K Yamamoto

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. ncbi request reprint GPR1 regulates filamentous growth through FLO11 in yeast Saccharomyces cerevisiae
    H Tamaki
    Graduate School of Biostudies, Kyoto University, Kyoto, 606 8502, Japan
    Biochem Biophys Res Commun 267:164-8. 2000
  2. ncbi request reprint Glucose-dependent cell size is regulated by a G protein-coupled receptor system in yeast Saccharomyces cerevisiae
    Hisanori Tamaki
    Division of Integrated Life Sciences, Graduate School of Biostudies, Kyoto University, Kyoto 606 8502, Japan
    Genes Cells 10:193-206. 2005
  3. pmc Expression of two glutathione S-transferase genes in the yeast Issatchenkia orientalis is induced by o-dinitrobenzene during cell growth arrest
    H Tamaki
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto 606 8502, Japan
    J Bacteriol 181:2958-62. 1999
  4. ncbi request reprint G-protein coupled receptor from yeast Saccharomyces cerevisiae
    C W Yun
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan
    Biochem Biophys Res Commun 240:287-92. 1997
  5. ncbi request reprint Gpr1p, a putative G-protein coupled receptor, regulates glucose-dependent cellular cAMP level in yeast Saccharomyces cerevisiae
    C W Yun
    Graduate School of Agriculture, Kyoto University, Kyoto, 606 8502, Japan
    Biochem Biophys Res Commun 252:29-33. 1998
  6. ncbi request reprint Characterization of endo-alpha-N-acetylgalactosaminidase from Bacillus sp. and syntheses of neo-oligosaccharides using its transglycosylation activity
    H Ashida
    Graduate School of Agriculture, Kyoto University, Kyoto, 606 8502, Japan
    Arch Biochem Biophys 373:394-400. 2000
  7. ncbi request reprint Cloning of a gene encoding thermostable cellobiohydrolase from Thermoascus aurantiacus and its expression in yeast
    J Hong
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo ku, 606 8502 Kyoto, Japan
    Appl Microbiol Biotechnol 63:42-50. 2003
  8. ncbi request reprint Modification of allergic inflammation in murine model of rhinitis by different bacterial ligands: involvement of mast cells and dendritic cells
    K Yamamoto
    Department of Microbiology, Head and Neck Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Clin Exp Allergy 36:760-9. 2006
  9. ncbi request reprint Trypsin inhibitory activity of bovine fetuin de-O-glycosylated by endo-alpha-N-acetylgalactosaminidase
    H Ashida
    Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Japan
    Biosci Biotechnol Biochem 64:2266-8. 2000
  10. ncbi request reprint Transcriptional regulation of tyrosine phenol-lyase gene of Erwinia herbicola AJ2985
    H Suzuki
    Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan
    Biosci Biotechnol Biochem 59:2339-41. 1995

Collaborators

Detail Information

Publications88

  1. ncbi request reprint GPR1 regulates filamentous growth through FLO11 in yeast Saccharomyces cerevisiae
    H Tamaki
    Graduate School of Biostudies, Kyoto University, Kyoto, 606 8502, Japan
    Biochem Biophys Res Commun 267:164-8. 2000
    ..These results indicate that GPR1 regulates both pseudohyphal and invasive growth by a cAMP-dependent mechanism...
  2. ncbi request reprint Glucose-dependent cell size is regulated by a G protein-coupled receptor system in yeast Saccharomyces cerevisiae
    Hisanori Tamaki
    Division of Integrated Life Sciences, Graduate School of Biostudies, Kyoto University, Kyoto 606 8502, Japan
    Genes Cells 10:193-206. 2005
    ..Our study indicates that the yeast G-protein coupled receptor system consisting of Gpr1 and Gpa2 regulates cell size by affecting both growth rate and cell division...
  3. pmc Expression of two glutathione S-transferase genes in the yeast Issatchenkia orientalis is induced by o-dinitrobenzene during cell growth arrest
    H Tamaki
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto 606 8502, Japan
    J Bacteriol 181:2958-62. 1999
    ..orientalis cells sense xenobiotics and arrest cell growth as a mechanism for preventing the induction of mutations by these compounds, while the levels of expression of the GST genes are up-regulated for detoxification...
  4. ncbi request reprint G-protein coupled receptor from yeast Saccharomyces cerevisiae
    C W Yun
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan
    Biochem Biophys Res Commun 240:287-92. 1997
    ..It is likely that a Gpr1p monitors the extracellular signal such as nutrition and transduce it via Gpa2p a possible positive regulator of cAMP level...
  5. ncbi request reprint Gpr1p, a putative G-protein coupled receptor, regulates glucose-dependent cellular cAMP level in yeast Saccharomyces cerevisiae
    C W Yun
    Graduate School of Agriculture, Kyoto University, Kyoto, 606 8502, Japan
    Biochem Biophys Res Commun 252:29-33. 1998
    ..Our findings suggest that Gpr1p is part of the nutrition sensing machinery most likely acting as a receptor to monitor glucose as well as other fermentable sugars and regulate cellular cAMP levels...
  6. ncbi request reprint Characterization of endo-alpha-N-acetylgalactosaminidase from Bacillus sp. and syntheses of neo-oligosaccharides using its transglycosylation activity
    H Ashida
    Graduate School of Agriculture, Kyoto University, Kyoto, 606 8502, Japan
    Arch Biochem Biophys 373:394-400. 2000
    ..Using this transglycosylation activity of the endoglycosidase, it may be possible to synthesize neo-oligosaccharides...
  7. ncbi request reprint Cloning of a gene encoding thermostable cellobiohydrolase from Thermoascus aurantiacus and its expression in yeast
    J Hong
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo ku, 606 8502 Kyoto, Japan
    Appl Microbiol Biotechnol 63:42-50. 2003
    ..0. The recombinant enzyme was found to be highly glycosylated and this glycosylation was shown to contribute to the thermostability of the enzyme. CBHI expression was shown to be induced at higher temperature in T. aurantiacus...
  8. ncbi request reprint Modification of allergic inflammation in murine model of rhinitis by different bacterial ligands: involvement of mast cells and dendritic cells
    K Yamamoto
    Department of Microbiology, Head and Neck Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Clin Exp Allergy 36:760-9. 2006
    ..It has been suggested that airway bacterial infections exacerbate allergic disorders, and bacterial components in the air affect allergic inflammation via Toll-like receptors expressed on mast cells and dendritic cells in the airway mucosa...
  9. ncbi request reprint Trypsin inhibitory activity of bovine fetuin de-O-glycosylated by endo-alpha-N-acetylgalactosaminidase
    H Ashida
    Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Japan
    Biosci Biotechnol Biochem 64:2266-8. 2000
    ..In contrast, the trypsin inhibitory activity of asialo- and de-O-glycosylated fetuin decreased about a half and one-third of that of native fetuin, respectively...
  10. ncbi request reprint Transcriptional regulation of tyrosine phenol-lyase gene of Erwinia herbicola AJ2985
    H Suzuki
    Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan
    Biosci Biotechnol Biochem 59:2339-41. 1995
    ..The 5' flanking region of its gene, tpl, was analyzed and its transcriptional start point was determined. A presumed -35, -10 promoter region, TyrR box, and operator-like region were also found in this region...
  11. ncbi request reprint Mechanism of site-specific DNA damage induced by methylhydrazines in the presence of copper(II) or manganese(III)
    S Kawanishi
    Department of Public Health, Faculty of Medicine, Kyoto University, Japan
    Biochemistry 30:3069-75. 1991
    ..These results suggest that the Cu(I)-peroxide complex rather than the .CH3 plays a more important role in methylhydrazine plus Cu(II)-induced DNA damage...
  12. ncbi request reprint Analysis of low temperature inducible mechanism of gamma-glutamyltranspeptidase of Escherichia coli K-12
    W Hashimoto
    Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan
    Biosci Biotechnol Biochem 61:34-9. 1997
    ....
  13. ncbi request reprint Microbial system for polysaccharide depolymerization: enzymatic route for gellan depolymerization by Bacillus sp. GL1
    W Hashimoto
    Research Institute for Food Science, Kyoto University, Uji, Japan
    Arch Biochem Biophys 339:17-23. 1997
    ....
  14. ncbi request reprint Binding specificity of Lactobacillus to glycolipids
    K Yamamoto
    Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan
    Biochem Biophys Res Commun 228:148-52. 1996
    ..This indicated that sialic acid inhibited the adhesion of L.casei to tissues. L.casei actually bound nonacid glycosphingolipids but not acid glycosphingolipids extracted from the small intestinal mucosa of rats...
  15. ncbi request reprint Transcriptional regulation of tyrosine phenol-lyase gene mediated through TyrR and cAMP receptor protein
    T Katayama
    Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Sakyo ku, Japan
    Biosci Biotechnol Biochem 63:1823-7. 1999
    ..The DNA bending between two TyrR boxes, which is triggered by the binding of cAMP receptor protein, may facilitate the conformational change of TyrRs...
  16. ncbi request reprint Enhancement of activity-dependent calcium increase by neurotrophin-4 in visual cortex pyramidal neurons
    N Kato
    Department of Integrative Brain Science, Kyoto University Graduate School of Medicine, Kyoto 606 8501, Japan
    Brain Res 832:179-83. 1999
    ..With ryanodine injected intracellularly, the effect of NT-4 was significantly reduced, suggesting an involvement of intracellular calcium release in this NT-4-induced enhancement of calcium transient...
  17. ncbi request reprint Effects of A-P translation and rotation on the wear of UHMWPE in a total knee joint simulator
    K Kawanabe
    Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Japan
    J Biomed Mater Res 54:400-6. 2001
    ..The shapes of the tibial wear tracks were rectangular and the area of the track increased when rotation and translation were added...
  18. ncbi request reprint Effects of amphetamine on rat embryos developing in vitro
    Y Yamamoto
    Department of Legal Medicine, Kyoto University Faculty of Medicine, Japan
    Reprod Toxicol 12:133-7. 1998
    ..The observed embryotoxic effects appeared to depend on the AMP concentration. Our results demonstrated the direct embryotoxic effects of AMP on rats. The direct dysmorphogenic effect of AMP might be weaker than that of methamphetamine...
  19. pmc Distinct temporal profiles of activity-dependent calcium increase in pyramidal neurons of the rat visual cortex
    N Kato
    Department of Integrative Brain Science, Kyoto University Graduate School of Medicine, Kyoto 606 8501 and Japan Science and Technology Corporation, Saitama 332 0012, Japan
    J Physiol 519:467-79. 1999
    ..6. Such variety in the mechanisms of calcium increase may be relevant to the role of calcium as a versatile second messenger for various types of synaptic plasticity...
  20. ncbi request reprint Specificity of mutations induced by riboflavin mediated photosensitization in the supF gene of Escherichia coli
    K Tano
    Research Reactor Institute, Kyoto University, Kumatori, Osaka 590 0494
    Mutat Res 420:7-13. 1998
    ..Riboflavin-mediated photosensitization may also produce lesions on DNA causing G:C to C:G changes by unknown mechanisms...
  21. ncbi request reprint Uterine expression of prostaglandin H2 synthase in late pregnancy and during parturition in prostaglandin F receptor-deficient mice
    K Tsuboi
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Kyoto University, Japan
    Endocrinology 141:315-24. 2000
    ..These results suggest that COX-1-derived PGs are responsible for the induction of luteolysis, and that COX-2-derived PGs play a role in the final pathway of parturition...
  22. ncbi request reprint Oxidation of specific SH protein of mitochondria by photodynamic action of hematoporphyrin. Relevance to uncoupling of oxidative phosphorylation
    K Yamamoto
    Department of Public Health, Faculty of Medicine, Kyoto University, Japan
    Biochem Pharmacol 42:1087-92. 1991
    ..The possibility of the uncoupling of oxidative phosphorylation through such a modification of the Pi/H+ symporter is discussed...
  23. ncbi request reprint Chemoenzymatic synthesis of a novel glycopeptide using a microbial endoglycosidase
    K Yamamoto
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan
    Carbohydr Res 305:415-22. 1997
    ..The glycosylated Peptide T was highly stable against proteolysis in comparison to native Peptide T and N-acetylglucosaminyl Peptide T...
  24. pmc Listeriolysin O derived from Listeria monocytogenes inhibits the effector phase of an experimental allergic rhinitis induced by ovalbumin in mice
    K Yamamoto
    Department of Microbiology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Clin Exp Immunol 144:475-84. 2006
    ..Taken together, these data showed that rLLO suppresses the effector phase of allergic rhinitis by inhibition of Th2 cell recruitment to nasal mucosa and type I allergic reaction...
  25. pmc Interleukin-12 gene expression in human monocyte-derived macrophages stimulated with Mycobacterium bovis BCG: cytokine regulation and effect of NK cells
    H Matsumoto
    Department of Infection and Inflammation, Chest Disease Research Institute, Kyoto University, Japan
    Infect Immun 65:4405-10. 1997
    ..We concluded that the coexistence of NK cells was essential for the induction of IL-12 in MDM stimulated with BCG rather than through the secretion of IFN-gamma...
  26. ncbi request reprint Peripheral blood T-cell responses to pyruvate dehydrogenase complex in primary biliary cirrhosis: role of antigen-presenting dendritic cells
    S M Akbar
    Ehime University School of Medicine, Ehime, Japan, Teikyo University Mizonokuchi Hospital, Kanagawa, Japan
    Eur J Clin Invest 31:639-46. 2001
    ..This is the first report on the effectiveness of antigen-pulsed DCs for the elucidation of autoantigen-specific immune response in human autoimmune diseases...
  27. ncbi request reprint Similarity among the Drosophila (6-4)photolyase, a human photolyase homolog, and the DNA photolyase-blue-light photoreceptor family
    T Todo
    Radiation Biology Center, Kyoto University, Kyoto, Japan
    Science 272:109-12. 1996
    ..A homolog of the Drosophila (6-4)photolyase gene was also cloned from human cells...
  28. ncbi request reprint Enzymatic syntheses of T antigen-containing glycolipid mimicry using the transglycosylation activity of endo-alpha-N-acetylgalactosaminidase
    H Ashida
    Laboratory of Molecular Biology of Bioresponse, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Japan
    Carbohydr Res 330:487-93. 2001
    ....
  29. ncbi request reprint Purification, molecular cloning, and expression of lipase from Pseudomonas aeruginosa
    M Chihara-Siomi
    Institute for Chemical Research, Kyoto University, Japan
    Arch Biochem Biophys 296:505-13. 1992
    ..Expression plasmids encoding lipA followed by the complete or incomplete lipB gene downstream of the lac promoter of pUC18 were constructed. lipA was expressed in Escherichia coli 1100 only in the presence of the complete lipB gene...
  30. ncbi request reprint Site-specific DNA damage and 8-hydroxydeoxyguanosine formation by hydroxylamine and 4-hydroxyaminoquinoline 1-oxide in the presence of Cu(II): role of active oxygen species
    K Yamamoto
    Department of Public Health, Faculty of Medicine, Kyoto University, Japan
    Carcinogenesis 14:1397-401. 1993
    ..The role of Cu(II)-mediated DNA damage and 8-OH-dG formation in the genotoxicity of NH2OH, 4-HAQO and 4-NQO is discussed...
  31. ncbi request reprint Morphological imaging in the localization of neuroendocrine gastroenteropancreatic tumors found by somatostatin receptor scintigraphy
    T Saga
    Department of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto, 606 8507, Japan
    Acta Radiol 46:227-32. 2005
    ..To evaluate the necessity of morphological images (MI) in reading somatostatin receptor scintigraphy (SRS) in patients with suspected neuroendocrine gastroenteropancreatic (GEP) tumors...
  32. ncbi request reprint Binding of CO at the Pro2 side is crucial for the activation of CO-sensing transcriptional activator CooA. (1)H NMR spectroscopic studies
    K Yamamoto
    Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Kyoto 606-8501, Japan
    J Biol Chem 276:11473-6. 2001
    ..These observations are consistent with the view that the movement of the NH(2) terminus triggers the conformational transition to the DNA binding form...
  33. ncbi request reprint Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice
    S Kawasaki
    Department of Respiratory Medicine, School of Medicine, University of Tokyo, Tokyo, Japan
    J Immunol 166:2055-62. 2001
    ..This study also represents the first success in controlling Th2 cytokine production in vivo by targeting a chemokine...
  34. pmc Listeriolysin O, a cytolysin derived from Listeria monocytogenes, inhibits generation of ovalbumin-specific Th2 immune response by skewing maturation of antigen-specific T cells into Th1 cells
    K Yamamoto
    Department of Microbiology, Kyoto University Graduate School of Medicine, Japan
    Clin Exp Immunol 142:268-74. 2005
    ..Taken together, these data show clearly that LLO is capable of inhibiting Th2 immune response by skewing differentiation of antigen-specific T cells into Th1 cells...
  35. ncbi request reprint Non-point pollution of Ishikari river, Hokkaido, Japan
    H Tachibana
    Graduate School of Engineering, Hokkaido University, Sapporo, Japan
    Water Sci Technol 44:1-8. 2001
    ....
  36. ncbi request reprint Development of dento-maxillofacial cone beam X-ray computed tomography system
    K Yamamoto
    Hitachi Medico Technology Co, Ltd, Chiba, Japan
    Orthod Craniofac Res 6:160-2. 2003
    ..The developed system has sufficient spatial resolution, resolution of 3-D images and image distortion for diagnosis of dentomaxillofacial region...
  37. pmc The effects of CD40- and interleukin (IL-4)-activated CD23+ cells on the production of IL-10 by mononuclear cells in Graves' disease: the role of CD8+ cells
    K Uchimura
    Department of Internal Medicine, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan
    Clin Exp Immunol 128:308-12. 2002
    ....
  38. ncbi request reprint Telomerase inhibition enhances apoptosis in human acute leukemia cells: possibility of antitelomerase therapy
    A Nakajima
    First Department of Internal Medicine, Tokyo Medical University, Shinjuku ku, Japan
    Leukemia 17:560-7. 2003
    ..These results suggest that antitelomerase therapy may be useful in some acute leukemias in combination with antileukemic agents such as daunorubicin...
  39. pmc Peroxisome proliferator-activated receptor-gamma haploinsufficiency enhances B cell proliferative responses and exacerbates experimentally induced arthritis
    K Setoguchi
    Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    J Clin Invest 108:1667-75. 2001
    ..These findings indicate that PPAR gamma plays a critical role in the control of B cell response and imply a role in diseases in which B cell hyperreactivity is involved, such as arthritis and autoimmunity...
  40. ncbi request reprint Pancreatic islet regeneration by ephedrine in mice with streptozotocin-induced diabetes
    L M Xiu
    Third Department of Internal Medicine, Akita University School of Medicine. Japan
    Am J Chin Med 29:493-500. 2001
    ..It is therefore suggested that Ephedrae herba may regenerate atrophied pancreatic islets, restore the secretion of insulin, and thus correct hyperglycemia...
  41. ncbi request reprint Association of transporter associated with antigen processing genes with Beh├žet's disease in Japanese
    K Takizawa
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada cho, Shinjuku ku, Tokyo, Japan
    Autoimmunity 36:161-5. 2003
    ..5%) as compared to the control group (0.0%). [p = 0.03, RR = 15.4]. These results suggest the possibility that TAP molecule play some part in formation of skin lesion, such as erythema nodosum in BD in Japanese...
  42. ncbi request reprint Serum hepatocyte growth factor levels are increased in patients with congestive heart failure
    S Ueno
    Department of Cardiology, Jichi Medical School, Minamikawachi-machi, Tochigi, Japan
    J Card Fail 7:329-34. 2001
    ..CONCLUSIONS: HGF levels in serum are increased in patients with acute exacerbation of CHF...
  43. ncbi request reprint An immunohistological study of the localization characteristics of thymus and activation-regulated chemokine in the allergic inferior turbinate mucosa with reference to the effectiveness of trichloroacetic acid treatment
    K Yao
    Department of Otorhinolaryngology, Kitasato University School of Medicine, Kanagawa, Japan
    Am J Rhinol 15:395-402. 2001
    ....
  44. ncbi request reprint FcgammaRIIB gene polymorphisms in Japanese periodontitis patients
    K Yasuda
    Division of Periodontology, Department of Oral Biological Science, Niigata University, Graduate School of Medical and Dental Sciences, Gakkocho dori, Niigata, Japan
    Genes Immun 4:541-6. 2003
    ..011). These results document the association of FcgammaRIIB gene polymorphisms with susceptibility to periodontitis in the Japanese...
  45. ncbi request reprint Verification of the computational dosimetry system in JAERI (JCDS) for boron neutron capture therapy
    H Kumada
    Department of Research Reactor, Tokai Research Establishment, Japan Atomic Energy Research Institute, Tokai, Ibaraki, Japan
    Phys Med Biol 49:3353-65. 2004
    ..These basic and clinical verifications demonstrated that JCDS has enough performance for the BNCT dosimetry. Further investigations are recommended for precise dose distribution and faster calculation environment...
  46. doi request reprint Onecut transcription factor OC2 is a direct target of T-bet in type-1 T-helper cells
    K Furuno
    Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    Genes Immun 9:302-8. 2008
    ..These results suggest that not only cell-extrinsic regulation via the IFN-gamma/STAT1 pathway, but also cell-intrinsic transcriptional positive feedback loop between T-bet and OC2 could be involved in Th1 development...
  47. doi request reprint Education and imaging. Hepatobiliary and pancreatic: arteriovenous malformation of the pancreas
    K Yamamoto
    Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan
    J Gastroenterol Hepatol 23:498. 2008
  48. ncbi request reprint [A prospective study of vaccinal guidelines for children with refractory convulsive seizures--a nationwide multi-institutional questionnaire survey]
    K Iyoda
    No To Hattatsu 39:456-8. 2007
  49. ncbi request reprint Chronic posterior dislocation of the glenohumeral joint complicated by a fractured proximal humerus: a case report
    K Takase
    Department of Orthopedic Surgery, Tokyo Medical University, Japan
    J Orthop Surg (Hong Kong) 14:204-7. 2006
    ..At 20-month follow-up, the patient had no pain, and her shoulder range of motion was forward flexion 160 degrees, abduction 140 degrees, external rotation 40 degrees, and internal rotation L3...
  50. pmc Citrullinated fibrinogen detected as a soluble citrullinated autoantigen in rheumatoid arthritis synovial fluids
    Y Takizawa
    Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo, 1138655 Japan
    Ann Rheum Dis 65:1013-20. 2006
    ..Anti-citrullinated protein antibodies (ACPA) are specifically and frequently detected in sera of patients with rheumatoid arthritis (RA). Citrullinated fibrin or fibrinogen is a candidate autoantigen of such antibodies...
  51. ncbi request reprint Risk and prognostic factors for Japanese patients with chronic graft-versus-host disease after bone marrow transplantation
    Y Atsuta
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Tsurumai cho, Showa Ku, Nagoya, Japan
    Bone Marrow Transplant 37:289-96. 2006
    ..Our patients could not be accurately classified when the proposed prognostic models from Western countries were used, thus indicating the need for a different model to identify high-risk patients...
  52. pmc Differential regulation of Th1 responses and CD154 expression in human CD4+ T cells by IFN-alpha
    H Shibuya
    Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
    Clin Exp Immunol 132:216-24. 2003
    ....
  53. ncbi request reprint Morphological studies on the ageing and osteoarthritis of the articular cartilage in C57 black mice
    K Yamamoto
    Department of Orthopedic Surgery, Tokyo Medical University, Tokyo, Japan
    J Orthop Surg (Hong Kong) 13:8-18. 2005
    ..To study the cause and mechanism of joint degeneration in osteoarthritis, through histopathological and ultrastructural-histochemical experiments on the articular cartilage of the knees of the C57 black mouse...
  54. ncbi request reprint The ability of disease modifying antirheumatic drugs to induce and maintain improvement in patients with rheumatoid arthritis. epidemiology of DMARDs treatment in Japan
    M Nagashima
    Department of Joint Disease and Rheumatism, Nippon Medical School, Tokyo, Japan
    Clin Exp Rheumatol 23:27-35. 2005
    ....
  55. ncbi request reprint Reversible primary hypothyroidism in Japanese patients undergoing maintenance hemodialysis
    T Sanai
    Department of Cardiovascular and Renal Medicine, Saga University Faculty of Medicine, Saga, Japan
    Clin Nephrol 69:107-13. 2008
    ..Eight patients who had undergone treatment for thyroid disease before starting hemodialysis therapy, and 3 patients with amyloidosis due to rheumatoid arthritis were excluded...
  56. pmc A full genome scan for gastric cancer
    M Aoki
    J Med Genet 42:83-7. 2005
  57. pmc Identification of novel MUNC13-4 mutations in familial haemophagocytic lymphohistiocytosis and functional analysis of MUNC13-4-deficient cytotoxic T lymphocytes
    K Yamamoto
    Division of Molecular Population Genetics, Department of Molecular Genetics, Medical Institute of Bioregulation, and Kyushu University COE Programme on Lifestyle Related Diseases, Kyushu University, Japan
    J Med Genet 41:763-7. 2004
    ..FHL2 subtype with perforin (PRF1) mutation accounts for 30% of all FHL cases, while FHL with MUNC13-4 mutation was recently identified and designated as FHL3 subtype...
  58. ncbi request reprint Chronic expanding hematoma in combination with a pseudoaneurysm: a case report
    K Yamamoto
    Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Int Angiol 27:266-8. 2008
    ..These hematomas were termed as chronic expanding hematomas. In this report, we describe a case of chronic expanding hematoma with a pseudoaneurysm that underwent surgical biopsy, which led to an increase in its expansion speed...
  59. ncbi request reprint Association of the Pro90Ser CD36 mutation with elevated free fatty acid concentrations but not with insulin resistance syndrome in Japanese
    S Kajihara
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Saga Medical School, 5 1 1 Nabeshima, Saga 849 8501, Japan
    Clin Chim Acta 314:125-30. 2001
    ....
  60. ncbi request reprint Identification of the sequence responsible for the nuclear localization of human Cdc6
    Y Takei
    Division of Molecular Cell Pharmacology, National Children s Medical Research Center, Tokyo, Japan
    FEBS Lett 447:292-6. 1999
    ....
  61. ncbi request reprint Polymorphism of TAPASIN and its linkage disequilibria with HLA class II genes in the Japanese population
    H Furukawa
    Department of Research, Japanese Red Cross Central Blood Center, Tokyo, Japan
    Tissue Antigens 52:279-81. 1998
    ..Several frequent four-locus haplotypes were identified, including DRB1*0901-DQB1*0303-DPB1*0501-TAPASIN*02, DRB1*0901-DQB1*0303-DPB1*0201-TAPASIN*02 and DRB1*1302-DQB1*0604-DPB1*0401-TAPASIN*02...
  62. ncbi request reprint Cloning and characterization of a mouse homologue (mNthl1) of Escherichia coli endonuclease III
    A H Sarker
    Institute of Cellular and Molecular Biology, Okayama University Medical School, Okayama 700 8558, Japan
    J Mol Biol 282:761-74. 1998
    ..The mNthl1 gene was shown to lie immediately adjacent to the tuberous sclerosis 2 (Tsc2) gene in a 5'-to-5' orientation by sequence analysis and was assigned to chromosome 17A3 by in situ hybridization...
  63. ncbi request reprint Analysis of bilirubin uridine 5'-diphosphate (UDP)-glucuronosyltransferase gene mutations in seven patients with Crigler-Najjar syndrome type II
    K Yamamoto
    Second Department of Internal Medicine, Shiga University of Medical Science, Japan
    J Hum Genet 43:111-4. 1998
    ..Although the first and the second type of mutations are recessive, the third type appears to be dominant with incomplete penetrance, since the allele frequency of the insertion mutation of the TATAA element is very high (40%)...
  64. ncbi request reprint Expression of cathepsin E in pancreas: a possible tumor marker for pancreas, a preliminary report
    T Azuma
    Second Department of Internal Medicine, Fukui Medical School, Japan
    Int J Cancer 67:492-7. 1996
    ....
  65. ncbi request reprint Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
    W E Thierfelder
    Department of Biochemistry, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Nature 382:171-4. 1996
    ..However, all IL-12 functions tested were disrupted, including the induction of IFN-gamma, mitogenesis, enhancement of natural killer cytolytic function and Th1 differentiation...
  66. ncbi request reprint Cell cycle-dependent expression of the mouse Rad51 gene in proliferating cells
    A Yamamoto
    Department of Molecular Embryology, Research Institute of Microbial Diseases, Osaka, Japan
    Mol Gen Genet 251:1-12. 1996
    ..Thus, mouse Rad51 expression is closely related to the state of cell proliferation and is presumably involved in DNA repair coupled with DNA replication, as well as in meiotic DNA recombination in spermatocytes...
  67. ncbi request reprint Induction of IL-2 receptor expression and proliferation of T cell clones by a novel cytokine(s)
    T Kato
    Department of Allergology, University of Tokyo, Japan
    Cell Immunol 142:79-93. 1992
    ..These observations suggest that IL-2RIF activity is mediated by a novel cytokine(s) and the cytokine plays an important role as a second signal in the activation of the TH1 clone...
  68. pmc Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide
    F Samad
    Scripps Research Institute, Department of Vascular Biology, La Jolla, California 92037, USA
    J Clin Invest 97:37-46. 1996
    ..These studies suggest that the adipose tissue itself may be an important contributor to the elevated PAI-1 levels observed in the plasma under obese conditions...
  69. ncbi request reprint [An epidemiological study on chronicity and incidence of hepatocellular carcinoma in the sequence of epidemic hepatitis]
    K Naito
    Municipal Kumayama Hospital
    Kansenshogaku Zasshi 67:978-86. 1993
    ..8%, 41.4%, 34.5%, and 10.3%, respectively. In conclusion, it is suggested that the hepatitis epidemic in Kumayama Town was caused by HAV and superinfected by HCV and/or HBV, then its clinical manifestations became complicated...
  70. ncbi request reprint High conservation of subunit composition of RNA polymerase I(A) between yeast and mouse and the molecular cloning of mouse RNA polymerase I 40-kDa subunit RPA40
    C Z Song
    Department of Biochemistry, University of Tokyo School of Medicine, Japan
    J Biol Chem 269:26976-81. 1994
    ..The high conservation of this subunit among distant eukaryotes and different RNA polymerases suggests functional importance of this protein as a core subunit...
  71. pmc Exon redefinition by a point mutation within exon 5 of the glucose-6-phosphatase gene is the major cause of glycogen storage disease type 1a in Japan
    S Kajihara
    Department of Internal Medicine, Saga Medical School, Japan
    Am J Hum Genet 57:549-55. 1995
    ..This mutation is a new type of splicing mutation in the G6Pase gene, and 91% of patients and carriers suffering from GSD1a in Japan are detectable with this splicing mutation...
  72. ncbi request reprint Structural diversity of murine serum amyloid A genes. Evolutionary implications
    K Yamamoto
    J Immunol 139:1683-8. 1987
    ..Based on these results and the SAA gene arrangement, we discussed mouse SAA gene evolution...
  73. pmc Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins
    T Ito
    Human Genome Center, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    Proc Natl Acad Sci U S A 97:1143-7. 2000
    ..The approach described here thus will provide many leads for integration of various cellular functions and serve as a major driving force in the completion of the protein-protein interaction map...
  74. ncbi request reprint Molecular cloning of a novel type 1 cytokine receptor similar to the common gamma chain
    K Fujio
    Department of Hematopoietic Factors, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Blood 95:2204-10. 2000
    ..These results suggest that delta1 is a subunit of cytokine receptor that may be involved in multiple receptor systems and play a regulatory role in the immune system and hematopoiesis...
  75. ncbi request reprint The Fc gamma receptor genotype as a severity factor for chronic periodontitis in Japanese patients
    T Kobayashi
    Division of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    J Periodontol 72:1324-31. 2001
    ..The purpose of this study was to evaluate whether Fc gamma R polymorphisms are also associated with severity of CP...
  76. ncbi request reprint Early interleukin 4-dependent response can induce airway hyperreactivity before development of airway inflammation in a mouse model of asthma
    Y To
    Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Lab Invest 81:1385-96. 2001
    ..If this early increase in AHR does occur in sensitized human infants, it could be another therapeutic target for early prevention of the future onset of asthma...
  77. pmc Codon 201(Gly) polymorphic type of the DCC gene is related to disseminated neuroblastoma
    X T Kong
    Department of Pediatrics, Graduate School of Medicine, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    Neoplasia 3:267-72. 2001
    ..002). The results suggested that the codon 201(Gly) type of the DCC gene might be associated with a higher risk of disseminating neuroblastoma...
  78. ncbi request reprint Novel mode of transcription regulation by SdiA, an Escherichia coli homologue of the quorum-sensing regulator
    K Yamamoto
    Department of Molecular Genetics and Radioisotope Center, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
    Mol Microbiol 41:1187-98. 2001
    ..Neither alpha CTD nor sigma CTD are required for this inhibition. Thus, the transcription repression of P1 by SdiA may result from its competition with the RNA polymerase in binding to this promoter...
  79. ncbi request reprint Regulation of mouse mast cell surface Fc epsilon RI expression by dexamethasone
    M Yamaguchi
    Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    Int Immunol 13:843-51. 2001
    ....
  80. ncbi request reprint Home is where it begins: parents, children, and stressful events
    K Yamamoto
    University of Colorado, Denver, USA
    J Child Psychol Psychiatry 42:533-7. 2001
    ..79, and (3) the incidences with an r of .96. The striking contrasts with the earlier comparisons with professional judgements invite a reassessment of parents as dependable observer-reporters...
  81. ncbi request reprint Possible impact of treated wastewater discharge on incidence of antibiotic resistant bacteria in river water
    T Iwane
    Department of Urban Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8656, Japan
    Water Sci Technol 43:91-9. 2001
    ....
  82. ncbi request reprint Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells
    H Nakagami
    Department of Geriatric Medicine, Osaka University Medical School, Yamada-oka, Suita, Osaka, Japan
    Diabetes 50:1472-81. 2001
    ..Phosphorylation of p38 MAPK downstream of the bax-caspase pathway may play a pivotal role in endothelial apoptosis mediated by high D-glucose...
  83. ncbi request reprint [Three-dimensional CT angiography of the hepatic artery with multislice CT: differences in image quality according to scanning pitch]
    M Tanikake
    Department of Radiology, Osaka Medical College
    Nippon Igaku Hoshasen Gakkai Zasshi 61:172-4. 2001
    ..Evaluation was done visually, taking the sharpness of images of branches of the hepatic artery as a measure. Three-dimensional imaging scanned at pitch 3 tended to be better than that scanned at pitch 5.5...
  84. ncbi request reprint Regressive effect of intralesional injection of a moderate dose of recombinant interleukin-2 on carcinoma erysipeloides from gastric carcinoma
    Y Hamamoto
    Department of Dermatology, Yamaguchi University School of Medicine, Japan
    Clin Exp Dermatol 26:42-4. 2001
    ..These findings suggest that this cytokine should be considered for the clinical treatment of several inoperative metastatic cutaneous diseases, including gastric cancer...
  85. ncbi request reprint Isolation and characterization of the fission yeast gene Sprpa12+ reveals that the conserved C-terminal zinc-finger region is dispensable for the function of its product
    Y Imazawa
    Department of Biochemistry, Saitama Medical School, Moroyama, Japan
    Mol Gen Genet 264:852-9. 2001
    ..cerevisiae and S. pombe. Finally, the analysis of mutants suggests that SpRPA12 requires the zinc-finger domain in the N-terminal region but not the one in the C-terminal region for its function...
  86. pmc Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to t
    R Yamada
    Laboratory of Rheumatic Diseases, SNP Research Center, Institute of Physical and Chemical Research, Tokyo, Japan
    Am J Hum Genet 68:674-85. 2001
    ..The utility of combining the genotype data in this way to identify possible contributions of various genes to this disease is discussed...
  87. ncbi request reprint The Fcgamma receptor genotype as a risk factor for generalized early-onset periodontitis in Japanese patients
    T Kobayashi
    Department of Periodontology, Faculty of Dentistry, Niigata University, Japan
    J Periodontol 71:1425-32. 2000
    ..The purpose of this study was to evaluate whether FcgammaR polymorphisms are also associated with generalized early-onset periodontitis (G-EOP) in Japanese patients...
  88. ncbi request reprint Diverse gene expression for isotypes of murine serum amyloid A protein during acute phase reaction
    K Yamamoto
    Science 232:227-9. 1986
    ..Thus, the study emphasizes the importance of SAA gene structure in determining susceptibility to amyloidosis...