H Takebayashi

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. ncbi request reprint Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3
    H Takebayashi
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Yoshida, Konoe cho, Sakyo ku, 606 8501, Kyoto, Japan
    Mech Dev 99:143-8. 2000
  2. ncbi request reprint Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube
    Hirohide Takebayashi
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Yoshida, Konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Mech Dev 113:169-74. 2002
  3. ncbi request reprint The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages
    Hirohide Takebayashi
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Yoshida, Konoe cho, Sakyo ku, Japan
    Curr Biol 12:1157-63. 2002
  4. ncbi request reprint Sgn1, a basic helix-loop-helix transcription factor delineates the salivary gland duct cell lineage in mice
    S Yoshida
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Dev Biol 240:517-30. 2001
  5. ncbi request reprint Involvement of the Olig2 transcription factor in cholinergic neuron development of the basal forebrain
    Miki Furusho
    Department of Physiological Sciences, School of Life Science, The Graduate University for Advanced Studies Sokendai, Okazaki, Aichi 444 8787, Japan
    Dev Biol 293:348-57. 2006
  6. ncbi request reprint Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells
    Noritaka Masahira
    Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8787, Japan
    Dev Biol 293:358-69. 2006
  7. ncbi request reprint Expression of the basic helix-loop-factor Olig2 in the developing retina: Olig2 as a new marker for retinal progenitors and late-born cells
    Koji Shibasaki
    Center for Aging and Developmental Biology, University of Rochester, School of Medicine, Rochester, NY 14642, USA
    Gene Expr Patterns 7:57-65. 2007
  8. ncbi request reprint NG2 and Olig2 expression provides evidence for phenotypic deregulation of cultured central nervous system and peripheral nervous system neural precursor cells
    Cecile Dromard
    INSERM U583, Physiopathologie et Thérapie des Déficits Sensoriels et Moteurs Institut des Neurosciences de Montpellier, Hopital St Eloi, BP 74103 80, avenue Augustin Fliche 34091 Montpellier Cedex 05, France
    Stem Cells 25:340-53. 2007
  9. ncbi request reprint Regulation of glial development by cystatin C
    Akiko Hasegawa
    Department of Physiological Sciences, School of Life Science, The Graduate University for Advanced Studies Sokendai, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Aichi, Japan
    J Neurochem 100:12-22. 2007
  10. ncbi request reprint Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors
    Goichi Miyoshi
    Neuroscience Program and Department of Cell Biology, Smilow Research Center, New York University School of Medicine, New York, New York 10016, USA
    J Neurosci 27:7786-98. 2007

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3
    H Takebayashi
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Yoshida, Konoe cho, Sakyo ku, 606 8501, Kyoto, Japan
    Mech Dev 99:143-8. 2000
    ..These results indicate that Olig2 expression is not limited to the oligodendrocyte lineage but includes immature neuronal progenitors and multipotential neuron/glia progenitors as well as embryonic olfactory neurons...
  2. ncbi request reprint Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube
    Hirohide Takebayashi
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Yoshida, Konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Mech Dev 113:169-74. 2002
    ..5. Olig3 is specifically and transiently expressed in different types of progenitors of embryonic central nervous system and then disappears in the course of development...
  3. ncbi request reprint The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages
    Hirohide Takebayashi
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Yoshida, Konoe cho, Sakyo ku, Japan
    Curr Biol 12:1157-63. 2002
    ..Our data provide the first evidence that a single gene mutation leads to the loss of two cell types, motoneuron and oligodendrocyte...
  4. ncbi request reprint Sgn1, a basic helix-loop-helix transcription factor delineates the salivary gland duct cell lineage in mice
    S Yoshida
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Dev Biol 240:517-30. 2001
    ..In addition, Sgn1 expression exhibits a reverse relationship with the development of male phenotypes, suggesting its role in gender dimorphism in the salivary glands...
  5. ncbi request reprint Involvement of the Olig2 transcription factor in cholinergic neuron development of the basal forebrain
    Miki Furusho
    Department of Physiological Sciences, School of Life Science, The Graduate University for Advanced Studies Sokendai, Okazaki, Aichi 444 8787, Japan
    Dev Biol 293:348-57. 2006
    ..The present study provides the first direct evidence for involvement of the Olig2 gene in cholinergic differentiation in the basal forebrain...
  6. ncbi request reprint Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells
    Noritaka Masahira
    Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8787, Japan
    Dev Biol 293:358-69. 2006
    ..These findings demonstrate that motoneurons and oligodendrocytes are not the only cell types originating from this domain...
  7. ncbi request reprint Expression of the basic helix-loop-factor Olig2 in the developing retina: Olig2 as a new marker for retinal progenitors and late-born cells
    Koji Shibasaki
    Center for Aging and Developmental Biology, University of Rochester, School of Medicine, Rochester, NY 14642, USA
    Gene Expr Patterns 7:57-65. 2007
    ..Thus, Olig2 is an marker both for retinal progenitor cells during embryonic stages, and also for differentiated retinal subpopulations within the GCL and INL during postnatal stages...
  8. ncbi request reprint NG2 and Olig2 expression provides evidence for phenotypic deregulation of cultured central nervous system and peripheral nervous system neural precursor cells
    Cecile Dromard
    INSERM U583, Physiopathologie et Thérapie des Déficits Sensoriels et Moteurs Institut des Neurosciences de Montpellier, Hopital St Eloi, BP 74103 80, avenue Augustin Fliche 34091 Montpellier Cedex 05, France
    Stem Cells 25:340-53. 2007
    ..These data provide new evidence for profound phenotypic modifications in CNS and PNS neural precursor cells induced by culture conditions...
  9. ncbi request reprint Regulation of glial development by cystatin C
    Akiko Hasegawa
    Department of Physiological Sciences, School of Life Science, The Graduate University for Advanced Studies Sokendai, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Aichi, Japan
    J Neurochem 100:12-22. 2007
    ..The antibody increased the number of oligodendrocytes and their precursors. Therefore, CysC modifies glial development in addition to its activity against neural stem/precursor cells...
  10. ncbi request reprint Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors
    Goichi Miyoshi
    Neuroscience Program and Department of Cell Biology, Smilow Research Center, New York University School of Medicine, New York, New York 10016, USA
    J Neurosci 27:7786-98. 2007
    ..We observe that the physiological subtypes of cortical interneurons are, to a large degree, unique to their time point of generation...
  11. doi request reprint Regional- and temporal-dependent changes in the differentiation of Olig2 progenitors in the forebrain, and the impact on astrocyte development in the dorsal pallium
    Katsuhiko Ono
    Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, 5 1 Higashiyama, Myodaiji, Okazaki, Aichi 444 8787, Japan
    Dev Biol 320:456-68. 2008
    ..These observations indicate that embryonic Olig2+ progenitor cells change their differentiative properties during development, and also that Olig2 plays a role in astrocyte development in a region-specific manner...
  12. ncbi request reprint Basic fibroblast growth factor endows dorsal telencephalic neural progenitors with the ability to differentiate into oligodendrocytes but not gamma-aminobutyric acidergic neurons
    Masahiko Abematsu
    Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan
    J Neurosci Res 83:731-43. 2006
    ....
  13. doi request reprint Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex
    Leda Dimou
    Department of Physiological Genomics, Institute of Physiology, Ludwig Maximilians University Munich, 80336 Munich, Germany
    J Neurosci 28:10434-42. 2008
    ..Thus, our results demonstrate the continuous generation of mature, myelinating oligodendrocytes in the WM, whereas cells in the GM generated mostly postmitotic NG2(+) glia...
  14. ncbi request reprint Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation
    Hui Fu
    Department of Anatomical Sciences and Neurobiology, School of Medicine, University of Louisville, Louisville, KY 40292, USA
    Development 129:681-93. 2002
    ..In support of this suggestion, inhibition of expression of these two transcription factors in culture by antisense oligonucleotides has an additive inhibitory effect on OLP differentiation and proteolipid protein (PLP) gene expression...
  15. ncbi request reprint Evidence for a second wave of oligodendrogenesis in the postnatal cerebral cortex of the mouse
    Anna Ivanova
    Laboratory of Neural Information, National Institute for Physiological Sciences, Okazaki National Research Institutes, Aichi, Japan
    J Neurosci Res 73:581-92. 2003
    ..In the second wave, there might be two different types of precursor cells: PLP/DM20(+) cells populating only inner layers and PDGFRalpha(+) cells, which might eventually myelinate the outer regions as well...
  16. ncbi request reprint The potential to induce glial differentiation is conserved between Drosophila and mammalian glial cells missing genes
    Yasuno Iwasaki
    Division of Molecular Neurobiology, National Institute for Physiological Sciences, Okazaki, Aichi 444 8585, Japan
    Development 130:6027-35. 2003
    ..The mammalian homolog of Drosophila gcm, mouse Gcm1, exhibits the potential to induce gliogenesis, but may function in the generation of a minor subpopulation of glial cells...
  17. pmc Anti-human Olig2 antibody as a useful immunohistochemical marker of normal oligodendrocytes and gliomas
    Hideaki Yokoo
    Department of Pathology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Am J Pathol 164:1717-25. 2004
    ..Neither central neurocytoma nor schwannoma cases were stained. Our antibody was demonstrated to be useful in recognizing normal oligodendrocytes on paraffin sections, and applicable in diagnosis of some brain tumors...
  18. ncbi request reprint Converse control of oligodendrocyte and astrocyte lineage development by Sonic hedgehog in the chick spinal cord
    Eric Agius
    Centre de Biologie du Developpement, UMR5547 CNRS UPS, Universite Paul Sabatier, Toulouse, France
    Dev Biol 270:308-21. 2004
    ..We propose that specification of distinct glial lineages is the result of a choice that depends on Shh signalling...
  19. ncbi request reprint Short-term lineage analysis of dorsally derived Olig3 cells in the developing spinal cord
    Lei Ding
    Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, 5 1 Higashiyama, Myodaiji, Okazaki, 444 8787, Japan
    Dev Dyn 234:622-32. 2005
    ..Dorsal midline cells were also LacZ-positive during development. These findings suggest that dorsal Olig3 cells contribute to dorsal midline cells and commissural interneurons at intermediate and ventral levels...
  20. ncbi request reprint Gliogenic radial glial cells show heterogeneity in the developing mouse spinal cord
    Yasuhiro Ogawa
    Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, 5 1 Higashiyama, Myodaiji, Okazaki, Japan
    Dev Neurosci 27:364-77. 2005
    ..This raises the idea that astrocytes generated from different domains along the dorsoventral axis in the mouse spinal cord have distinct characteristics...
  21. ncbi request reprint Improved preservation of X-gal reaction product for electron microscopy using hydroxypropyl methacrylate
    Noritaka Masahira
    Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Okazaki, Aichi 444 8787, Japan
    Neurosci Lett 374:17-20. 2005
    ..The protocol presented here appears to be useful for lineage determination by TEM of all types of X-gal-stained tissues...
  22. ncbi request reprint Murine model of Alexander disease: analysis of GFAP aggregate formation and its pathological significance
    Kenji F Tanaka
    Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Okazaki 444 8787, Japan
    Glia 55:617-31. 2007
    ..These results indicate that the presence of GFAP aggregates containing mutant GFAP is not sufficient to induce a major phenotype of Alexander disease, even though it causes some abnormalities in the mouse...
  23. ncbi request reprint In vivo transcriptional profile analysis reveals RNA splicing and chromatin remodeling as prominent processes for adult neurogenesis
    Daniel A Lim
    Department of Neurological Surgery and Developmental and Stem Cell Biology Program, University of California, San Francisco, CA 94143, USA
    Mol Cell Neurosci 31:131-48. 2006
    ....