Takahiko Horiuchi

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. pmc Combined anteversion technique reduced the dislocation in cementless total hip arthroplasty
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan
    Int Orthop 38:27-32. 2014
  2. ncbi request reprint Results at a minimum of 10 years of follow-up for AMS and PerFix HA-coated cementless total hip arthroplasty: impact of cross-linked polyethylene on implant longevity
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, 1 3 3 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Orthop Sci 18:962-8. 2013
  3. doi request reprint Clinical and radiographic evaluation of total hip arthroplasties using porous tantalum modular acetabular components: 5-year follow-up of clinical trial
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, 1 3 3 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Mod Rheumatol 23:112-8. 2013
  4. ncbi request reprint Clinical evaluation of tocilizumab for patients with active rheumatoid arthritis refractory to anti-TNF biologics: tocilizumab in combination with methotrexate
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, Higashi ku, Fukuoka, Japan
    Mod Rheumatol 20:343-52. 2010
  5. doi request reprint Transtrochanteric rotational osteotomy for late-onset Legg-Calve-Perthes disease
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan
    J Pediatr Orthop 31:S223-8. 2011
  6. ncbi request reprint Cigarette smoking, STAT4 and TNFRSF1B polymorphisms, and systemic lupus erythematosus in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Rheumatol 36:2195-203. 2009
  7. doi request reprint Prevalence and risk factors of vertebral fracture in female Japanese patients with systemic lupus erythematosus
    Makio Furukawa
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Mod Rheumatol 23:765-73. 2013
  8. ncbi request reprint Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor alpha-expressing cells: comparison among infliximab, etanercept, and adalimumab
    Hiroki Mitoma
    Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Arthritis Rheum 58:1248-57. 2008
  9. ncbi request reprint Cigarette smoking, TP53 Arg72Pro, TP53BP1 Asp353Glu and the risk of lung cancer in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Oncol Rep 23:1361-8. 2010
  10. doi request reprint Cigarette smoking, alcohol consumption, and risk of systemic lupus erythematosus: a case-control study in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Rheumatol 39:1363-70. 2012

Detail Information

Publications40

  1. pmc Combined anteversion technique reduced the dislocation in cementless total hip arthroplasty
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan
    Int Orthop 38:27-32. 2014
    ..We examined whether the CA technique reduced the dislocation rate, and the distribution of CA with the manual placement of the cup...
  2. ncbi request reprint Results at a minimum of 10 years of follow-up for AMS and PerFix HA-coated cementless total hip arthroplasty: impact of cross-linked polyethylene on implant longevity
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, 1 3 3 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    J Orthop Sci 18:962-8. 2013
    ....
  3. doi request reprint Clinical and radiographic evaluation of total hip arthroplasties using porous tantalum modular acetabular components: 5-year follow-up of clinical trial
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, 1 3 3 Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Mod Rheumatol 23:112-8. 2013
    ..We present here 5-years follow-up report of a multicenter clinical trial of total hip arthroplasties (THA) with porous tantalum modular acetabular component (modular PTC)...
  4. ncbi request reprint Clinical evaluation of tocilizumab for patients with active rheumatoid arthritis refractory to anti-TNF biologics: tocilizumab in combination with methotrexate
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, Higashi ku, Fukuoka, Japan
    Mod Rheumatol 20:343-52. 2010
    ..Based on these results, we conclude that TCZ is able to significantly alleviate disease symptoms in a wide range of patients with RA in a normal clinical context...
  5. doi request reprint Transtrochanteric rotational osteotomy for late-onset Legg-Calve-Perthes disease
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan
    J Pediatr Orthop 31:S223-8. 2011
    ..The purpose of this study was to evaluate the long-term clinical results of the transtrochanteric rotational osteotomy for the patients with LCPD onset at more than 9 years of age...
  6. ncbi request reprint Cigarette smoking, STAT4 and TNFRSF1B polymorphisms, and systemic lupus erythematosus in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Rheumatol 36:2195-203. 2009
    ..Along with environmental factors such as smoking, both polymorphisms may modulate an individual's susceptibility to SLE. We investigated these relationships in a case-control study to evaluate risk factors for SLE among Japanese women...
  7. doi request reprint Prevalence and risk factors of vertebral fracture in female Japanese patients with systemic lupus erythematosus
    Makio Furukawa
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Mod Rheumatol 23:765-73. 2013
    ..We examined the prevalence and risk factors of vertebral fracture in female Japanese patients with systemic lupus erythematosus (SLE)...
  8. ncbi request reprint Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor alpha-expressing cells: comparison among infliximab, etanercept, and adalimumab
    Hiroki Mitoma
    Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Arthritis Rheum 58:1248-57. 2008
    ..We undertook this study to understand the different clinical effects of these anti-TNFalpha agents by analyzing their biologic activities on transmembrane TNFalpha...
  9. ncbi request reprint Cigarette smoking, TP53 Arg72Pro, TP53BP1 Asp353Glu and the risk of lung cancer in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Oncol Rep 23:1361-8. 2010
    ..Our findings indicate the possible association of the Glu allele of the TP53BP1 Asp353Glu polymorphism with lower risk of lung cancer especially among the Pro allele carriers of the TP53 Arg72Pro polymorphism...
  10. doi request reprint Cigarette smoking, alcohol consumption, and risk of systemic lupus erythematosus: a case-control study in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Rheumatol 39:1363-70. 2012
    ..Cigarette smoking may be associated with increased risk of systemic lupus erythematosus (SLE), whereas the role of alcohol consumption is unknown. We examined the association between SLE risk and smoking or drinking...
  11. ncbi request reprint Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections
    Yasutaka Kimoto
    Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Rheumatology (Oxford) 49:1346-53. 2010
    ..Identification of the association of killer cell immunoglobulin-like receptor (KIR) genes with SLE and accompanying infections...
  12. pmc Methylenetetrahydrofolate reductase polymorphisms and interaction with smoking and alcohol consumption in lung cancer risk: a case-control study in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    BMC Cancer 11:459. 2011
    ..We examined if smoking or alcohol consumption modify associations between MTHFR polymorphisms and lung cancer risk...
  13. doi request reprint The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α
    Naoyasu Ueda
    Department of Medicine and Biosystemic Science, Kyushu University, Graduate School of Medical Sciences, Fukuoka, Japan
    Inflamm Bowel Dis 19:1224-31. 2013
    ..This study investigated the cytotoxic effects of new anti-TNF-α agents, certolizumab pegol and golimumab, which are mediated by transmembrane TNF-α...
  14. doi request reprint Combination of TNF-RII, CYP1A1 and GSTM1 polymorphisms and the risk of Japanese SLE: findings from the KYSS study
    Takahiko Horiuchi
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Rheumatology (Oxford) 48:1045-9. 2009
    ..These three genes are involved in the generation of reactive oxygen species (ROS), which play a critical role for autoimmune diseases...
  15. ncbi request reprint Modifying effect of N-acetyltransferase 2 genotype on the association between systemic lupus erythematosus and consumption of alcohol and caffeine-rich beverages
    Chikako Kiyohara
    Kyushu University, Fukuoka, Japan
    Arthritis Care Res (Hoboken) 66:1048-56. 2014
    ..We investigated the effects of alcoholic and nonalcoholic caffeine-rich beverages on risk of SLE and determined whether the effects were modified by NAT2 status...
  16. ncbi request reprint Genetic polymorphisms involved in the inflammatory response and lung cancer risk: a case-control study in Japan
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan Electronic address
    Cytokine 65:88-94. 2014
    ..058). Future studies involving larger control and case populations will undoubtedly lead to a more thorough understanding of the role of the polymorphisms involved in the inflammation pathway in lung cancer. ..
  17. ncbi request reprint Remission in patients with active rheumatoid arthritis by tocilizumab treatment in routine clinical practice: results from 3 years of prospectively registered data
    Yasuharu Nakashima
    Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan
    Mod Rheumatol 24:258-64. 2014
    ..This study aimed to evaluate the remission in rheumatoid arthritis (RA) patients treated with tocilizumab (TCZ), based on prospectively registered data in clinical practice...
  18. doi request reprint Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus
    Makio Furukawa
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Rheumatol Int 31:365-76. 2011
    ..A history of high-dose oral corticosteroids was associated with the preservation of BMD at the lumbar spine, however, further study is needed considering the limited sample size...
  19. doi request reprint Genetic polymorphisms involved in carcinogen metabolism and DNA repair and lung cancer risk in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Japan
    J Thorac Oncol 7:954-62. 2012
    ..Several components of overall lung carcinogenesis, carcinogen metabolic and DNA repair pathways may be involved in individual genetic susceptibility to lung cancer...
  20. doi request reprint IL1B rs1143634 polymorphism, cigarette smoking, alcohol use, and lung cancer risk in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Thorac Oncol 5:299-304. 2010
    ..Interleukin 1B (IL1B) is involved in pulmonary inflammation induced by environmental or occupational toxins. Chronic inflammation has been implicated in the development of lung cancer...
  21. doi request reprint Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis: predominant reconstitution of Th1 CD4+ T cells
    Hiroshi Tsukamoto
    Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Rheumatology (Oxford) 50:944-52. 2011
    ..The aim of this study is to evaluate the mechanism of long-term effect of autologous haematopoietic stem cell transplantation (ASCT) in treatment of SSc...
  22. doi request reprint CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells
    Hiroaki Niiro
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Blood 119:2263-73. 2012
    ..Together, these results suggest that CIN85 is required for Cbl-mediated regulation of BCR signaling and for downstream events such as survival, growth, and differentiation of human B cells...
  23. ncbi request reprint Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus: molecular and functional analysis
    Junji Otsuka
    Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Arthritis Rheum 50:871-81. 2004
    ..To investigate whether polymorphism(s) or mutation(s) in the hematopoietic cell-specific Lyn substrate 1 (HS1) gene are involved in the pathogenesis of systemic lupus erythematosus (SLE)...
  24. ncbi request reprint Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus
    Hiroki Mitoma
    Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3 1 1, Maidashi, Higashi ku, Fukuoka City, Fukuoka 812 8582, Japan
    Int J Mol Med 16:609-15. 2005
    ..The abnormalities of IL-21R signaling might contribute to the pathological features of SLE, such as B lymphocytopenia...
  25. doi request reprint Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis
    Hidetake Yabuuchi
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Eur J Radiol 79:e74-9. 2011
    ....
  26. doi request reprint Cigarette smoking, N-acetyltransferase 2 polymorphisms and systemic lupus erythematosus in a Japanese population
    C Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Lupus 18:630-8. 2009
    ..50, 95% CI = 0.12-0.88), compared with the NAT2 rapid acetylator genotype and no history of smoking. This study suggests that, in this Japanese population, the NAT2 slow acetylator status may be a determinant in susceptibility to SLE...
  27. pmc Transmembrane TNF-alpha: structure, function and interaction with anti-TNF agents
    Takahiko Horiuchi
    Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Rheumatology (Oxford) 49:1215-28. 2010
    ....
  28. ncbi request reprint RP105-lacking B cells from lupus patients are responsible for the production of immunoglobulins and autoantibodies
    Yuji Kikuchi
    Saga Medical School, Saga, Japan
    Arthritis Rheum 46:3259-65. 2002
    ..In the present study, we attempted to determine whether RP105-negative B cells obtained from SLE patients would be capable of producing autoantibodies as well as immunoglobulins...
  29. ncbi request reprint Increased expression of membrane TNF-alpha on activated peripheral CD8+ T cells in systemic lupus erythematosus
    Takahiko Horiuchi
    Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka 812 8582, Japan
    Int J Mol Med 17:875-9. 2006
    ..038). Membrane TNF-alpha-bearing CD8+ T cells from SLE patients displayed cytotoxic activity against L929 cells. It is possible that membrane TNF-alpha may be involved in the increased apoptosis and the generation of autoantigens in SLE...
  30. ncbi request reprint Molecular bases for human complement C7 polymorphisms, C7*3 and C7*4
    Takahiko Horiuchi
    Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka 812 8582, Japan
    Biochem Biophys Res Commun 298:450-5. 2002
    ..We present genetic bases for this C7 polymorphism, which we determined using polymerase chain reaction (PCR)-based genotyping, a simple and accurate method suitable for large-scale studies...
  31. ncbi request reprint Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with systemic lupus erythematosus in Japanese
    Takahiko Horiuchi
    Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka 812 8582, Japan
    Int J Mol Med 14:813-8. 2004
    ..A larger scale of study will clarify whether these two mutations, T61I and R104Q, are associated with chronic inflammatory disorders, such as SLE, or not...
  32. ncbi request reprint Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus
    Hiroshi Tsukamoto
    Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka 812 8582, Japan
    Biochem Biophys Res Commun 330:298-304. 2005
    ..These data indicate that a novel AG-->GG 3'-splice acceptor site mutation in intron 38 caused aberrant splicing of exon 39, resulting in defective secretion of C3...
  33. pmc A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: a case-control study and a meta-analysis
    Takahiko Horiuchi
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Ann Rheum Dis 66:320-4. 2007
    ....
  34. ncbi request reprint Successful treatment of rapidly progressive interstitial pneumonia with autologous peripheral blood stem cell transplantation in a patient with dermatomyositis
    Kensuke Oryoji
    Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Higashi ku, Fukuoka, Japan
    Clin Rheumatol 24:637-40. 2005
    ..This improvement was confirmed by diminished interstitial shadows on chest X-ray and computed tomography scans. Eighteen months after transplantation, the patient is doing well without symptoms and signs of interstitial pneumonia...
  35. doi request reprint Hereditary angioedema in Japan: genetic analysis of 13 unrelated cases
    Tetsuro Yamamoto
    Yamamoto Clinic, Fukuoka, Japan
    Am J Med Sci 343:210-4. 2012
    ..Thus, the authors researched the genetic and clinical characteristics of Japanese patients with HAE...
  36. ncbi request reprint The relationship between the daily dosage of the carbapenem meropenem (MEPM) and MEPM-resistant Pseudomonas aeruginosa
    Shin ichi Harashima
    Department of Clinical Research, Hara Doi Hospital, Fukuoka, Japan
    J Infect Chemother 14:219-22. 2008
    ..aeruginosa in a hospital ward, and there were no side effects...
  37. doi request reprint Guideline for hereditary angioedema (HAE) 2010 by the Japanese Association for Complement Research - secondary publication
    Takahiko Horiuchi
    Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Allergol Int 61:559-62. 2012
    ..This is a 2010 year version and will be updated according to any pertinent medical advancements...
  38. ncbi request reprint Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha
    Hiroki Mitoma
    Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Gastroenterology 128:376-92. 2005
    ..To clarify this difference in clinical efficacy, we investigated reverse signaling through transmembrane TNF-alpha (mTNF) by these 2 anti-TNF agents...
  39. ncbi request reprint Reconstitution of HLA-A*2402-restricted cytomegalovirus-specific T-cells following stem cell transplantation
    Hisashi Gondo
    Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan
    Int J Hematol 80:441-8. 2004
    ....
  40. ncbi request reprint Systemic vasculitis associated with alphal-antitrypsin deficiency
    Yasushi Takii
    Department of Medicine and Biosystemic Science, Graduate School of Medical Science, Kyushu University, Fukuoka
    Intern Med 42:619-23. 2003
    ..This serious genetic defect severely affects the balance between a protease and a protease inhibitor at the pathological site...