Research Topics
| Takeyuki TamuraSummaryAffiliation: Kyoto University Country: Japan Publications
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Detail Information
Publications
Integer programming-based method for completing signaling pathways and its application to analysis of colorectal cancerTakeyuki Tamura
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
Genome Inform 24:193-203. 2010..In this paper, we develop an integer programming-based method for inferring such changes by using gene expression data. We test our method on its ability to reconstruct the pathway of colorectal cancer in the KEGG database...
Analysis and prediction of nutritional requirements using structural properties of metabolic networks and support vector machinesTakeyuki Tamura
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
Genome Inform 22:176-90. 2010..Furthermore, we study which properties are influential to the nutritional requirements...
A clique-based method for the edit distance between unordered trees and its application to analysis of glycan structuresDaiji Fukagawa
Faculty of Culture and Information Science, Doshisha University, Kyoto 610 0394, Japan
BMC Bioinformatics 12:S13. 2011..However, it is known that computation of the edit distance for rooted unordered trees is NP-hard. Furthermore, there is almost no available software tool that can compute the exact edit distance for unordered trees...
Subcellular location prediction of proteins using support vector machines with alignment of block sequences utilizing amino acid compositionTakeyuki Tamura
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
BMC Bioinformatics 8:466. 2007..Since existing predictors are based on various heuristics, it is important to develop a simple method with high prediction accuracies...
Finding a periodic attractor of a Boolean networkTatsuya Akutsu
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto, Japan
IEEE/ACM Trans Comput Biol Bioinform 9:1410-21. 2012..For finding an attractor of a fixed period of a BN consisting of n nested canalyzing functions and having constant treewidth w, we present an O(n(2p(w+1))poly(n)) time algorithm...
Determining a singleton attractor of a boolean network with nested canalyzing functionsTatsuya Akutsu
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Kyot, Japan
J Comput Biol 18:1275-90. 2011..Finally, we present an o(2(n)) time algorithm for bounded degree BNs consisting of canalyzing functions...
Network completion using dynamic programming and least-squares fittingNatsu Nakajima
Bioinformatics Center, Institute for Chemical Research, Kyoto University Gokasho, Uji, Kyoto 611 0011, Japan
ScientificWorldJournal 2012:957620. 2012..We also perform computational experiments using both artificially generated and real gene expression time series data...
Compound analysis via graph kernels incorporating chiralityJ B Brown
Institute for Chemical Research, Kyoto University, Uji, Kyoto, Japan
J Bioinform Comput Biol 8:63-81. 2010....
A clique-based method using dynamic programming for computing edit distance between unordered treesTomoya Mori
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto, Japan
J Comput Biol 19:1089-104. 2012..For large tree-structures, the improved method is much faster than the previous method. In particular, for hard instances, the improved method achieved more than 100 times speed-up...
A dynamic programming algorithm to predict synthesis processes of tree-structured compounds with graph grammarYang Zhao
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto, 611 0011, Japan
Genome Inform 24:218-29. 2010..In order to represent rules corresponding to chemical reactions, we employ a subclass of NLC (Node Label Controlled) grammars. We also give some computational results on this algorithm...
