Tetsuhide Ito

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint Pancreatic pseudocyst after acute organophosphate poisoning
    Ken Kawabe
    Department of Medicine and Bioregulatory Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 97:123-9. 2006
  2. pmc Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, 3 1 1 Maidashi Higashi ku, Fukuoka, Japan
    Invest New Drugs 31:1265-74. 2013
  3. pmc Everolimus for advanced pancreatic neuroendocrine tumours: a subgroup analysis evaluating Japanese patients in the RADIANT-3 trial
    Tetsuhide Ito
    Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Jpn J Clin Oncol 42:903-11. 2012
  4. pmc Association of long-term proton pump inhibitor therapy with bone fractures and effects on absorption of calcium, vitamin B12, iron, and magnesium
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Curr Gastroenterol Rep 12:448-57. 2010
  5. ncbi request reprint Evaluation of pancreatic endocrine and exocrine function in patients with autoimmune pancreatitis
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Pancreas 34:254-9. 2007
  6. doi request reprint Epidemiological study of pancreatic diabetes in Japan in 2005: a nationwide study
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pancreas 39:829-35. 2010
  7. doi request reprint Characteristics of pancreatic diabetes in patients with autoimmune pancreatitis
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    J Dig Dis 12:210-6. 2011
  8. pmc Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis
    Yoshifumi Ino
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, and Department of Gastroenterology, Saiseikai Fukuoka General Hospital, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastroenterol 14:6382-7. 2008
  9. ncbi request reprint VIP attenuation of the severity of experimental pancreatitis is due to VPAC1 receptor-mediated inhibition of cytokine production
    Mizuho Kojima
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pancreas 30:62-70. 2005
  10. doi request reprint Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol 45:234-43. 2010

Detail Information

Publications81

  1. ncbi request reprint Pancreatic pseudocyst after acute organophosphate poisoning
    Ken Kawabe
    Department of Medicine and Bioregulatory Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 97:123-9. 2006
    ..Acute pancreatitis and hyperamylasemia are known to be possible complications of acute OP. It is necessary to examine and assess pancreatic damage in patients with acute OP...
  2. pmc Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, 3 1 1 Maidashi Higashi ku, Fukuoka, Japan
    Invest New Drugs 31:1265-74. 2013
    ..Pancreatic neuroendocrine tumors (NETs) are rare but are frequently diagnosed at advanced stages and require systemic therapy...
  3. pmc Everolimus for advanced pancreatic neuroendocrine tumours: a subgroup analysis evaluating Japanese patients in the RADIANT-3 trial
    Tetsuhide Ito
    Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Jpn J Clin Oncol 42:903-11. 2012
    ..The purpose of this analysis was to investigate the efficacy and safety of everolimus in the Japanese subgroup enrolled in the RADIANT-3 study...
  4. pmc Association of long-term proton pump inhibitor therapy with bone fractures and effects on absorption of calcium, vitamin B12, iron, and magnesium
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Curr Gastroenterol Rep 12:448-57. 2010
    ....
  5. ncbi request reprint Evaluation of pancreatic endocrine and exocrine function in patients with autoimmune pancreatitis
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Pancreas 34:254-9. 2007
    ..The aim of this study is to evaluate pancreatic functions in AIP compared with those of chronic pancreatitis (CP)...
  6. doi request reprint Epidemiological study of pancreatic diabetes in Japan in 2005: a nationwide study
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pancreas 39:829-35. 2010
    ..There have been few epidemiological studies on pancreatic diabetes. In this study, we determined the incidence and pathology of pancreatic diabetes in Japan...
  7. doi request reprint Characteristics of pancreatic diabetes in patients with autoimmune pancreatitis
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    J Dig Dis 12:210-6. 2011
    ..Although patients with autoimmune pancreatitis (AIP) tend to have concurrent diverse disorders, very few studies have focused on diabetes mellitus (DM) coexisting with AIP...
  8. pmc Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis
    Yoshifumi Ino
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, and Department of Gastroenterology, Saiseikai Fukuoka General Hospital, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastroenterol 14:6382-7. 2008
    ..To evaluate the efficacy of continuous regional arterial infusion therapy (CRAI) with gabexate mesilate and antibiotics for severe acute pancreatitis (SAP)...
  9. ncbi request reprint VIP attenuation of the severity of experimental pancreatitis is due to VPAC1 receptor-mediated inhibition of cytokine production
    Mizuho Kojima
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pancreas 30:62-70. 2005
    ..Therefore, we investigated the effects of VIP and selective agonists for 2 subtypes of VIP receptor (VPAC1-R and VPAC2-R agonist) on acute pancreatitis...
  10. doi request reprint Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol 45:234-43. 2010
    ..There have been few epidemiological studies on gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in Japan...
  11. doi request reprint Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats
    Toshiaki Ishibashi
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Gastroenterol 43:79-85. 2008
    ..To investigate the role of MCP-1 in acute pancreatitis and to seek possible therapeutic means, we evaluated the effect of a plasmid expression vector containing a dominant-negative mutant MCP-1 gene (mMCP-1)...
  12. doi request reprint High EGFR mRNA expression is a prognostic factor for reduced survival in pancreatic cancer after gemcitabine-based adjuvant chemotherapy
    Hayato Fujita
    Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan
    Int J Oncol 38:629-41. 2011
    ....
  13. pmc Retroperitoneal fibrosis associated with immunoglobulin G4-related disease
    Nao Fujimori
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    World J Gastroenterol 19:35-41. 2013
    ..However, the epidemiology, treatment for recurring retroperitoneal fibrosis, and long-term prognosis are still largely unknown. Further analysis of such cases and research are necessary...
  14. doi request reprint Analysis of lymph node metastasis in pancreatic neuroendocrine tumors (PNETs) based on the tumor size and hormonal production
    Kosuke Tsutsumi
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka, 812 8582, Japan
    J Gastroenterol 47:678-85. 2012
    ..This study aimed to evaluate the risk of lymph node metastasis of PNETs based on the tumor size and hormonal production...
  15. doi request reprint Bacterial DNA promotes proliferation of rat pancreatic stellate cells thorough toll-like receptor 9: potential mechanisms for bacterially induced fibrosis
    Taichi Nakamura
    Department of Medicine and Bioregulatory Science, Kyushu University, Fukuoka, Japan
    Pancreas 40:823-31. 2011
    ..We hoped to clarify the possible role of CpG DNA as a trigger factor for overt pancreatic inflammation of pancreatic stellate cells (PSCs)...
  16. ncbi request reprint Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity
    Junya Gibo
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Lab Invest 85:75-89. 2005
    ..However, procollagen alpha1 expression in PSCs was not influenced by CM. These results suggest that CM attenuated DBTC-induced rat pancreatic fibrosis via inhibition of monocytes and PSCs activity...
  17. doi request reprint Role of endoscopic retrograde pancreatography for early detection of pancreatic ductal adenocarcinoma concomitant with intraductal papillary mucinous neoplasm of the pancreas
    Takao Ohtsuka
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Hepatobiliary Pancreat Sci 20:356-61. 2013
    ..The aim of this study was to clarify whether endoscopic retrograde pancreatography (ERP) would be useful for the early detection of concomitant PDACs in patients with IPMNs...
  18. pmc Antithrombin III injection via the portal vein suppresses liver damage
    Masayuki Miyazaki
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    World J Gastroenterol 18:1884-91. 2012
    ..To investigate the effects of antithrombin III (AT III) injection via the portal vein in acute liver failure...
  19. ncbi request reprint A case of lipomatous pseudohypertrophy of the pancreas diagnosed by typical imaging
    Mikihiko Yasuda
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    JOP 11:385-8. 2010
    ..Lipomatous pseudohypertrophy of the pancreas is an extremely rare disease, and is characterized by the replacement of pancreatic acinar cells with adipose tissue, although the pancreatic duct and islets are preserved...
  20. doi request reprint ERK pathway and sheddases play an essential role in ethanol-induced CX3CL1 release in pancreatic stellate cells
    Masahiko Uchida
    Department of Medicine and Bioregulatory Science, Kyushu University, Fukuoka, Japan
    Lab Invest 93:41-53. 2013
    ..This might be one of the mechanisms of serum CX3CL1 elevation and disease progression in patients with alcoholic CP...
  21. ncbi request reprint IS-741 attenuates local migration of monocytes and subsequent pancreatic fibrosis in experimental chronic pancreatitis induced by dibutyltin dichloride in rats
    Toyoma Kaku
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pancreas 34:299-309. 2007
    ..In this study, we investigated whether IS-741 could inhibit the progression of pancreatic fibrosis through monocyte infiltration. Moreover, we investigated the effect of IS-741 on rat pancreatic stellate cells (PSCs)...
  22. doi request reprint Preserved gastric motility in patients with early gastric cancer after endoscopic submucosal dissection
    Naomi Higuchi
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Gastroenterol Hepatol 28:494-8. 2013
    ..To our knowledge, however, the functional effects of ESD have not been determined in patients with EGC. We therefore investigated whether gastric motility was affected by ESD...
  23. doi request reprint Intraductal papillary mucinous neoplasms of the pancreas with distinct pancreatic ductal adenocarcinomas are frequently of gastric subtype
    Noboru Ideno
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg 258:141-51. 2013
    ..To identify a high-risk group of patients with pancreatic ductal adenocarcinoma (PDAC), independently arising in the pancreas with intraductal papillary mucinous neoplasm (IPMN), using histopathologic subtypes...
  24. doi request reprint Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model
    Haruei Ogino
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol 47:366-76. 2012
    ..To provide rapid immunosuppression without side effects, we analyzed whether rapamycin alone, and regulatory T cells (Tregs) expanded ex vivo by rapamycin, suppressed colitis in a mouse model...
  25. doi request reprint Contrast-enhanced ultrasonography using Sonazoid to evaluate changes in hepatic hemodynamics in acute liver injury
    Masayuki Miyazaki
    Department of Medicine and Bioregulatory Science, Kyushu University, Japan
    J Gastroenterol Hepatol 26:1749-56. 2011
    ..Therefore, we investigated whether contrast-enhanced ultrasonography (CEUS) is useful to evaluate the changes in hepatic hemodynamics in patients with ALI...
  26. pmc Fractalkine and TGF-beta1 levels reflect the severity of chronic pancreatitis in humans
    Mikihiko Yasuda
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastroenterol 14:6488-95. 2008
    ..This study aimed at clarifying whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of CP...
  27. pmc PSCs and GLP-1R: occurrence in normal pancreas, acute/chronic pancreatitis and effect of their activation by a GLP-1R agonist
    Taichi Nakamura
    1 Department of Medicine and Bioregulatory Science, Kyushu University, Fukuoka, Japan 2 Department of Cell Biology Section, NIDDK, National Institutes of Health, Bethesda, MD, USA
    Lab Invest 94:63-78. 2014
    ..These results suggest chronic treatment with GLP-1R agonists could lead to proliferation/chronic activation of PSCs, which may lead to important effects in the pancreas. ..
  28. doi request reprint Treatment strategy for main duct intraductal papillary mucinous neoplasms of the pancreas based on the assessment of recurrence in the remnant pancreas after resection: a retrospective review
    Koji Tamura
    Departments of Surgery and Oncology Anatomic Pathology Clinical Radiology, and Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Surg 259:360-8. 2014
    ..To clarify the recurrence pattern after resection of main duct intraductal papillary mucinous neoplasms (MD-IPMNs) using molecular analyses and determine the most adequate treatment strategy...
  29. ncbi request reprint [A case of acute pancreatitis induced by metastasis of renal cell carcinoma]
    Junya Gibo
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
    Nihon Shokakibyo Gakkai Zasshi 100:901-6. 2003
  30. ncbi request reprint [A case of lymph node metastasis from esophageal small-cell-type endocrine cell carcinoma diagnosed by endoscopic ultrasound-guided fine-needle aspiration]
    Noriko Tokunaga
    Department of Medicine and Bioregulatory Science, Kyushu University, Japan
    Nihon Shokakibyo Gakkai Zasshi 109:1360-6. 2012
    ..He underwent EUS-guided fine-needle aspiration (FNA), and lymph node metastasis of small-cell-type endocrine cell carcinoma was diagnosed. He received VP-16 chemotherapy but died 22 months after the ESD...
  31. doi request reprint Prospective, randomized, double-blind, placebo-controlled trial of ulinastatin for prevention of hyperenzymemia after double balloon endoscopy via the antegrade approach
    Soichi Itaba
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University Hospital, Kyushu University, Fukuoka, Japan
    Dig Endosc 25:421-7. 2013
    ..Ulinastatin has been shown to be effective for the prevention of pancreatitis following endoscopic retrograde cholangiopancreatography. We therefore assessed the efficacy of ulinastatin for hyperenzymemia after antegrade DBE...
  32. pmc Endoscopic approach through the minor papilla for the management of pancreatic diseases
    Nao Fujimori
    Nao Fujimori, Hisato Igarashi, Akira Asou, Lingaku Lee, Takamasa Oono, Taichi Nakamura, Yusuke Niina, Masayuki Hijioka, Masahiko Uchida, Kazuhiro Kotoh, Kazuhiko Nakamura, Tetsuhide Ito, Ryoichi Takayanagi, Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastrointest Endosc 5:81-8. 2013
    ..To clarify the efficacy and safety of an endoscopic approach through the minor papilla for the management of pancreatic diseases...
  33. doi request reprint Relationship between pancreatic and/or extrapancreatic lesions and serum IgG and IgG4 levels in IgG4-related diseases
    Hisato Igarashi
    Department of Medicine and Bioregulatory Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Dig Dis 13:274-9. 2012
    ..We aimed to investigate the relationship between the number of involved organs or regions and serum immunoglobulin G (IgG) and immunoglobulin G4 (IgG4) levels...
  34. doi request reprint Follow-up study after resection of intraductal papillary mucinous neoplasm of the pancreas; special references to the multifocal lesions and development of ductal carcinoma in the remnant pancreas
    Takao Ohtsuka
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, Japan
    Am J Surg 204:44-8. 2012
    ..The aim of this study was to investigate the outcomes after resection of IPMNs, especially focusing on the metachronous occurrence of multifocal IPMNs and distinct PDACs...
  35. pmc The current strategy for managing pancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1
    Yusuke Niina
    Department of Medicine and Bioregulatory Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Gut Liver 6:287-94. 2012
    ..In addition, molecular-targeted drugs have recently been found to be effective in phase III clinical trials...
  36. pmc Cytosolic double-stranded DNA as a damage-associated molecular pattern induces the inflammatory response in rat pancreatic stellate cells: a plausible mechanism for tissue injury-associated pancreatitis
    Taichi Nakamura
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Int J Inflam 2012:504128. 2012
    ....
  37. doi request reprint Vasoactive intestinal peptide reduces oxidative stress in pancreatic acinar cells through the inhibition of NADPH oxidase
    Nao Fujimori
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    Peptides 32:2067-76. 2011
    ....
  38. doi request reprint Differential diagnosis of groove pancreatic carcinomas vs. groove pancreatitis: usefulness of the portal venous phase
    Kousei Ishigami
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Eur J Radiol 74:e95-e100. 2010
    ..To clarify if the portal venous phase is helpful for the differential diagnosis of groove pancreatic carcinomas and groove pancreatitis...
  39. ncbi request reprint Treatment for autoimmune pancreatitis: consensus on the treatment for patients with autoimmune pancreatitis in Japan
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Gastroenterol 42:50-8. 2007
    ....
  40. ncbi request reprint Adenocarcinoma involving the whole pancreas with multiple pancreatic masses
    Nao Fujimori
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka
    Intern Med 49:1527-32. 2010
    ..Incidentally, we also identified an adenocarcinoma of the common bile duct (CBD). The final diagnosis was synchronous double cancer involving the whole pancreas and the CBD...
  41. ncbi request reprint [Case of Zollinger-Ellison syndrome diagnosed three years after ulcer perforation in the third portion of the duodenum]
    Soichi Itaba
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
    Nihon Shokakibyo Gakkai Zasshi 105:705-10. 2008
    ..The tumor was extirpated and histologically found to be a neuroendocrine tumor in a lymph node. Serum gastrin level decreased to the normal range a day after surgery...
  42. doi request reprint Asian diagnostic criteria for autoimmune pancreatitis: consensus of the Japan-Korea Symposium on Autoimmune Pancreatitis
    Makoto Otsuki
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine, 1 1 Iseigaoka, Yahata nishi ku, Kitakyushu 807 8555, Japan
    J Gastroenterol 43:403-8. 2008
    ..A diagnostic trial of steroid therapy can be applied carefully by expert pancreatologists only in patients fulfilling criterion I alone with negative diagnostic work-up results for pancreatobiliary cancer...
  43. ncbi request reprint Pancreatic diabetes in a follow-up survey of chronic pancreatitis in Japan
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    J Gastroenterol 42:291-7. 2007
    ..We aimed to determine the cumulative rate of diabetes mellitus (DM) and the risk factors for DM in patients with chronic pancreatitis (CP) in Japan...
  44. pmc Lysophosphatidic acid induced nuclear translocation of nuclear factor-kappaB in Panc-1 cells by mobilizing cytosolic free calcium
    Yoshiyuki Arita
    Department of Medicine and Bioregulatory Science, Kyushu University, Fukuoka 812 8582, Japan
    World J Gastroenterol 14:4473-9. 2008
    ..To clarify whether Lysophosphatidic acid (LPA) activates the nuclear translocation of nuclear factor-kappaB (NF-kappaB) in pancreatic cancer...
  45. pmc Paclitaxel-based chemotherapy for advanced pancreatic cancer after gemcitabine-based therapy failure: a case series of 5 patients
    Hisato Igarashi
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka
    Case Rep Oncol 4:534-41. 2011
    ..We retrospectively analyzed the efficacy and adverse events, and evaluated the paclitaxel-containing regimens. A review of the literature is also discussed...
  46. pmc Chemoradiotherapy with twice-weekly administration of low-dose gemcitabine for locally advanced pancreatic cancer
    Hisato Igarashi
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastroenterol 14:5311-5. 2008
    ..To evaluate the chemoradiotherapy for locally advanced pancreatic cancer utilizing low dose gemcitabine as a radiation sensitizer administered twice weekly...
  47. pmc Pharmacotherapy of Zollinger-Ellison syndrome
    Tetsuhide Ito
    Kyushu University, Graduate School of Medical Sciences, Department of Medicine and Bioregulatory Science, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Expert Opin Pharmacother 14:307-21. 2013
    ..However, pharmacotherapy is also increasingly involved in the other management areas of these patients...
  48. doi request reprint Unresectable pancreatic ductal adenocarcinoma in the remnant pancreas diagnosed during every-6-month surveillance after resection of branch duct intraductal papillary mucinous neoplasm: a case report
    Koji Tamura
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University Fukuoka, Japan
    JOP 14:450-3. 2013
    ..Despite a strict surveillance protocol, some patients are diagnosed with metastatic distinct ductal adenocarcinoma after resection of IPMN...
  49. pmc Pancreatic neuroendocrine tumors: clinical features, diagnosis and medical treatment: advances
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Best Pract Res Clin Gastroenterol 26:737-53. 2012
    ..The other aspects of the management of these tumors (surgery, treatment of advanced disease, tumor localization) are not dealt with here, because they are covered in other chapters in this volume...
  50. doi request reprint Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas
    Teppei Aso
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Gastrointest Endosc 76:313-20. 2012
    ..A dilated orifice of the duodenal papilla found during screening endoscopy or ERCP is well-known as one of the specific findings of intraductal papillary mucinous neoplasm (IPMN). However, its clinical significance is still unclear...
  51. ncbi request reprint Expression and diagnostic evaluation of the human tumor-associated antigen RCAS1 in pancreatic cancer
    Tetsuro Akashi
    Department of Medicine, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    Pancreas 26:49-55. 2003
    ....
  52. doi request reprint An increase in the number of predictive factors augments the likelihood of malignancy in branch duct intraductal papillary mucinous neoplasm of the pancreas
    Takao Ohtsuka
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 151:76-83. 2012
    ..The aim of this study was to investigate whether increasing the number of predictive factors might augment the sensitivity of the established guidelines to detect malignant IPMNs...
  53. doi request reprint Low-frequency of bacteremia after endoscopic submucosal dissection of the stomach
    Soichi Itaba
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Dig Endosc 23:69-72. 2011
    ..Although bacteremia is reported as being infrequent and transient in gastric EMR, there are no reports of it being investigated in gastric ESD. This study aimed to determine the frequency of bacteremia in gastric ESD...
  54. ncbi request reprint The role of monocyte chemoattractant protein-1 in experimental chronic pancreatitis model induced by dibutyltin dichloride in rats
    Masanobu Inoue
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pancreas 25:e64-70. 2002
    ..Recently, dibutyltin dichloride (DBTC) was reported to induce pancreatic fibrosis within 28 days in rats, but it is not clear that the induced condition should be considered chronic pancreatitis...
  55. ncbi request reprint [Nutrition therapy for patients with chronic pancreatitis]
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
    Nihon Shokakibyo Gakkai Zasshi 104:1722-7. 2007
  56. ncbi request reprint Acute pancreatitis associated with peroral double-balloon enteroscopy: a case report
    Kuniomi Honda
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastroenterol 12:1802-4. 2006
    ..As his abdominal pain started after the procedure, his acute pancreatitis was thus thought to have been related to the peroral DBE. This is the first reported case of acute pancreatitis probably associated with peroral DBE...
  57. ncbi request reprint [A case of mediastinal pancreatic pseudocysts conservatively treated with somatostatin analogue]
    Tetsuro Akashi
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
    Nihon Shokakibyo Gakkai Zasshi 100:713-8. 2003
  58. pmc Gene expression levels as predictive markers of outcome in pancreatic cancer after gemcitabine-based adjuvant chemotherapy
    Hayato Fujita
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Neoplasia 12:807-17. 2010
    ..The aims of this study were to investigate the expression pattern of genes involved in gemcitabine sensitivity in resected PDAC tissues and to determine correlations of gene expression with treatment outcome...
  59. ncbi request reprint [Results of a nationwide survey of gastrointestinal tumors in Japan]
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Nihon Geka Gakkai Zasshi 109:128-32. 2008
    ..At present, the results of an epidemiologic investigation in 2005 in Japan are being analyzed, and the outcome of the survey in 2005 will be clarified in the very near future...
  60. ncbi request reprint The time course of gap-junctional protein connexin 32 expression in the pancreas after the induction of acute pancreatitis by caerulein in rats
    Keiichiro Ogoshi
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol 37:633-9. 2002
    ..The expression of Cx 32 in the pancreas during the course of acute pancreatitis is unclear. To address this, we examined Cx 32 mRNA and protein expression in the pancreas...
  61. ncbi request reprint [A case of postoperative recurrent gastric cancer resembling esophageal achalasia diagnosed by endoscopic ultrasound-guided fine-needle aspiration]
    Akira Asou
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
    Nihon Shokakibyo Gakkai Zasshi 107:1791-7. 2010
    ..Our experience suggests that EUS-FNA was useful for the histological diagnosis of recurrence of gastric cancer...
  62. ncbi request reprint [Pancreatic glucagon (IRG), enteroglucagon (EG)]
    Ken Kawabe
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
    Nihon Rinsho 63:493-5. 2005
  63. pmc Causes of death and prognostic factors in multiple endocrine neoplasia type 1: a prospective study: comparison of 106 MEN1/Zollinger-Ellison syndrome patients with 1613 literature MEN1 patients with or without pancreatic endocrine tumors
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Medicine (Baltimore) 92:135-81. 2013
    ....
  64. pmc Therapy of metastatic pancreatic neuroendocrine tumors (pNETs): recent insights and advances
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol 47:941-60. 2012
    ..Because of limited space, this review will be limited to the advances made in the management and treatment of patients with advanced metastatic pNETs over the past 5 years...
  65. ncbi request reprint Preliminary results of a Japanese nationwide survey of neuroendocrine gastrointestinal tumors
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Fukuoka, Japan
    J Gastroenterol 42:497-500. 2007
    ..We conducted a nationwide survey to estimate the incidence of neuroendocrine gastrointestinal tumors (NETs) newly diagnosed in Japan from 2002 through 2004...
  66. doi request reprint Nonmyeloablative allogeneic hematopoietic stem cell transplantation as immunotherapy for pancreatic cancer
    Yasunobu Abe
    Department of Medicine and Bioregulatory Science, Kyushu University, Fukuoka, Japan
    Pancreas 38:815-9. 2009
    ..Advanced unresectable pancreatic cancer has an extremely poor prognosis despite intensive chemotherapy. As a new therapeutic modality, we investigated nonmyeloablative allogeneic hematopoietic stem cell transplantation from a related donor...
  67. ncbi request reprint Consensus of primary care in acute pancreatitis in Japan
    Makoto Otsuki
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine, Kitakyushu, Japan
    World J Gastroenterol 12:3314-23. 2006
    ..The Japanese Government covers medical care expense for severe acute pancreatitis as one of the projects of Research on Measures for Intractable Diseases...
  68. ncbi request reprint Solid pancreatic hamartoma
    Shigenori Nagata
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pathol Int 57:276-80. 2007
    ..A search through the literature found only two cases of solid hamartoma of the pancreas, among the 14 cases previously reported as pancreatic hamartoma...
  69. ncbi request reprint Acetaminophen-induced acute pancreatitis. A case report
    Hisato Igarashi
    Department of Gastroenterology, National Hospital Organization, Beppu Medical Center, Beppu, Japan
    JOP 10:550-3. 2009
    ..More than 100 drugs have been implicated in causing the disease: acetaminophen has been associated with acute pancreatitis in cases where there has been an overdose of drugs; however, the frequency is rare...
  70. pmc Characteristics of hemorrhagic peptic ulcers in patients receiving antithrombotic/nonsteroidal antiinflammatory drug therapy
    Kazuhiko Nakamura
    Department of Medicine and Bioregulatory Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Gut Liver 6:423-6. 2012
    ..The features of hemorrhagic peptic ulcer disease in patients receiving antithrombotic/NSAID therapies were investigated...
  71. doi request reprint MRI findings of pancreatic lymphoma and autoimmune pancreatitis: a comparative study
    Kousei Ishigami
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Eur J Radiol 74:e22-8. 2010
    ..To clarify whether there are differences in MRI findings between pancreatic lymphomas and autoimmune pancreatitis (AIP)...
  72. ncbi request reprint Randomized controlled trial: roxatidine vs omeprazole for non-erosive reflux disease
    Kazuhiko Nakamura
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Hepatogastroenterology 57:497-500. 2010
    ..Since gastric acid secretion is lower in the Japanese population than in Western populations, we aimed to investigate whether PPI therapy is really necessary for NERD patients in Japan...
  73. pmc Diagnosis of Zollinger-Ellison syndrome: increasingly difficult
    Tetsuhide Ito
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    World J Gastroenterol 18:5495-503. 2012
    ..The clinical context of each of these important issues is reviewed and the conclusions in these articles commented from the perspective of clinical management...
  74. ncbi request reprint Can measurement of chemokines become useful biological and functional markers of early-stage chronic pancreatitis?
    Tetsuhide Ito
    Pancreas Diseases Branch, Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 5258, Japan
    J Gastroenterol 42:72-7. 2007
    ....
  75. doi request reprint Potential role of branched-chain amino acids in glucose metabolism through the accelerated induction of the glucose-sensing apparatus in the liver
    Nobito Higuchi
    Department of Medicine and Bioregulatory Science, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    J Cell Biochem 112:30-8. 2011
    ....
  76. ncbi request reprint Successful treatment of advanced-stage autoimmune pancreatitis-related sclerosing cholangitis
    Ken Kawabe
    Pancreas 33:434-7. 2006
  77. pmc Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal
    Kazuichi Okazaki
    The Third Department of Internal Medicine, Kansai Medical University, Moriguchi, Japan
    J Gastroenterol 41:626-31. 2006
  78. ncbi request reprint Acute pancreatitis in the early stages of pregnancy associated with a PSTI gene mutation
    Naoko Inoue
    Pancreas 29:242-3. 2004
  79. ncbi request reprint [Diagnosis and treatment of insulinoma]
    Yoshiyuki Arita
    Department of Medical and Bioregulatory Science, Graduate School of Medicine Science, Kyushu University
    Nihon Shokakibyo Gakkai Zasshi 101:359-66. 2004
  80. ncbi request reprint [A tumor of the pancreatic tail requiring differential diagnosis]
    Yubuko Noguchi
    Nihon Shokakibyo Gakkai Zasshi 105:99-100, 103. 2008
  81. ncbi request reprint Protective effects of rhubarb on experimental severe acute pancreatitis
    Yu Qing Zhao
    Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing 100730, China
    World J Gastroenterol 10:1005-9. 2004
    ..To investigate the effects of rhubarb on severe acute pancreatitis (SAP) in rats...