Y Kobayashi

Summary

Affiliation: Kyowa Hakko Kogyo Co
Country: Japan

Publications

  1. ncbi request reprint The bronchoconstrictive action of evodiamine, an indoloquinazoline alkaloid isolated from the fruits of Evodia rutaecarpa, on guinea-pig isolated bronchus: possible involvement on vanilloid receptors
    Y Kobayashi
    Kyowa Hakko Kogyo Co, Ltd Tsukuba Research Laboratories, Ibaraki, Japan
    Planta Med 66:526-30. 2000
  2. ncbi request reprint The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors
    Y Kobayashi
    Kyowa Hakko Kogyo Co, Ltd, Tsukuba Research Laboratories, Ibaraki, Japan
    Planta Med 67:244-8. 2001
  3. ncbi request reprint Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist
    Y Kobayashi
    Kyowa Hakko Kogyo Co, Ltd, Tsukuba Research Laboratories, 2, Miyukigaoka, Tsukuba shi, Ibaraki 305 0841, Japan
    Planta Med 67:628-33. 2001
  4. ncbi request reprint Developmental toxicity of indium in cultured rat embryos
    M Nakajima
    Laboratory for Toxicological Research, Institute for Life Science Research, Asahi Chemical Industry Co, Ltd, Shizuoka, Japan
    Teratog Carcinog Mutagen 19:205-9. 1999
  5. ncbi request reprint Dietary intake of the flower extracts of German chamomile (Matricaria recutita L.) inhibited compound 48/80-induced itch-scratch responses in mice
    Y Kobayashi
    Kyowa Hakko Kogyo Co, Ltd Tsukuba Research Laboratories, Ibaraki, Japan
    Phytomedicine 10:657-64. 2003
  6. ncbi request reprint [Effect of liposome-encapsulated recombinant human superoxide dismutase (liposome-r-h-SOD) on the lung injury induced by Forssman antiserum in guinea pigs]
    K Nakagami
    Medicinal Research Laboratory, Toyo Jozo Co, Ltd, Shizuoka, Japan
    Nihon Yakurigaku Zasshi 97:41-9. 1991
  7. ncbi request reprint Comparative developmental toxicity study of indium in rats and mice
    M Nakajima
    Laboratory for Toxicological Research, Institute for Life Science Research, Asahi Chemical Industry Co, Ltd, Shizuoka, Japan
    Teratog Carcinog Mutagen 20:219-27. 2000
  8. ncbi request reprint Efficient production of saikosaponins in Bupleurum falcatum root fragments combined with signal transducers
    H Aoyagi
    Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan
    Appl Microbiol Biotechnol 57:482-8. 2001

Collaborators

Detail Information

Publications8

  1. ncbi request reprint The bronchoconstrictive action of evodiamine, an indoloquinazoline alkaloid isolated from the fruits of Evodia rutaecarpa, on guinea-pig isolated bronchus: possible involvement on vanilloid receptors
    Y Kobayashi
    Kyowa Hakko Kogyo Co, Ltd Tsukuba Research Laboratories, Ibaraki, Japan
    Planta Med 66:526-30. 2000
    ..Rutaecarpine, which belongs to the same indoloquinazoline-type alkaloid as evodiamine, showed neither bronchoconstrictive, desensitizing effects nor vanilloid antagonistic effects at all the concentrations examined (up to 200 microM)...
  2. ncbi request reprint The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors
    Y Kobayashi
    Kyowa Hakko Kogyo Co, Ltd, Tsukuba Research Laboratories, Ibaraki, Japan
    Planta Med 67:244-8. 2001
    ....
  3. ncbi request reprint Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist
    Y Kobayashi
    Kyowa Hakko Kogyo Co, Ltd, Tsukuba Research Laboratories, 2, Miyukigaoka, Tsukuba shi, Ibaraki 305 0841, Japan
    Planta Med 67:628-33. 2001
    ..Evodiamine would induce heat loss and heat production at the same time and dissipate food energy, preventing the accumulation of perivisceral fat and the body weight increase...
  4. ncbi request reprint Developmental toxicity of indium in cultured rat embryos
    M Nakajima
    Laboratory for Toxicological Research, Institute for Life Science Research, Asahi Chemical Industry Co, Ltd, Shizuoka, Japan
    Teratog Carcinog Mutagen 19:205-9. 1999
    ....
  5. ncbi request reprint Dietary intake of the flower extracts of German chamomile (Matricaria recutita L.) inhibited compound 48/80-induced itch-scratch responses in mice
    Y Kobayashi
    Kyowa Hakko Kogyo Co, Ltd Tsukuba Research Laboratories, Ibaraki, Japan
    Phytomedicine 10:657-64. 2003
    ..The inhibitory effects of the dietary intake of the German chamomile extracts on compound 48/80-induced itch-scratch response were comparable to oxatomide (10 mg/kg, p.o.), an anti-allergic agent...
  6. ncbi request reprint [Effect of liposome-encapsulated recombinant human superoxide dismutase (liposome-r-h-SOD) on the lung injury induced by Forssman antiserum in guinea pigs]
    K Nakagami
    Medicinal Research Laboratory, Toyo Jozo Co, Ltd, Shizuoka, Japan
    Nihon Yakurigaku Zasshi 97:41-9. 1991
    ..These findings suggest that superoxide radical may take part in the lung injury induced by Forssman antiserum. Liposome-r-h-SOD, which adheres to and/or is endocytosed by endothelial cells, may protect the lung from oxygen radicals...
  7. ncbi request reprint Comparative developmental toxicity study of indium in rats and mice
    M Nakajima
    Laboratory for Toxicological Research, Institute for Life Science Research, Asahi Chemical Industry Co, Ltd, Shizuoka, Japan
    Teratog Carcinog Mutagen 20:219-27. 2000
    ..Toxicokinetic factors may be involved in this different susceptibility. Teratogenesis Carcinog. Mutagen. 20:219-227, 2000...
  8. ncbi request reprint Efficient production of saikosaponins in Bupleurum falcatum root fragments combined with signal transducers
    H Aoyagi
    Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan
    Appl Microbiol Biotechnol 57:482-8. 2001
    ..A large amount of root fragments were prepared using a blender and cultivated (23 g-dry root/l) with 400 microM MeJA and 20 mM CaCl2, resulting in a high concentration of saikosaponins (747.3 mg/l)...