Research Topics
| Ayako KamimuraSummaryAffiliation: Kyowa Hakko Kogyo Co Country: Japan Publications
| Collaborators
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Detail Information
Publications
Investigation of topical application of procyanidin B-2 from apple to identify its potential use as a hair growing agentA Kamimura
Tsukuba Research Laboratories, Kyowa Hakko Kogyo Co, Ibaraki, Japan
Phytomedicine 7:529-36. 2000..99 +/- 2.58 (mean +/- SD)/0.25 cm2; placebo, -0.82 +/- 3.40 (mean +/- SD)/0.25 cm2; P < 0.02, two-sample t test). Procyanidin B-2 therapy shows potential as a safe and promising cure for male pattern baldness...
Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory studyA Kamimura
Tsukuba Research Laboratories, Kyowa Hakko Kogyo Co, 2, Miyukigaoka, Tsukuba, Ibaraki 305 0841, Japan
Br J Dermatol 146:41-51. 2002..We have previously reported that several selective protein kinase C (PKC) inhibitors, including procyanidin B-2, promote hair epithelial cell growth and stimulate anagen induction...
Procyanidin B-3, isolated from barley and identified as a hair-growth stimulant, has the potential to counteract inhibitory regulation by TGF-beta1Ayako Kamimura
Tsukuba Research Laboratories, Kyowa Hakko Kogyo Co, Tsukuba, Ibaraki, Japan
Exp Dermatol 11:532-41. 2002....
Procyanidin oligomers counteract TGF-beta1- and TGF-beta2-induced apoptosis in hair epithelial cells: an insight into their mechanismsA Kamimura
Tsukuba Research Laboratories, Kyowa Hakko Kogyo Co, Tsukuba, Ibaraki, Japan
Skin Pharmacol Physiol 19:259-65. 2006....
Phosphatidic acid has a potential to promote hair growth in vitro and in vivo, and activates mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in hair epithelial cellsTomoya Takahashi
Tsukuba Research Laboratories, Kyowa Hakko Kogyo Company, 2 Miyukigaoka, Tsukuba, Ibaraki 305 0841, Japan
J Invest Dermatol 121:448-56. 2003....
Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritusErika Hashizume
Healthcare Products Development Center, Kyowa Hakko Bio, Tsukuba, Ibaraki, Japan
Clin Cosmet Investig Dermatol 6:43-9. 2013..Its other biological and physiological effects on the skin have not been elucidated. We investigated the effects of AHYP on the skin-barrier function, focusing on ceramide synthesis and the effects of topical AHYP on atopic dermatitis...
Increasing effect of an oral intake of L-hydroxyproline on the soluble collagen content of skin and collagen fragments in rat serumMami Aoki
Healthcare Products Development Center, Kyowa Hakko Bio Co, Ltd, Ibaraki, Japan
Biosci Biotechnol Biochem 76:1242-4. 2012..This result suggests that oral Hyp augmented collagen metabolism...
