Nobuyuki Yamasaki

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. pmc Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders
    Nobuyuki Yamasaki
    Frontier Technology Center, Kyoto University Graduate School of Medicine, Japan
    Mol Brain 1:6. 2008
  2. pmc Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice
    Keizo Takao
    Genetic Engineering and Functional Genomics Group, Frontier Technology Center, Kyoto University Graduate School of Medicine, Kyoto, Japan
    PLoS ONE 5:e9460. 2010
  3. ncbi request reprint [Stress and animal model of psychiatric disease]
    Tsuyoshi Miyakawa
    Nihon Yakurigaku Zasshi 126:189-93. 2005
  4. ncbi request reprint Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity
    Masafumi Ihara
    Biochemistry and Cell Biology Unit, HMRO, Kyoto University Graduate School of Medicine, Yoshida Konoe, Sakyo, Kyoto 606 8501, Japan
    Neuron 53:519-33. 2007
  5. ncbi request reprint A mouse model characterizing features of vascular dementia with hippocampal atrophy
    Keiko Nishio
    Department of Neurology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8507 Japan
    Stroke 41:1278-84. 2010
  6. pmc Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice
    Koichi Tanda
    Genetic Engineering and Functional Genomics Group, Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Mol Brain 2:19. 2009
  7. doi request reprint α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion
    Hodaka Yamakado
    Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Neurosci Res 73:173-7. 2012

Detail Information

Publications7

  1. pmc Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders
    Nobuyuki Yamasaki
    Frontier Technology Center, Kyoto University Graduate School of Medicine, Japan
    Mol Brain 1:6. 2008
    ..Based on these results, we propose that an "immature DG" in adulthood might induce alterations in behavior and serve as a promising candidate endophenotype of schizophrenia and other human psychiatric disorders...
  2. pmc Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice
    Keizo Takao
    Genetic Engineering and Functional Genomics Group, Frontier Technology Center, Kyoto University Graduate School of Medicine, Kyoto, Japan
    PLoS ONE 5:e9460. 2010
    ..These findings indicate that CaMKIV might not be essential for fear memory or spatial memory, although it is possible that the activities of other neural mechanisms or signaling pathways compensate for the CaMKIV deficiency...
  3. ncbi request reprint [Stress and animal model of psychiatric disease]
    Tsuyoshi Miyakawa
    Nihon Yakurigaku Zasshi 126:189-93. 2005
  4. ncbi request reprint Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity
    Masafumi Ihara
    Biochemistry and Cell Biology Unit, HMRO, Kyoto University Graduate School of Medicine, Yoshida Konoe, Sakyo, Kyoto 606 8501, Japan
    Neuron 53:519-33. 2007
    ..Taken together, these data show that Sept4 may be involved in PD as a dual susceptibility factor, as its insufficiency can diminish dopaminergic neurotransmission and enhance alpha-synuclein neurotoxicity...
  5. ncbi request reprint A mouse model characterizing features of vascular dementia with hippocampal atrophy
    Keiko Nishio
    Department of Neurology, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8507 Japan
    Stroke 41:1278-84. 2010
    ..However, as subcortical ischemic vascular dementia progresses over time, the longer-term effects that characterize the mouse model are not known...
  6. pmc Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice
    Koichi Tanda
    Genetic Engineering and Functional Genomics Group, Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Mol Brain 2:19. 2009
    ..We also examined the role of nNOS in dopamine/DARPP-32 signaling in striatal slices from nNOS KO mice and the effects of the administration of a dopamine D1 receptor agonist on behavior in nNOS KO mice...
  7. doi request reprint α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion
    Hodaka Yamakado
    Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Neurosci Res 73:173-7. 2012
    ..Our α-syn BAC tg mice could be a valuable tool to evaluate α-syn gene dosage effects in vivo...