Research Topics
Species | Koji IkezoeSummaryAffiliation: Kyushu University Country: Japan Publications
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Detail Information
Publications
Amyloid-beta accumulation caused by chloroquine injections precedes ER stress and autophagosome formation in rat skeletal muscleKoji Ikezoe
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
Acta Neuropathol 117:575-82. 2009..Chloroquine-treated rats could be useful for investigating the pathogenesis of diseases related to Abeta accumulation...
Dysferlin expression in tubular aggregates: their possible relationship to endoplasmic reticulum stressKoji Ikezoe
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University 60, 812 8582, Fukuoka, Japan
Acta Neuropathol 105:603-9. 2003..Strong expression of dysferlin in TAs suggests the possibility that it is located not only at the sarcolemma but also in the SR, at least in the pathological conditions...
Ultrastructural detection of DNA fragmentation in myonuclei of fatal reducing body myopathyKoji Ikezoe
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University 60, 812 8582 Fukuoka, Japan
Acta Neuropathol 107:439-42. 2004..These results suggest that apoptosis takes part in muscle fiber degeneration in fatal reducing body myopathy, although the precise relationship between reducing bodies and apoptosis is uncertain...
Endoplasmic reticulum stress in myotonic dystrophy type 1 muscleKoji Ikezoe
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
Acta Neuropathol 114:527-35. 2007..Taken together, ER stress is involved in muscle wasting in DM1. However, it seems to be evoked not only by disrupted intracellular Ca2+ homeostasis...
[Case of eosinophilic myositis in continuum from localized nodular myositis]Dai Matsuse
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
Rinsho Shinkeigaku 48:36-42. 2008..As discussed, the involvement of eosinophils in three inflammatory myopathies was indicated...
Apoptosis is suspended in muscle of mitochondrial encephalomyopathiesKoji Ikezoe
Department of Neurology, Kyushu Koseinenkin Hospital, Kitakyushu, Fukuoka, 806-8501, Japan
Acta Neuropathol (Berl) 103:531-40. 2002..Sarcoplasmic expression of XIAP probably leads to the suspension of the apoptotic process in mitochondrial encephalomyopathies...
[An adulthood progressive case of congenital nemaline myopathy showing rimmed vacuoles in muscle biopsy and diffuse neurogenic changes on electromyography]Koji Ikezoe
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
Rinsho Shinkeigaku 44:450-3. 2004..Moreover, the presence of both nemaline rods and rimmed vacuoles may have contributed to the development of diffuse neurogenic changes seen in electromyography...
A unique case of fibrodysplasia ossificans progressiva with an ACVR1 mutation, G356D, other than the common mutation (R206H)Hirokazu Furuya
Department of Neurology, Neuro Muscular Center, National Omuta Hospital, Fukuoka, Japan
Am J Med Genet A 146:459-63. 2008..5-Mb region spanning ACVR1 and its neighbor genes suggested that 1067G > A is a de novo mutation. These results give a clue to better understanding of FOP as well as of the mild clinical symptoms in the patient...
[A patient with mitochondrial encephalomyopathy presenting gynecomastia with elevation of serum estriol level]Ryo Yamasaki
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
Rinsho Shinkeigaku 44:291-5. 2004..Thus, it is of potential that estrogens increased locally in muscle tissues of the patients with mitochondrial encephalomyopathies protect muscle fibers from oxidative damage due to mitochondrial dysfunction...
[Eosinophilic fasciitis associated with Borrelia afzelii infection]Osamu Kikuchi
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
Rinsho Shinkeigaku 44:299-302. 2004..Eosinophilic infiltration was absent. We treated the patient with prednisolone, doxycycline and amoxicillin, which alleviated the symptoms. This is the first report to show that Borrelia afzelii was involved in eosinophilic fasciitis...
Some flavonoids and DHEA-S prevent the cis-effect of expanded CTG repeats in a stable PC12 cell transformantHirokazu Furuya
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
Biochem Pharmacol 69:503-16. 2005..This system makes it easy to evaluate the toxic effects of expanded CTG repeats and therefore should be useful for screening other DM1 treatments for their efficacies...
Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's diseaseYasumasa Ohyagi
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
FASEB J 19:255-7. 2005....
[A family with autosomal dominant temporal lobe epilepsy accompanied by motor and sensory neuropathy]Takeshi Matsuoka
Department of Neurology, Graduate School of Medical Sciences, Kyushu University
Rinsho Shinkeigaku 44:43-9. 2004..Based on these data, we consider that this family to be a new phenotype of autosomal dominant TLE accompanied by motor and sensory neuropathy...
HTLV-1-associated myelopathy/tropical spastic paraparesis accompanied with psoriasisAkihiro Watanabe
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukoada 812-8582, Japan
J Neurol Sci 221:95-7. 2004..Although there are several reports indicating interferon-alpha induces or exacerbates psoriasis, our experience suggests that psoriasis associated with HAM/TSP can be successfully managed even during interferon-alpha therapy...
A case of dermato-fasciitis: amyopathic dermatomyositis associated with fasciitisYuko Tsuruta
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, 812 8582, Fukuoka, Japan
Clin Rheumatol 23:160-2. 2004..With steroid therapy, her symptoms and MRI abnormality disappeared within 2 months. This case is therefore considered to be a variant of ADM, presenting as dermato-fasciitis...
An improved method for Southern DNA and Northern RNA blotting using a Mupid-2 Mini-Gel electrophoresis unitHirokazu Furuya
Clinical Research Center, Japan
J Biochem Biophys Methods 68:139-43. 2006....
[The mechanism of skeletal muscle aging]Koji Ikezoe
Nippon Ronen Igakkai Zasshi 41:610-1. 2004
