Hideyuki Ikematsu

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. doi request reprint In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against influenza virus isolates in the 2011-2012 season in Japan
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, Japan Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 20:77-80. 2014
  2. doi request reprint The duration of fever and other symptoms after the initiation of laninamivir octanoate hydrate in the Japanese 2011-2012 influenza season
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, Japan Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 20:81-5. 2014
  3. pmc Evaluation of immune response following one dose of an AS03A-adjuvanted H1N1 2009 pandemic influenza vaccine in Japanese adults 65 years of age or older
    Hideyuki Ikematsu
    Hara Doi Hospital, Higashi ku, Fukuoka, Japan
    Hum Vaccin Immunother 8:1119-25. 2012
  4. pmc Characterization and long-term persistence of immune response following two doses of an AS03A-adjuvanted H1N1 influenza vaccine in healthy Japanese adults
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, Fukuoka, Japan
    Hum Vaccin Immunother 8:260-6. 2012
  5. doi request reprint In vitro neuraminidase inhibitory activities of four neuraminidase inhibitors against influenza viruses isolated in the 2010-2011 season in Japan
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Infect Chemother 18:529-33. 2012
  6. doi request reprint The post-infection outcomes of influenza and acute respiratory infection in patients above 50 years of age in Japan: an observational study
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, Fukuoka, Japan
    Influenza Other Respir Viruses 6:211-7. 2012
  7. ncbi request reprint Increased frequency of CD27- (naive) B cells and their phenotypic alteration in HIV type 1-infected patients
    Yong Chong
    Department of General Medicine, Kyushu University, Fukuoka 812 8582, Japan
    AIDS Res Hum Retroviruses 20:621-9. 2004
  8. ncbi request reprint CD27(+) (memory) B cell decrease and apoptosis-resistant CD27(-) (naive) B cell increase in aged humans: implications for age-related peripheral B cell developmental disturbances
    Yong Chong
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Int Immunol 17:383-90. 2005
  9. ncbi request reprint A comparison of the effectiveness of oseltamivir for the treatment of influenza A and influenza B: a Japanese multicenter study of the 2003-2004 and 2004-2005 influenza seasons
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 43:439-44. 2006
  10. doi request reprint Increased symptom severity but unchanged neuraminidase inhibitor effectiveness for A(H1N1)pdm09 in the 2010-2011 season: comparison with the previous season and with seasonal A(H3N2) and B
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, Tokyo, Japan
    Influenza Other Respir Viruses 7:448-55. 2013

Collaborators

Detail Information

Publications24

  1. doi request reprint In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against influenza virus isolates in the 2011-2012 season in Japan
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, Japan Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 20:77-80. 2014
    ..These results indicate that the currently epidemic influenza viruses are susceptible to all four neuraminidase inhibitors, with no trend for IC50 values to increase in Japan at present. ..
  2. doi request reprint The duration of fever and other symptoms after the initiation of laninamivir octanoate hydrate in the Japanese 2011-2012 influenza season
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, Japan Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 20:81-5. 2014
    ..These results show that laninamivir was effective for the treatment of both influenza A(H3N2) and B in this study, with no safety issues. The clinical effectiveness of laninamivir for A(H3N2) was superior to that for B. ..
  3. pmc Evaluation of immune response following one dose of an AS03A-adjuvanted H1N1 2009 pandemic influenza vaccine in Japanese adults 65 years of age or older
    Hideyuki Ikematsu
    Hara Doi Hospital, Higashi ku, Fukuoka, Japan
    Hum Vaccin Immunother 8:1119-25. 2012
    ....
  4. pmc Characterization and long-term persistence of immune response following two doses of an AS03A-adjuvanted H1N1 influenza vaccine in healthy Japanese adults
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, Fukuoka, Japan
    Hum Vaccin Immunother 8:260-6. 2012
    ..This could be beneficial in evaluating the importance and effect of vaccination with this AS03-adjuvanted pandemic influenza vaccine...
  5. doi request reprint In vitro neuraminidase inhibitory activities of four neuraminidase inhibitors against influenza viruses isolated in the 2010-2011 season in Japan
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Infect Chemother 18:529-33. 2012
    ..No isolate showed significantly high IC(50) values for zanamivir or laninamivir. Continuous surveillance against the emergence or spread of influenza virus with high IC(50) values for anti-influenza drugs is important...
  6. doi request reprint The post-infection outcomes of influenza and acute respiratory infection in patients above 50 years of age in Japan: an observational study
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, Fukuoka, Japan
    Influenza Other Respir Viruses 6:211-7. 2012
    ..The objective of this study was to estimate the prevalence and postinfection outcomes of influenza among the over-50 population in Japan...
  7. ncbi request reprint Increased frequency of CD27- (naive) B cells and their phenotypic alteration in HIV type 1-infected patients
    Yong Chong
    Department of General Medicine, Kyushu University, Fukuoka 812 8582, Japan
    AIDS Res Hum Retroviruses 20:621-9. 2004
    ..Some phenotypic alterations in CD27- B cells may continue after the reduction of HIV-1 loads by effective antiviral therapy...
  8. ncbi request reprint CD27(+) (memory) B cell decrease and apoptosis-resistant CD27(-) (naive) B cell increase in aged humans: implications for age-related peripheral B cell developmental disturbances
    Yong Chong
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Int Immunol 17:383-90. 2005
    ..These findings suggested that human aging leads to both quantitative and qualitative alterations in the peripheral B cell developmental system, including memory and naive B cell balance and their surface phenotypes...
  9. ncbi request reprint A comparison of the effectiveness of oseltamivir for the treatment of influenza A and influenza B: a Japanese multicenter study of the 2003-2004 and 2004-2005 influenza seasons
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 43:439-44. 2006
    ..The study included 3351 patients in whom influenza had been diagnosed by use of an antigen detection test kit...
  10. doi request reprint Increased symptom severity but unchanged neuraminidase inhibitor effectiveness for A(H1N1)pdm09 in the 2010-2011 season: comparison with the previous season and with seasonal A(H3N2) and B
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, Tokyo, Japan
    Influenza Other Respir Viruses 7:448-55. 2013
    ....
  11. ncbi request reprint Immunogenicity and safety of a novel AS03(A)-adjuvanted H1N1 2009 pandemic influenza vaccine in adults in Japan
    Hideyuki Ikematsu
    Hara Doi Hospital, Higashi ku, Fukuoka, Japan
    Hum Vaccin 6:888-93. 2010
    ..This study evaluated the immunogenicity and safety of a novel H1N1 2009 pandemic vaccine(A/California/7/2009) in Japanese adults...
  12. doi request reprint Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 49:1828-35. 2009
    ..Influenza A virus subtype H1N1 with the H274Y mutation emerged and spread worldwide. However, the clinical effectiveness of the neuraminidase inhibitors, oseltamivir and zanamivir, has not been adequately reevaluated...
  13. ncbi request reprint Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: a multicenter study from Japan of the 2002-2003 influenza season
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 40:1309-16. 2005
    ....
  14. ncbi request reprint Longer virus shedding in influenza B than in influenza A among outpatients treated with oseltamivir
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, Kanda Surugadai, Chiyoda ku, Tokyo, Japan
    J Infect 55:267-72. 2007
    ..To compare the persistence, susceptibility and resistance of influenza A and influenza B viruses in oseltamivir therapy in outpatients of various ages...
  15. ncbi request reprint Interferon-alpha/beta upregulate IL-15 expression in vitro and in vivo: analysis in human hepatocellular carcinoma cell lines and in chronic hepatitis C patients during interferon-alpha/beta treatment
    Kouzaburo Yamaji
    Department of General Medicine, Kyushu University Hospital, 3 3 1, Maidashi Higashiku, Fukuoka, 812 8582, Japan
    Cancer Immunol Immunother 55:394-403. 2006
    ..These results confirm that IFN-alpha/beta induce IL-15 production and also suggest that IL-15 may be associated with type I IFN-induced immune response...
  16. doi request reprint A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza
    Shigeki Nabeshima
    General Medicine, Fukuoka University Hospital, 7 45 1 Nanakuma, Jonan ku, Fukuoka, 814 0180, Japan
    J Infect Chemother 18:534-43. 2012
    ..The administration of oral maoto granules to healthy adults with seasonal influenza was well tolerated and associated with equivalent clinical and virological efficacy to neuraminidase inhibitors...
  17. doi request reprint Laninamivir octanoate: a new long-acting neuraminidase inhibitor for the treatment of influenza
    Hideyuki Ikematsu
    Department of Clinical Trials, Center for Advanced Medical Innovation, Kyushu University, 3 1 1 Maidashi Higashi ku, Fukuoka, Japan
    Expert Rev Anti Infect Ther 9:851-7. 2011
    ..Furthermore, this drug shows promise for the treatment of influenza in future pandemics...
  18. ncbi request reprint A prospective, Internet-based study of the effectiveness and safety of influenza vaccination in the 2001-2002 influenza season
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku 101 0062, Tokyo, Japan
    Vaccine 21:4507-13. 2003
    ..These results suggest that influenza vaccination is effective for children and adults and that a two-dose regimen is superior to a single dose in children 0-15 years...
  19. pmc Evaluation of influenza virus A/H3N2 and B vaccines on the basis of cross-reactivity of postvaccination human serum antibodies against influenza viruses A/H3N2 and B isolated in MDCK cells and embryonated hen eggs
    Noriko Kishida
    Laboratory of Influenza Virus Surveillance, Influenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Clin Vaccine Immunol 19:897-908. 2012
    ..The results of these human serological studies suggest that the influenza A/H3N2 vaccine for the 2010-2011 season and B vaccine for the 2009-2010 and 2010-2011 seasons may possess insufficient efficacy and low efficacy, respectively...
  20. ncbi request reprint A delayed type hypersensitivity (DTH) skin reaction to hepatitis B surface antigen (HBsAg) and intradermal hepatitis B vaccination
    Seiho Nagafuchi
    Department of Health Sciences, School of Medicine, Kyushu University, 812 8582, Japan
    Fukuoka Igaku Zasshi 95:305-13. 2004
    ..A similar vaccination strategy should prove to be useful in prevention and control of not only other infectious diseases but also malignant neoplasms...
  21. doi request reprint The relationship between the daily dosage of the carbapenem meropenem (MEPM) and MEPM-resistant Pseudomonas aeruginosa
    Shin ichi Harashima
    Department of Clinical Research, Hara Doi Hospital, Fukuoka, Japan
    J Infect Chemother 14:219-22. 2008
    ..aeruginosa in a hospital ward, and there were no side effects...
  22. doi request reprint Influence of oral health on febrile status in long-term hospitalized elderly patients
    Yoshihiro Shimazaki
    Department of Preventive Dentistry, Kyushu University Faculty of Dental Science, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Arch Gerontol Geriatr 48:411-4. 2009
    ..14, 95% CI=1.77-14.88. These results suggest that oral health status related to febrile status differs between dentate and edentate patients in the elderly population...
  23. ncbi request reprint Selective CD27+ (memory) B cell reduction and characteristic B cell alteration in drug-naive and HAART-treated HIV type 1-infected patients
    Yong Chong
    Department of General Medicine, Kyushu University, Fukuoka 812 8582, Japan
    AIDS Res Hum Retroviruses 20:219-26. 2004
    ....
  24. pmc Laninamivir octanoate for post-exposure prophylaxis of influenza in household contacts: a randomized double blind placebo controlled trial
    Seizaburo Kashiwagi
    Kashiwagi Clinic, SS Building Hakata Ekimae 4F, 3 21 15 Hakataekimae, Hakata Ku, Fukuoka, 812 0011, Japan
    J Infect Chemother 19:740-9. 2013
    ..The inhalation of 20 mg of laninamivir octanoate once daily for 2 or 3 days was well tolerated and effectively prevented the development of influenza in household contacts. ..