Genome Biol 12:R92. 2011
    ..We previously reported a case of PEO with unidentified genetic etiology. The patient was born of a first-cousin marriage. Therefore, the recessive form of inheritance was suspected...
  6. doi request reprint Inhibitory effects of SSRIs on IFN-γ induced microglial activation through the regulation of intracellular calcium
    Hideki Horikawa
    Department of Neuropsychiatry, Graduate School of Medicine, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka City, Fukuoka 812 8582, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 34:1306-16. 2010
    ..Our results suggest that the inhibitory effect of paroxetine and sertraline on microglial activation may not be a prerequisite for antidepressant function, but an additional beneficial effect...
  7. doi request reprint Reduced high and low frequency gamma synchronization in patients with chronic schizophrenia
    Rikako Tsuchimoto
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Schizophr Res 133:99-105. 2011
    ..The current study highlights the high and low frequency gamma abnormalities and provides clear evidence that schizophrenia is characterized by abnormalities in neural circuitry...
  8. doi request reprint Inhibitory effects of aripiprazole on interferon-gamma-induced microglial activation via intracellular Ca2+ regulation in vitro
    Takahiro Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Neurochem 106:815-25. 2008
    ..Antipsychotics may therefore have a potentially useful therapeutic effect on patients with schizophrenia by reducing the microglial inflammatory reactions...
  9. doi request reprint Aripiprazole inhibits superoxide generation from phorbol-myristate-acetate (PMA)-stimulated microglia in vitro: implication for antioxidative psychotropic actions via microglia
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka 812 8582, Japan
    Schizophr Res 129:172-82. 2011
    ..Our results imply that aripiprazole may have psychotropic effects by reducing the microglial oxidative reactions and following neuronal reactions, which puts forward a novel therapeutic hypothesis in schizophrenia research...
  10. doi request reprint Working memory dysfunction in obsessive-compulsive disorder: a neuropsychological and functional MRI study
    Tomohiro Nakao
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    J Psychiatr Res 43:784-91. 2009
    ..Furthermore, our results suggested that symptom severity and symptom subtype such as obsessions/checking might affect neuropsychological dysfunction and related brain activities...
  11. doi request reprint Duration effect of obsessive-compulsive disorder on cognitive function: a functional MRI study
    Tomohiro Nakao
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Depress Anxiety 26:814-23. 2009
    ..The inconsistency of previous reports examining cognitive function in obsessive-compulsive disorder (OCD) suggests its heterogeneity. In this study, we examined the effect of illness duration on cognitive function in OCD...
  12. ncbi request reprint Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid beta and interferon-gamma-induced microglial activation
    Sadayuki Hashioka
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Free Radic Biol Med 42:945-54. 2007
    ..These results suggest that PS/PC liposomes have both neuroprotective and antioxidative properties through the inhibition of microglial activation, thus supporting the nootropic and antidementia effect of PS...
  13. doi request reprint Auditory gating deficit to human voices in schizophrenia: a MEG study
    Yoji Hirano
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Schizophr Res 117:61-7. 2010
    ..We examined the functioning of auditory gating and its relationship with the clinical symptoms in schizophrenia...
  14. doi request reprint Differentiation between bipolar disorder and schizophrenia revealed by neural oscillation to speech sounds: an MEG study
    Naoya Oribe
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Bipolar Disord 12:804-12. 2010
    ..The current study tested the hypothesis that the eNO to speech sounds could be differentiated between BP and SZ patients...
  15. ncbi request reprint Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide
    Sadayuki Hashioka
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka, 812 8582 Japan
    Exp Neurol 206:33-42. 2007
    ..On the other hand, the mood stabilizer and anti-manic agent lithium chloride has mixed effects on IFN-gamma-induced microglial activation...
  16. doi request reprint Brain-derived neurotrophic factor induces sustained elevation of intracellular Ca2+ in rodent microglia
    Yoshito Mizoguchi
    Department of Neuropsychiatry, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    J Immunol 183:7778-86. 2009
    ....
  17. doi request reprint Decreased spatial frequency sensitivities for processing faces in male patients with chronic schizophrenia
    Choji Obayashi
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Clin Neurophysiol 120:1525-33. 2009
    ..We investigated whether electrophysiological abnormalities exist in visual processing for spatial frequency (SF)-filtered neutral/emotional faces in schizophrenics...
  18. doi request reprint Altered face inversion effect and association between face N170 reduction and social dysfunction in patients with schizophrenia
    Tomoya Tsunoda
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Neurophysiol 123:1762-8. 2012
    ..This face inversion effect (FIE) presumably reflects a disruption of face-specific configuration processing. The present study investigated FIE and the associations between social functioning and N170 in patients with schizophrenia...
  19. doi request reprint Abnormal neural oscillatory activity to speech sounds in schizophrenia: a magnetoencephalography study
    Shogo Hirano
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Neurosci 28:4897-903. 2008
    ..Moreover, the present study suggests that schizophrenia might be characterized by an opposite pattern of hemispheric lateralization in auditory evoked oscillations...
  20. doi request reprint Predictors of treatment response to fluvoxamine in obsessive-compulsive disorder: an fMRI study
    Hirokuni Sanematsu
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Psychiatr Res 44:193-200. 2010
    ..Our results suggest that pre-treatment activation in the right cerebellum and in the left STG predict subsequent reduction in OCD symptom severity. There is every possibility that fMRI can be used as a tool to predict treatment response...
  21. ncbi request reprint Age-related disturbance of memory and CREB phosphorylation in CA1 area of hippocampus of rats
    Koutaro Kudo
    Department of Neuropsychiatry, Interdisciplinary Graduate School of Medicine and Engineering, Yamanashi University, Yamanashi, Japan
    Brain Res 1054:30-7. 2005
    ..The close relationship between behavioral performance and CREB phosphorylation in the CA1 region suggests that hippocampal CREB is involved in age-related decline of learning and memory...
  22. ncbi request reprint The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-gamma
    Qian Bian
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi Higashi ku, Fukuoka, 812 8582, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:42-8. 2008
    ....
  23. ncbi request reprint A decreased survival of proliferated cells in the hippocampus is associated with a decline in spatial memory in aged rats
    Henny Wati
    Department of Neuropsychiatry, Interdisciplinary Graduate School of Medicine and Engineering, Yamanashi University, Yamanashi, Japan
    Neurosci Lett 399:171-4. 2006
    ..These results suggest that the integration of newly generated neurons into hippocampal circuitry is decreased with aging, this phenomenon may, in part, explain the decline in learning and memory in aged rats...
  24. doi request reprint Preattentive visual change detection as reflected by the mismatch negativity (MMN)--evidence for a memory-based process
    Toshihiko Maekawa
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Neurosci Res 65:107-12. 2009
    ..These results suggest that memory-based change detection underlies vMMN. Therefore, vMMN is useful to study visual sensory memory function...
  25. doi request reprint Does the 'hikikomori' syndrome of social withdrawal exist outside Japan? A preliminary international investigation
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi Higashi ku, Fukuoka, 812 8582, Japan
    Soc Psychiatry Psychiatr Epidemiol 47:1061-75. 2012
    ..To explore whether the 'hikikomori' syndrome (social withdrawal) described in Japan exists in other countries, and if so, how patients with the syndrome are diagnosed and treated...
  26. doi request reprint fMRI of patients with social anxiety disorder during a social situation task
    Tomohiro Nakao
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Neurosci Res 69:67-72. 2011
    ..The findings contribute to previous findings that revealed abnormal activities of emotion-related regions including the amygdala and insular cortex during facial perception in SAD...
  27. ncbi request reprint Risperidone significantly inhibits interferon-gamma-induced microglial activation in vitro
    Takahiro Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi Higashi ku, Fukuoka 812 8582, Japan
    Schizophr Res 92:108-15. 2007
    ....
  28. doi request reprint Introducing the concept of modern depression in Japan; an international case vignette survey
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Affect Disord 135:66-76. 2011
    ..We explored whether MTD is frequently seen in Japan and also in other countries, and if so, how patients with MTD are diagnosed and treated...
  29. doi request reprint Selective impairment of optic flow perception in amnestic mild cognitive impairment: evidence from event-related potentials
    Takao Yamasaki
    Department of Clinical Neurophysiology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Alzheimers Dis 28:695-708. 2012
    ..Therefore, OF-specific P200 can be useful for detecting early functional changes of the brain in aMCI...
  30. doi request reprint Regional gray and white matter volume abnormalities in obsessive-compulsive disorder: a voxel-based morphometry study
    Osamu Togao
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Psychiatry Res 184:29-37. 2010
    ..The results suggested that WM volume abnormalities in the orbitofrontal region, anterior limb of the internal capsule, and anterior cingulate gyrus would imply abnormalities in the pathways of frontal-striatal circuits...
  31. ncbi request reprint Review of neurophysiological findings in patients with schizophrenia
    Toshiaki Onitsuka
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Clin Neurosci 67:461-70. 2013
    ..Exploring the associations between neural substrates, including neurotransmitter systems, and neurophysiological findings, will lead to a more comprehensive understanding of the pathophysiology of schizophrenia...
  32. doi request reprint Nominal association between a polymorphism in DGKH and bipolar disorder detected in a meta-analysis of East Asian case-control samples
    Atsushi Takata
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Clin Neurosci 65:280-5. 2011
    ..However, the results of these GWAS were not necessarily consistent, indicating the importance of replication studies. In this study, we tested the genetic association of DGKH, DFNB31 and SORCS2 with BD...
  33. doi request reprint Midlife and late-life blood pressure and dementia in Japanese elderly: the Hisayama study
    Toshiharu Ninomiya
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashiku, Fukuoka City 812 8582, Japan
    Hypertension 58:22-8. 2011
    ..Midlife hypertension is especially strongly associated with a greater risk of vascular dementia, regardless of late-life blood pressure levels...
  34. doi request reprint Differential neural network of checking versus washing symptoms in obsessive-compulsive disorder
    Keitaro Murayama
    Department of Neuropsychiatry, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 40:160-6. 2013
    ..We suggest that the caudate and ACC are associated with checking rituals and that large cortical brain regions are related to washing rituals...
  35. doi request reprint Clinicopathological outline of dementia with Lewy bodies applying the revised criteria: the Hisayama study
    Kouhei Fujimi
    Department of Neuropathology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Brain Pathol 18:317-25. 2008
    ....
  36. ncbi request reprint Effect of yokukansan on the behavioral and psychological symptoms of dementia in elderly patients with Alzheimer's disease
    Akira Monji
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kysushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 33:308-11. 2009
    ..The aim of this study was to investigate the effects of yokukansan (YKS) on the behavioral and psychological symptoms of dementia (BPSD) in elderly patients with Alzheimer's disease (AD)...
  37. ncbi request reprint Impact of biopsychosocial factors on psychiatric training in Japan and overseas: are psychiatrists oriented to mind, brain, or sociocultural issues?
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Clin Neurosci 64:520-30. 2010
    ..To clarify the impact of biopsychosocial factors on psychiatric training under the new and traditional postgraduate medical education system in Japan and to compare them with young psychiatrists from other countries...
  38. ncbi request reprint Different SPECT findings before and after Capgras' syndrome in interictal psychosis
    Hideki Horikawa
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Epilepsy Behav 9:189-92. 2006
    ..The enhanced hypoperfusion demonstrated by SPECT in the present case seems to indicate a right interhemispheric disconnection resulting in the occurrence of Capgras' syndrome...
  39. ncbi request reprint Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia
    Sadayuki Hashioka
    Department of Neuropsychiatry, Graduate School of Medicine, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Neurochem Int 50:499-506. 2007
    ..Therefore, PS/PC liposomes appear to have both neuroprotective and anti-oxidative properties through the inhibition of microglial activation...
  40. pmc Minocycline modulates human social decision-making: possible impact of microglia on personality-oriented social behaviors
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    PLoS ONE 7:e40461. 2012
    ..Therefore, using minocycline, a tetracycline antibiotic and the most famous microglial inhibitor, is one of the best alternative approaches to clarify microglial functions on human social/mental activities...
  41. ncbi request reprint Auditory sensory gating to the human voice: a preliminary MEG study
    Yoji Hirano
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Res 163:260-9. 2008
    ..These results therefore demonstrate the presence of sensory gating for auditory inputs of the human voice in the primary auditory cortex and the auditory association area...
  42. doi request reprint Undergraduate medical students' attitudes towards psychiatry: an international cross-sectional survey between India and Japan
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Int Rev Psychiatry 25:378-84. 2013
    ..The findings of the current study provide insight in to the attitudes of third-year medical students from India and Japan towards psychiatric patients...
  43. pmc Elevated depressive symptoms in metabolic syndrome in a general population of Japanese men: a cross-sectional study
    Atsuko Sekita
    Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    BMC Public Health 13:862. 2013
    ..Uncertainty still surrounds the association between metabolic syndrome (MetS) and depression. We aimed to evaluate the association between MetS and elevated depressive symptoms in a general Japanese population...
  44. doi request reprint Pretreatment of aripiprazole and minocycline, but not haloperidol, suppresses oligodendrocyte damage from interferon-γ-stimulated microglia in co-culture model
    Yoshihiro Seki
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Schizophr Res 151:20-8. 2013
    ..These results put forward a novel therapeutic hypothesis in schizophrenia research. Future in vivo studies to confirm the present results should be performed...
  45. pmc Mechanism for retardation of amyloid fibril formation by sugars in Vλ6 protein
    Masahiro Abe
    Department of Protein Structure, Function and Design, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Protein Sci 22:467-74. 2013
    ..However, the type of sugar had no effect on the elongation of amyloid fibrils. Therefore, it was concluded that sugar affected the thermodynamic stability of 3Hmut Wil but not the elongation of amyloid fibrils...
  46. doi request reprint Apolipoprotein genotype for prediction of Alzheimer's disease in older Japanese: the Hisayama Study
    Tomoyuki Ohara
    Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Geriatr Soc 59:1074-9. 2011
    ..To estimate the effects of the apolipoprotein E (APOE)-ɛ4 allele on the development of dementia and to elucidate its usefulness in the risk prediction of dementia in Japanese...
  47. ncbi request reprint Differences in the preferred antipsychotics for acute schizophrenia among young psychiatrists in two regions of Japan
    Masaru Tateno
    Department of Neuropsychiatry, School of Medicine, Sapporo Medical University, South 1, West 16, Chuo Ku, Sapporo, Hokkaido 0608543, Japan
    Asian J Psychiatr 3:60-3. 2010
    ..Effective emergency intervention for acute schizophrenia is of great concern to psychiatrists. To investigate whether differences in attitudes toward pharmacotherapy exist in the emergency setting, we surveyed two regions of Japan...
  48. ncbi request reprint Cytokines and schizophrenia: Microglia hypothesis of schizophrenia
    Akira Monji
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Clin Neurosci 63:257-65. 2009
    ..The microglia hypothesis of schizophrenia may shed new light on the therapeutic strategy for schizophrenia...
  49. ncbi request reprint Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: the Hisayama Study
    Kouhei Fujimi
    Department of Neuropathology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Dement Geriatr Cogn Disord 23:423-31. 2007
    ..In addition, it has been suggested that alterations in the balance of polyunsaturated fatty acids are associated with brain dysfunctions such as neurodegerative pathologies of the aging brain...
  50. doi request reprint Development of 2-hour suicide intervention program among medical residents: first pilot trial
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Clin Neurosci 64:531-40. 2010
    ..In this article, we introduce our newly developed suicide intervention program among medical residents...
  51. ncbi request reprint Impairment of theory of mind in patients in remission following first episode of schizophrenia
    Yumiko Inoue
    Department of Neuropsychiatry, Graduate School of Medicine and Engineering University of Yamanashi, 1110 Shimokato, Tamaho cho, Yamanashi 409 3898, Japan
    Eur Arch Psychiatry Clin Neurosci 256:326-8. 2006
    ..Patients with schizophrenia in remission showed statistically significant impairment in the ToM tasks. ToM impairment was not correlated with psychiatric symptoms. Thus, ToM deficit in schizophrenia may be a trait marker...
  52. ncbi request reprint [Introduction of treatment guideline for bipolar disorders made by the Japanese Society of Mood Disorders]
    Shigenobu Kanba
    Department of Neuropsychiatry, Graduate School of Medical Sciences, University of Kyushu
    Seishin Shinkeigaku Zasshi 113:863-6. 2011
    ..In an annual symposium, the authors will talk about the details of treatments for depression, mania and maintenance. In addition, some instructions and cautions will be stated regarding appropriate use of guideline...
  53. ncbi request reprint Neurophysiological findings in patients with bipolar disorder
    Toshiaki Onitsuka
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Suppl Clin Neurophysiol 62:197-206. 2013
    ..Moreover, neurophysiological approaches may reveal appropriate biological indices to distinguish bipolar disorder and schizophrenia, aiding the development of more effective medication at the early stages of illness...
  54. doi request reprint A simple and high-yield method for preparation of rat microglial cultures utilizing Aclar plastic film
    Yoshihiro Seki
    Department of Neuropathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Neuropathology 31:215-22. 2011
    ..SMK also showed phagocytic activity. In conclusion, this method resulted in a high-yield preparation of microglial cultures with ease and reproducibility...
  55. doi request reprint Association analysis of adenosine A1 receptor gene (ADORA1) polymorphisms with schizophrenia in a Japanese population
    Leo Gotoh
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi ku, Japan
    Psychiatr Genet 19:328-35. 2009
    ..Therefore, we investigated the contribution of genetic variations of ADORA1 to the pathophysiological mechanisms of Japanese schizophrenia patients...
  56. ncbi request reprint Ginseng enhances contextual fear conditioning and neurogenesis in rats
    ChunXiang Qiao
    Department of Neuropsychiatry, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Japan
    Neurosci Res 51:31-8. 2005
    ..Thus, an increase in CFC-related neurogenesis may be one mechanism of Ginseng's properties to enhance learning ability...
  57. ncbi request reprint Functional MRI study of brain activation alterations in patients with obsessive-compulsive disorder after symptom improvement
    Maiko Nabeyama
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Psychiatry Res 163:236-47. 2008
    ..Our findings suggest that dysfunction of the posterior brain regions, especially the cerebellum, is involved in the pathogenesis of OCD, and that normalization in function can occur with improvement of OC symptoms...
  58. ncbi request reprint Evidence for the binding of phosphate ion to the C-terminus region in Abeta1-40 using heteronuclear NMR analyses
    Makiko Nagata-Uchiyama
    Laboratory of Protein Structure, Function and Design, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
    Protein Pept Lett 17:176-80. 2010
    ..Therefore, we suggested that phosphate ions interacted with the potential beta-strand region in Abeta1-40 to be hard to form beta-sheet in Abeta 1-40, resulting in retardation of the amyloid fibril formation...
  59. ncbi request reprint A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole for the treatment of acute manic or mixed episodes in Asian patients with bipolar I disorder (the AMAZE study)
    Shigenobu Kanba
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    World J Biol Psychiatry 15:113-21. 2014
    ..Conclusions. Aripiprazole had significantly greater efficacy than placebo for the treatment of acute manic or mixed episodes associated with bipolar I disorder in Asian patients. Treatment was generally safe and well tolerated. ..
  60. doi request reprint Peritraumatic Distress Inventory as a predictor of post-traumatic stress disorder after a severe motor vehicle accident
    Daisuke Nishi
    Department of Psychiatry, National Disaster Medical Center, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Psychiatry Clin Neurosci 64:149-56. 2010
    ..The aim of this study was to examine the utility of the Peritraumatic Distress Inventory (PDI) as a predictor of subsequent post-traumatic stress disorder (PTSD) in severe motor vehicle accident survivors...
  61. ncbi request reprint Depletion of intracellular Ca2+ store itself may be a major factor in thapsigargin-induced ER stress and apoptosis in PC12 cells
    Ichiro Yoshida
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Neurochem Int 48:696-702. 2006
    ....
  62. ncbi request reprint [Brain science in emotional memory: role of the hippocampus]
    Shigenobu Kanba
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University
    Fukuoka Igaku Zasshi 95:281-5. 2004
  63. ncbi request reprint Aconiti tuber increases plasma nitrite and nitrate levels in humans
    Kazuo Yamada
    Department of Neuropsychiatry, University of Yamanashi, Interdisciplinary Graduate School of Medicine and Engineering, 1110 Shimogato, Tamaho cho, Yamanashi 409 3898, Japan
    J Ethnopharmacol 96:165-9. 2005
    ..There was a statistically significant increase in the p-NOx level of the A-group as compared to the C-group (d.f.=1,22, F=9.38, p=0.006). The results suggest that Aconiti tuber may increase NO production in humans...
  64. ncbi request reprint Attitudes of early-career psychiatrists in Japan toward child and adolescent psychiatry and their career decision
    Masaru Tateno
    Department of Neuropsychiatry, Sapporo Medical University, Sapporo, Japan
    Psychiatry Clin Neurosci 64:199-201. 2010
    ..1%) in their fourth-10th year answered that they had interest in CAP. Psychiatry rotations with adequate CAP cases may be necessary to attract early-career psychiatrists to CAP...
  65. pmc Are microglia minding us? Digging up the unconscious mind-brain relationship from a neuropsychoanalytic approach
    Takahiro A Kato
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University Fukuoka, Japan Innovation Center for Medical Redox Navigation, Kyushu University Fukuoka, Japan
    Front Hum Neurosci 7:13. 2013
    ..Microglia have the potential to bridge the huge gap between neuroscience, biological psychiatry, psychology and psychoanalysis as a key player to connect the conscious and the unconscious world...
  66. ncbi request reprint Amyloid-beta fibril formation is not necessarily required for microglial activation by the peptides
    Sadayuki Hashioka
    Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Neurochem Int 47:369-76. 2005
    ..These results suggest that Abeta fibril formation is not necessarily required for microglial activation by the peptides...
  67. ncbi request reprint Functional characterization of mismatch negativity to a visual stimulus
    Toshihiko Maekawa
    Department of Clinical Neurophysiology Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashiku, Fukuoka 812 8582, Japan
    Clin Neurophysiol 116:2392-402. 2005
    ..To record mismatch negativity (MMN) to a visual stimulus fulfilling similar criteria to those of auditory MMN (A-MMN)...
  68. ncbi request reprint Temporal changes in the expression of brain-derived neurotrophic factor mRNA in the ventromedial nucleus of the hypothalamus of the developing rat brain
    Nobuhiro Sugiyama
    Department of Neuropsychiatry, University of Yamanashi Faculty of Medicine, Tamaho, Yamanashi 409 3898, Japan
    Brain Res Mol Brain Res 115:69-77. 2003
    ..These results suggest that localized and high level expression of BDNF mRNA in the neonatal VMN plays an important role in its neural organization and functional development...
  69. ncbi request reprint Interictal psychosis after stroke with forced normalization
    Tomoyuki Ohara
    J Neuropsychiatry Clin Neurosci 18:557-9. 2006
  70. ncbi request reprint Personality assessment based on the five-factor model of personality structure in patients with primary open-angle glaucoma
    Fumihiko Mabuchi
    Department of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409 3898, Japan
    Jpn J Ophthalmol 49:31-5. 2005
    ..However, none of the previous studies used a common structural theory of personality. In this study, we conducted a multicenter cross-sectional case-control study using the recently established five-factor model of personality structure...
  71. ncbi request reprint Deficiency of theory of mind in patients with remitted mood disorder
    Yumiko Inoue
    Department of Neuropsychiatry, Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan
    J Affect Disord 82:403-9. 2004
    ..In this study, we aimed to test ToM ability among patients with unipolar or bipolar depression currently in remission...
  72. ncbi request reprint Cerebral white matter degeneration in frontotemporal dementia detected by diffusion-weighted magnetic resonance imaging
    Takashi Yoshiura
    Department of Clinical Radiology, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Acad Radiol 13:1373-8. 2006
    ..We studied FTD patients using DWI to determine whether microstructural changes in white matter can be detected in vivo...
  73. ncbi request reprint A selective increase in phosphorylation of cyclic AMP response element-binding protein in hippocampal CA1 region of male, but not female, rats following contextual fear and passive avoidance conditioning
    Koutarou Kudo
    Department of Neuropsychiatry, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Tamaho, Yamanashi 409 3898, Japan
    Brain Res 1024:233-43. 2004
    ..The close relationship between behavioral performance and CREB phosphorylation in the CA1 region suggests that hippocampal CREB is involved in the sex difference in some forms of learning and memory...
  74. ncbi request reprint Mapping of subcortical white matter abnormality in Alzheimer's disease using diffusion-weighted magnetic resonance imaging
    Takashi Yoshiura
    Department of Clinical Radiology, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Acad Radiol 13:1460-4. 2006
    ..We studied the spatial distribution of the subcortical WM abnormality using diffusion-weighted magnetic resonance imaging (DWI)...
  75. ncbi request reprint Effectiveness of aroma on work efficiency: lavender aroma during recesses prevents deterioration of work performance
    Reiko Sakamoto
    Yamanashi Prefectural University, 5 11 1 Iida, Kofu, Yamanashi 400 0035, Japan
    Chem Senses 30:683-91. 2005
    ..No such effect was noted for the jasmine group. Although lavender is a sedative-type aroma, use during recess periods after accumulation of fatigue seems to prevent deterioration of performance in subsequent work sessions...