T Arima

Summary

Affiliation: Kyushu University
Country: Japan

Publications

  1. ncbi request reprint The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice
    Takahiro Arima
    Division of Molecular and Cell Therapeutics, Department of Molecular Genetics, Kyusyu University, Beppu, Oita 874 0838, Japan
    Genomics 88:650-8. 2006
  2. ncbi request reprint Loss of the maternal imprint in Dnmt3Lmat-/- mice leads to a differentiation defect in the extraembryonic tissue
    Takahiro Arima
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyusyu University, Beppu, Oita 874 0838, Japan
    Dev Biol 297:361-73. 2006
  3. ncbi request reprint Establishment of the primary imprint of the HYMAI/PLAGL1 imprint control region during oogenesis
    T Arima
    Division of Molecular and Cell Therapeutics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyusyu University, Kyusyu, Japan
    Cytogenet Genome Res 113:247-52. 2006
  4. ncbi request reprint Expression of DCC and netrin-1 in normal human endometrium and its implication in endometrial carcinogenesis
    H D Kato
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyushu University, Beppu City, Oita 874 0838, Japan
    Gynecol Oncol 95:281-9. 2004
  5. ncbi request reprint The correlation between the clinical laboratory data and the telomere length in peripheral blood leukocytes of Japanese female patients with hypertension
    T Maeda
    The Division of Molecular and Clinical Gerontology, Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Oita, 874 0838, Japan
    J Nutr Health Aging 15:240-4. 2011
  6. ncbi request reprint Growth-associated gene expression profiles by microarray analysis of trophoblast of molar pregnancies and normal villi
    H D Kato
    Division of Molecular and Cell Therapeutics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Beppu City, Oita, Japan
    Int J Gynecol Pathol 21:255-60. 2002
  7. ncbi request reprint Involvement of mutations in the DPC4 promoter in endometrial carcinoma development
    Y Zhou
    Department of Reproductive Physiology and Endocrinology, Medical Institute of Bioregulation, Kyushu Univeristy, Beppu, Oita, Japan
    Mol Carcinog 25:64-72. 1999
  8. ncbi request reprint The correlation between the telomeric parameters and the clinical laboratory data in the patients with brain infarct and metabolic disorders
    T Maeda
    Division of Molecular and Clinical Gerontology, Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Oita, Japan
    J Nutr Health Aging 14:793-7. 2010
  9. ncbi request reprint Epigenetic silencing of the imprinted gene ZAC by DNA methylation is an early event in the progression of human ovarian cancer
    Tetsuya Kamikihara
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyusyu University, Oita, Japan
    Int J Cancer 115:690-700. 2005
  10. ncbi request reprint Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients
    Hisato Kobayashi
    Department of Obstetrics, Tohoku University Graduate School of Medicine, 2 1 Seiryo cho, Aoba ku, Sendai 980 8575, Japan
    Hum Mol Genet 16:2542-51. 2007

Collaborators

Detail Information

Publications19

  1. ncbi request reprint The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice
    Takahiro Arima
    Division of Molecular and Cell Therapeutics, Department of Molecular Genetics, Kyusyu University, Beppu, Oita 874 0838, Japan
    Genomics 88:650-8. 2006
    ..Therefore, we propose that this DMR functions as the IC for the HYMAI/PLAGL1 domain...
  2. ncbi request reprint Loss of the maternal imprint in Dnmt3Lmat-/- mice leads to a differentiation defect in the extraembryonic tissue
    Takahiro Arima
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyusyu University, Beppu, Oita 874 0838, Japan
    Dev Biol 297:361-73. 2006
    ..These findings provide evidence that not only is DNA methylation required for the appropriate maternal imprint in the placenta but that the appropriate imprint is absolutely required for vertebrate placentation...
  3. ncbi request reprint Establishment of the primary imprint of the HYMAI/PLAGL1 imprint control region during oogenesis
    T Arima
    Division of Molecular and Cell Therapeutics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyusyu University, Kyusyu, Japan
    Cytogenet Genome Res 113:247-52. 2006
    ....
  4. ncbi request reprint Expression of DCC and netrin-1 in normal human endometrium and its implication in endometrial carcinogenesis
    H D Kato
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyushu University, Beppu City, Oita 874 0838, Japan
    Gynecol Oncol 95:281-9. 2004
    ..To define these roles more clearly, we examined the expression of DCC and its ligand, netrin-1, in the normal endometrium and in endometrial cancer...
  5. ncbi request reprint The correlation between the clinical laboratory data and the telomere length in peripheral blood leukocytes of Japanese female patients with hypertension
    T Maeda
    The Division of Molecular and Clinical Gerontology, Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Oita, 874 0838, Japan
    J Nutr Health Aging 15:240-4. 2011
    ....
  6. ncbi request reprint Growth-associated gene expression profiles by microarray analysis of trophoblast of molar pregnancies and normal villi
    H D Kato
    Division of Molecular and Cell Therapeutics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Beppu City, Oita, Japan
    Int J Gynecol Pathol 21:255-60. 2002
    ..Genes identified in this study may elucidate regulation mechanisms of trophoblastic proliferation and mechanisms causing a pathological phenotype in CMs...
  7. ncbi request reprint Involvement of mutations in the DPC4 promoter in endometrial carcinoma development
    Y Zhou
    Department of Reproductive Physiology and Endocrinology, Medical Institute of Bioregulation, Kyushu Univeristy, Beppu, Oita, Japan
    Mol Carcinog 25:64-72. 1999
    ..Chloramphenicol acetyltransferase assays clearly demonstrated that the mutant promoters had the potential to suppress or silence DPC4 transcription, implicating the DPC4 gene in endometrial carcinoma...
  8. ncbi request reprint The correlation between the telomeric parameters and the clinical laboratory data in the patients with brain infarct and metabolic disorders
    T Maeda
    Division of Molecular and Clinical Gerontology, Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Oita, Japan
    J Nutr Health Aging 14:793-7. 2010
    ..This is the first report describing a link between routine clinical laboratory data and genomic aging...
  9. ncbi request reprint Epigenetic silencing of the imprinted gene ZAC by DNA methylation is an early event in the progression of human ovarian cancer
    Tetsuya Kamikihara
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyusyu University, Oita, Japan
    Int J Cancer 115:690-700. 2005
    ..Supplementary material for this article can be found on the International Journal of Cancer website at http://www.interscience.wiley.com/jpages/0020-7136/suppmat/index.html.)..
  10. ncbi request reprint Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients
    Hisato Kobayashi
    Department of Obstetrics, Tohoku University Graduate School of Medicine, 2 1 Seiryo cho, Aoba ku, Sendai 980 8575, Japan
    Hum Mol Genet 16:2542-51. 2007
    ..Our data suggest that sperm from infertile patients, especially those with oligospermia, may carry a higher risk of transmitting incorrect primary imprints to their offspring, highlighting the need for more research into ART...
  11. ncbi request reprint Characterization of side-population cells in human normal endometrium
    Kiyoko Kato
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyushu University, Higashi ku, Fukuoka, Japan
    Hum Reprod 22:1214-23. 2007
    ..In this study, we isolated SP cells from the human endometrium and analysed their properties...
  12. ncbi request reprint Contribution of estrogen receptor alpha to oncogenic K-Ras-mediated NIH3T3 cell transformation and its implication for escape from senescence by modulating the p53 pathway
    Kiyoko Kato
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics Medical Institute of Bioregulation, Kyushu University, Tsurumihara 4546, Beppu, Oita, Japan
    J Biol Chem 277:11217-24. 2002
    ..The data imply that the ERalpha-AP1 pathway activated by oncogenic K-Ras 4B mutant contributes to the NIH3T3 cells' transformation by modulating p53 transcriptional activity through MDM2...
  13. ncbi request reprint Novel conserved elements upstream of the H19 gene are transcribed and act as mesodermal enhancers
    Robert A Drewell
    Wellcome CRC Institute of Cancer and Developmental Biology and Physiological Laboratory, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    Development 129:1205-13. 2002
    ..We propose that these novel sequences interact with the ICR at H19 and the epigenetically regulated silencer at differentially methylated region 1 (DMR1) of Igf2...
  14. ncbi request reprint Identification of FOXC1 as a TGF-beta1 responsive gene and its involvement in negative regulation of cell growth
    Yong Zhou
    Division of Molecular and Cell Therapeutics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumihara, Beppu, Oita, 874 0838, Japan
    Genomics 80:465-72. 2002
    ..7% of primary cancers. Evidence that a significant fraction of primary cancers exhibited somatic mutations suggests that FOXC1 functions as a tumor suppressor through TGF-beta1 mediated signals...
  15. ncbi request reprint K-Ras and H-Ras activation promote distinct consequences on endometrial cell survival
    Yumiko Ninomiya
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyushu University, Oita, Japan
    Cancer Res 64:2759-65. 2004
    ..Coordination of the two pathways contributes to endometrial cell survival...
  16. ncbi request reprint Expression of progesterone receptor B is associated with G0/G1 arrest of the cell cycle and growth inhibition in NIH3T3 cells
    Shinji Horiuchi
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyushu University, Tsurumihara 4546, Beppu, Oita, 874 0838, Japan
    Exp Cell Res 305:233-43. 2005
    ..Finally, we showed that PR-B modulation involved in the regulation of NIH3T3 cell proliferation was independent of nuclear estrogen receptor (ER) activity but dependent on non-genomic ER activity...
  17. pmc ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome
    Takahiro Arima
    Department of Reproductive Physiology and Endocrinology, Medical Institute of Bioregulation, Kyusyu University 4546, Tsurumihara, Beppu, Oita 874 0838, Japan
    Nucleic Acids Res 33:2650-60. 2005
    ..Mutations in ZAC may, therefore, contribute to Beckwith-Wiedemann syndrome. Furthermore, we find changes in DNA methylation at the LIT1 putative imprinting control region in two patients with TNDB...
  18. ncbi request reprint An inhibitory effect on cell proliferation by blockage of the MAPK/estrogen receptor/MDM2 signal pathway in gynecologic cancer
    Shin Suga
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Medical Institute of Bioregulation, Kyushu University, Maidadhi 3 1 1, Higashi ku, Fukuoka, Japan
    Gynecol Oncol 105:341-50. 2007
    ..We previously demonstrated that that the Ras/ER/MDM2 pathway was critical for NIH3T3 cell transformation. In this study, we examined the effect of blocking this pathway on cell growth in gynecologic cancer cells...
  19. ncbi request reprint Specific apoptosis induction in human papillomavirus-positive cervical carcinoma cells by photodynamic antisense regulation
    Asako Yamayoshi
    Department of Molecular Genetics, Division of Molecular and Cell Therapeutics, Kyushu University, Maidashi, Fukuoka 812 8582, Japan
    Oligonucleotides 17:66-79. 2007
    ..These results suggest that the photodynamic antisense strategy has the great therapeutic potential in HPV-positive cervical cancers...