S Yonemura

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. pmc Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins
    S Yonemura
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Cell Biol 145:1497-509. 1999
  2. pmc Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2
    S Yonemura
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606 01, Japan
    J Cell Biol 140:885-95. 1998
  3. pmc Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway
    M Hirao
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Japan
    J Cell Biol 135:37-51. 1996
  4. pmc ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosis
    T Kondo
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Cell Biol 139:749-58. 1997
  5. pmc Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
    T Matsui
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Cell Biol 140:647-57. 1998
  6. ncbi request reprint Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins
    S Tsukita
    College of Medical Technology, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Biol Chem 274:34507-10. 1999
  7. ncbi request reprint Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout
    Y Doi
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Biol Chem 274:2315-21. 1999
  8. ncbi request reprint ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transduction
    S Tsukita
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Yoshida Konoe, Sakyo ku, Kyoto 606, Japan
    Curr Opin Cell Biol 9:70-5. 1997
  9. ncbi request reprint ERM proteins: head-to-tail regulation of actin-plasma membrane interaction
    S Tsukita
    College of Medical Technology, Kyoto University, Japan
    Trends Biochem Sci 22:53-8. 1997
  10. pmc Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues
    Y Ando-Akatsuka
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Japan
    J Cell Biol 133:43-7. 1996

Collaborators

Detail Information

Publications16

  1. pmc Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins
    S Yonemura
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Cell Biol 145:1497-509. 1999
    ..Furthermore, immunodetection with a phosphorylated ERM-specific antibody and site-directed mutagenesis suggested that ERM proteins phosphorylated at their COOH-terminal threonine residue represent activated ERM proteins...
  2. pmc Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2
    S Yonemura
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606 01, Japan
    J Cell Biol 140:885-95. 1998
    ..From these findings, we conclude that ERM proteins bind to integral membrane proteins bearing a positively charged amino acid cluster in their juxta-membrane cytoplasmic domain...
  3. pmc Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway
    M Hirao
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Japan
    J Cell Biol 135:37-51. 1996
    ..These findings indicate that Rho regulates the CD44/ERM complex formation in vivo and that the phosphatidylinositol turnover may be involved in this regulation mechanism...
  4. pmc ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosis
    T Kondo
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Cell Biol 139:749-58. 1997
    ..The physiological relevance of this ERM protein-based microvillar breakdown in apoptosis will be discussed...
  5. pmc Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
    T Matsui
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Cell Biol 140:647-57. 1998
    ....
  6. ncbi request reprint Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins
    S Tsukita
    College of Medical Technology, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Biol Chem 274:34507-10. 1999
  7. ncbi request reprint Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout
    Y Doi
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Biol Chem 274:2315-21. 1999
    ..These findings favor the notion that ERM proteins are functionally redundant at the cellular as well as the whole body level...
  8. ncbi request reprint ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transduction
    S Tsukita
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Yoshida Konoe, Sakyo ku, Kyoto 606, Japan
    Curr Opin Cell Biol 9:70-5. 1997
    ..Furthermore, identification of the neurofibromatosis type 2 tumour suppressor, which shows striking sequence similarity to ERM proteins, has increased interest in this family...
  9. ncbi request reprint ERM proteins: head-to-tail regulation of actin-plasma membrane interaction
    S Tsukita
    College of Medical Technology, Kyoto University, Japan
    Trends Biochem Sci 22:53-8. 1997
    ..Specific signals activate ERM proteins to bind actin filaments and the plasma membrane; these include phosphoinositides and/or phosphorylation mechanisms, which might be located downstream from the Rho-dependent pathway...
  10. pmc Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues
    Y Ando-Akatsuka
    Department of Cell Biology, Faculty of Medicine, Kyoto University, Japan
    J Cell Biol 133:43-7. 1996
    ..Implications of these data and novel experimental options in cell biological research are discussed...
  11. ncbi request reprint A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites
    N Sato
    Department of Information Physiology, National Institute for Physiological Sciences, Aichi, Japan
    J Cell Sci 103:131-43. 1992
    ..We conclude that at least one of the members of the ezrin-radixin-moesin family is concentrated at specific regions where actin filaments are densely associated with plasma membranes...
  12. pmc The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy
    M Itoh
    Department of Information Physiology, National Institute for Physiological Sciences, Aichi, Japan
    J Cell Biol 121:491-502. 1993
    ..Possible functions of the 220-kD protein (ZO-1) are discussed with special reference to the molecular mechanism for adherens and tight junction formation...
  13. pmc Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions
    M Furuse
    Department of Information Physiology, National Institute for Physiological Sciences, Okazaki, Aichi, Japan
    J Cell Biol 127:1617-26. 1994
    ..The coincidence of the sequence necessary for the ZO-1 association with that for the TJ localization suggests that the association with underlying cytoskeletons through ZO-1 is required for occludin to be localized at TJ...
  14. pmc Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle
    N Tokai
    The Institute of Medical Science, The University of Tokyo, Japan
    EMBO J 15:457-67. 1996
    ..Thus, we propose that Kid might play a role(s) in regulating the chromosomal movement along microtubules during mitosis...
  15. pmc Occludin: a novel integral membrane protein localizing at tight junctions
    M Furuse
    Department of Information Physiology, National Institute for Physiological Sciences, Aichi, Japan
    J Cell Biol 123:1777-88. 1993
    ..These findings revealed that an integral membrane protein localizing at tight junctions is now identified, which we designated as "occludin."..
  16. ncbi request reprint Rho-dependent transfer of Citron-kinase to the cleavage furrow of dividing cells
    M Eda
    Department of Pharmacology, Kyoto University Faculty of Medicine, Sakyo, Kyoto 606-8501, Japan
    J Cell Sci 114:3273-84. 2001
    ..Rho is then activated, binds to Citron-K and translocates it to cell cortex, where the complex is then concentrated in the cleavage furrow by the action of actin cytoskeleton beneath the equator of dividing cells...