Norihiro Furusyo

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. pmc Treatment for Eradication of Helicobacter pylori Infection among Chronic Hepatitis C Patients
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    Gut Liver 5:447-53. 2011
  2. ncbi request reprint Serum cholesterol and triglyceride reference ranges of twenty lipoprotein subclasses for healthy Japanese men and women
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan Electronic address
    Atherosclerosis 231:238-45. 2013
  3. doi request reprint Glycated albumin and diabetes mellitus
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan Electronic address
    Biochim Biophys Acta 1830:5509-14. 2013
  4. doi request reprint Plasma glycated albumin level and atherosclerosis: results from the Kyushu and Okinawa Population Study (KOPS)
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    Int J Cardiol 167:2066-72. 2013
  5. doi request reprint The serum undercarboxylated osteocalcin level and the diet of a Japanese population: results from the Kyushu and Okinawa Population Study (KOPS)
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, 3 1 1, Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Endocrine 43:635-42. 2013
  6. doi request reprint Ribavirin concentration in the later stages of 48 week pegylated interferon-alpha2b plus ribavirin therapy for chronic hepatitis C is useful for predicting virological response
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Antimicrob Chemother 66:1127-39. 2011
  7. doi request reprint Utility of glycated albumin for the diagnosis of diabetes mellitus in a Japanese population study: results from the Kyushu and Okinawa Population Study (KOPS)
    N Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, 3 1 1, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Diabetologia 54:3028-36. 2011
  8. pmc Excellent superiority and specificity of COBAS TaqMan HCV assay in an early viral kinetic change during pegylated interferon alpha-2b plus ribavirin treatment
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    BMC Gastroenterol 10:38. 2010
  9. ncbi request reprint Association between the treatment length and cumulative dose of pegylated interferon alpha-2b plus ribavirin and their effectiveness as a combination treatment for Japanese chronic hepatitis C patients: project of the Kyushu University Liver Disease Study
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka, Japan
    J Gastroenterol Hepatol 23:1094-104. 2008
  10. ncbi request reprint Clinical milestones for the prediction of severe anemia by chronic hepatitis C patients receiving telaprevir-based triple therapy
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Hepatol 59:667-74. 2013

Collaborators

Detail Information

Publications83

  1. pmc Treatment for Eradication of Helicobacter pylori Infection among Chronic Hepatitis C Patients
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    Gut Liver 5:447-53. 2011
    ..We determined the H. pylori carrier status and eradication rates of patients with chronic hepatitis C virus (HCV) infection...
  2. ncbi request reprint Serum cholesterol and triglyceride reference ranges of twenty lipoprotein subclasses for healthy Japanese men and women
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan Electronic address
    Atherosclerosis 231:238-45. 2013
    ..This epidemiological study was done to generate normal ranges for the cholesterol and triglyceride levels in serum lipoprotein subclasses isolated from healthy adults based on gender and menopausal status...
  3. doi request reprint Glycated albumin and diabetes mellitus
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan Electronic address
    Biochim Biophys Acta 1830:5509-14. 2013
    ..Diabetes is a growing worldwide problem that is strongly associated with atherosclerosis. Screening and intervention for diabetes in the earliest stages are advocated for the prevention of diabetic complications and cardiovascular disease...
  4. doi request reprint Plasma glycated albumin level and atherosclerosis: results from the Kyushu and Okinawa Population Study (KOPS)
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    Int J Cardiol 167:2066-72. 2013
    ..This study was done to test the hypothesis that GA can serve as a marker for atherosclerosis, similar to glycosylated hemoglobin A1c (HbA1c)...
  5. doi request reprint The serum undercarboxylated osteocalcin level and the diet of a Japanese population: results from the Kyushu and Okinawa Population Study (KOPS)
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, 3 1 1, Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Endocrine 43:635-42. 2013
    ..Our study indicates that the serum ucOC decreases with age in men, increases postmenopausally in women, and correlates inversely with dietary consumption of certain foods and with fasting glucose and HbA1c level...
  6. doi request reprint Ribavirin concentration in the later stages of 48 week pegylated interferon-alpha2b plus ribavirin therapy for chronic hepatitis C is useful for predicting virological response
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Antimicrob Chemother 66:1127-39. 2011
    ..This study was carried out to determine the relationship between ribavirin concentration in the later stages of treatment and virological relapse...
  7. doi request reprint Utility of glycated albumin for the diagnosis of diabetes mellitus in a Japanese population study: results from the Kyushu and Okinawa Population Study (KOPS)
    N Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, 3 1 1, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Diabetologia 54:3028-36. 2011
    ..We determined reference values for glycated albumin, and assessed its utility for the diagnosis of type 2 diabetes mellitus in the general population...
  8. pmc Excellent superiority and specificity of COBAS TaqMan HCV assay in an early viral kinetic change during pegylated interferon alpha-2b plus ribavirin treatment
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    BMC Gastroenterol 10:38. 2010
    ..To analyze an association between sustained virological response (SVR) and EVR by comparing TaqMan with Amplicor assays in HCV genotype 1-infected patients treated with pegylated (PEG)-IFN alpha-2b plus ribavirin (RBV)...
  9. ncbi request reprint Association between the treatment length and cumulative dose of pegylated interferon alpha-2b plus ribavirin and their effectiveness as a combination treatment for Japanese chronic hepatitis C patients: project of the Kyushu University Liver Disease Study
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka, Japan
    J Gastroenterol Hepatol 23:1094-104. 2008
    ....
  10. ncbi request reprint Clinical milestones for the prediction of severe anemia by chronic hepatitis C patients receiving telaprevir-based triple therapy
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Hepatol 59:667-74. 2013
    ..We herein evaluate the baseline and on-treatment predictors of the development of severe anemia by chronic hepatitis C virus (HCV) patients receiving TVR-based triple therapy...
  11. doi request reprint An inadequate dose of ribavirin is related to virological relapse by chronic hepatitis C patients treated with pegylated interferon alpha-2b and ribavirin
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Higashi ku, Fukuoka, 812 8582, Japan
    J Infect Chemother 18:689-97. 2012
    ..0088, respectively). To summarize, for HCV genotype 1 patients treated with PEG-IFNα-2b and RBV, the virological relapse of HCV was RBV dose-dependent, irrespective of the dose of PEG-IFNα or the effect of early viral kinetics...
  12. ncbi request reprint Insulin resistance undermines the advantages of IL28B polymorphism in the pegylated interferon alpha-2b and ribavirin treatment of chronic hepatitis C patients with genotype 1
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Hepatol 57:534-40. 2012
    ..We analyzed pretreatment factors useful for predicting sustained virological response (SVR), especially interleukin (IL) 28B polymorphism and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR)...
  13. doi request reprint Evaluation of the adverse effect of premature discontinuation of pegylated interferon α-2b and ribavirin treatment for chronic hepatitis C virus infection: results from Kyushu University Liver Disease Study
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Gastroenterol Hepatol 27:1233-40. 2012
    ..The aim of this study is to evaluate the reason for premature discontinuation during PEG-IFN α-2b and RBV treatment due to adverse effects in patients with chronic HCV infection...
  14. pmc Long-term lamivudine treatment for chronic hepatitis B in Japanese patients: a project of Kyushu University Liver Disease Study
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastroenterol 12:561-7. 2006
    ..To determine the efficacy of long-term lamivudine treatment of a large number of Japanese patients with chronic hepatitis B...
  15. pmc Interferon alpha plus ribavirin combination treatment of Japanese chronic hepatitis C patients with HCV genotype 2: a project of the Kyushu University Liver Disease Study Group
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastroenterol 12:784-90. 2006
    ..To determine the efficacy of an interferon alpha and ribavirin combination treatment for Japanese patients infected with hepatitis C virus (HCV) of genotype 2, a multi-center study was retrospectively analyzed...
  16. ncbi request reprint Efficacy of pegylated interferon alpha-2b and ribavirin treatment on the risk of hepatocellular carcinoma in patients with chronic hepatitis C: a prospective, multicenter study
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Hepatol 58:495-501. 2013
    ..This study investigated the impact of treatment outcome on the development of HCC by chronic hepatitis C patients treated with PegIFNα2b and RBV...
  17. doi request reprint Abbott RealTime PCR assay is useful for evaluating virological response to antiviral treatment for chronic hepatitis C
    Hiroaki Ikezaki
    Department of General Internal Medicine, Kyushu University Hospital, Higashi ku, Fukuoka 812 8582, Japan
    J Infect Chemother 17:737-43. 2011
    ..The relapse rate was lower when determined by ART than by CAM, but not significantly so. ART is more useful than CAM for evaluating the virological response to antiviral treatment for chronic hepatitis C...
  18. doi request reprint Telaprevir can be successfully and safely used to treat older patients with genotype 1b chronic hepatitis C
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Hepatol 59:205-12. 2013
    ..This study was performed to evaluate the efficacy of a triple therapy in older Japanese patients; telaprevir (TVR) was added to pegylated interferon α2b and ribavirin...
  19. doi request reprint Raloxifene hydrochloride is an adjuvant antiviral treatment of postmenopausal women with chronic hepatitis C: a randomized trial
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Hepatol 57:1186-92. 2012
    ....
  20. pmc Pegylated interferon α-2b plus ribavirin for older patients with chronic hepatitis C
    Mosaburo Kainuma
    Department of General Internal Medicine, Kyushu University Hospital, Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    World J Gastroenterol 16:4400-9. 2010
    ..To analyze the efficacy and safety of a combination therapy of pegylated interferon (PEG-IFN) α-2b plus ribavirin (RBV) in older Japanese patients (65 years or older) infected with hepatitis C virus (HCV)...
  21. ncbi request reprint Carotid atherosclerosis and cardiovascular risk factors: a comparison of residents of a rural area of Okinawa with residents of a typical suburban area of Fukuoka, Japan
    Masafumi Tatsukawa
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka 812 8582, Japan
    Atherosclerosis 172:337-43. 2004
    ..BMI was not a cardiovascular risk factor, although LDL cholesterol was a common important risk factor...
  22. doi request reprint Early phase viral kinetics of chronic hepatitis C patients receiving telaprevir-based triple therapy: a comparison of two real-time PCR assays
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    Antiviral Res 99:119-24. 2013
    ..In conclusion, a significant difference was found between the two real-time PCR assays for the assessment of virological response based on undetectable HCV RNA. ..
  23. ncbi request reprint The longitudinal quantitative assessment by transient elastography of chronic hepatitis C patients treated with pegylated interferon alpha-2b and ribavirin
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Higashi ku, Fukuoka, Japan
    Antiviral Res 83:127-34. 2009
    ..0270), and 48 weeks (P<0.0001) and 96 weeks (P<0.0001) after the end of treatment. The FibroScan values may predict a progressively better clinical outcome for patients with successful virological and biochemical responses...
  24. doi request reprint Protein-losing enteropathy during highly active antiretroviral therapy in a patient with AIDS-related disseminated Mycobacterial avium complex infection
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Higashi ku, Fukuoka, 812 8582, Japan
    J Infect Chemother 15:252-6. 2009
    ..In patients with AIDS, complete clinical remission of MAC (especially disseminated MAC) infection is very difficult...
  25. ncbi request reprint Association of hyperhomocysteinemia and Chlamydia pneumoniae infection with carotid atherosclerosis and coronary artery disease in Japanese patients
    Yasunori Sawayama
    Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Infect Chemother 14:232-7. 2008
    ..pneumoniae IgG positivity. These findings indicate that elevation of tHcy is related to positivity for anti-C. pneumoniae IgG in patients with CAD...
  26. ncbi request reprint Thymus and activation regulated chemokines in children with atopic dermatitis: Kyushu University Ishigaki Atopic Dermatitis Study (KIDS)
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka, 812 8582 Japan
    Eur J Dermatol 17:397-404. 2007
    ..1 pg/mL to 491.8 pg/mL). We demonstrated strong associations between TARC levels and the natural course of childhood AD. Monitoring serum TARC levels of AD children may be useful for the biological evaluation of AD...
  27. pmc Effect of laparoscopic splenectomy in patients with Hepatitis C and cirrhosis carrying IL28B minor genotype
    Takashi Motomura
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    BMC Gastroenterol 12:158. 2012
    ..However, the significance of these genetic variants in cirrhotic patients following splenectomy has not been determined...
  28. ncbi request reprint Double point mutation in the core promoter region of hepatitis B virus (HBV) genotype C may be related to liver deterioration in patients with chronic HBV infection
    Hisashi Nakashima
    Departments of Environmental Medicine and Infectious Disease, Faculty of Medical Sciences, Kyushu University Hospital, Higashi ku, Fukuoka 812 8582, Japan
    J Gastroenterol Hepatol 19:541-50. 2004
    ..We retrospectively investigated the relationship between HBV genotype and the core promoter (CP) (nt 1762 and 1764) and precore (PreC) (nt 1896) mutations of the HBV genome...
  29. ncbi request reprint Antibody to the human T-lymphotropic virus type 1 (HTLV-1) envelope protein Gp46 in patients co-infected with HCV and HTLV-1
    Hiroaki Takeoka
    Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    Am J Trop Med Hyg 77:192-6. 2007
    ..This antibody may be useful for the diagnosis of liver diseases and the development of more effective treatments...
  30. ncbi request reprint A prospective comparison of the effect of interferon-alpha and interferon-beta treatment in patients with chronic hepatitis C on the incidence of hepatocellular carcinoma development
    Kenichiro Kashiwagi
    Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Infect Chemother 9:333-40. 2003
    ..4% and 0.8%; P << 0.05), no significant difference was found in the IFN-beta group (6.3% and 2.3%). Similar rates of HCC development were found in patients with chronic HCV viremia treated with either IFN-alpha or IFN-beta...
  31. doi request reprint The association between fatal vascular events and risk factors for carotid atherosclerosis in patients on maintenance hemodialysis: plaque number of dialytic atherosclerosis study
    Shinji Maeda
    Department of Environmental Medicine and Infectious Diseases, Kyushu University, Fukuoka, Japan
    Atherosclerosis 204:549-55. 2009
    ..Moreover, PN was an independent marker of a fatal event, irrespective of DM status. Our results suggest that PN may be a useful predictor of the long-term prognosis of hemodialysis patients...
  32. pmc Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients
    Walaa H Ahmed
    Department of Environmental Medicine and Infectious Diseases, Kyushu University Hospital, Fukuoka 812 8582, Japan
    World J Gastroenterol 19:1387-95. 2013
    ..To investigate and clarify, for the first time, the role of inosine triphosphate pyrophosphatase (ITPA) polymorphism in Egyptian chronic hepatitis C virus (HCV) patients...
  33. doi request reprint Association between chronic hepatitis C virus infection and high levels of circulating N-terminal pro-brain natriuretic peptide
    Kyoko Okada
    Department of General Internal Medicine, Kyushu University Hospital, Maidashi, Fukuoka, 812 8582, Japan
    Endocrine 43:200-5. 2013
    ..005). Our data suggest that chronic HCV infection is associated with increased NT-proBNP, indicating that chronic HCV infection might induce myocardial dysfunction...
  34. pmc Long-term effects of lamivudine treatment in Japanese chronic hepatitis B patients
    Masayuki Murata
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, 812 8582, Japan
    World J Gastroenterol 17:2945-52. 2011
    ....
  35. ncbi request reprint Interferon-alpha/beta upregulate IL-15 expression in vitro and in vivo: analysis in human hepatocellular carcinoma cell lines and in chronic hepatitis C patients during interferon-alpha/beta treatment
    Kouzaburo Yamaji
    Department of General Medicine, Kyushu University Hospital, 3 3 1, Maidashi Higashiku, Fukuoka, 812 8582, Japan
    Cancer Immunol Immunother 55:394-403. 2006
    ..These results confirm that IFN-alpha/beta induce IL-15 production and also suggest that IL-15 may be associated with type I IFN-induced immune response...
  36. ncbi request reprint Confirmation of nosocomial hepatitis C virus infection in a hemodialysis unit
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka, Japan
    Infect Control Hosp Epidemiol 25:584-90. 2004
    ..To investigate a hepatitis C virus (HCV) outbreak in a hemodialysis unit and determine the source of transmission...
  37. ncbi request reprint Helper T cell cytokine response to ribavirin priming before combined treatment with interferon alpha and ribavirin for patients with chronic hepatitis C
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka 812 8582, Japan
    Antiviral Res 67:46-54. 2005
    ....
  38. ncbi request reprint Relationship of genotype rather than race to hepatitis B virus pathogenicity: a study of Japanese and Solomon Islanders
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Am J Trop Med Hyg 70:571-5. 2004
    ..5%) (P < 0.0001). These findings indicate that that HBV was of genotypes C and D in the Solomon Islands, and that the pathogenesis of HBV-infected patients is related to HBV genotype rather than race...
  39. doi request reprint Epidemiological study of hepatitis E virus infection in the general population of Okinawa, Kyushu, Japan
    Kazuhiro Toyoda
    Department of Environmental Medicine and Infectious Disease, Kyushu University, Fukuoka, Japan
    J Gastroenterol Hepatol 23:1885-90. 2008
    ..The aim of this study was to investigate the prevalence of hepatitis E virus (HEV) infection in the general population of Japan by determining presence of the antibody to HEV (anti-HEV)...
  40. ncbi request reprint Association factors for atopic dermatitis in nursery school children in Ishigaki islands - Kyushu University Ishigaki Atopic Dermatitis Study (KIDS)
    Noriko Fukiwake
    Department of Dermatology, Kyushu University Hospital, Maidashi 3 1 1, Higashiku, Fukuoka, Japan
    Eur J Dermatol 18:571-4. 2008
    ..A high total IgE level was a strong risk factor specific for atopic dermatitis in this population...
  41. ncbi request reprint [A case of AIDS-associated Kaposi's sarcoma with systemic invasion]
    Hiroaki Ikezaki
    Department of General Internal Medicine, Kyushu University Hospital
    Kansenshogaku Zasshi 85:54-8. 2011
    ..Despite the administration of pegylated liposomal doxorubicin (PLD) and highly active antiretroviral therapy, he died in disease progression, unable to complete PLD, KS-related respiratory failure...
  42. ncbi request reprint Influence of low-density lipoprotein cholesterol on virological response to telaprevir-based triple therapy for chronic HCV genotype 1b infection
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    Antiviral Res 104:102-9. 2014
    ..05). The baseline LDL-C level exerted a potent influence on the SVR of treatment-experienced patients treated with TVR-based triple therapy, especially for prior partial and null responders to PEG-IFNα and RBV...
  43. ncbi request reprint A case of successful hepatitis C virus eradication by 24 weeks of telaprevir-based triple therapy for a hemophilia patient with hepatitis C virus/human immunodeficiency virus co-infection who previously failed pegylated interferon-α and ribavirin therapy
    Masayuki Murata
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan Electronic address
    J Infect Chemother 20:320-4. 2014
    ..TVR can be used in combination with tenofovir, emtricitabine and raltegravir for patients with hemophilia. Furthermore, patients with undetectable HCV RNA at week 4 could be successfully treated with a 24-week regimen. ..
  44. doi request reprint Therapeutic drug monitoring of telaprevir in chronic hepatitis C patients receiving telaprevir-based triple therapy is useful for predicting virological response
    Norihiro Furusyo
    Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Antimicrob Chemother 69:483-90. 2014
    ....
  45. doi request reprint A population-based epidemiological survey of human parvovirus B19 infection: a project of the Kyushu and Okinawa Population Study (KOPS)
    Takeshi Ihara
    Department of Environmental Medicine and Infectious Diseases, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka, 812 8582, Japan
    Arch Virol 158:2465-72. 2013
    ..There is a risk of parvovirus B19 infection by blood transfusion from asymptomatic donors and that pregnant women are at high risk for parvovirus B19 infection. ..
  46. ncbi request reprint Clinical outcomes of hepatitis B virus (HBV) genotypes B and C in Japanese patients with chronic HBV infection
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Am J Trop Med Hyg 67:151-7. 2002
    ..These findings indicate that patients with HBV genotype C have more severe liver deterioration because of the delay of HBeAg disappearance and continued HBV replication after HBeAg disappearance...
  47. ncbi request reprint [Chronic infection is one of the etiologies for digestive diseases and atherosclerosis]
    Jun Hayashi
    Department of Medicine and Surgery, Faculty of Medical Sciences, Kyushu University, Department of General Medicine, Kyushu University Hospital
    Fukuoka Igaku Zasshi 99:67-73. 2008
  48. ncbi request reprint [A case of hepatitis B virus/human immunodeficiency virus coinfection in a patient who achived hepatitis B surface antigen seroclearance after interferon therapy followed by antiretroviral therapy without developing immune reconstitution inflammatory synd
    Fujiko Mitsumoto
    Department of General Internal Medicine, Kyushu University Hospital
    Kansenshogaku Zasshi 86:763-7. 2012
    ..The present case suggests that IFN therapy prior to ART contributes to a successful outcome for chronic hepatitis B patients coinfected with HIV, if the HIV status does not require the immediate start of ART...
  49. ncbi request reprint Strenuous physical labor is important as a cause of elevated alanine aminotransferase levels in Japanese patients with chronic hepatitis C viremia
    Norihiko Kubo
    Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    Eur J Epidemiol 20:251-61. 2005
    ..0001) was significantly associated with the elevated levels. These data suggests that strenuous physical labor over a long period of time might be related to elevated ALT levels in patients with chronic HCV viremia as well as drinking...
  50. doi request reprint A hypertriglyceridemic state increases high sensitivity C-reactive protein of Japanese men with normal glucose tolerance
    Kyoko Okada
    Department of General Internal Medicine, Kyushu University Hospital, Higashi ku, Fukuoka, 812 8582, Japan
    Endocrine 41:96-102. 2012
    ....
  51. ncbi request reprint Association of Chlamydophila pneumoniae DNA in peripheral blood mononuclear cells and IgA antibody with atherosclerotic diseases
    Yasunori Sawayama
    Department of General Medicine, Kyushu University, Fukuoka, Japan
    Fukuoka Igaku Zasshi 100:305-12. 2009
    ..18%, P < 0.05). Our results suggest that a high C. pneumoniae IgA antibody titer and C. pneumoniae DNA positivity are associated with an increased risk of atherosclerotic diseases due to endovascular C. pneumoniae infection...
  52. doi request reprint Longitudinal assessment of liver stiffness by transient elastography for chronic hepatitis B patients treated with nucleoside analog
    Eiichi Ogawa
    Department of General Internal Medicine, Kyushu University Hospital Department of Environmental Medicine and Infectious Disease, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hepatol Res 41:1178-88. 2011
    ....
  53. ncbi request reprint A comparison of the antitumor effects of interferon-alpha and beta on human hepatocellular carcinoma cell lines
    Masayuki Murata
    Department of Environmental Medicine and Infectious Disease, Internal Medicine, Faculty of Medical Science Kyushu University, and Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Cytokine 33:121-8. 2006
    ..These data suggest that IFN-beta has a greater antitumor effect than IFN-alpha on HCC of a very early stage in patients with chronic hepatitis C...
  54. doi request reprint The utility of urinary myo-inositol as a marker of glucose intolerance
    Hiroaki Ikezaki
    Department of Environmental Medicine and Infectious Disease, Kyushu University, Fukuoka, Japan
    Diabetes Res Clin Pract 103:88-96. 2014
    ..Because it reflects the current status of hyperglycemia, urinary myo-inositol (UMI) may be useful. We evaluated UMI as a screening tool for glucose intolerance...
  55. ncbi request reprint Carotid artery lesions and atherosclerotic risk factors in Japanese hemodialysis patients
    Naoyasu Maeda
    Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Atherosclerosis 169:183-92. 2003
    ..CA in the HD patients may be associated not only with several conventional risk factors but also with non-conventional risk factors such as phosphorus and the HD procedure itself...
  56. ncbi request reprint A patient in whom only hepatitis B virus (HBV) was thought to have been contracted, by kissing, from a same-sex partner coinfected with HBV and human immunodeficiency virus-1
    Norihiko Kubo
    Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Infect Chemother 9:260-4. 2003
    ..HBV infectivity was shown to be stronger than that of HIV in our patient, in whom only HBV was transmitted from a partner coinfected with HBV and HIV. This case highlights the importance of HBV as a sexually transmitted disease...
  57. ncbi request reprint Incidence of atopic dermatitis in nursery school children - a follow-up study from 2001 to 2004, Kyushu University Ishigaki Atopic Dermatitis Study (KIDS)
    Noriko Fukiwake
    Department of Dermatology, Kyushu University Hospital, Maidashi 3 1 1, Higashiku, 812 8582, Fukuoka, Japan
    Eur J Dermatol 16:416-9. 2006
    ..The regression rate of AD was > 70% while new-onset AD occurred at a rate of 3.67%/person year in nursery school children of Ishigaki Island...
  58. ncbi request reprint Effect on carotid atherosclerosis of probucol plus levofloxacin for Chlamydia pneumoniae infection
    Yasunori Sawayama
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka 812 8582, Japan
    J Infect Chemother 13:92-8. 2007
    ..01). These results suggest that the combination therapy was effective for improving carotid atherosclerosis in C. pneumoniae-seropositive patients...
  59. ncbi request reprint A decrease in mother-to-child transmission of human T lymphotropic virus type I (HTLV-I) in Okinawa, Japan
    Kenichiro Kashiwagi
    Department of Environmental Medicine and Infectious Disease, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    Am J Trop Med Hyg 70:158-63. 2004
    ..However, because the mother-to-child transmission rate among non-breast-feeders decreased from 12.8% in 1986-1991 to 3.2% in 1995-1999, there may be other factors involved in the decrease in mother-to-child transmission...
  60. ncbi request reprint Transient elastography for patients with chronic hepatitis B and C virus infection: Non-invasive, quantitative assessment of liver fibrosis
    Eiichi Ogawa
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Hepatol Res 37:1002-10. 2007
    ..559, P = 0.0093, and HCV, r = 0.686, P < 0.0001). Conclusion: These results suggest that FibroScan is an efficient and simple method for evaluating liver fibrosis in patients with chronic infection, both for HBV and HCV...
  61. doi request reprint Early extensive viremia, but not rs8099917 genotype, is the only predictor for cholestatic hepatitis C after living-donor liver transplantation
    Toru Ikegami
    Department of Surgery and Science, Kyushu University, Fukuoka, Japan
    Hepatol Res 43:621-9. 2013
    ..Cholestatic hepatitis C is one of the most serious but still unaddressed disorders after liver transplantation...
  62. ncbi request reprint The utility of visceral fat level by bioelectrical impedance analysis in the screening of metabolic syndrome - the results of the Kyushu and Okinawa Population Study (KOPS)
    Mami Unno
    Department of Environmental Medicine and Infectious Diseases, Kyushu University, Fukuoka, Japan
    J Atheroscler Thromb 19:462-70. 2012
    ..The aim of this study was to investigate the utility of VFL by BIA in the screening of metabolic syndrome (MetS)...
  63. ncbi request reprint Laparoscopic splenectomy with interferon therapy in 100 hepatitis-C-virus-cirrhotic patients with hypersplenism and thrombocytopenia
    Tomohiko Akahoshi
    Department of Surgery and Science, Kyushu University, Fukuoka, Japan
    J Gastroenterol Hepatol 27:286-90. 2012
    ..We intended to determine whether laparoscopic splenectomy (Lap-Sp) contributes to treatment with interferon therapy in hepatitis C virus (HCV)-cirrhotic patients with thrombocytopenia caused by hypersplenism...
  64. ncbi request reprint Prevalence of antibody to Chlamydia pneumoniae in residents of Japan, the Solomon Islands, and Nepal
    Chie Shimizu
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Am J Trop Med Hyg 67:170-5. 2002
    ..7% to 61.8% in the four difference areas of Japan. These findings indicate considerable differences in the prevalence of antibodies to C. pneumoniae by age in these nations and between the regions of Japan tested...
  65. ncbi request reprint Downregulation of CXCR5 in CD27- B cells of HIV-1 infected patients
    Yong Chong
    Department of General Medicine, Kyushu University Hospital, Higashiku, Fukuoka, Japan
    J Med Virol 73:362-7. 2004
    ..Impaired homing of naive B cells may contribute to HIV-1 induced immunological deficiencies...
  66. ncbi request reprint Prevalence and risk factors for diabetes: a ten year follow-up study of the Yaeyama district of Okinawa
    Kyoko Okada
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Fukuoka Igaku Zasshi 101:215-24. 2010
    ..Following BMI and systolic blood pressure is important...
  67. ncbi request reprint High molecular weight form of adiponectin levels of Japanese patients with chronic hepatitis C virus infection
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, and Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hepatol Res 37:1052-61. 2007
    ..Conclusion: It is possible that insulin resistance in patients with chronic HCV infection is related to adiponectin secretion...
  68. ncbi request reprint Inferior mesenteric arteriovenous fistula eight years after sigmoidectomy
    Kyoko Okada
    Department of Environmental Medicine and Infectious Disease, Faculty of Medical Sciences, Kyushu University, Fukuoka
    Intern Med 41:543-8. 2002
    ..Clinicians should be aware of the possibility of AVF in patients with a history of abdominal surgery...
  69. ncbi request reprint TT-virus infection in Japanese general population and in hemodialysis patients
    Yoko Kanamoto-Tanaka
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Dig Dis Sci 47:1915-20. 2002
    ....
  70. ncbi request reprint HIV infection with concomitant cerebral toxoplasmosis and disseminated histoplasmosis in a 45-year-old man
    Masayuki Murata
    Department of General Medicine, Kyushu University Hospital, 3 1 1 Maidashi, Fukuoka 812 8582, Japan
    J Infect Chemother 13:51-5. 2007
    ..This case highlights that histoplasmosis should be included in the differential diagnosis of opportunistic infections in AIDS patients when patients have a history of travel to or arrival from endemic areas...
  71. ncbi request reprint Intrafamilial transmission of Helicobacter pylori among the population of endemic areas in Japan
    Yayoi Fujimoto
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Helicobacter 12:170-6. 2007
    ..However, because many aspects concerning the route of transmission remain unclear, we performed this epidemiologic study to clarify the route of intrafamilial transmission of H. pylori...
  72. ncbi request reprint [Measures taken by a university hospital for the prevention and control of the 2009 H1N1 influenza]
    Jun Hayashi
    Department of General Internal Medicine, Kyushu University Hospital
    Nihon Rinsho 68:1707-12. 2010
    ..9%) were negative by influenza antigen test. Other 37 patients (5 adults, 32 children) were admitted, all of whom were successfully treated with neuraminidase inhibitors and discharged with no aftereffects...
  73. ncbi request reprint Intravenous immunoglobulin therapy for severe arthritis associated with human parvovirus B19 infection
    Eiichi Ogawa
    Department of General Medicine, Kyushu University Hospital, 3 1 1 Maidashi, Fukuoka, 812 8582, Japan
    J Infect Chemother 14:377-82. 2008
    ..Even in our immunocompetent patient, severe and prolonged arthritis was found to be associated with persistent viremia...
  74. doi request reprint Vigorous cleaning and adequate ventilation are necessary to control an outbreak in a neonatal intensive care unit
    Nobuyuki Shimono
    Department of Infection Control and Prevention Infection Control Team, Kyushu University Hospital, 3 1 1 Maidashi, Higashi ku, Fukuoka, Fukuoka 812 8582, Japan
    J Infect Chemother 18:303-7. 2012
    ..We need to pay more attention to these environmental factors in order to avoid cross contamination and infectious outbreaks...
  75. ncbi request reprint Relationship between body surface area and ALT normalization after long-term lamivudine treatment
    Makoto Nakamuta
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 5282, Japan
    World J Gastroenterol 11:6948-53. 2005
    ..To further evaluate the relationship between BSA and the effects of lamivudine in a greater number of cases and over a longer period of observation than in our previous evaluation...
  76. ncbi request reprint Serum antibody response to tuberculosis-associated glycolipid antigen after BCG vaccination in adults
    Shigeki Nabeshima
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Infect Chemother 11:256-8. 2005
    ..These results showed that serological diagnosis using anti-TBGL antibody was not influenced by prior BCG vaccination...
  77. ncbi request reprint A Japanese case of severe refractory adult Still's disease: serum interleukin-18 is a possible marker of the response to low-dose cyclosporin A therapy
    Yasunori Sawayama
    Department of General Medicine, Kyushu University Hospital, Higashi ku, Fukuoka 812 8582, Japan
    Fukuoka Igaku Zasshi 93:189-95. 2002
    ..The serum interleukin-18 level was monitored throughout treatment and was found to be a potentially useful marker of disease activity as well as of the response to cyclosporin A therapy...
  78. ncbi request reprint Antibody response to influenza vaccine in adults vaccinated with identical vaccine strains in consecutive years
    Shigeki Nabeshima
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Med Virol 79:320-5. 2007
    ..These results suggest that the decreased HI antibody response to repeated influenza vaccination was affected mainly by the previous vaccination per se rather than by the pre-existing antibody titer...
  79. ncbi request reprint Prevalence of atopic dermatitis and serum IgE values in nursery school children in Ishigaki Island, Okinawa, Japan
    Maki Hamada
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    J Dermatol 32:248-55. 2005
    ..The Japanese translated form of the questionnaire of the U.K. Working Party diagnostic criteria for AD should be refined to improve its sensitivity...
  80. ncbi request reprint A patient with primary human immunodeficiency virus infection for whom highly active antiretroviral therapy was successful
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Infect Chemother 8:361-4. 2002
    ..The patient has remained asymptomatic for the 18 months since symptom resolution after HAART, and HIV-1 RNA remains undetectable...
  81. ncbi request reprint Amelioration of extrapontine myelinolysis and reversible parkinsonism in a patient with asymptomatic hypopituitarism
    Kyoko Okada
    Department of General Medicine, Kyushu University Hospital, Fukuoka
    Intern Med 44:739-42. 2005
    ....
  82. ncbi request reprint Chronic myelogenous leukemia that occurred two years after the diagnosis of adult Still's disease
    Yoshifumi Nakagawa
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Intern Med 44:994-7. 2005
    ..No case of CML was reported to develop from ASD. Because a diagnosis of ASD is based on the exclusion of other diseases, we must be cognizant of the possibility of the development of concurrent diseases...
  83. ncbi request reprint Hepatitis C virus (HCV) RNA level determined by second-generation branched-DNA probe assay as predictor of response to interferon treatment in patients with chronic HCV viremia
    Norihiro Furusyo
    Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan
    Dig Dis Sci 47:535-42. 2002
    ..0 Meq/ml was the most favorable marker of successful IFN treatment and that patients with genotype 2a, even those with level >1.0 Meq/ml, had a high rate of SR to IFN treatment...