Research Topics
Genomes and Genes | Shin ichi YanagawaSummaryAffiliation: Kyoto University Country: Japan Publications
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Publications
Biochemical characterization of the Drosophila axin proteinS Yanagawa
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, 606 8507, Kyoto, Japan
FEBS Lett 474:189-94. 2000..Moreover, interactions between Daxin and Zeste-white 3, Armadillo, Dishevelled, protein phosphatase 2A and Daxin itself were shown, providing direct evidence that Daxin is a scaffold protein in the Wingless pathway...
Identification of Notch1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virusS Yanagawa
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
J Virol 74:9786-91. 2000..Thus, Notch1 is a major target of provirus insertional mutagenesis in these T-cell lymphomas...
Casein kinase I phosphorylates the Armadillo protein and induces its degradation in DrosophilaShin ichi Yanagawa
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
EMBO J 21:1733-42. 2002..His-tagged Arm was phosphorylated by CKIalpha in vitro on a set of serine and threonine residues that are also phosphorylated by Zeste-white 3. Thus, we propose that CKI phosphorylates Arm and stimulates its degradation...
Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interferenceHiroko Matsubayashi
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, Kyoto 606 85071, Japan
Mol Cell Biol 24:2012-24. 2004....
GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathwayNorio Tezuka
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
Biochem Biophys Res Commun 356:648-54. 2007..The finding that GRB10 interferes with the binding of Axin to LRP6 indicated a possible molecular mechanism by which the overexpression of GRB10 suppresses Wnt signaling...
