Research Topics
Species | Y AbeSummaryAffiliation: Kyushu University Country: Japan Publications
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Detail Information
Publications
Subcutaneous panniculitis by Epstein-Barr virus-infected natural killer (NK) cell proliferation terminating in aggressive subcutaneous NK cell lymphomaY Abe
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Am J Hematol 64:221-5. 2000..This suggests that chronic EB virus infections play an important role in the early stages of tumorigenesis and in the progression of NK cell lymphoproliferative disorders...
Expression of apoptosis-associated protein RCAS1 in macrophages of histiocytic necrotizing lymphadenitisYasunobu Abe
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Int J Hematol 77:359-63. 2003..0002; paired t test). Our findings suggest that RCAS1 expressed on macrophages may play an important role in the induction of activated T-cell apoptosis in cases of HNL...
Eradication of virus-infected T-cells in a case of adult T-cell leukemia/lymphoma by nonmyeloablative peripheral blood stem cell transplantation with conditioning consisting of low-dose total body irradiation and pentostatinYasunobu Abe
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Int J Hematol 76:91-3. 2002..This fact indicates that eradication of ATL cells is feasible by induction of an alloimmune response without high-dose chemoradiotherapy...
Adult onset cyclic hematopoiesis in a patient with myelodysplastic syndromeY Abe
Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Int J Hematol 71:40-5. 2000..The percentage of CD3-positive cells oscillated inversely, suggesting that the cyclic cytopenia had an immune mechanism involving T lymphocytes...
Nonmyeloablative allogeneic hematopoietic stem cell transplantation as immunotherapy for pancreatic cancerYasunobu Abe
Department of Medicine and Bioregulatory Science, Kyushu University, Fukuoka, Japan
Pancreas 38:815-9. 2009..Advanced unresectable pancreatic cancer has an extremely poor prognosis despite intensive chemotherapy. As a new therapeutic modality, we investigated nonmyeloablative allogeneic hematopoietic stem cell transplantation from a related donor...
Cytotoxic T-cell lymphoma diffusely involving the entire gastrointestinal tract associated with Epstein-Barr virus and tubercle bacilli infectionY Abe
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Int J Hematol 71:379-84. 2000..We present here an interesting case of gastrointestinal cytotoxic T-cell lymphoma and examine the possible association with infectious agents...
Autoimmune neutropenia with cyclic oscillation of neutrophil count after steroid administrationN Hirase
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Int J Hematol 73:346-50. 2001..Following splenectomy, neutrophil and platelet counts normalized. We believe the immune mechanism of recurrent neutropenia in this patient differs from that in other patients with cyclic neutropenia reported with stem cell disorders...
[Two cases of B cell lymphoma associated with hemophagocytic syndrome]Y Abe
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
Rinsho Ketsueki 42:35-40. 2001..At autopsy, there was no evidence of IVL. Both of these patients showed high fever and cytopenia, and the disease took an aggressive clinical course, as in other reported cases of B-LAHS...
Role of NF-kappa B in regulation of apoptosis of erythroid progenitor cellsN Sae-Ung
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
Eur J Haematol 74:315-23. 2005....
Macrophage inflammatory protein 1alpha enhances in a different manner adhesion of hematopoietic progenitor cells from bone marrow, cord blood, and mobilized peripheral bloodY Suehiro
Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Oita, Japan
Exp Hematol 27:1637-45. 1999..Our data indicate that MIP-1alpha may affect migration, homing, and mobilization of hematopoietic progenitors by modulating the adhesive phenotype of these cells...
Receptor binding cancer antigen expressed on SiSo cells, a novel regulator of apoptosis of erythroid progenitor cellsT Matsushima
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
Blood 98:313-21. 2001....
Interleukin-6 sensitizes multiple myeloma cell lines for apoptosis induced by interferon-alphaR Minami
Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Exp Hematol 28:244-55. 2000....
Hemophagocytic syndrome: a rare complication of allogeneic nonmyeloablative hematopoietic stem cell transplantationY Abe
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Bone Marrow Transplant 29:799-801. 2002....
An amplification of IL-10 and TGF-beta in patients with IgG4-related tubulointerstitial nephritisH Nakashima
Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
Clin Nephrol 73:385-91. 2010....
Aberrant BCR-ABL transcript with intronic insertion in a patient with philadelphia chromosome-positive chronic myeloid leukemia: implications for disease progressionM Shiratsuchi
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Leuk Lymphoma 41:411-5. 2001..The aberrant transcript presumably arose as a result of a lack of splicing, and chemotherapy might modify the disease course by selecting the subpopulation of the CML clone expressing typical BCR-ABL mRNA dominantly...
Extracellular matrix regulates induction of alkaline phosphatase expression by ascorbic acid in human fibroblastsT Abe
Section of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka, Japan
J Cell Physiol 189:144-51. 2001....
[Protein S deficiency in three patients with thrombosis]R Minami
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
Rinsho Ketsueki 42:610-5. 2001..The third patient had a mutation in the site that is involved in binding to C4b-binding protein, which modifies the immune response. These three cases provide key insights into the pathophysiology of PS deficiency...
A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome: immunological analysis of B cells, T cells and cytokinesY Tamimoto
Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
Rheumatology (Oxford) 47:821-7. 2008..We performed a dose-escalation study for treatment of Japanese patients with autoimmune diseases including eight with SLE and one with Evans' syndrome...
Experiences of high-dose mizoribine as antimetabolite immunosuppressants for kidney transplantationN Nakamura
Department of Urology, Fukuoka University Hospital, Fukuoka, Japan
Transplant Proc 44:150-3. 2012..MZ controlled with blood concentrations showed less side effects, suggesting that high MZ doses could be safely used for an induction and maintenance antimetabolite...
Reduced-intensity stem-cell transplantation for adult acute lymphoblastic leukemia: a retrospective study of 33 patientsT Hamaki
Department of Transfusion Medicine, Metropolitan Fuchu Hospital, Tokyo, Japan
Bone Marrow Transplant 35:549-56. 2005..9 and 30.4%, respectively. These findings suggest the presence of a graft-versus-leukemia effect for ALL. RIST for ALL is worth considering for further evaluation...
Urinary leukotriene E4 in Henoch-Schonlein purpuraY Tsuji
Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan
Clin Exp Allergy 34:1259-61. 2004..Urinary leukotriene E4 (LTE4u) levels are a useful index of whole-body cysteinyl LT production in vivo. In this study, LTE4u was examined in children with HSP...
Optimization of anti-tumor necrosis factor-alpha single chain Fv displayed on phages for creation of functional antibodiesY Mukai
Laboratory of Pharmaceutical Proteomics, National Institute of Biomedical Innovation, Ibaraki, Japan
Pharmazie 61:889-90. 2006....
Neopterin is associated with plaque inflammation and destabilisation in human coronary atherosclerotic lesionsT Adachi
Department of Cardiology, Osaka City General Hospital, 2 13 22, Miyakojima hondori, Miyakojima ku, Osaka 534 0021, Japan
Heart 93:1537-41. 2007..Neopterin, a by-product of the guanosine triphosphate pathway, is produced by activated macrophages and serves as an activation marker for monocytes/macrophages...
Protective effects of anti-neutrophil antibody against myocardial ischemia/reperfusion injury in ratsT Kohtani
Department of Surgery II, Ehime University School of Medicine, Shitsukawa, Shigenobu, Onsen gun, Ehime, Japan
Eur Surg Res 34:313-20. 2002..In conclusion, Urge-8 is effective against myocardial I/R injury by suppressing certain functions and myocardial infiltration of neutrophils in rats...
Genetic variants of IL-13 signalling and human asthma and atopyA Heinzmann
University Children s Hospital, University of Freiburg, Freiburg, Germany
Hum Mol Genet 9:549-59. 2000..38 in males, 1.10 in females) rather than asthma. Thus, certain variants of IL-13 signalling are likely to be important promoters of human asthma; detailed functional analysis of their actions is needed...
Cloning and expression of a novel MAPKK-like protein kinase, lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cellsY Abe
First Department of Pathology, Ehime University School of Medicine, Shigenobu, Ehime 791 0295, Japan
J Biol Chem 275:21525-31. 2000..These data suggest that TOPK is a newly identified member of a novel MEK3/6-related MAPKK that may be enrolled in the activation of lymphoid cells and support testicular functions...
Microsatellite instability of each tumor in sporadic synchronous multiple colorectal cancersY Abe
Department of Functional Physiology, Nihon University School of Medicine, Nerima-ku, Tokyo 179-0072, Japan
Oncol Rep 8:299-304. 2001....
Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive mannerT Niikura
Department of Pharmacology and Neurosciences, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
J Neurosci 21:1902-10. 2001..The antagonizing function of the IGF-I/IGF-IR system against V642I-APP, which is further antagonized by IGFBP-3, provides a molecular clue to the understanding of AD pathophysiology and to the establishment of potential therapy for AD...
Modulation of multidrug resistance in a cancer cell line by anti-multidrug resistance-associated protein (MRP) ribozymeH Hatanaka
Department of Pathology, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259-1193, Japan
Anticancer Res 21:879-85. 2001..The hammerhead ribozyme-mediated simple suppression of MRP mRNA expression was not sufficient to reverse multidrug resistance in the cancer cell line KB8-5...
Fas/FasL mediated apoptosis of thyrocytes in Graves' diseaseN Sera
First Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan
Clin Exp Immunol 124:197-207. 2001..These interactions were also blocked by anti-FasL mAb. Our results suggest that the apoptotic cell death of both thyrocytes and infiltrating MNCs found in Graves' thyroid glands is regulated by IL-1beta through Fas/FasL interactions...
Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testesY Abe
First Department of Pathology and Hygiene, Ehime University School of Medicine, Shigenobu, Ehime 791 0295, Japan
J Biol Chem 276:44003-11. 2001..PRPK was shown to bind to p53 and to phosphorylate p53 at Ser-15. These results indicate that PRPK may play an important role in the cell cycle and cell apoptosis through phosphorylation of p53...
Feasibility of iodine-125 labeled anti-human hemoglobin antibody in the detection of bleeding sites from the large bowel-A preliminary studyG L Prado
Department of Radiology, Hirosaki University School of Medicine, Japan
Tohoku J Exp Med 194:141-6. 2001..Autoradiographs exquisitely demonstrated accumulation of isotope in the corresponding intestinal bleeding areas. These findings suggest that this method can be useful for scintigraphic localization of bleeding sites in the large bowel...
75- but not 55-kDa tumor necrosis factor receptor is active in the homotypic aggregation and proliferation of human lymphokine-activated T killer (T-LAK) cells in vitroY Abe
Second Department of Surgery, Ehime University School of Medicine, Japan
J Leukoc Biol 57:462-8. 1995..These findings indicated that 75- but not 55-kDa TNF-R is biologically active in the modulation of aggregation and proliferation of human T-LAK cells in vitro...
